LOCUS AF145442 2667 bp mRNA linear HUM 24-MAY-2000
DEFINITION Homo sapiens leukolysin mRNA, complete cds.
ACCESSION AF145442
VERSION AF145442.2
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2667)
AUTHORS Pei,D.
TITLE Leukolysin/MMP25/MT6-MMP: a novel matrix metalloproteinase
specifically expressed in the leukocyte lineage
JOURNAL Cell Res. 9 (4), 291-303 (1999)
PUBMED 10628838
REFERENCE 2 (bases 1 to 2667)
AUTHORS Pei,D.Q.
TITLE Direct Submission
JOURNAL Submitted (24-APR-1999) Pharmacology, Univ. of Minnesota, 3-249
Millard Hall, 435 Delaware St., Minneapolis, MN 55455, USA
REFERENCE 3 (bases 1 to 2667)
AUTHORS Pei,D.Q.
TITLE Direct Submission
JOURNAL Submitted (24-MAY-2000) Pharmacology, Univ. of Minnesota, 3-249
Millard Hall, 435 Delaware St., Minneapolis, MN 55455, USA
REMARK Sequence update by submitter
COMMENT On May 24, 2000 this sequence version replaced AF145442.1.
FEATURES Location/Qualifiers
source 1..2667
/db_xref="H-InvDB:HIT000071313"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_type="leukocyte"
CDS 25..1713
/note="MT6-MMP; matrix metalloproteinase"
/codon_start=1
/product="leukolysin"
/protein_id="AAF66697.2"
/translation="MRLRLRLLALLLLLLAPPARAPKPSAQDVSLGVDWLTRYGYLPP
PHPAQAQLQSPEKLRDAIKVMQRFAGLPETGRMDPGTVATMRKPRCSLPDVLGVAGLV
RRRRRYALSGSVWKKRTLTWRVRSFPQSSQLSQETVRVLMSYALMAWGMESGLTFHEV
DSPQGQEPDILIDFARAFHQDSYPFDGLGGTLAHAFFPGEHPISGDTHFDDEETWTFG
SKDGEGTDLFAVAVHEFGHALGLGHSSAPNSIMRPFYQGPVGDPDKYRLSQDDRDGLQ
QLYGKAPQTPYDKPTRKPLAPPPQPPASPTHSPSFPIPDRCEGNFDAIANIRGETFFF
KGPWFWRLQPSGQLVSPRPARLHRFWEGLPAQVRVVQAAYARHRDGRILLFSGPQFWV
FQDRQLEGGARPLTELGLPPGEEVDAVFSWPQNGKTYLVRGRQYWRYDEAAARPDPGY
PRDLSLWEGAPPSPDDVTVSNAGDTYFFKGAHYWRFPKNSIKTEPDAPQPMGPNWLDC
PAPSSGPRAPRPPKATPVSETCDCQCELNQAAGRWPAPIPLLLLPLLVGGVASR"
BASE COUNT 412 a 991 c 831 g 433 t
ORIGIN
1 cggcggcccg ggctggggcg caccatgcgg ctgcggctcc ggcttctggc gctgctgctt
61 ctgctgctgg caccgcccgc gcgcgccccg aagccctcgg cgcaggacgt gagcctgggc
121 gtggactggc tgactcgcta tggttacctg ccgccacccc accctgccca ggcccagctg
181 cagagccctg agaagttgcg cgatgccatc aaagtcatgc agaggttcgc ggggctgccg
241 gagaccggcc gcatggaccc agggacagtg gccaccatgc gtaagccccg ctgctccctg
301 cctgacgtgc tgggggtggc ggggctggtc aggcggcgtc gccggtacgc tctgagcggc
361 agcgtgtgga agaagcgaac cctgacatgg agggtacgtt ccttccccca gagctcccag
421 ctgagccagg agaccgtgcg ggtcctcatg agctatgccc tgatggcctg gggcatggag
481 tcaggcctca catttcatga ggtggattcc ccccagggcc aggagcccga catcctcatc
541 gactttgccc gcgccttcca ccaggacagc taccccttcg acgggttggg gggcacccta
