LOCUS AF142567 6990 bp mRNA linear HUM 20-MAR-2000
DEFINITION Homo sapiens T calcium channel alpha1I subunit, delta36B splice
variant (CACNA1I) mRNA, complete cds.
ACCESSION AF142567
VERSION AF142567.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 6990)
AUTHORS Mittman,S., Guo,J. and Agnew,W.S.
TITLE Alternative Splicing of CACNA1I Yields Calcium Channel Alpha1I
Isoforms With Distinct C Termini
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 6990)
AUTHORS Mittman,S., Guo,J. and Agnew,W.S.
TITLE Direct Submission
JOURNAL Submitted (13-APR-1999) Anesthesiology/Critical Care Medicine, The
Johns Hopkins University School of Medicine, 600 N. Wolfe Street,
Meyer 297, Baltimore, MD 21287-7294, USA
FEATURES Location/Qualifiers
source 1..6990
/db_xref="H-InvDB:HIT000071211"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="22"
/map="22q12.3-13.2"
gene 1..6990
/gene="CACNA1I"
CDS 1..6672
/gene="CACNA1I"
/note="low-voltage-activated calcium channel"
/codon_start=1
/product="T calcium channel alpha1I subunit, delta36B
splice variant"
/protein_id="AAF25722.1"
/translation="MAESASPPSSSAAAPAAEPGVTTEQPGPRSPPSSPPGLEEPLDG
ADPHVPHPDLAPIAFFCLRQTTSPRNWCIKMVCNPWFECVSMLVILLNCVTLGMYQPC
DDMDCLSDRCKILQVFDDFIFIFFAMEMVLKMVALGIFGKKCYLGDTWNRLDFFIVMA
GMVEYSLDLQNINLSAIRTVRVLRPLKAINRVPSMRILVNLLLDTLPMLGNVLLLCFF
VFFIFGIIGVQLWAGLLRNRCFLEENFTIQGDVALPPYYQPEEDDEMPFICSLSGDNG
IMGCHEIPPLKEQGRECCLSKDDVYDFGAGRQDLNASGLCVNWNRYYNVCRTGSANPH
KGAINFDNIGYAWIVIFQVITLEGWVEIMYYVMDAHSFYNFIYFILLIIVGSFFMINL
CLVVIATQFSETKQREHRLMLEQRQRYLSSSTVASYAEPGDCYEEIFQYVCHILRKAK
RRALGLYQALQSRRQALGPEAPAPAKPGPHAKEPRHYHGKTKGQGDEGRHLGSRHCQT
LHGPASPGNDHSGRELCPQHSPLDATPHTLVQPIPATLASDPASCPCCQHEDGRRPSG
LGSTDSGQEGSGSGSSAGGEDEADGDGARSSEDGASSELGKEEEEEEQADGAVWLCGD
VWRETRAKLRGIVDSKYFNRGIMMAILVNTVSMGIEHHEQPEELTNILEICNVVFTSM
FALEMILKLAAFGLFDYLRNPYNIFDSIIVIISIWEIVGQADGGLSVLRTFRLLRVLK
LVRFMPALRRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHIFGCKFSLRTDTGDTV
PDRKNFDSLLWAIVTVFQILTQEDWNVVLYNGMASTSPWASLYFVALMTFGNYVLFNL
LVAILVEGFQAEGDANRSYSDEDQSSSNIEEFDKLQEGLDSSGDPKLCPIPMTPNGHL
DPSLPLGGHLGPAGAAGPAPRLSLQPDPMLVALGSRKSSVMSLGRMSYDQRSLSSSRS
SYYGPWGRSAAWASRRSSWNSLKHKPPSAEHESLLSAERGGGARVCEVAADEGPPRAA
PLHTPHAHHIHHGPHLAHRHRHHRRTLSLDNRDSVDLAELVPAVGAHPRAAWRAAGPA
PGHEDCNGRMPSIAKDVFTKMGDRGDRGEDEEEIDYTLCFRVRKMIDVYKPDWCEVRE
DWSVYLFSPENRFRVLCQTIIAHKLFDYVVLAFIFLNCITIALERPQIEAGSTERIFL
