LOCUS AF152318 4602 bp mRNA linear HUM 22-JUL-1999
DEFINITION Homo sapiens protocadherin gamma A1 (PCDH-gamma-A1) mRNA, complete
cds.
ACCESSION AF152318
VERSION AF152318.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4602)
AUTHORS Wu,Q. and Maniatis,T.
TITLE A striking organization of a large family of human neural
cadherin-like cell adhesion genes
JOURNAL Cell 97 (6), 779-790 (1999)
PUBMED 10380929
REFERENCE 2 (bases 1 to 4602)
AUTHORS Wu,Q. and Maniatis,T.
TITLE Human protocadherin genes
JOURNAL Unpublished
REFERENCE 3 (bases 1 to 4602)
AUTHORS Wu,Q. and Maniatis,T.
TITLE Direct Submission
JOURNAL Submitted (17-MAY-1999) Department of Molecular and Cellular
Biology, Harvard University, 7 Divinity Avenue, Cambridge, MA
02138, USA
FEATURES Location/Qualifiers
source 1..4602
/db_xref="H-InvDB:HIT000071744"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="5"
/map="5q31"
/tissue_type="brain"
gene 1..4602
/gene="PCDH-gamma-A1"
CDS 1..2796
/gene="PCDH-gamma-A1"
/function="cell-cell adhesion"
/note="member of the cadherin superfamily"
/codon_start=1
/product="protocadherin gamma A1"
/protein_id="AAD43712.1"
/translation="MKIQKKLTGCSRLMLLCLSLELLLEAGAGNIHYSVPEETDKGSF
VGNIAKDLGLQPQELADGGVRIVSRGRMPLFALNPRSGSLITARRIDREELCAQSMPC
LVSFNILVEDKMKLFPVEVEIIDINDNTPQFQLEELEFKMNEITTPGTRVSLPFGQDL
DVGMNSLQSYQLSSNPHFSLDVQQGADGPQHPEMVLQSPLDREEEAVHHLILTASDGG
EPVRSGTLRIYIQVVDANDNPPAFTQAQYHINVPENVPLGTQLLMVNATDPDEGANGE
VTYSFHNVDHRVAQIFRLDSYTGEISNKEPLDFEEYKMYSMEVQAQDGAGLMAKVKVL
IKVLDVNDNAPEVTITSVTTAVPENFPPGTIIALISVHDQDSGDNGYTTCFIPGNLPF
KLEKLVDNYYRLVTERTLDRELISGYNITITAIDQGTPALSTETHISLLVTDINDNSP
VFHQDSYSAYIPENNPRGASIFSVRAHDLDSNENAQITYSLIEDTIQGAPLSAYLSIN
SDTGVLYALRSFDYEQFRDMQLKVMARDSGDPPLSSNVSLSLFLLDQNDNAPEILYPA
LPTDGSTGVELAPLSAEPGYLVTKVVAVDRDSGQNAWLSYRLLKASEPGLFSVGLHTG
EVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADRISDILADLGSLEPSA
KPNDSDLTLYLVVAAAAVSCVFLAFVIVLLAHRLRRWHKSRLLQASGGGLASMPGSHF
VGVDGVRAFLQTYSHEVSLTADSRKSHLIFPQPNYADTLISQESCEKKGFLSAPQSLL
EDKKEPFSQQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQFDTEMLQAMILASAS
EAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTNAAGKRDGKA
PAGGNGNKKKSGKKEKK"
BASE COUNT 1075 a 1355 c 1167 g 1005 t
ORIGIN
1 atgaagattc agaaaaagct gactggctgc agcaggctga tgcttctgtg tctttctctg
61 gagctgctgt tggaagctgg ggctgggaat attcactact cagtgccgga agagacagac
121 aaaggttcct tcgtaggcaa catcgccaag gacctagggc tgcaacccca ggagctggca
181 gatggcggag tccgcatcgt ctccagaggt aggatgccgc ttttcgctct gaatcctaga
241 agtggcagct tgatcaccgc gcgcaggata gaccgggagg agctctgcgc tcagagcatg
