LOCUS AF152321 4605 bp mRNA linear HUM 22-JUL-1999
DEFINITION Homo sapiens protocadherin gamma A12 (PCDH-gamma-A12) mRNA,
complete cds.
ACCESSION AF152321
VERSION AF152321.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4605)
AUTHORS Wu,Q. and Maniatis,T.
TITLE A striking organization of a large family of human neural
cadherin-like cell adhesion genes
JOURNAL Cell 97 (6), 779-790 (1999)
PUBMED 10380929
REFERENCE 2 (bases 1 to 4605)
AUTHORS Wu,Q. and Maniatis,T.
TITLE Human protocadherin genes
JOURNAL Unpublished
REFERENCE 3 (bases 1 to 4605)
AUTHORS Wu,Q. and Maniatis,T.
TITLE Direct Submission
JOURNAL Submitted (17-MAY-1999) Department of Molecular and Cellular
Biology, Harvard University, 7 Divinity Avenue, Cambridge, MA
02138, USA
FEATURES Location/Qualifiers
source 1..4605
/db_xref="H-InvDB:HIT000071747"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="5"
/map="5q31"
/tissue_type="brain"
gene 1..4605
/gene="PCDH-gamma-A12"
CDS 1..2799
/gene="PCDH-gamma-A12"
/function="cell-cell adhesion"
/note="member of the cadherin superfamily"
/codon_start=1
/product="protocadherin gamma A12"
/protein_id="AAD43715.1"
/translation="MIPARLHRDYKGLVLLGILLGTLWETGCTQIRYSVPEELEKGSR
VGDISRDLGLEPRELAERGVRIIPRGRTQLFALNPRSGSLVTAGRIDREELCMGAIKC
QLNLDILMEDKVKIYGVEVEVRDINDNAPYFRESELEIKISENAATEMRFPLPHAWDP
DIGKNSLQSYELSPNTHFSLIVQNGADGSKYPELVLKRALDREEKAAHHLVLTASDGG
DPVRTGTARIRVMVLDANDNAPAFAQPEYRASVPENLALGTQLLVVNATDPDEGVNAE
VRYSFRYVDDKAAQVFKLDCNSGTISTIGELDHEESGFYQMEVQAMDNAGYSARAKVL
ITVLDVNDNAPEVVLTSLASSVPENSPRGTLIALLNVNDQDSEENGQVICFIQGNLPF
KLEKSYGNYYSLVTDIVLDREQVPSYNITVTATDRGTPPLSTETHISLNVADTNDNPP
VFPQASYSAYIPENNPRGVSLVSVTAHDPDCEENAQITYSLAENTIQGASLSSYVSIN
SDTGVLYALSSFDYEQFRDLQVKVMARDNGHPPLSSNVSLSLFVLDQNDNAPEILYPA
LPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYRLLKASEPGLFSVGLHTG
EVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADSIPQVLADLGSLESPA
NSETSDLTLYLVVAVAAVSCVFLAFVILLLALRLRRWHKSRLLQASGGGLTGAPASHF
VGVDGVQAFLQTYSHEVSLTTDSRKSHLIFPQPNYADMLVSQESFEKSEPLLLSGDSV
FSKDSHGLIEQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQFDTEMLQAMILASA
SEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTNAAGKRDGK
APAGGNGNKKKSGKKEKK"
BASE COUNT 1028 a 1389 c 1236 g 952 t
ORIGIN
1 atgattcctg cgcgactgca ccgggactac aaagggcttg tcctgctggg aatcctcctg
61 gggactctgt gggagaccgg atgcacccag atacgctatt cagttccgga agagctggag
121 aaaggctcta gggtgggcga catctccagg gacctggggc tggagccccg ggagctcgcg
181 gagcgcggag tccgcatcat ccccagaggt aggacgcagc ttttcgccct gaatccgcgc
241 agcggcagct tggtcacggc gggcaggata gaccgggagg agctctgtat gggggccatc
