LOCUS AF151978 4520 bp mRNA linear HUM 18-AUG-1999
DEFINITION Homo sapiens amino acid transporter B0+ (ATB0+) mRNA, complete cds.
ACCESSION AF151978
VERSION AF151978.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4520)
AUTHORS Sloan,J.L. and Mager,S.
TITLE Cloning and functional expression of a human Na(+) and
Cl(-)-dependent neutral and cationic amino acid transporter B(0+)
JOURNAL J. Biol. Chem. 274 (34), 23740-23745 (1999)
PUBMED 10446133
REFERENCE 2 (bases 1 to 4520)
AUTHORS Sloan,J.L. and Mager,S.
TITLE Direct Submission
JOURNAL Submitted (17-MAY-1999) Cell and Molecular Physiology, University
of North Carolina, CB 7545, 460 MSRB, Chapel Hill, NC 27514, USA
FEATURES Location/Qualifiers
source 1..4520
/db_xref="H-InvDB:HIT000071724"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="X"
/map="Xq23-q24"
/tissue_type="mammary gland"
gene 1..4520
/gene="ATB0+"
CDS 89..2017
/gene="ATB0+"
/note="transports zwitterionic and cationic amino acids in
Na+ and Cl- dependent manner; highest expression in lung,
trachea, and salivary gland;
lower expression in the mammary gland, stomach, and
pituitary gland; very low expression in the colon,
prostate, uterus, and testis"
/codon_start=1
/product="amino acid transporter B0+"
/protein_id="AAD49223.1"
/translation="MDKLKCPSFFKCREKEKVSASSENFHVGENDENQDRGNWSKKSD
YLLSMIGYAVGLGNVWRFPYLTYSNGGGAFLIPYAIMLALAGLPLFFLECSLGQFASL
GPVSVWRILPLFQGVGITMVLISIFVTIYYNVIIAYSLYYMFASFQSELPWKNCSSWS
DKNCSRSPIVTHCNVSTVNKGIQEIIQMNKSWVDINNFTCINGSEIYQPGQLPSEQYW
NKVALQRSSGMNETGVIVWYLALCLLLAWLIVGAALFKGIKSSGKVVYFTALFPYVVL
LILLVRGATLEGASKGISYYIGAQSNFTKLKEAEVWKDAATQIFYSLSVAWGGLVALS
SYNKFKNNCFSDAIVVCLTNCLTSVFAGFAIFSILGHMAHISGKEVSQVVKSGFDLAF
IAYPEALAQLPGGPFWSILFFFMLLTLGLDSQFASIETITTTIQDLFPKVMKKMRVPI
TLGCCLVLFLLGLVCVTQAGIYWVHLIDHFCAGWGILIAAILELVGIIWIYGGNRFIE
DTEMMIGAKRWIFWLWWRACWFVITPILLIAIFIWSLVQFHRPNYGAIPYPDWGVALG
WCMIVFCIIWIPIMAIIKIIQAKGNIFQRLISCCRPASNWGPYLEQHRGERYKDMVDP
KKEADHEIPTVSGSRKPE"
BASE COUNT 1331 a 752 c 925 g 1512 t
ORIGIN
1 taggaacagg ggagagtgca cctgctacca gtcaagctca gccagactgc aagaggaggc
61 gaggcggagc cagccgaggg agtgaaccat ggacaagttg aaatgcccga gtttcttcaa
121 gtgcagggag aaggagaaag tgtcggcttc atcagagaat ttccatgttg gtgaaaatga
181 tgagaatcag gaccgtggta actggtccaa aaaatcggat tatcttctat ctatgattgg
241 atacgcagtg ggattaggaa atgtgtggag atttccatat ctgacctaca gcaatggtgg
301 aggcgccttc ttgatacctt atgcaattat gttagcattg gctggtttac ctttgttctt
361 tctggagtgt tcactgggac aatttgctag cttaggtcca gtttcagttt ggaggattct
421 tccattgttt caaggtgtgg gaattacaat ggtcctgatc tccatttttg tgacaatcta
481 ttacaatgtc ataattgcct atagtcttta ctacatgttt gcttcttttc aaagtgaact
541 accatggaaa aattgttctt cgtggtcaga taaaaactgt agcagatcac caatagtaac
601 tcactgtaat gtgagtacag tgaataaagg aatacaagag atcatccaaa tgaataaaag
661 ctgggtagac atcaacaatt ttacctgcat caacggcagt gaaatttatc agccagggca
721 gcttcccagt gaacaatatt ggaataaagt ggcgctccaa cggtcaagtg gaatgaatga
781 gactggagta attgtttggt atttagcact ttgtcttctt ctggcttggc tcatagttgg
841 agcagcacta tttaaaggaa tcaaatcgtc tggcaaggtg gtatatttta cagctctttt
901 cccctatgtg gtcctactca tcctgttagt acgaggtgca actctggagg gtgcttcaaa
961 aggcatttca tactatattg gagcccagtc aaattttaca aaacttaagg aagctgaggt
1021 atggaaagat gctgccactc agatatttta ctccctttca gtggcttggg gtggcttagt
1081 tgctctatca tcttacaata agttcaaaaa caactgcttc tctgatgcca ttgtggtttg
1141 tttgacaaac tgtctcacta gcgtgtttgc tggatttgct attttttcta tattgggaca
1201 catggcccat atatctggaa aggaagtttc tcaagttgta aaatcaggtt ttgatttggc
1261 attcattgcc tatccagagg ctctagccca actcccaggt ggtccatttt ggtccatatt
1321 attttttttc atgcttttaa ctttgggtct cgattctcag tttgcttcga ttgaaacgat
1381 cacaacaaca attcaagatt tatttcccaa agtgatgaag aaaatgaggg ttcccataac
