LOCUS AF140674 2848 bp mRNA linear HUM 26-SEP-1999
DEFINITION Homo sapiens zinc metalloprotease ADAMTS6 (ADAMTS6) mRNA, complete
cds.
ACCESSION AF140674
VERSION AF140674.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2848)
AUTHORS Hurskainen,T.L., Hirohata,S., Seldin,M.F. and Apte,S.S.
TITLE ADAM-TS5, ADAM-TS6, and ADAM-TS7, novel members of a new family of
zinc metalloproteases. General features and genomic distribution of
the ADAM-TS family
JOURNAL J. Biol. Chem. 274 (36), 25555-25563 (1999)
PUBMED 10464288
REFERENCE 2 (bases 1 to 2848)
AUTHORS Hurskainen,T.L., Hirohata,S., Seldin,M.F. and Apte,S.S.
TITLE Direct Submission
JOURNAL Submitted (06-APR-1999) Biomedical Engineering/Wb-3, The Cleveland
Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA
FEATURES Location/Qualifiers
source 1..2848
/db_xref="H-InvDB:HIT000071145"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="5"
gene 1..2848
/gene="ADAMTS6"
CDS 22..2604
/gene="ADAMTS6"
/note="contains a disintegrin-like and metalloprotease
domain with thrombospondin type I motifs"
/codon_start=1
/product="zinc metalloprotease ADAMTS6"
/protein_id="AAD56357.1"
/translation="MEILWKTLTWILSLIMASSEFHSDHRLSYSSQEEFLTYLEHYQL
TIPIRVDQNGAFLSFTVKNDKHSRRRRSMDPIDPQQAVSKLFFKLSAYGKHFHLNLTL
NTDFVSKHFTVEYWGKDGPQWKHDFLDNCHYTGYLQDQRSTTKVALSNCVGLHGVIAT
EDEEYFIEPLKNTTEDSKHFSYENGHPHVIYKKSALQQRHLYDHSHCGVSDFTRSGKP
WWLNDTSTVSYSLPINNTHIHHRQKRSVSIERFVETLVVADKMMVGYHGRKDIEHYIL
SVMNIVAKLYRDSSLGNVVNIIVARLIVLTEDQPNLEINHHADKSLDSFCKWQKSILS
HQSDGNTIPENGIAHHDNAVLITRYDICTYKNKPCGTLGLASVAGMCEPERSCSINED
IGLGSAFTIAHEIVHNFGMNHDGIGNSCGRKVMKQQNYGSSHYCEYQSFFLVCLQSRX
HHQLFREVCRELWCLSKSNRCVTNSIPAAEGTLCQTGNIEKGWCYQGDCVPFGTWPQS
IDGGWGPWSLWGECSRTCGGGVSSSLRHCDSPAPSGGGKYCLGERKRYRSCNTDPCPL
GSRDFREKQCADFDNMPFRGKYYNWKPYTGGGVKPCALNCLAEGYNFYTERAPAVIDG
TQCNADSLDICINGECKHVGCDNILGSDAREDRCRVCGGGGSTCDAIEGFFNDSLPRG
GYMEVVQIPRGSVHIEVREVAMSKNYIALKSEGDDYYINGAWTIDWPRKFDVAGTAFH
YKRPTDEPESLEALGPTSENLIVMVLLQEQNLGIRYKFNVPITRTGSGDNEVGFTWNH
QPWSECSATCAGGKMPTRQPTQRARWRTKHILSYALCLLKKLIGNISCRFASSCNLAK
ETLL"
BASE COUNT 837 a 551 c 664 g 794 t
ORIGIN
1 aatcatccag ttttctaaat tatggaaatt ttgtggaaga cgttgacctg gattttgagc
61 ctcatcatgg cttcatcgga atttcatagt gaccacaggc tttcatacag ttctcaagag
121 gaattcctga cttatcttga acactaccag ctaactattc caataagggt tgatcaaaat
181 ggagcatttc tcagctttac tgtgaaaaat gataaacact caaggagaag acggagtatg
241 gaccctattg atccacagca ggcagtatct aagttatttt ttaaactttc agcctatggc
301 aagcactttc atctaaactt gactctcaac acagattttg tgtccaaaca ttttacagta
361 gaatattggg ggaaagatgg accccagtgg aaacatgatt ttttagacaa ctgtcattac
421 acaggatatt tgcaagatca acgtagtaca actaaagtgg ctttaagcaa ctgtgttggg
481 ttgcatggtg ttattgctac agaagatgaa gagtatttta tcgaaccttt aaagaatacc