TVSNYIFTAIFVGEMTLKVVSLGLYFGEQAYLRSSWNVLDGFLVFVSIIDIVVSLASA
GGAKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLISSLKPIGNIVLICCAFFIIF
GILGVQLFKGKFYHCLGVDTRNITNRSDCMAANYRWVHHKYNFDNLGQALMSLFVLAS
KDGWVNIMYNGLDAVAVDQQPVTNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHK
CRQHQEAEEARRREEKRLRRLEKKRRKAQRLPYYATYCHTRLLIHSMCTSHYLDIFIT
FIICLNVVTMSLEHYNQPTSLETALKYCNYMFTTVFVLEAVLKLVAFGLRRFFKDRWN
QLDLAIVLLSVMGITLEEIEINAALPINPTIIRIMRVLRIARVLKLLKMATGMRALLD
TVVQALPQVGNLGLLFMLLFFIYAALGVELFGKLVCNDENPCEGMSRHATFENFGMAF
LTLFQVSTGDNWNGIMKDTLRDCTHDERSCLSSLQFVSPLYFVSFVLTAQFVLINVVV
AVLMKHLDDSNKEAQEDAEMDAELELEMAHGLGPGPRLPTGSPGAPGRGPGGAGGGGD
TEGGLCRRCYSPAQENLWLDSVSLIIKDSLEGELTIIDNLSGSIFHHYSSPAGCKKCH
HDKQEVQLAETEAFSLNSDRSSSILLGDDLSLEDPTACPPGRKDSKGELDPPEPMRVG
DLGECFFPLSSTAVSPDPENFLCEMEEIPFNPVRSWLKHDSSQAPPSPFSPDASSPLL
PMPAEFFHPAVSASQKGPEKGTGTGTLPKIALQGSWASLRSPRVNCTLLRQATGSDTS
LDASPSSSAGSLQTTLEDSLTLSDSPRRALGPPAPAPGPRAGLSPAARRRLSLRGRGL
FSLRGLRAHQRSHSSGGSTSPGCTHHDSMDPSDEEGRGGAGGGGAGSEHSETLSSLSL
TSLFCPPPPPPAPGLTPARKFSSTSSLAAPGRPHAAALAHGLARSPSWAADRSKDPPG
RAPLPMGLGPLAPPPQPLPGELEPGDAASKRKR"
BASE COUNT 1279 a 2335 c 2054 g 1322 t
ORIGIN
1 atggctgaga gcgcctcccc gccctcctca tctgcagcag ccccagccgc tgagccagga
61 gtcaccacgg agcagcccgg accccggagc cccccatcct ccccgccagg cctggaggag
121 cctctggatg gagctgatcc tcatgtccca cacccagacc tggcgcctat tgccttcttc
181 tgcctgcgac agaccaccag cccccggaac tggtgcatca agatggtgtg caacccgtgg
241 tttgaatgtg tcagcatgct ggtgatcctg ctgaactgcg tgacacttgg catgtaccag
301 ccgtgcgacg acatggactg cctgtccgac cgctgcaaga tcctgcaggt ctttgatgac
361 ttcatcttta tcttctttgc catggagatg gtgctcaaga tggtggccct ggggattttt
421 ggcaagaagt gctacctcgg ggacacatgg aaccgcctgg atttcttcat cgtcatggca
481 gggatggtcg agtactccct ggaccttcag aacatcaacc tgtcagccat ccgcaccgtg
541 cgcgtcctga ggcccctcaa agccatcaac cgcgtgccca gtatgcggat cctggtgaac
601 ctgctcctgg acacactgcc catgctgggg aatgtcctgc tgctctgctt ctttgtcttc
661 ttcatctttg gcatcatagg tgtgcagctc tgggcgggcc tgctgcgtaa ccgctgcttc
721 ctggaggaga acttcaccat acaaggggat gtggccttgc ccccatacta ccagccggag
781 gaggatgatg agatgccctt catctgctcc ctgtcgggcg acaatgggat aatgggctgc
841 catgagatcc ccccgctcaa ggagcagggc cgtgagtgct gcctgtccaa ggacgacgtc
901 tacgactttg gggcggggcg ccaggacctc aatgccagcg gcctctgtgt caactggaac
961 cgttactaca atgtgtgccg cacgggcagc gccaaccccc acaagggtgc catcaacttt
1021 gacaacatcg gttatgcttg gattgtcatc ttccaggtga tcactctgga aggctgggtg