301 ccgtgtctcg tgagttttaa tatccttgtt gaggataaaa tgaagctttt tcctgttgaa
361 gtagaaataa ttgatattaa tgacaacact ccccaattcc agttagagga actggagttt
421 aaaatgaatg aaataacgac tccaggtacc agagtctcat tgccttttgg gcaagacctt
481 gatgtgggta tgaactcact ccagagctac caactcagct ctaaccctca tttctccctg
541 gatgtgcaac agggagccga tgggcctcaa catccagaga tggtgctgca gagtccctta
601 gacagagaag aagaagctgt ccaccacctc atcctcacag cttctgatgg gggtgaacca
661 gtccgttcag ggaccctcag aatttacatt caggtggtgg atgcaaatga caatcctcca
721 gcatttactc aggcacaata ccatataaat gtccccgaaa acgtgccgct gggtactcag
781 ctgctcatgg taaatgccac tgaccctgat gagggagcca atggggaagt aacgtactcc
841 tttcacaatg tagaccacag agtggcccaa atatttcgtt tagattctta cacaggagaa
901 atatcaaata aagaaccact agatttcgaa gaatacaaaa tgtattcaat ggaagttcaa
961 gcccaggatg gtgcggggct catggctaaa gttaaggtac tgatcaaagt tttggatgta
1021 aatgataatg ccccagaagt gaccatcacc tctgtcacca ctgcagttcc agaaaacttt
1081 cctcctggga ccataattgc tcttatcagt gtgcatgacc aggactcagg agacaatggc
1141 tacaccacat gtttcattcc tggaaattta ccctttaaat tggaaaagtt agttgataat
1201 tattaccgtt tagtgactga aagaacactg gacagagaac ttatctctgg gtacaacatc
1261 acaataacag caatagacca aggaactcca gctctatcta ctgaaactca catttcacta
1321 ctagtgacag atatcaatga caactcccca gtcttccatc aggactccta ctctgcctac
1381 attcccgaaa acaaccccag aggagcctcc atcttctctg tgagggccca cgacttggac
1441 agcaatgaga atgcacaaat cacttactcc ctaatagagg acactatcca gggggcaccc
1501 ctatctgcct acctctccat caactccgac actggggtcc tgtatgcgct gcgatccttc
1561 gactatgagc agttccggga catgcaactg aaagtgatgg cgcgggacag tggggatccg
1621 cccctcagca gcaacgtgtc tctcagccta ttcctgctgg accagaacga caacgcgccc
1681 gagatcctgt accccgccct ccccacagat ggttctaccg gcgtggagct ggcgcccctc
1741 tccgcagagc ccggctacct ggtgaccaag gtggtggcgg tggacagaga ctcgggccag
1801 aacgcctggc tgtcctaccg cctgctcaag gccagcgagc cgggactctt ctcggtgggt
1861 ctgcacacgg gcgaggtgcg cacggcgcga gccctgctgg acagagacgc gctcaagcag
1921 agtctcgtgg tggccgtcca ggaccacggc cagcccccgc tctccgccac tgtcacgctc
1981 accgtggccg tggccgacag gatctccgac atcctggccg acctgggcag cctcgagccc
2041 tccgccaaac ccaacgattc ggacctcact ctgtacctgg tggtggcggc ggccgcggtc
2101 tcctgcgtct tcctggcctt cgtcatcgtg ctgctggcgc acaggctgcg gcgctggcac
2161 aagtcacgtc tgctacaggc ttcgggaggc ggcttagcga gcatgcccgg ttcgcacttt
2221 gtgggcgtgg acggggttcg ggctttcctg cagacctatt cccacgaggt ctccctcact
2281 gcggactcgc ggaagagcca cctgattttc ccccagccca actatgcgga cacactcatc
2341 agccaggaga gctgtgagaa aaagggtttt ctatcagcac cccagtcttt acttgaagac
2401 aaaaaggaac cattttctca gcaagccccg cccaacacgg actggcgttt ctctcaggcc