1441 tttgggctgc tgcttggttt tgtttctcct tggtctcgtc tgtgtgactc aggctggaat
1501 ttactgggtt catctgattg accacttctg tgctggatgg ggcattttaa ttgcagctat
1561 actggagcta gttggaatca tctggattta tggagggaac agattcattg aggatacaga
1621 aatgatgatt ggagcaaaga ggtggatatt ctggctatgg tggagagctt gctggtttgt
1681 aattacgcct atccttttga ttgcaatatt tatctggtca ttggtgcaat ttcatagacc
1741 taattatggc gcaattccat accctgactg gggagttgct ttaggctggt gtatgattgt
1801 tttctgcatt atttggatac caattatggc tatcataaaa ataattcagg ctaaaggaaa
1861 catctttcaa cgccttataa gttgctgcag accagcttct aactggggtc catacctgga
1921 acaacatcgt ggggaaagat ataaagacat ggtagatcct aaaaaagagg ctgaccatga
1981 aatacctact gttagtggca gcagaaaacc ggaatgagat ctcattgaaa aaaatatatg
2041 attgtataat gtgatttttt ttagaatagg gggaacctta tttatttgtg tgttaactga
2101 ataggaaaat gtacatacta tgttcatgat agtgtgattt ttttcacatt taagcaggaa
2161 tgcaatataa aaatgtgaat ctcttaattc tcagccatgt gcttattata tttcttttta
2221 gattgtctat ctgtataaca cacacacaca cacctaagag tctctatttc acaattatat
2281 ttttgtaaat agtatatgca tttttaatac attggaggct ttattttgaa ctaatttctt
2341 agagaatagt tatattttct attacacaag tttaaaaata ttattaactt gtattttctt
2401 aatatacaat ctatcttttc cacaaatatg agtgggaaat aaatcagcac atttgaaaga
2461 aagtgttaaa actgaaggcc tcacttaatt agaaacgtga taaatatatg gacaaatgga
2521 ctatacatac tataagagga ctgtagttta atacttttta cccaaatatg tttaaaaaca
2581 tcgtgcattt gttacagctc atgttttcta tatgaactta gtcattaatg ttctttataa
2641 aaagtgaaat aagatggaaa aattaggatc ctacagccag tacgtgataa atctagaaaa
2701 ttgagttttg agtacctctt ttcccatata caatcttcct tccttaggta atttggaaga
2761 aaactatgac ccatttaatt tctattgtgt ttcaccaaat tcagtgttgt tcattatacc
2821 tctctgaaat ataggtttaa tttcaaatag aatatggact taaatgttaa tgagaaactg
2881 gctttaatca attctagcat tttattactg taatacaggg ctgatagagt gattttgtct
2941 tatatgagtc agttactact tacaggtgat aacttgcata ctattggaag ataaagttgt
3001 caaacttgtc aagaatgaga aaagccaaat tagaaaatcc tatgtcctag tttccttacc
3061 aaggataatt aaatatatca ctaagagctt tatatattga ttatatattg ttgacaactg
3121 gtttaagcat catagcctat gatgataaac actgcctata tatgtaaata gcttttcatc
3181 aattcttaaa tttcttaacc taggcttcag ggagcatatg aaaccaaaat tatatggaac
3241 attttctgtg tgtacatgta catgcatttt tctagggaga gagtccgtag gtttatcaga
3301 atatcaagga aaactgtgac ccaaagaagt ttaagaatca catacagtgc tgctggcttt
3361 ttgtgcttgg caaatgagtg acaatagaag aaataatttt tcttacacat tttaaaacgt
3421 tttctcttcc ttgtgattga agatgaaagg agtaagaaat taaggcattt gtttaattta
3481 tactggtaac ttatttaggg gggaggggac atgaaggtag gtaaataggt aggcctctaa
3541 ttgaaccacc tctctaagtt atgtacgtat atataagctg aaattgtgtt tgacattctg
3601 agggttttct ttttcttttt cctttttttt tttttttggt ggggggctgg gggtcagagt
3661 cttgttctgt tgcctgggct ggagtgcagt ggcatgatct cagctcactg caacctctgc
3721 cttctggatt caagtgattc tcctgcctca gcctcttgag tagctgggac tacaggtgcc
3781 cgccaccaca ccagctaatt tttgtatttt tagtagaggc gaagtttccc catgttggcc
3841 aggctggtct tgaactcccg acctcaagtg atctgtctac ctcggcctcc taaagtgctg
3901 agattacagg tgtgagccac cgtgcccggc ccattctaag ggttttcttt gaagacaggt
3961 caaatgctgt tagtaagttt caggagattg ttaattcctc agttatacca gattttataa
4021 aatatttgag aatagatggc taacaagagg ttagaaatac ttttccttaa ttttaatcca
4081 cagtatgtta catgcattct accactacat tttggtgcta tttaaggtgt gcaattttct
4141 ataggtgact tttgcaattc agggaagatt tgggcatatt aaatgaaaga atatctaatt
4201 gggggaggtg tgaagggaaa gaaattcttt tcaaaagctg accacaaaga gtagttaaaa
4261 gtttttgtca ctatcttcac aagtgtgtaa agcacagatt tcaacagagt gcttggcata
4321 ttgtagggtg ctcaatggtg gtttttatta ttattactca gattccacag tggcaagaaa
4381 catcattcta cataatggaa aacatttaca tcaaatccca cttactttaa tgcgaacttg
4441 gagataattt atggtattgt attgtaaacc attaatgaaa actttttcac agttgagtga
4501 aattaaaatc actatatctc
//