301 aagtgtcaat taaatctaga cattctgatg gaggataaag tgaaaatata tggagtagaa
361 gtagaagtaa gggacattaa cgacaatgcg ccttactttc gtgaaagtga attagaaata
421 aaaattagtg aaaatgcagc cactgagatg cggttccctc taccccacgc ctgggatccg
481 gatatcggga agaactctct gcagagctac gagctcagcc cgaacactca cttctccctc
541 atcgtgcaaa atggagccga cggtagtaag taccccgaat tggtgctgaa acgcgccctg
601 gaccgcgaag aaaaggctgc tcaccacctg gtccttacgg cctccgacgg gggcgacccg
661 gtgcgcacag gcaccgcgcg catccgcgtg atggttctgg atgcgaacga caacgcacca
721 gcgtttgctc agcccgagta ccgcgcgagc gttccggaga atctggcctt gggcacgcag
781 ctgcttgtag tcaacgctac cgaccctgac gaaggagtca atgcggaagt gaggtattcc
841 ttccggtatg tggacgacaa ggcggcccaa gttttcaaac tagattgtaa ttcagggaca
901 atatcaacaa taggggagtt ggaccacgag gagtcaggat tctaccagat ggaagtgcaa
961 gcaatggata atgcaggata ttctgcgcga gccaaagtcc tgatcactgt tctggacgtg
1021 aacgacaatg ccccagaagt ggtcctcacc tctctcgcca gctcggttcc cgaaaactct
1081 cccagaggga cattaattgc ccttttaaat gtaaatgacc aagattctga ggaaaacgga
1141 caggtgatct gtttcatcca aggaaatctg ccctttaaat tagaaaaatc ttacggaaat
1201 tactatagtt tagtcacaga catagtcttg gatagggaac aggttcctag ctacaacatc
1261 acagtgaccg ccactgaccg gggaaccccg cccctatcca cggaaactca tatctcgctg
1321 aacgtggcag acaccaacga caacccgccg gtcttccctc aggcctccta ttccgcttat
1381 atcccagaga acaatcccag aggagtttcc ctcgtctctg tgaccgccca cgaccccgac
1441 tgtgaagaga acgcccagat cacttattcc ctggctgaga acaccatcca aggggcaagc
1501 ctatcgtcct acgtgtccat caactccgac actggggtac tgtatgcgct gagctccttc
1561 gactacgagc agttccgaga cttgcaagtg aaagtgatgg cgcgggacaa cgggcacccg
1621 cccctcagca gcaacgtgtc gttgagcctg ttcgtgctgg accagaacga caatgcgccc
1681 gagatcctgt accccgccct ccccacggac ggttccactg gcgtggagct ggctccccgc
1741 tccgcagagc ccggctacct ggtgaccaag gtggtggcgg tggacagaga ctccggccag
1801 aacgcctggc tgtcctaccg tctgctcaag gccagcgagc cgggactctt ctcggtgggt
1861 ctgcacacgg gcgaggtgcg cacggcgcga gccctgctgg acagagacgc gctcaagcag
1921 agcctcgtag tggccgtcca ggaccacggc cagccccctc tctccgccac tgtcacgctc
1981 accgtggccg tggccgacag catcccccaa gtcctggcgg acctcggcag cctcgagtct
2041 ccagctaact ctgaaacctc agacctcact ctgtacctgg tggtagcggt ggccgcggtc
2101 tcctgcgtct tcctggcctt cgtcatcttg ctgctggcgc tcaggctgcg gcgctggcac
2161 aagtcacgcc tgctgcaggc ttcaggaggc ggcttgacag gagcgccggc gtcgcacttt
2221 gtgggcgtgg acggggtgca ggctttcctg cagacctatt cccacgaggt ttccctcacc
2281 acggactcgc ggaagagtca cctgatcttc ccccagccca actatgcaga catgctcgtc
2341 agccaggaga gctttgaaaa aagcgagccc cttttgctgt caggtgattc ggtattttct
2401 aaagacagtc atgggttaat tgagcaagcc ccgcccaaca cggactggcg tttctctcag
