LOCUS AF151354 3446 bp mRNA linear HUM 22-OCT-2001
DEFINITION Homo sapiens general transcription factor 3 (GTF3) mRNA, complete
cds.
ACCESSION AF151354
VERSION AF151354.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3446)
AUTHORS Tassabehji,M., Carette,M., Wilmot,C., Donnai,D., Read,A.P. and
Metcalfe,K.
TITLE A transcription factor involved in skeletal muscle gene expression
is deleted in patients with Williams syndrome
JOURNAL Eur. J. Hum. Genet. 7 (7), 737-747 (1999)
PUBMED 10573005
REFERENCE 2 (bases 1 to 3446)
AUTHORS Tassabehji,M.
TITLE Direct Submission
JOURNAL Submitted (13-MAY-1999) Mediacl Genetics, St Mary's Hospital,
Hathersage Road, Manchester M13 OJH, UK
FEATURES Location/Qualifiers
source 1..3446
/db_xref="H-InvDB:HIT000071593"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="7"
/map="7q11.23"
gene 1..3446
/gene="GTF3"
CDS 394..3273
/gene="GTF3"
/codon_start=1
/product="general transcription factor 3"
/protein_id="AAF19786.1"
/translation="MALLGKRCDVPTNGCGPDRWNSAFTRKDEIITSLVSALDSMCSA
LSKLNAEVACVAVHDESAFVVGTEKGRMFLNARKELQSDFLRFCRGPPWKDPEAEHPK
KVQRGEGGGRSLPRSSLEHGSDVYLLRKMVEEVFDVLYSEALGRASVVPLPYERLLRE
PGLLAVQGLPEGLAFRRPAEYDPKALMAILEHSHRIRFKLKRPLEDGGRDSKALVELN
GVSLIPKGSRDCGLHGQAPKVPPQDLPPTATSSSMASFLYSTALPNHAIRELKQEAPS
CPLAPSDLGLSRPMPEPKATGAQDFSDCCGQKPTGPGGPLIQNVHASKRILFSIVHDK
SEKWDAFIKETEDINTLRECVQILFNSRYAEALGLDHMVPVPYRKIACDPEAVEIVGI
PDKIPFKRPCTYGVPKLKRILEERHSIHFIIKRMFDERIFTGNKFTKDTTKLEPASPP
EDTSAEVSRATVLDLAGNARSDKGSMSEDCGPGTSGELGGLRPIKIEPEDLDIIQVTV
PDPSPTSEEMTDSMPGHLPSEDSGYGMEMLTDKGLSEDARPEERPVEDSHGDVIRPLR
KQVELLFNTRYAKAIGISEPVKVPYSKFLMHPEELFVVGLPEGISLRRPNCFGIAKLR
KILEASNSIQFVIKRPELLTEGVKEPIMDSQGTASSLGFSPPALPPERDSGDPLVDES
LKRQGFQENYDARLSRIDIANTLREQVQDLFNKKYGEALGIKYPVQVPYKRIKSNPGS
VIIEGLPPGIPFRKPCTFGSQNLERILAVADKIKFTVTRPFQGLIPKPDEDDANRLGE
KVILREQVKELFNEKYGEALGLNRPVLVPYKLIRDSPDAVEVTGLPDDIPFRNPNTYD
IHRLEKILKAREHVRMVIINQLQPFAEICNDAKVPAKDSSIPKRKRKRVSEGNSVSSS
SSSSSSSSSNPDSVASANQISLVQWPMYMVDYAGLNVQLPGPLNY"
BASE COUNT 757 a 1074 c 984 g 631 t
ORIGIN
1 taaatggcag ccaatggagg gtggtgttgc gcggggctgg gattagggcc ggggcgaatg
61 gctggcaatc ttactgggat tacagaacaa agagcctccc cgcgctcccg ctctccgctc
121 ctctccccgc gccgccccgc cctccgccgc agcccgcgcc gggggtgggg gccgccgagc
181 gccagccccc cggccggccg attccccccc cgcgccccct ccccgcgcct ccctccccgc
241 cctcgccgcg ccgccgtcct cgcctccctc tgcctctcct tcccccattc tcccggatta
301 attaaggagg cagcggcagg aggctgagtc ctggccgcgg gccggggccg gggcgccgct
361 ggcaggagcg cttggggatc ctccaaggcg accatggcct tgctgggtaa gcgctgtgac
421 gtccccacca acggctgcgg acccgaccgc tggaactccg cgttcacccg caaagacgag
481 atcatcacca gcctcgtgtc tgccttagac tccatgtgct cagcgctgtc caaactgaac
541 gccgaggtgg cctgtgtcgc cgtgcacgat gagagcgcct ttgtggtggg cacagagaag
601 gggagaatgt tcctgaatgc ccggaaggag ctacagtcag acttcctcag gttctgccga
661 gggcccccgt ggaaggatcc ggaggcagag caccccaaga aggtgcagcg gggcgagggt
721 ggaggccgta gcctccctcg gtcctccctg gaacatggct cagatgtgta ccttctgcgg
781 aagatggtag aggaggtgtt tgatgttctt tatagcgagg ccctgggaag ggccagtgtg
841 gtgccactgc cctatgagag gctgctcagg gagccagggc tgctggccgt gcaggggctg
