LOCUS AF141651 2933 bp DNA linear HUM 28-OCT-1999
DEFINITION Homo sapiens homeobox containing transcription factor SIX6 (SIX6)
gene, complete cds.
ACCESSION AF141651
VERSION AF141651.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2933)
AUTHORS Gallardo,M.E., Lopez-Rios,J., Fernaud-Espinosa,I., Granadino,B.,
Sanz,R., Ramos,C., Ayuso,C., Seller,M.J., Brunner,H.G.,
Bovolenta,P. and Rodriguez de Cordoba,S.
TITLE Genomic cloning and characterization of the human homeobox gene
SIX6 reveals a cluster of SIX genes in chromosome 14 and associates
SIX6 hemizygosity with bilateral anophthalmia and pituitary
anomalies
JOURNAL Genomics 61 (1), 82-91 (1999)
PUBMED 10512683
REFERENCE 2 (bases 1 to 2933)
AUTHORS Gallardo,M.E., Lopez-Rios,J., Fernaud-Espinosa,I., Granadino,B.,
Sanz,R., Ramos,C., Ayuso,C., Seller,M.J., Brunner,H.G.,
Bovolenta,P. and Rodriguez de Cordoba,S.
TITLE Direct Submission
JOURNAL Submitted (08-APR-1999) Inmunology, Centro de Investigaciones
Biologicas (CSIC), Velazquez 144, Madrid 28006, Spain
FEATURES Location/Qualifiers
source 1..2933
/organism="Homo sapiens"
/mol_type="genomic DNA"
/db_xref="taxon:9606"
/chromosome="14"
/map="14q22-q23"
gene 54..2618
/gene="SIX6"
/gene_synonym="SIX9"
mRNA join(54..720,1895..2618)
/gene="SIX6"
/gene_synonym="SIX9"
/product="homeobox containing transcription factor SIX6"
CDS join(149..720,1895..2063)
/gene="SIX6"
/gene_synonym="SIX9"
/codon_start=1
/product="homeobox containing transcription factor SIX6"
/protein_id="AAD49844.1"
/translation="MFQLPILNFSPQQVAGVCETLEESGDVERLGRFLWSLPVAPAAC
EALNKNESVLRARAIVAFHGGNYRELYHILENHKFTKESHAKLQALWLEAHYQEAEKL
RGRPLGPVDKYRVRKKFPLPRTIWDGEQKTHCFKERTRNLLREWYLQDPYPNPSKKRE
LAQATGLTPTQVGNWFKNRRQRDRAAAAKNRLQQQVLSQGSGRALRAEGDGTPEVLGV
ATSPAASLSSKAATSAISITSSDSECDI"
BASE COUNT 651 a 860 c 783 g 636 t
ORIGIN
1 gttgagccac cgccgccacc cggtagtgtg tcccgctgcc ccaatccgcc tcatcaacaa
61 gcgcctggca cactcagcca ggcccgcggg catctgctgc gtgtcccgct ccgggctcag
121 tgccctcgcc gccgccggca ctgcctcgat gttccagctg cccatcttga atttcagccc
181 ccagcaagtg gccggggtat gtgagaccct ggaagagagc ggcgatgtgg agcgcctggg
241 tcgcttcctc tggtcgctgc ccgtggcccc tgcggcctgc gaggccctca acaagaatga
301 gtcggtgcta cgcgcacgag ccatcgtggc ctttcacggt ggcaactacc gcgagctcta
361 tcatatcctg gaaaaccaca agttcaccaa ggagtcgcac gccaagctgc aggcgctgtg
421 gcttgaagcc cactaccagg aggctgagaa gctgcgtgga agacccctgg gacctgtgga
481 caagtaccga gtaaggaaga agttcccgct gccgcgcacc atttgggacg gcgaacagaa
541 gacacactgc ttcaaggagc gcacgcggaa cctgctacgc gagtggtacc tgcaggatcc
601 ataccctaac cccagcaaaa aacgtgagct cgcccaggca accggactga cccctacgca
661 ggtgggcaac tggttcaaaa accgccgaca aagggaccga gcggctgcag ccaagaacag