2461 gcccagagac ccggcaccag cggctcccaa aatggcgatg acaccggcac ctggcccaac
2521 aaccagtttg acacagagat gctgcaagcc atgatcttgg cgtccgccag tgaagctgct
2581 gatgggagct ccaccctggg agggggtgcc ggcaccatgg gattgagcgc ccgctacgga
2641 ccccagttca ccctgcagca cgtgcccgac taccgccaga atgtctacat cccaggcagc
2701 aatgccacac tgaccaacgc agctggcaag cgggatggca aggccccagc aggtggcaat
2761 ggcaacaaga agaagtcggg caagaaggag aagaagtaac atggaggcca ggccaagagc
2821 cacagggcgg cctctcccca accagcccag cttctcctta cctgcaccca ggcctcagag
2881 tttcagggct aacccccaga atactggtag gggccaaggc catgctcccc ttgggaaaca
2941 gaaacaagtg cccagtcagc acctacccct tcccccccag ggggttgaat atgcaaaagc
3001 agttccgctg ggaaccccca tccaatcaac tgctgtaccc atgggggtag tggggttact
3061 gtagacacca agaaccattt gccacacccc gtttagttac agctgaactc ctccatcttc
3121 caaatcaatc aggcccatcc atcccatgcc tccctcctcc ccaccccact ccaacagttc
3181 ctctttcccg agtaaggtgg ttggggtgtt gaagtaccaa gtaacctaca agcctcctag
3241 ttctgaaaag ttggaagggc atcatgacct cttggcctct cctttgattc tcaatcttcc
3301 cccaaagcat ggtttggtgc cagccccttc acctccttcc agagcccaag atcaatgctc
3361 aagttttgga ggacatgatc accatcccca tggtactgat gcttgctgga tttagggagg
3421 gcattttgct accaagcctc ttcccaacgc cctggggacc agtcttctgt tttgtttttc
3481 attgtttgac gtttccactg catgccttga cttcccccac ctcctcctca aacaagagac
3541 tccactgcat gttccaagac agtatggggt ggtaagataa ggaagggaag tgtgtggatg
3601 tggatggtgg gggcatggac aaagcttgac acatcaagtt atcaaggcct tggaggaggc
3661 tctgtatgtc ctcaggggac tgacaacatc ctccagattc cagccataaa ccaataacta
3721 ggctggaccc ttcccactac ataatagggc tcagcccagg cagccagctt tgggctgagc
3781 taacaggacc aatggattaa actggcattt cagtccaagg aagctcgaag caggtttagg
3841 accaggtccc cttgagaggt cagaggggcc tctgtgggtg ctgggtactc cagaggtgcc
3901 actggtggaa gggtcagcgg agccccagca ggaagggtgg gccagccagg ccattcttag
3961 tccctgggtt ggggaggcag ggagctaggg cagggaccaa atgaacagaa agtctcagcc
4021 caggatgggg cttcttcaac agggcccctg ccctcctgaa gcctcagtcc ttcaccttgc
4081 caggtgccgt ttctcttccg tgaaggccac tgcccaggtc cccagtgcgc cccctagtgg
4141 ccatagcctg gttaaagttc cccagtgcct ccttgtgcat agaccttctt ctcccacccc
4201 cttctgcccc tgggtccccg gccatccagc ggggctgcca gagaacccca gacctgccct
4261 tacagtagtg tagcgccccc tccctctttc ggctggtgta gaatagccag tagtgtagtg
4321 cggtgtgctt ttacgtgatg gcgggtgggc agcgggcggc gggctccgcg cagccgtctg
4381 tccttgatct gcccgcggcg gcccgtgttg tgttttgtgc tgtgtccacg cgctaaggcg
4441 accccctccc ccgtactgac ttctcctata agcgcttctc ttcgcatagt cacgtagctc
4501 ccaccccacc ctcttcctgt gtctcacgca agttttatac tctaatattt atatggcttt
4561 ttttcttcga caaaaaaata ataaaacgtt tcttctgaaa agctg
//