1081 gagatcatgt actacgtgat ggatgctcac tccttctaca acttcatcta cttcatcctg
1141 cttatcatag tgggctcctt cttcatgatc aacctgtgcc tcgttgtcat agcgacccag
1201 ttctcggaga ccaagcaacg ggagcaccgg ctgatgctgg agcagcggca gcgctacctg
1261 tcctccagca cggtggccag ctacgccgag cctggcgact gctacgagga gatcttccag
1321 tatgtctgcc acatcctgcg caaggccaag cgccgcgccc tgggcctcta ccaggccctg
1381 cagagccggc gccaggccct gggcccggag gccccggccc ccgccaaacc tgggccccac
1441 gccaaggagc cccggcacta ccatgggaag actaagggtc agggagatga agggagacat
1501 ctcggaagcc ggcattgcca gactttgcat gggcctgcct cccctggaaa tgatcactcg
1561 ggaagagagc tgtgcccgca acatagcccc ctggatgcga cgccccacac cctggtgcag
1621 cccatccccg ccacgctggc ttccgatccc gccagctgcc cttgctgcca gcatgaggac
1681 ggccggcggc cctcgggcct gggcagcacc gactcgggcc aggagggctc gggctccggg
1741 agctccgctg gtggcgagga cgaggcggat ggggacgggg cccggagcag cgaggacgga
1801 gcctcctcag aactggggaa ggaggaggag gaggaggagc aggcggatgg ggcggtctgg
1861 ctgtgcgggg atgtgtggcg ggagacgcga gccaagctgc gcggcatcgt ggacagcaag
1921 tacttcaacc ggggcatcat gatggccatc ctggtcaaca ccgtcagcat gggcatcgag
1981 caccacgagc agccggagga gctgaccaac atcctggaga tctgcaatgt ggtcttcacc
2041 agcatgtttg ccctggagat gatcctgaag ctggctgcat ttgggctctt cgactacctg
2101 cgtaacccct acaacatctt cgacagcatc attgtcatca tcagcatctg ggagatcgtg
2161 gggcaggcgg acggtgggct gtcggtgctg cggaccttcc ggctgctgcg cgtgctgaaa
2221 ctggtgcgct tcatgcctgc cctgcggcgc cagctcgtgg tgctcatgaa gaccatggac
2281 aacgtggcca ccttctgcat gctgctcatg ctcttcatct tcatcttcag catccttggg
2341 atgcatattt ttggctgcaa gttcagcctc cgcacggaca ctggagacac ggtgcccgac
2401 aggaagaact tcgactccct gctgtgggcc atcgtcactg tgttccagat cctcacccag
2461 gaggactgga acgtcgttct ctacaatggc atggcctcca cttctccctg ggcctccctc
2521 tactttgtcg ccctcatgac cttcggcaac tatgtgctct tcaacctgct ggtggccatc
2581 ctggtggagg gcttccaggc ggagggtgac gccaatcgct cctactcgga cgaggaccag
2641 agctcatcca acatagaaga gtttgataag ctccaggaag gcctggacag cagcggagat
2701 cccaagctct gcccaatccc catgaccccc aatgggcacc tggaccccag tctcccactg
2761 ggtgggcacc taggtcctgc tggggctgcg ggacctgccc cccgactctc actgcagccg
2821 gaccccatgc tggtggccct gggctcccga aagagcagtg tcatgtctct agggaggatg
2881 agctatgacc agcgctccct gtccagctcc cggagctcct actacgggcc atggggccgc
2941 agcgcggcct gggccagccg tcgctccagc tggaacagcc tcaagcacaa gccgccgtcg
3001 gcggagcatg agtccctgct ctctgcggag cgcggcggcg gcgcccgggt ctgcgaggtt