901 cccgaaggcc tggccttccg aaggccagcc gagtatgacc ccaaggccct catggccatc
961 ctggaacaca gccaccgcat ccgcttcaag ctcaagaggc cacttgagga tggcgggcgg
1021 gactcgaagg ccctggtgga gctgaacggt gtctccctga ttcccaaggg gtcacgggac
1081 tgtggcctgc atggccaggc ccccaaggtg ccaccccagg acctgccccc aaccgccacc
1141 tcctcctcca tggccagctt cctgtacagc acggcgctcc ccaaccacgc catccgagag
1201 ctcaagcagg aagcaccttc ctgccccctt gcccccagcg acctgggcct gagtcggccc
1261 atgccagagc ccaaggccac cggtgcccaa gacttctccg actgttgtgg acagaagccc
1321 actgggcctg gtgggcctct catccagaac gtccatgcct ccaagcgcat tctcttctcc
1381 atcgtccatg acaagtcaga gaagtgggac gccttcataa aggaaaccga ggacatcaac
1441 acgctccggg agtgtgtgca gatcctgttt aacagcagat atgcggaagc cctgggcctg
1501 gaccacatgg tccccgtgcc ctaccggaag attgcctgtg acccggaggc tgtggagatc
1561 gtgggcatcc cggacaagat ccccttcaag cgcccctgca cttatggagt ccccaagctg
1621 aagcggatcc tggaggagcg ccatagtatc cacttcatca ttaagaggat gtttgatgag
1681 cgaattttca cagggaacaa gtttaccaaa gacaccacga agctggagcc agccagcccg
1741 ccagaggaca cctctgcaga ggtctctagg gccaccgtcc ttgaccttgc tgggaatgct
1801 cggtcagaca agggcagcat gtctgaagac tgtgggccag gaacctccgg ggagctgggc
1861 gggctgaggc cgatcaaaat tgagccagag gatctggaca tcattcaggt caccgtccca
1921 gacccctcgc caacctctga ggaaatgaca gactcgatgc ctgggcacct gccatcggag
1981 gattctggtt atgggatgga gatgctgaca gacaaaggtc tgagtgagga cgcgcggccg
2041 gaggagaggc ccgtggagga cagccacggt gacgtgatcc ggcccctgcg gaagcaggtg
2101 gagctgctct tcaacacacg atacgccaag gccattggca tctcggagcc cgtcaaggtg
2161 ccgtactcca agtttctgat gcacccggag gagctgtttg tggtgggact gcctgaaggc
2221 atctccctcc gcaggcccaa ctgcttcggg atcgccaagc tccggaagat tctggaggcc
2281 agcaacagca tccagtttgt catcaagagg cccgagctgc tcactgaggg agtcaaagag
2341 cccatcatgg atagtcaagg aactgcctcc tcacttggct tctctccccc tgccctgccc
2401 ccagagaggg attccgggga ccctctggtg gacgagagcc tgaagagaca gggctttcaa
2461 gaaaattatg acgcgaggct ctcacggatc gacatcgcca acacactaag ggagcaggtc
2521 caggaccttt tcaataagaa atacggggaa gccttgggca tcaagtaccc ggtccaggtc
2581 ccctacaagc ggatcaagag taaccccggc tccgtgatca tcgaggggct gcccccagga
2641 atcccgttcc gaaagccctg taccttcggc tcccagaacc tggagaggat tcttgctgtg
2701 gctgacaaga tcaagttcac agtcaccagg cctttccaag gactcatccc aaagcctgat
2761 gaagatgacg ccaacagact cggggagaag gtgatcctgc gggagcaggt gaaggaactc
2821 ttcaacgaga aatacggtga ggccctgggc ctgaaccggc cggtgctggt cccttataaa
2881 ctaatccggg acagcccaga cgccgtggag gtcacgggtc tgcctgatga catccccttc
2941 cggaacccca acacgtacga catccaccgg ctggagaaga tcctgaaggc ccgagagcat
3001 gtccgcatgg tcatcattaa ccagctccaa ccctttgcag aaatctgcaa tgatgccaag
3061 gtgccagcca aagacagcag cattcccaag cgcaagagaa agcgggtctc ggaaggaaat
3121 tccgtctcct cttcctcctc gtcttcctct tcctcgtcct ctaacccgga ttcagtggca
3181 tcggccaacc agatctcact cgtgcaatgg ccaatgtaca tggtggacta tgccggcctg
3241 aacgtgcagc tcccgggacc tcttaattac tagacctcag tactgaatca ggacctcact
3301 cagaaagact aaaggaaatg taatttatgt acaaaatgta tattcggata tgtatcgatg
3361 ccttttagtt tttccaatga tttttacact atattcctgc caccaaggcc tttttaaata
3421 agtaaaaaaa aaaaaaaaaa aaaaaa
//