LOCUS AF152333 4578 bp mRNA linear HUM 22-JUL-1999
DEFINITION Homo sapiens protocadherin gamma B4 (PCDH-gamma-B4) mRNA, complete
cds.
ACCESSION AF152333
VERSION AF152333.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4578)
AUTHORS Wu,Q. and Maniatis,T.
TITLE A striking organization of a large family of human neural
cadherin-like cell adhesion genes
JOURNAL Cell 97 (6), 779-790 (1999)
PUBMED 10380929
REFERENCE 2 (bases 1 to 4578)
AUTHORS Wu,Q. and Maniatis,T.
TITLE Human protocadherin genes
JOURNAL Unpublished
REFERENCE 3 (bases 1 to 4578)
AUTHORS Wu,Q. and Maniatis,T.
TITLE Direct Submission
JOURNAL Submitted (17-MAY-1999) Department of Molecular and Cellular
Biology, Harvard University, 7 Divinity Avenue, Cambridge, MA
02138, USA
FEATURES Location/Qualifiers
source 1..4578
/db_xref="H-InvDB:HIT000071759"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="5"
/map="5q31"
/tissue_type="brain"
gene 1..4578
/gene="PCDH-gamma-B4"
CDS 1..2772
/gene="PCDH-gamma-B4"
/function="cell-cell adhesion"
/note="member of the cadherin superfamily"
/codon_start=1
/product="protocadherin gamma B4"
/protein_id="AAD43727.1"
/translation="MGSGAGELGRAERLPVLFLFLLSLFCPALCEQIRYRIPEEMPKG
SVVGNLATDLGFSVQELPTRKLRVSSEKPYFTVSAESGELLVSSRLDREEICGKKPAC
ALEFEAVAENPLNFYHVNVEIEDINDHTPKFTQNSFELQISESAQPGTRFILGSAHDA
DIGSNTLQNYQLSPSDHFSLINKEKSDGSKYPEMVLKTPLDREKQKSYHLTLTALDFG
APPLSSTAQIHVLVTDANDNAPVFSQDVYRVSLSENVYPGTTVLQVTATDQDEGVNAE
ITFSFSEASQITQFDLNSNTGEITVLNTLDFEEVKEYSIVLEARDGGGMIAQCTVEVE
VIDENDNAPEVIFQSLPNLIMEDAELGTHIALLKVRDKDSRHNGEVTCKLEGDVPFKI
LTSSRNTYKLVTDAVLDREQNPEYNITVTATDRGKPPLSSSSSITLHIGDVNDNAPVF
SQSSYIVHVAENNPPGASISQVRASDPDLGPNGQVSYCIMASDLEQRELSSYVSISAE
SGVVFAQRAFDHEQLRAFELTLQARDQGSPALSANVSLRVLVDDRNDNAPRVLYPALG
PDGSALFDMVPHAAEPGYLVTKVVAVDADSGHNAWLSYHVLQASEPGLFSLGLRTGEV
RTARALGDRDAVRQRLLVAVRDGGQPPLSATATLHLVFADSLQEVLPDITDRPDPSDL
QAELQFYLVVALALISVLFLVAMILAIALRLRRSSSPASWSCFQPGLCVKSESVVPPN
YSEGTLPYSYNLCVAHTGKTEFNFLKCSEQLSSGQDILCGDSSGALFPLCNSSELTSH
QQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQFDTEMLQAMILASASEAADGSST
LGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTNAAGKRDGKAPAGGNGNK
KKSGKKEKK"
BASE COUNT 1042 a 1319 c 1202 g 1015 t
ORIGIN
1 atggggagcg gcgccgggga gctgggccgg gctgagaggc tgccagtgct ctttctcttc
61 ctgctgtctt tgttctgccc ggcgctctgt gagcagatcc gctacaggat tcccgaggaa
121 atgcccaagg gctccgtagt ggggaacctc gccacggacc tggggttcag cgtccaggag
181 ttaccgactc gaaaactgcg cgtcagttcg gagaagcctt acttcaccgt gagcgcagag
241 agcggggagt tgcttgtgag cagcaggcta gacagggagg agatatgcgg gaagaagcca