2461 cagagacccg gcaccagcgg ctcccaaaat ggcgatgaca ccggcacctg gcccaacaac
2521 cagtttgaca cagagatgct gcaagccatg atcttggcgt ccgccagtga agctgctgat
2581 gggagctcca ccctgggagg gggtgccggc accatgggat tgagcgcccg ctacggaccc
2641 cagttcaccc tgcagcacgt gcccgactac cgccagaatg tctacatccc aggcagcaat
2701 gccacactga ccaacgcagc tggcaagcgg gatggcaagg ccccagcagg tggcaatggc
2761 aacaagaaga agtcgggcaa gaaggagaag aagtaacatg gaggccaggc caagagccac
2821 agggcggcct ctccccaacc agcccagctt ctccttacct gcacccaggc ctcagagttt
2881 cagggctaac ccccagaata ctggtagggg ccaaggccat gctccccttg ggaaacagaa
2941 acaagtgccc agtcagcacc taccccttcc cccccagggg gttgaatatg caaaagcagt
3001 tccgctggga acccccatcc aatcaactgc tgtacccatg ggggtagtgg ggttactgta
3061 gacaccaaga accatttgcc acaccccgtt tagttacagc tgaactcctc catcttccaa
3121 atcaatcagg cccatccatc ccatgcctcc ctcctcccca ccccactcca acagttcctc
3181 tttcccgagt aaggtggttg gggtgttgaa gtaccaagta acctacaagc ctcctagttc
3241 tgaaaagttg gaagggcatc atgacctctt ggcctctcct ttgattctca atcttccccc
3301 aaagcatggt ttggtgccag ccccttcacc tccttccaga gcccaagatc aatgctcaag
3361 ttttggagga catgatcacc atccccatgg tactgatgct tgctggattt agggagggca
3421 ttttgctacc aagcctcttc ccaacgccct ggggaccagt cttctgtttt gtttttcatt
3481 gtttgacgtt tccactgcat gccttgactt cccccacctc ctcctcaaac aagagactcc
3541 actgcatgtt ccaagacagt atggggtggt aagataagga agggaagtgt gtggatgtgg
3601 atggtggggg catggacaaa gcttgacaca tcaagttatc aaggccttgg aggaggctct
3661 gtatgtcctc aggggactga caacatcctc cagattccag ccataaacca ataactaggc
3721 tggacccttc ccactacata atagggctca gcccaggcag ccagctttgg gctgagctaa
3781 caggaccaat ggattaaact ggcatttcag tccaaggaag ctcgaagcag gtttaggacc
3841 aggtcccctt gagaggtcag aggggcctct gtgggtgctg ggtactccag aggtgccact
3901 ggtggaaggg tcagcggagc cccagcagga agggtgggcc agccaggcca ttcttagtcc
3961 ctgggttggg gaggcaggga gctagggcag ggaccaaatg aacagaaagt ctcagcccag
4021 gatggggctt cttcaacagg gcccctgccc tcctgaagcc tcagtccttc accttgccag
4081 gtgccgtttc tcttccgtga aggccactgc ccaggtcccc agtgcgcccc ctagtggcca
4141 tagcctggtt aaagttcccc agtgcctcct tgtgcataga ccttcttctc ccaccccctt
4201 ctgcccctgg gtccccggcc atccagcggg gctgccagag aaccccagac ctgcccttac
4261 agtagtgtag cgccccctcc ctctttcggc tggtgtagaa tagccagtag tgtagtgcgg
4321 tgtgctttta cgtgatggcg ggtgggcagc gggcggcggg ctccgcgcag ccgtctgtcc
4381 ttgatctgcc cgcggcggcc cgtgttgtgt tttgtgctgt gtccacgcgc taaggcgacc
4441 ccctcccccg tactgacttc tcctataagc gcttctcttc gcatagtcac gtagctccca
4501 ccccaccctc ttcctgtgtc tcacgcaagt tttatactct aatatttata tggctttttt
4561 tcttcgacaa aaaaataata aaacgtttct tctgaaaagc tg
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