LOCUS AF152501 2406 bp mRNA linear HUM 14-NOV-2000
DEFINITION Homo sapiens protocadherin beta 8 (PCDH-beta8) mRNA, complete cds.
ACCESSION AF152501
VERSION AF152501.2
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2406)
AUTHORS Wu,Q. and Maniatis,T.
TITLE A striking organization of a large family of human neural
cadherin-like cell adhesion genes
JOURNAL Cell 97 (6), 779-790 (1999)
PUBMED 10380929
REFERENCE 2 (bases 1 to 2406)
AUTHORS Wu,Q. and Maniatis,T.
TITLE Human protocadherin genes
JOURNAL Unpublished
REFERENCE 3 (bases 1 to 2406)
AUTHORS Wu,Q. and Maniatis,T.
TITLE Direct Submission
JOURNAL Submitted (19-MAY-1999) Department of Molecular and Cellular
Biology, Harvard University, 7 Divinity Avenue, Cambridge, MA
02138, USA
REFERENCE 4 (bases 1 to 2406)
AUTHORS Wu,Q. and Maniatis,T.
TITLE Direct Submission
JOURNAL Submitted (14-NOV-2000) Department of Molecular and Cellular
Biology, Harvard University, 7 Divinity Avenue, Cambridge, MA
02138, USA
REMARK Sequence update by submitter
COMMENT On Nov 14, 2000 this sequence version replaced AF152501.1.
FEATURES Location/Qualifiers
source 1..2406
/db_xref="H-InvDB:HIT000071805"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="5"
/map="5q31"
gene 1..2406
/gene="PCDH-beta8"
CDS 1..2406
/gene="PCDH-beta8"
/function="cell-cell adhesion"
/note="member of the cadherin superfamily"
/codon_start=1
/product="protocadherin beta 8"
/protein_id="AAD43762.2"
/translation="MEASGKLICRQRQVLFSFLLLGLSLAGAAEPRSYSVVEETEGSS
FVTNLAKDLGLEQREFSRRGVRVVSRGNKLHLQLNQETADLLLNEKLDREDLCGHTEP
CVLRFQVLLESPFEFFQAELQVIDINDHSPVFLDKQMLVKVSESSPPGTAFPLKNAED
LDIGQNNIENYIISPNSYFRVLTRKRSDGRKYPELVLDNALDREEEAELRLTLTALDG
GSPPRSGTAQVYIEVVDVNDNAPEFQQPFYRVQISEDSPISFLVVKVSATDVDTGVNG
EISYSLFQASDEISKTFKVDFLTGEIRLKKQLDFEKFQSYEVNIEARDAGGFSGKCTV
LIQVIDVNDHAPEVTMSAFTSPIPENAPETVVALFSVSDLDSGENGKISCSIQEDLPF
LLKSSVGNFYTLLTETPLDRESRAEYNVTITVTDLGTPRLTTHLNMTVLVSDVNDNAP
AFTQTSYTLFVRENNSPALHIGSVSATDRDSGTNAQVTYSLLPPQDPHLPLASLVSIN
TDNGHLFALRSLDYEALQAFEFRVGASDRGSPALSSEALVRVLVLDANDNSPFVLYPL
QNGSAPCTELVPRAAEPGYLVTKVVAVDGDSGQNAWLSYQLLKATEPGLFGVWAHNGE
VRTARLLSERDAAKQRLVVLVKDNGEPPCSATATLHLLLVDGFSQPYLPLPEAAPAQG
QADSLTVYLVVALASVSSLFLFSVLLFVAVLLCRRSRAASVGRCSVPEGPFPGHLVDV
RGTGSLSQNYQYEVCLAGGSGTNEFQFLKPVLPNIQGHSFGPEMEQNSNFRNGFGFSL
QLK"
BASE COUNT 542 a 663 c 666 g 535 t
ORIGIN
1 atggaggcca gcgggaagct catttgcaga caaaggcaag tccttttttc ctttctcctt
61 ttgggcttat ctctggcggg cgcggcggaa cctagaagct attctgtggt ggaggaaact
121 gagggcagct cctttgtcac caatttagca aaggacctgg gtctggagca gagggaattc
181 tccaggcggg gggttagggt tgtttccaga gggaacaaac tacatttgca gctcaatcag