301 gcttgtgctc tggaatttga ggctgttgct gaaaatccac tgaactttta tcacgtgaat
361 gtggagatcg aggacattaa tgaccacacg ccaaaattca cgcaaaattc ctttgagctg
421 caaataagtg agtctgcaca gcctggcaca cgatttatat taggatctgc ccatgatgcg
481 gatattggta gcaacacact gcagaattac caactcagtc ccagtgatca tttctcactg
541 ataaataaag agaaatcaga tggcagtaaa taccctgaga tggtattgaa gacacctttg
601 gacagagaaa agcagaaatc ctaccacttg actttgactg ccttggactt tggagctcca
661 cccctaagca gcactgcaca gatacacgtt ctagtgactg atgccaatga taatgctcca
721 gtgttcagtc aagacgtata cagggtgagc ctttcagaaa acgtgtaccc ggggaccacg
781 gtgctacagg tgactgccac ggaccaggat gagggtgtca atgccgagat tactttctct
841 ttcagtgaag ctagccagat cacccaattt gacctgaact ctaacaccgg ggaaattact
901 gttttaaata cattagattt tgaagaagtc aaagaatatt ccatagtttt ggaagcaagg
961 gacggtggag gaatgattgc gcaatgcaca gtggaggtag aagtcataga tgaaaatgac
1021 aacgccccag aagtgatatt ccagtctcta cccaacctaa ttatggagga cgccgagctg
1081 ggaacacata ttgctttgct caaagtccgt gacaaggatt ccagacacaa tggagaagtg
1141 acttgtaaat tggaaggtga tgttccattt aaaatattaa cttcttcaag aaacacgtat
1201 aaattagtga cagatgctgt tctagaccgc gagcagaatc cagagtacaa tataaccgtt
1261 acggcaacag atcggggcaa gcctcccctc tcctccagtt ccagcatcac cctgcacatt
1321 ggtgatgtaa atgacaacgc tccggttttc tcacagtctt cctatatagt ccacgtggcc
1381 gagaacaacc cgcctggagc ctctatttca caagtcaggg cttctgatcc ggacttgggg
1441 cccaacggcc aagtctctta ctgcatcatg gccagtgacc tggagcagcg ggagctgtca
1501 tcctacgtgt ccataagcgc ggagagcggg gtggtgttcg cgcagcgcgc cttcgaccac
1561 gagcagctgc gcgccttcga actcacactg caggcccgcg accagggctc gccagcgctc
1621 agcgcgaacg tgagcctgcg cgtgttagtg gacgaccgca acgacaatgc gccacgggtg
1681 ctgtaccccg cgctgggtcc cgacggctct gcgctcttcg atatggtgcc gcacgctgca
1741 gagcctggct acttggtgac caaggtagtg gcggtggacg cagactcagg acacaacgcc
1801 tggctgtcct accacgtgct gcaggctagc gagcccgggc tcttcagcct ggggctgcgc
1861 acgggcgaag tgcgcacagc gcgtgcctta ggcgacaggg acgccgtccg ccagcgcctt
1921 ctggtcgccg tgcgtgacgg tggacagcca ccactctcgg ccactgccac gttgcacctg
1981 gtcttcgccg acagcttgca ggaggtgctg ccggatatca ctgaccgccc cgacccctct
2041 gacctccagg ctgagctgca gttttaccta gtggtggcct tggccttgat ctcagtgctc
2101 ttcctcgtgg ccatgattct ggccattgcc ttgcgcctgc gacgctcctc cagccccgcc
2161 tcctggagct gcttccagcc tggtctctgt gttaaatccg aatccgtggt tccccccaac
2221 tacagcgagg ggactttgcc ttattcctac aatctatgtg ttgcacatac aggaaagacg
2281 gagtttaatt tcctaaaatg tagtgagcag ttgagttcag gacaagacat actttgcggt
2341 gattcatctg gggccttatt tccactttgt aattccagtg aattgacttc ccatcagcaa
2401 gccccgccca acacggactg gcgtttctct caggcccaga gacccggcac cagcggctcc
