LOCUS AF148537 4632 bp mRNA linear HUM 09-SEP-2000
DEFINITION Homo sapiens reticulon 4a mRNA, complete cds.
ACCESSION AF148537
VERSION AF148537.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4632)
AUTHORS Yang,J., Yu,L., Bi,A.D. and Zhao,S.Y.
TITLE Assignment of the human reticulon 4 gene (RTN4) to chromosome
2p14-->2p13 by radiation hybrid mapping
JOURNAL Cytogenet. Cell Genet. 88 (1-2), 101-102 (2000)
PUBMED 10773680
REFERENCE 2 (bases 1 to 4632)
AUTHORS Zhou,Y., Yu,L. and Zhao,S.Y.
TITLE Direct Submission
JOURNAL Submitted (05-MAY-1999) Lab of Human Gene Research, Institute of
Genetics, Fudan University, No. 220 Handan Rd., Shanghai 200433,
P.R.China
FEATURES Location/Qualifiers
source 1..4632
/db_xref="H-InvDB:HIT000071539"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
CDS 142..3720
/note="RTN4a"
/codon_start=1
/product="reticulon 4a"
/protein_id="AAG12176.1"
/translation="MEDLDQSPLVSSSDSPPRPQPAFKYQFVREPEDEEEEEEEEEED
EDEDLEELEVLERKPAAGLSAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAP
ERQPSWDPSPVSSTVPAPSPLSAAAVSPSKLPEDDEPPARPPPPPPASVSPQAEPVWT
PPAPAPAAPPSTPAAPKRRGSSGSVDETLFALPAASEPVIRSSAENMDLKEQPGNTIS
AGQEDFPSVLLETAASLPSLSPLSAASFKEHEYLGNLSTVLPTEGTLQENVSEASKEV
SEKAKTLLIDRDLTEFSELEYSEMGSSFSVSPKAESAVIVANPREEIIVKNKDEEEKL
VSNNILHNQQELPTALTKLVKEDEVVSSEKAKDSFNEKRVAVEAPMREEYADFKPFER
VWEVKDSKEDSDMLAAGGKIESNLESKVDKKCFADSLEQTNHEKDSESSNDDTSFPST
PEGIKDRSGAYITCAPFNPAATESIATNIFPLLGDPTSENKTDEKKIEEKKAQIVTEK
NTSTKTSNPFLVAAQDSETDYVTTDNLTKVTEEVVANMPEGLTPDLVQEACESELNEV
TGTKIAYETKMDLVQTSEVMQESLYPAAQLCPSFEESEATPSPVLPDIVMEAPLNSAV
PSAGASVIQPSSSPLEASSVNYESIKHEPENPPPYEEAMSVSLKKVSGIKEEIKEPEN
INAALQETEAPYISIACDLIKETKLSAEPAPDFSDYSEMAKVEQPVPDHSELVEDSSP
DSEPVDLFSDDSIPDVPQKQDETVMLVKESLTETSFESMIEYENKEKLSALPPEGGKP
YLESFKLSLDNTKDTLLPDEVSTLSKKEKIPLQMEELSTAVYSNDDLFISKEAQIRET
ETFSDSSPIEIIDEFPTLISSKTDSFSKLAREYTDLEVSHKSEIANAPDGAGSLPCTE
LPHDLSLKNIQPKVEEKISFSDDFSKNGSATSKVLLLPPDVSALATQAEIESIVKPKV
LVKEAEKKLPSDTEKEDRSPSAIFSAELSKTSVVDLLYWRDIKKTGVVFGASLFLLLS
LTVFSIVSVTAYIALALLSVTISFRIYKGVIQAIQKSDEGHPFRAYLESEVAISEELV
QKYSNSALGHVNCTIKELRRLFLVDDLVDSLKFAVLMWVFTYVGALFNGLTLLILALI
SLFSVPVIYERHQAQIDHYLGLANKNVKDAMAKIQAKIPGLKRKAE"
regulatory 4605..4610
/regulatory_class="polyA_signal_sequence"
polyA_site 4622
BASE COUNT 1398 a 1013 c 1011 g 1210 t
ORIGIN
1 gagccgtcac cacagtaggt ccctcggctc agtcggccca gcccctctca gtcctcccca
61 acccccacaa ccgcccgcgg ctctgagacg cggccccggc ggcggcggca gcagctgcag
121 catcatctcc accctccagc catggaagac ctggaccagt ctcctctggt ctcgtcctcg
181 gacagcccac cccggccgca gcccgcgttc aagtaccagt tcgtgaggga gcccgaggac
241 gaggaggaag aagaggagga ggaagaggag gacgaggacg aagacctgga ggagctggag