541 acagaggatt ccaagcattt tagttatgaa aatggccacc ctcatgttat ttacaaaaag
601 tctgcccttc aacaacgaca tctgtatgat cactctcatt gtggggtttc ggatttcaca
661 agaagtggca aaccttggtg gctgaatgac acatccactg tttcttattc actaccaatt
721 aacaacacac atatccacca cagacagaag agatcagtga gcattgaacg gtttgtggag
781 acattggtag tggcagacaa aatgatggtg ggctaccatg gccgcaaaga cattgaacat
841 tacattttga gtgtgatgaa tattgttgcc aaactttacc gtgattccag cctaggaaac
901 gttgtgaata ttatagtggc ccgcttaatt gttctcacag aagatcagcc aaacttggag
961 ataaaccacc atgcagacaa gtccctcgat agcttctgta aatggcagaa atccattctc
1021 tcccaccaaa gtgatggaaa caccattcca gaaaatggga ttgcccacca cgataatgca
1081 gttcttatta ctagatatga tatctgcact tataaaaata agccctgtgg aacactgggc
1141 ttggcctctg tggctggaat gtgtgagcct gaaaggagct gcagcattaa tgaagacatt
1201 ggcctgggtt cagcttttac cattgcacat gagattgttc acaattttgg tatgaaccat
1261 gatggaattg gaaattcttg tggacgaaag gtcatgaagc agcaaaatta tggcagctca
1321 cattactgcg aataccaatc ctttttcctg gtctgcttgc agtcgagant acatcaccag
1381 ctttttagag aagtgtgtag agagctctgg tgtctcagca aaagcaaccg ctgtgtcacc
1441 aacagtattc cagcagctga ggggacactg tgtcaaactg ggaatattga aaaagggtgg
1501 tgttatcagg gagattgtgt tccttttggc acttggcccc agagcataga tgggggctgg
1561 ggtccctggt cactatgggg agagtgcagc aggacctgcg ggggaggcgt ntcctcatcc
1621 ctaagacact gtgacagtcc agcaccttca ggaggtggaa aatattgcct tggggaaagg
1681 aaacggtatc gctcctgtaa cacagatcca tgccctttgg gttcccgaga ttttcgagag
1741 aaacagtgtg cagactttga caatatgcct ttccgaggaa agtattataa ctggaaaccc
1801 tatactggag gtggggtaaa accttgtgca ttaaactgct tggctgaagg ttataatttc
1861 tacactgaac gtgctcctgc ggtgatcgat gggacccagt gcaatgcgga ttcactggat
1921 atctgcatca atggagaatg caagcacgta ggctgtgata atattttggg atctgatgct
1981 agggaagata gatgtcgagt ctgtggaggg ggcggaagca catgtgatgc cattgaaggg
2041 ttcttcaatg attcactgcc caggggaggc tacatggaag tggtgcagat accaagaggc
2101 tctgttcaca ttgaagttag agaagttgcc atgtcaaaga actatattgc tttaaaatct
2161 gaaggagatg attactatat taatggtgcc tggactattg actggcctag gaaatttgat
2221 gttgctggga cagcttttca ttacaagaga ccaactgatg aaccagaatc cttggaagct
2281 ctaggtccta cctcagaaaa tctcatcgtc atggttctgc ttcaagaaca gaatttggga
2341 attaggtata agttcaatgt tcccatcact cgaactggca gtggagataa tgaagttggc
2401 tttacatgga atcatcagcc ttggtcagaa tgctcagcta cttgtgctgg aggtaagatg
2461 cccactaggc agcccaccca gagggcaaga tggagaacaa aacacattct gagctatgct
2521 ttgtgtttgt taaaaaagct aattggaaac atttcttgca ggtttgcttc aagctgtaat
2581 ttagcaaaag aaactttgct ttaattatat tatattccat ttgttttcaa cctcatgtaa
2641 tttgtgcaga tttgttggta aaatacatct tggcacaatg agtgtctctg ctggtgcttc
2701 tcccaagact atcttgaagg tgggctgttt gcctttcgtg aacacattct tggtaaagaa
2761 catcaaaagt tttaaaaaag aaaatgagca agaatcagac atcacagatg caacttcttg
2821 taatgggaga tgagaatgta cggctgtg
//