2461 caaaatggcg atgacaccgg cacctggccc aacaaccagt ttgacacaga gatgctgcaa
2521 gccatgatct tggcgtccgc cagtgaagct gctgatggga gctccaccct gggagggggt
2581 gccggcacca tgggattgag cgcccgctac ggaccccagt tcaccctgca gcacgtgccc
2641 gactaccgcc agaatgtcta catcccaggc agcaatgcca cactgaccaa cgcagctggc
2701 aagcgggatg gcaaggcccc agcaggtggc aatggcaaca agaagaagtc gggcaagaag
2761 gagaagaagt aacatggagg ccaggccaag agccacaggg cggcctctcc ccaaccagcc
2821 cagcttctcc ttacctgcac ccaggcctca gagtttcagg gctaaccccc agaatactgg
2881 taggggccaa ggccatgctc cccttgggaa acagaaacaa gtgcccagtc agcacctacc
2941 ccttcccccc cagggggttg aatatgcaaa agcagttccg ctgggaaccc ccatccaatc
3001 aactgctgta cccatggggg tagtggggtt actgtagaca ccaagaacca tttgccacac
3061 cccgtttagt tacagctgaa ctcctccatc ttccaaatca atcaggccca tccatcccat
3121 gcctccctcc tccccacccc actccaacag ttcctctttc ccgagtaagg tggttggggt
3181 gttgaagtac caagtaacct acaagcctcc tagttctgaa aagttggaag ggcatcatga
3241 cctcttggcc tctcctttga ttctcaatct tcccccaaag catggtttgg tgccagcccc
3301 ttcacctcct tccagagccc aagatcaatg ctcaagtttt ggaggacatg atcaccatcc
3361 ccatggtact gatgcttgct ggatttaggg agggcatttt gctaccaagc ctcttcccaa
3421 cgccctgggg accagtcttc tgttttgttt ttcattgttt gacgtttcca ctgcatgcct
3481 tgacttcccc cacctcctcc tcaaacaaga gactccactg catgttccaa gacagtatgg
3541 ggtggtaaga taaggaaggg aagtgtgtgg atgtggatgg tgggggcatg gacaaagctt
3601 gacacatcaa gttatcaagg ccttggagga ggctctgtat gtcctcaggg gactgacaac
3661 atcctccaga ttccagccat aaaccaataa ctaggctgga cccttcccac tacataatag
3721 ggctcagccc aggcagccag ctttgggctg agctaacagg accaatggat taaactggca
3781 tttcagtcca aggaagctcg aagcaggttt aggaccaggt ccccttgaga ggtcagaggg
3841 gcctctgtgg gtgctgggta ctccagaggt gccactggtg gaagggtcag cggagcccca
3901 gcaggaaggg tgggccagcc aggccattct tagtccctgg gttggggagg cagggagcta
3961 gggcagggac caaatgaaca gaaagtctca gcccaggatg gggcttcttc aacagggccc
4021 ctgccctcct gaagcctcag tccttcacct tgccaggtgc cgtttctctt ccgtgaaggc
4081 cactgcccag gtccccagtg cgccccctag tggccatagc ctggttaaag ttccccagtg
4141 cctccttgtg catagacctt cttctcccac ccccttctgc ccctgggtcc ccggccatcc
4201 agcggggctg ccagagaacc ccagacctgc ccttacagta gtgtagcgcc ccctccctct
4261 ttcggctggt gtagaatagc cagtagtgta gtgcggtgtg cttttacgtg atggcgggtg
4321 ggcagcgggc ggcgggctcc gcgcagccgt ctgtccttga tctgcccgcg gcggcccgtg
4381 ttgtgttttg tgctgtgtcc acgcgctaag gcgaccccct cccccgtact gacttctcct
4441 ataagcgctt ctcttcgcat agtcacgtag ctcccacccc accctcttcc tgtgtctcac
4501 gcaagtttta tactctaata tttatatggc tttttttctt cgacaaaaaa ataataaaac
4561 gtttcttctg aaaagctg
//