301 gtgctggaga ggaagcccgc cgccgggctg tccgcggccc cagtgcccac cgcccctgcc
361 gccggcgcgc ccctgatgga cttcggaaat gacttcgtgc cgccggcgcc ccggggaccc
421 ctgccggccg ctccccccgt cgccccggag cggcagccgt cttgggaccc gagcccggtg
481 tcgtcgaccg tgcccgcgcc atccccgctg tctgctgccg cagtctcgcc ctccaagctc
541 cctgaggacg acgagcctcc ggcccggcct ccccctcctc ccccggccag cgtgagcccc
601 caggcagagc ccgtgtggac cccgccagcc ccggctcccg ccgcgccccc ctccaccccg
661 gccgcgccca agcgcagggg ctcctcgggc tcagtggatg agaccctttt tgctcttcct
721 gctgcatctg agcctgtgat acgctcctct gcagaaaata tggacttgaa ggagcagcca
781 ggtaacacta tttcggctgg tcaagaggat ttcccatctg tcctgcttga aactgctgct
841 tctcttcctt ctctgtctcc tctctcagcc gcttctttca aagaacatga ataccttggt
901 aatttgtcaa cagtattacc cactgaagga acacttcaag aaaatgtcag tgaagcttct
961 aaagaggtct cagagaaggc aaaaactcta ctcatagata gagatttaac agagttttca
1021 gaattagaat actcagaaat gggatcatcg ttcagtgtct ctccaaaagc agaatctgcc
1081 gtaatagtag caaatcctag ggaagaaata atcgtgaaaa ataaagatga agaagagaag
1141 ttagttagta ataacatcct tcataatcaa caagagttac ctacagctct tactaaattg
1201 gttaaagagg atgaagttgt gtcttcagaa aaagcaaaag acagttttaa tgaaaagaga
1261 gttgcagtgg aagctcctat gagggaggaa tatgcagact tcaaaccatt tgagcgagta
1321 tgggaagtga aagatagtaa ggaagatagt gatatgttgg ctgctggagg taaaatcgag
1381 agcaacttgg aaagtaaagt ggataaaaaa tgttttgcag atagccttga gcaaactaat
1441 cacgaaaaag atagtgagag tagtaatgat gatacttctt tccccagtac gccagaaggt
1501 ataaaggatc gttcaggagc atatatcaca tgtgctccct ttaacccagc agcaactgag
1561 agcattgcaa caaacatttt tcctttgtta ggagatccta cttcagaaaa taagaccgat
1621 gaaaaaaaaa tagaagaaaa gaaggcccaa atagtaacag agaagaatac tagcaccaaa
1681 acatcaaacc cttttcttgt agcagcacag gattctgaga cagattatgt cacaacagat
1741 aatttaacaa aggtgactga ggaagtcgtg gcaaacatgc ctgaaggcct gactccagat
1801 ttagtacagg aagcatgtga aagtgaattg aatgaagtta ctggtacaaa gattgcttat
1861 gaaacaaaaa tggacttggt tcaaacatca gaagttatgc aagagtcact ctatcctgca
1921 gcacagcttt gcccatcatt tgaagagtca gaagctactc cttcaccagt tttgcctgac
1981 attgttatgg aagcaccatt gaattctgca gttcctagtg ctggtgcttc cgtgatacag
2041 cccagctcat caccattaga agcttcttca gttaattatg aaagcataaa acatgagcct
2101 gaaaaccccc caccatatga agaggccatg agtgtatcac taaaaaaagt atcaggaata
2161 aaggaagaaa ttaaagagcc tgaaaatatt aatgcagctc ttcaagaaac agaagctcct
2221 tatatatcta ttgcatgtga tttaattaaa gaaacaaagc tttctgctga accagctccg
2281 gatttctctg attattcaga aatggcaaaa gttgaacagc cagtgcctga tcattctgag
2341 ctagttgaag attcctcacc tgattctgaa ccagttgact tatttagtga tgattcaata
2401 cctgacgttc cacaaaaaca agatgaaact gtgatgcttg tgaaagaaag tctcactgag