601 gcccatgcct tcttccctgg ggagcacccc atctccgggg acactcactt tgacgatgag
661 gagacctgga cttttgggtc aaaagacggc gaggggaccg acctgtttgc cgtggctgtc
721 catgagtttg gccacgccct gggcctgggc cactcctcag cccccaactc cattatgagg
781 cccttctacc agggtccggt gggcgaccct gacaagtacc gcctgtctca ggatgaccgc
841 gatggcctgc agcaactcta tgggaaggcg ccccaaaccc catatgacaa gcccacaagg
901 aaacccctgg ctcctccgcc ccagcccccg gcctcgccca cacacagccc atccttcccc
961 atccctgatc gatgtgaggg caattttgac gccatcgcca acatccgagg ggaaactttc
1021 ttcttcaaag gcccctggtt ctggcgcctc cagccctccg gacagctggt gtccccgcga
1081 cccgcacggc tgcaccgctt ctgggagggg ctgcccgccc aagtgagggt ggtgcaggcc
1141 gcctatgctc ggcaccgaga cggccgaatc ctcctcttta gcgggcccca gttctgggtg
1201 ttccaggacc ggcagctgga gggcggggcg cggccgctca cggagctggg gctgcccccg
1261 ggagaggagg tggacgccgt gttctcgtgg ccacagaacg ggaagaccta cctggtccgc
1321 ggccggcagt actggcgcta cgacgaggcg gcggcgcgcc cggaccccgg ctaccctcgc
1381 gacctgagcc tctgggaagg cgcgcccccc tcccctgacg atgtcaccgt cagcaacgca
1441 ggtgacacct acttcttcaa gggcgcccac tactggcgct tccccaagaa cagcatcaag
1501 accgagccgg acgcccccca gcccatgggg cccaactggc tggactgccc cgccccgagc
1561 tctggtcccc gcgcccccag gccccccaaa gcgacccccg tgtccgaaac ctgcgattgt
1621 cagtgcgagc tcaaccaggc cgcaggacgt tggcctgctc ccatcccgct gctcctcttg
1681 cccctgctgg tggggggtgt agcctcccgc tgatgggggg agccatccag accgaacagc
1741 gccctccacg gccgagtccc ccgccgctgg acctggtcgg gggttgtgag gcgctgcgga
1801 ggccccttgt ctgttcccac ggacgggggc tcgggcgcgg actaagcagg ggggatctcc
1861 cgcgcagggg cggcggcggc ggggaccggt cgcctggcgc tgggctcagt ctcctcaggg
1921 tctgagaccc cggcgctgcc accggaaccc gccttcaggg gcgcacgcgc gctgggacca
1981 tgcgtcggtc gtcgcccccg tcgttccctc ccggctgccg ccagggggcg gtcggacccc
2041 gcctcccgag cccggggagg ggcggggagg acaaggggcg ggcccgcggc ctcacccgga
2101 gggacggcag ccccggtcgc gcgctggccc cgcaggacct tccttttcca ggaagagcca
2161 gcttttctcg gagcgcagtc ctgggactct ccgcagcccc gccccgcctg gccactgcgt
2221 ctggcattcc tgggtcgtta gaggacaggc ctgactgcga agctgtgcct tgcccctctc
2281 ccacccgcag tttctcaccc cgttctgctc ccacaaggcc cccctacagt cactgccaca
2341 ctggtgggga cctgggaccc agacccggaa ccagcccaga tatcacccct gaggacccat
2401 gcgccacgtc ctgggtggtg gaatcagtgg ctggagggac gacccttgct ctccaggctg
2461 ttaacctttt ccgttgctcc cccgccaccc acctcctcct ccccaggcca cccagcttgg
2521 gcacctccct gggcccagaa ctgccttcca ttcaatgggg aacccttcta tccccaagaa
2581 ccccttccct gcttgcaccc tggagagaac agcttgactc ccatcaactc aacgctggtg
2641 gaaagacagg gaccgaaccc tggctca
//