241 gagaccgcgg atttgttgct aaatgagaaa ttggaccgtg aggatctgtg cggtcacaca
301 gagccctgtg tgctacgttt ccaagtgttg ctagagagtc ccttcgagtt ttttcaagct
361 gagctgcaag taatagacat aaacgaccac tctccagtat ttctggacaa acaaatgttg
421 gtgaaagtat cagagagcag tcctcctggg actgcgtttc ctctgaagaa tgctgaagac
481 ttagatatag gccaaaacaa tattgagaac tatataatca gccccaactc ctattttcgg
541 gtcctcaccc gcaaacgcag tgatggcagg aaatacccag agctggtgct ggacaacgcg
601 ctggaccgag aggaagaagc tgagctcagg ttaacactca cagcactgga tggtggctct
661 ccgcccagat ctggcactgc tcaggtctac attgaagttg tcgatgtcaa tgataatgcc
721 cctgaatttc agcagccttt ctatagggtg cagatctctg aggacagtcc aataagcttc
781 ctggttgtga aggtctctgc cacggatgta gacacaggag tcaacggaga gatttcctat
841 tcacttttcc aagcttcaga tgagataagc aaaactttta aggtcgattt cttgacagga
901 gaaattcgac taaagaaaca acttgatttc gaaaaatttc agtcctatga agtcaatatc
961 gaggcgagag atgctggagg cttttctgga aaatgcaccg ttctgattca agtgatagat
1021 gtgaacgacc atgccccaga agttaccatg tctgcattta ccagcccaat acctgagaat
1081 gcgcctgaaa ctgtggttgc acttttcagt gtttcagacc ttgattcagg agaaaatggg
1141 aaaataagtt gctccattca ggaggatcta cccttcctcc tgaaatcttc tgtggggaac
1201 ttttacaccc tactaacaga gacaccacta gacagagaaa gcagagccga gtacaacgtc
1261 actatcaccg tcactgactt agggacaccc aggctgacaa cacatctcaa tatgaccgtg
1321 ctggtgtcgg acgtcaatga caacgccccc gccttcaccc aaacctccta caccctgttc
1381 gtccgcgaga acaacagccc cgccctgcac atcggcagcg tcagcgccac agacagagac
1441 tcgggcacca acgcccaggt cacctactcg ctgctgccgc cccaggatcc gcacctgccc
1501 ctcgcctccc tggtctccat caacacagac aacggccacc tgttcgccct caggtcgctg
1561 gactacgagg ccctgcaggc gttcgagttc cgggtgggcg cttcagaccg cggctccccg
1621 gctttgagca gcgaggcgct ggtgcgcgtg ctggtgctgg acgccaacga caactcgccc
1681 ttcgtgctgt acccgctgca gaatggctcc gcgccctgca ccgagctggt gccccgggcg
1741 gccgagccgg gctacctggt gaccaaggtg gtggcggtgg acggcgactc gggccagaac
1801 gcctggctgt cgtaccagct gctcaaggcc acggagcccg ggctgttcgg tgtgtgggcg
1861 cacaatggcg aggtgcgcac cgccaggctg ctgagcgagc gcgacgcggc caagcagagg
1921 ctggtggtgc tggtcaagga caatggcgag cctccgtgct cggccaccgc cacgctgcac
1981 ttgctcctgg tggacggctt ctcccagccc tacctgccgc ttccggaggc tgccccagcc
2041 cagggccagg ccgactctct caccgtctac ctggtggtgg cgttggcctc ggtgtcttcg
2101 ctcttcctct tctcggtgct cctgttcgtg gcggtgctgc tgtgtaggag gagcagggcg
2161 gcctcggtgg gtcgctgctc agtgcctgag ggcccctttc cagggcatct ggtggacgtg
2221 aggggcaccg ggagcctgtc tcagaactat cagtacgagg tgtgcctggc aggaggctca
2281 gggacgaatg agttccagtt cctgaaacca gtattaccta atattcaggg ccattctttt
2341 gggccagaaa tggaacaaaa ctctaacttt aggaatggct ttggtttcag ccttcagtta
2401 aagtaa
//