3061 gccgcggacg aggggccgcc gcgggccgca cccctgcaca ccccacacgc ccaccacatt
3121 catcacgggc cccatctggc gcaccgccac cgccaccacc gccggacgct gtccctcgac
3181 aacagggact cggtggacct ggccgagctg gtgcccgcgg tgggcgccca cccccgggcc
3241 gcctggaggg cggcaggccc ggcccccggg catgaggact gcaatggcag gatgcccagc
3301 atcgccaaag acgtcttcac caagatgggc gaccgcgggg atcgcgggga ggatgaggag
3361 gaaatcgact acaccctgtg cttccgcgtc cgcaagatga tcgacgtcta taagcccgac
3421 tggtgcgagg tccgcgaaga ctggtctgtc tacctcttct ctcccgagaa caggttccgg
3481 gtcctgtgtc agaccattat tgcccacaaa ctcttcgact acgtcgtcct ggccttcatc
3541 tttctcaact gcatcaccat cgccctggag cggcctcaga tcgaggccgg cagcaccgaa
3601 cgcatctttc tcaccgtgtc caactacatc ttcacggcca tcttcgtggg cgagatgaca
3661 ttgaaggtag tctcgctggg cctgtacttc ggcgagcagg cgtacctacg cagcagctgg
3721 aacgtgctgg atggctttct tgtcttcgtg tccatcatcg acatcgtggt gtccctggcc
3781 tcagccgggg gagccaagat cttgggggtc ctccgagtct tgcggctcct gcgcacccta
3841 cgccccctgc gtgtcatcag ccgggcgccg ggcctgaagc tggtggtgga gacactcatc
3901 tcctccctca agcccatcgg caacatcgtg ctcatctgct gtgccttctt catcatcttt
3961 ggcatcctgg gagtgcagct cttcaagggc aagttctacc actgtctggg cgtggacacc
4021 cgcaacatca ccaaccgctc ggactgcatg gccgccaact accgctgggt ccatcacaaa
4081 tacaacttcg acaacctggg ccaggctctg atgtccctct ttgtcctggc atccaaggat
4141 ggttgggtga acatcatgta caatggactg gatgctgttg ctgtggacca gcagcctgtg
4201 accaaccaca acccctggat gctgctgtac ttcatctcct tcctgctcat cgtcagcttc
4261 tttgtgctca acatgtttgt gggtgtcgtg gtggagaact tccacaagtg ccggcagcac
4321 caggaggctg aagaggcacg gcggcgtgag gagaagcggc tgcggcgcct ggagaagaag
4381 cgccggaagg cccagcggct gccctactat gccacctatt gtcacacccg gctgctcatc
4441 cactccatgt gcaccagcca ctacctggac atcttcatca ccttcatcat ctgcctcaac
4501 gtggtcacca tgtccctgga gcactacaat cagcccacgt ccctggagac agccctcaag
4561 tactgcaact atatgttcac cactgtcttt gtgctggagg ctgtgctgaa gctggtggca
4621 tttggtctga ggcgcttctt caaggaccga tggaaccagc tggacctggc cattgtgcta
4681 ctgtcagtca tgggcatcac cctggaggag atcgagatca atgcggccct gcccatcaat
4741 cccaccatca tccgcatcat gagggttctg cgcattgccc gagtgctgaa gctgttgaag
4801 atggccacag gaatgcgggc cctgctggac acggtggtgc aagctttgcc ccaggtgggc
4861 aacctgggcc tcctcttcat gctgctcttc ttcatctatg ctgctctcgg ggtggagctc
4921 tttgggaagc tggtctgcaa cgacgagaac ccgtgcgagg gcatgagccg gcatgccacc
4981 ttcgagaact tcggcatggc cttcctcaca ctcttccagg tctccacggg tgacaactgg