2461 acttcatttg agtcaatgat agaatatgaa aataaggaaa aactcagtgc tttgccacct
2521 gagggaggaa agccatattt ggaatctttt aagctcagtt tagataacac aaaagatacc
2581 ctgttacctg atgaagtttc aacattgagc aaaaaggaga aaattccttt gcagatggag
2641 gagctcagta ctgcagttta ttcaaatgat gacttattta tttctaagga agcacagata
2701 agagaaactg aaacgttttc agattcatct ccaattgaaa ttatagatga gttccctaca
2761 ttgatcagtt ctaaaactga ttcattttct aaattagcca gggaatatac tgacctagaa
2821 gtatcccaca aaagtgaaat tgctaatgcc ccggatggag ctgggtcatt gccttgcaca
2881 gaattgcccc atgacctttc tttgaagaac atacaaccca aagttgaaga gaaaatcagt
2941 ttctcagatg acttttctaa aaatgggtct gctacatcaa aggtgctctt attgcctcca
3001 gatgtttctg ctttggccac tcaagcagag atagagagca tagttaaacc caaagttctt
3061 gtgaaagaag ctgagaaaaa acttccttcc gatacagaaa aagaggacag atcaccatct
3121 gctatatttt cagcagagct gagtaaaact tcagttgttg acctcctgta ctggagagac
3181 attaagaaga ctggagtggt gtttggtgcc agcctattcc tgctgctttc attgacagta
3241 ttcagcattg tgagcgtaac agcctacatt gccttggccc tgctctctgt gaccatcagc
3301 tttaggatat acaagggtgt gatccaagct atccagaaat cagatgaagg ccacccattc
3361 agggcatatc tggaatctga agttgctata tctgaggagt tggttcagaa gtacagtaat
3421 tctgctcttg gtcatgtgaa ctgcacgata aaggaactca ggcgcctctt cttagttgat
3481 gatttagttg attctctgaa gtttgcagtg ttgatgtggg tatttaccta tgttggtgcc
3541 ttgtttaatg gtctgacact actgattttg gctctcattt cactcttcag tgttcctgtt
3601 atttatgaac ggcatcaggc acagatagat cattatctag gacttgcaaa taagaatgtt
3661 aaagatgcta tggctaaaat ccaagcaaaa atccctggat tgaagcgcaa agctgaatga
3721 aaacgcccaa aataattagt aggagttcat ctttaaaggg gatattcatt tgattatacg
3781 gatctttatt tttagccatg cactgttgtg aggaaaaatt acctgtcttg actgccatgt
3841 gttcatcatc ttaagtattg taagctgcta tgtatggatt taaaccgtaa tcatatcttt
3901 ttcctatctg aggcactggt ggaataaaaa acctgtatat tttactttgt tgcagatagt
3961 cttgccgcat cttggcaagt tgcagagatg gtggagctag aaaaaaaaaa aaaaaagccc
4021 ttttcagttt gtgcactgtg tatggtccgt gtagattgat gcagattttc tgaaatgaaa
4081 tgtttgttta gacgagatca taccggtaaa gcaggaatga caaagcttgc ttttctggta
4141 tgttctaggt gtattgtgac ttttactgtt atattaattg ccaatataag taaatataga
4201 ttatatatgt atagtgtttc acaaagctta gacctttacc ttccagccac cccacagtgc
4261 ttgatatttc agagtcagtc attggttata catgtgtagt tccaaagcac ataagctaga
4321 agaagaaata tttctaggag cactaccatc tgttttcaac atgaaatgcc acacacatag
4381 aactccaaca acatcaattt cattgcacag actgactgta gttaattttg tcacagaatc
4441 tatggactga atctaatgct tccaaaaatg ttgtttgttt gcaaatatca aacattgtta
4501 tgcaagaaat tattaattac aaaatgaaga tttataccat tgtggtttaa gctgtactga
4561 actaaatctg tggaatgcat tgtgaactgt aaaagcaaag tatcaataaa gcttatagac
4621 ttaaaaaaaa aa
//