LOCUS AF151105 1821 bp mRNA linear HUM 17-DEC-2001
DEFINITION Homo sapiens 3'-5' exonuclease TREX1 mRNA, complete cds.
ACCESSION AF151105
VERSION AF151105.3
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1821)
AUTHORS Mazur,D.J. and Perrino,F.W.
TITLE Identification and expression of the TREX1 and TREX2 cDNA sequences
encoding mammalian 3'-->5' exonucleases
JOURNAL J. Biol. Chem. 274 (28), 19655-19660 (1999)
PUBMED 10391904
REFERENCE 2 (bases 1 to 1821)
AUTHORS Perrino,F.W. and Mazur,D.J.
TITLE Direct Submission
JOURNAL Submitted (13-MAY-1999) Department of Biochemistry, Wake Forest
University School of Medicine, Medical Center Blvd., Winston Salem,
NC 27157, USA
REFERENCE 3 (bases 1 to 1821)
AUTHORS Perrino,F.W. and Mazur,D.J.
TITLE Direct Submission
JOURNAL Submitted (19-AUG-1999) Department of Biochemistry, Wake Forest
University School of Medicine, Medical Center Blvd., Winston Salem,
NC 27157, USA
REMARK Sequence update by submitter
REFERENCE 4 (bases 1 to 1821)
AUTHORS Perrino,F.W. and Mazur,D.J.
TITLE Direct Submission
JOURNAL Submitted (03-NOV-2000) Department of Biochemistry, Wake Forest
University School of Medicine, Medical Center Blvd., Winston Salem,
NC 27157, USA
REMARK Sequence update by submitter
COMMENT On Dec 17, 2001 this sequence version replaced AF151105.2.
FEATURES Location/Qualifiers
source 1..1821
/db_xref="H-InvDB:HIT000071589"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/note="derived from EST W24304"
CDS 794..1738
/codon_start=1
/product="3'-5' exonuclease TREX1"
/protein_id="AAD48774.2"
/translation="MGSQALPPGPMQTLIFFDMEATGLPFSQPKVTELCLLAVHRCAL
ESPPTSQGPPPTVPPPPRVVDKLSLCVAPGKACSPAASEITGLSTAVLAAHGRQCFDD
NLANLLLAFLRRQPQPWCLVAHNGDRYDFPLLQAELAMLGLTSALDGAFCVDSITALK
ALERASSPSEHGPRKSYSLGSIYTRLYGQSPPDSHTAEGDVLALLSICQWRPQALLRW
VDAHARPFGTIRPMYGVTASARTKPRPSAVTTTAHLATTRNTSPSLGESRGTKDLPPV
KDPGALSREGLLAPLGLLAILTLAVATLYGLSLATPGE"
BASE COUNT 387 a 582 c 541 g 311 t
ORIGIN
1 ccattgtgtg gcagggaagg aggtggctct tggcccaggc ctaaaccagg aaagcctggg
61 aaactgggac ccacaggtgg gcatgaaagg gccgcagcag gggctcccag cagtgtgtaa
121 gaccgggagc tggtctggca ccactgccct ggtccttcca gctgcctgtc actggtatga
181 tggccccggt gcattgtgcc accagcaggc cacagctgtg gatcttggaa ggcctctggg
241 gtcccccggg agcaggggag tgggtgtggg ggggaacgga tggtggtgag agggacagac
301 caggcaggct gacgagcagg gcgggcctgg ctcacgtggg cctgtaggcg ggcccacgcc
361 aagtttcact taccgccact gctgccagcg agagccgcgg gagagtgtgc agccgagtca
421 ctactgcctg cctgcctgcc tgctacggtg agtgtggccc ccacaatggg atggcgcagg
481 gcaggagggc catgggttcc cccaccccag actaaggggg cactagggga ggggccgagt
541 catgtgaaga gggagaccct ctcagacagt cgaatgtgct ggtcccacta aggaaaccac
601 ctcaccctct ccaacttcct gcctgaaaat gggccctgga gctcgcagac agggcaggat
661 tgtgcaggga aggcctgaga tgtgcttctg cccaccccct accccactcc ctccccttcg
721 gatcttaaca ctgggcactc acacacccac cccatgctcc tctccaggct cagcagcagg
781 tacgtaccca accatgggct cgcaggccct gcccccgggg cccatgcaga ccctcatctt
841 tttcgacatg gaggccactg gcttgccctt ctcccagccc aaggtcacgg agctgtgcct
901 gctggctgtc cacagatgtg ccctggagag cccccccacc tctcaggggc cacctcccac
961 agttcctcca ccaccgcgtg tggtagacaa gctctccctg tgtgtggctc cggggaaggc
1021 ctgcagccct gcagccagcg agatcacagg tctgagcaca gctgtgctgg cagcgcatgg
1081 gcgtcaatgt tttgatgaca acctggccaa cctgctccta gccttcctgc ggcgccagcc
1141 acagccctgg tgcctggtgg cacacaatgg tgaccgctac gacttccccc tgctccaagc
1201 agagctggct atgctgggcc tcaccagtgc tctggatggt gccttctgtg tggatagcat
1261 cactgcgctg aaggccctgg agcgagcaag cagcccctca gaacacggcc caaggaagag
1321 ctacagccta ggcagcatct acactcgcct gtatgggcag tcccctccag actcgcacac
1381 ggctgagggt gatgtcctgg ccctgctcag catctgtcag tggagaccac aggccctgct
1441 gcggtgggtg gatgctcacg ccaggccttt cggcaccatc aggcccatgt atggggtcac
1501 agcctctgct aggaccaagc caagaccatc tgctgtcaca accactgcac acctggccac
1561 aaccaggaac actagtccca gccttggaga gagcaggggt accaaggatc ttcctccagt
1621 gaaggaccct ggagccctat ccagggaggg gctgctggcc ccactgggtc tgctggccat
1681 cctgaccttg gcagtagcca cactgtatgg actatccctg gccacacctg gggagtaggc
1741 caagaaggaa aatctgacga ataaagaccc ccgctgcccc ataaaaaaaa aaaaaaaaaa
1801 aaaaaaaaaa aaaaaaaaaa a
//