5041 aacgggatca tgaaggacac gctgcgggac tgcacccacg acgagcgcag ctgcctgagc
5101 agcctgcagt ttgtgtcgcc gctgtacttc gtgagcttcg tgctcaccgc gcagttcgtg
5161 ctcatcaacg tggtggtggc tgtgctcatg aagcacctgg acgacagcaa caaggaggcg
5221 caggaggacg ccgagatgga tgccgagctc gagctggaga tggcccatgg cctgggccct
5281 ggcccgaggc tgcctaccgg ctccccgggc gcccctggcc gagggccggg aggggcgggc
5341 ggcgggggcg acaccgaggg cggcttgtgc cggcgctgct actcgcctgc ccaggagaac
5401 ctgtggctgg acagcgtctc tttaatcatc aaggactcct tggaggggga gctgaccatc
5461 atcgacaacc tgtcgggctc catcttccac cactactcct cgcctgccgg ctgcaagaag
5521 tgtcaccacg acaagcaaga ggtgcagctg gctgagacgg aggccttctc cctgaactca
5581 gacaggtcct cgtccatcct gctgggtgac gacctgagtc tcgaggaccc cacagcctgc
5641 ccacctggcc gcaaagacag caagggtgag ctggacccac ctgagcccat gcgtgtggga
5701 gacctgggcg aatgcttctt ccccttgtcc tctacggccg tctcgccgga tccagagaac
5761 ttcctgtgtg agatggagga gatcccattc aaccctgtcc ggtcctggct gaaacatgac
5821 agcagtcaag cacccccaag tcccttctcc ccggatgcct ccagccctct cctgcccatg
5881 ccagccgagt tcttccaccc tgcagtgtct gccagccaga aaggcccaga aaagggcact
5941 ggcactggaa ccctccccaa gattgcgctg cagggctcct gggcatctct gcggtcacca
6001 agggtcaact gtaccctcct ccggcaggcc accgggagcg acacgtcgct ggacgccagc
6061 cccagcagct ccgcgggcag cctgcagacc acgctcgagg acagcctgac cctgagcgac
6121 agcccccggc gtgccctggg gccgcccgcg cctgctccag gaccccgggc cggcctgtcc
6181 cccgccgctc gccgccgcct gagcctgcgc ggccggggcc tcttcagcct gcgggggctg
6241 cgggcgcatc agcgcagcca cagcagcggg ggctccacca gcccgggctg cacccaccac
6301 gactccatgg acccctcgga cgaggagggc cgcggtggcg cgggcggcgg gggcgcgggc
6361 agcgagcact cggagaccct cagcagcctc tcgctcacct ccctcttctg cccgccgccc
6421 ccgccgccag cccccggcct cacgcccgcc aggaagttca gcagcaccag cagcctggcc
6481 gcccccggcc gcccccacgc cgccgccctg gcccacggcc tggcccggag cccctcgtgg
6541 gccgcggacc gcagcaagga cccccccggc cgggcaccgc tgcccatggg cctgggcccc
6601 ttggcgcccc cgccgcaacc gctccccgga gagctggagc cgggagacgc cgccagcaag
6661 aggaagagat gagggtcgca ggggcccccg gccgcccacc gcccgccccg tctcaccttc
6721 tttacctcag gagccaggag cagacagcaa tacttcgtcc acacctggga tcgcgcaggg
6781 cccgcagggc acaggcgccc gacagccggg ctgagcggag tctgggttag ccaggcctgc
6841 gtggcccatg gtggcccttc cagtgcatat acatacatat atatatatat atgcatatat
6901 atatatatat atatatatat gtgtatacac acacacatag acagacatat atatatatat
6961 ttattttttt tactgagagc ttatgacttc
//