721 gtcggtacct agaggcctcc gcgctttgag cgcaccgggg aggaggcggg tggaggcacc
781 tctggcgccc ttacccagtc cctggcgact ccaattcagc aggagntggg agcgcggtct
841 gtcttgggtt aagagccctg cgttctgggc tcctggccgg gagttccctt gccggctctg
901 cttccccacc cgctggctcc ccacgcctgc gggcagctgc agcagctggt cccggtcacc
961 aaaccaaggc ttcactggga cggagagggg aagagaaata aaaaattaaa atcctacaaa
1021 cagttaggga ccccaagacc caaagctaat tcttgtcagc ctgggcacag gctcctacta
1081 ttaatcgaag cctggcttat tagcaatgtg tcggtttcat gttaattatc attttcaaag
1141 cccaggtata tccctcccta atgctttgaa aacagttttc aatggacttt tgagaaatgg
1201 gaagtcgagt tttcctcttc ccatgcgctg cctgccactc ttgtctcaaa acagcaaact
1261 agtccgtggg ccgaggcttt tcgtttcccg gagtgtggat ctcgatcagc caaacatttt
1321 gcggaagagc ccggcctcat cccccaggcc caaatgctcc ttacaatcct ttttgccttt
1381 aggtcgggcc gacccgatcc aacgcgatcg cgggagcact tgctcaggcg taagccccag
1441 gcagacgcac cgttagaaat ggtatcccat gtccctggga ccgatctgtc cttgtcaccc
1501 acgcttcgtt tatttcctga cagtcctgta aatctcccaa aagtgcacaa caaacaggga
1561 ggacactgca agcccagtat ataaaagacc tgggagctgc ggcgctgaga aagggcgcga
1621 atcatggtgg ggcacaacag tagggaccca cggaggggcg gccgcggact cctgcccgac
1681 ctctgtcncc ttgccgaagt aatcctcgcc ttaactgctg gggtcttcgg aagaacctct
1741 ctctgtcncc ttgccgaagt aatcctcgcc ttaactgctg gggtcttcgg aagaacctct
1801 agccgccggg ctggagggac gcaggaggtg gtgggggcgg gcgacgggcg gctgtgttac
1861 gagctgtgac ccgtgttccc tttcttcccc gtagactcca gcagcaggtc ctgtcacagg
1921 gttccgggcg ggcactacgg gcggagggcg acggcacgcc agaggtgctg ggcgtcgcca
1981 ccagcccggc cgccagtcta tccagcaagg cggccacttc agccatctcc atcacgtcca
2041 gcgacagcga gtgcgacatc tgagttgccc atccaggatg ctcagaagca gattccagtg
2101 taaaaacgag aaaaacaaaa tgaaagaggg gaagaagatg agagacctgc aaatccagcg
2161 ccagagaagc caggtgacca gggacccgcg ggctcgggtt gccgtttccc gccccacccc
2221 gcggccggcc tggcttcact ggcgcccttt ggccgcgacc acgggaacca gcggtgaggc
2281 ctgacccagc accacgttct tcttgctttg ctttttccta aggattttgc tgcaaagtct
2341 ccttcggaac ccgaactgca agctgagcgc ctgcccagat tctcccatgg gtatttcacg
2401 tcgaaaggac gctgttacat atgtataact ttcgctttaa agtttttttt taacaaaaca
2461 tatatatgct gtttatttac ttatttaaga gaccgccatg gtaggtttct ctgtagcttg
2521 gggaacttgc tgtttctaaa catgcaggct ggtggtgatg ggttctgtgt ggagaagcca
2581 aacaataaaa caacctagtg ggcaaccttc ttaattaagg gagctgctct cagattcctt
2641 ttcttcttat tattattaat atcattccct tcaccaggca tgcagggacc cttgagcaaa
2701 tggtctccgg aaggtcttac ctatatatct tttgccttct ttggtgcttc ctggtatatg
2761 ttttaaacaa cctatggtag gtctataacc acctcccacg tcaaattaca cgtatgtgca
2821 tatatgtatg tacctataca aacatatgta tgtatgcata cacgtgatat atttaaggct
2881 agaaattggc aacatgtgag cgtcctctct aaggcaagtc cccgcatccc cag
//