LOCUS AF137378 3983 bp mRNA linear HUM 21-SEP-1999
DEFINITION Homo sapiens integrin alpha 11 subunit precursor (ITGA11) mRNA,
complete cds.
ACCESSION AF137378
VERSION AF137378.2
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3983)
AUTHORS Velling,T., Kusche-Gullberg,M., Sejersen,T. and Gullberg,D.
TITLE cDNA cloning and chromosomal localization of human alpha(11)
integrin. A collagen-binding, I domain-containing,
beta(1)-associated integrin alpha-chain present in muscle tissues
JOURNAL J. Biol. Chem. 274 (36), 25735-25742 (1999)
PUBMED 10464311
REFERENCE 2 (bases 1 to 3983)
AUTHORS Velling,T., Kusche-Gullberg,M., Sejersen,T. and Gullberg,D.
TITLE Direct Submission
JOURNAL Submitted (24-MAR-1999) Cell and Molecular Biology, Box 596,
Uppsala S-75124, Sweden
REFERENCE 3 (bases 1 to 3983)
AUTHORS Velling,T., Kusche-Gullberg,M., Sejersen,T. and Gullberg,D.
TITLE Direct Submission
JOURNAL Submitted (21-SEP-1999) Cell and Molecular Biology, Box 596,
Uppsala S-75124, Sweden
REMARK Sequence update by submitter
COMMENT On Sep 21, 1999 this sequence version replaced AF137378.1.
FEATURES Location/Qualifiers
source 1..3983
/db_xref="H-InvDB:HIT000071102"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="15"
/map="15q23"
gene 1..3983
/gene="ITGA11"
5'UTR 1..90
/gene="ITGA11"
CDS 91..3657
/gene="ITGA11"
/function="cell surface receptor subunit"
/codon_start=1
/product="integrin alpha 11 subunit precursor"
/protein_id="AAD51919.2"
/translation="MDLPRGLVVAWALSLWPGFTDTFNMDTRKPRVIPGSRTAFFGYT
VQQHDISGNKWLVVGAPLETNGYQKTGDVYKCPVIHGNCTKLNLGRVTLSNVSERKDN
MRLGLSLATNPKDNSFLACSPLWSHECGSSYYTTGMCSRVNSNFRFSKTVAPALQRCQ
TYMDIVIVLDGSNSIYPWVEVQHFLINILKKFYIGPGQIQVGVVQYGEDVVHEFHLND
YRSVKDVVEAASHIEQRGGTETRTAFGIEFARSEAFQKGGRKGAKKVMIVITDGESHD
SPDLEKVIQQSERDNVTRYAVAVLGYYNRRGINPETFLNEIKYIASDPDDKHFFNVTD
EAALKDIVDALGDRIFSLEGTNKNETSFGLEMSQTGFSSHVVEDGVLLGAVGAYDWNG
AVLKETSAGKVIPLRESYLKEFPEELKNHGAYLGYTVTSVVSSRQGRVYVAGAPRFNH
TGKVILFTMHNNRSLTIHQAMRGQQIGSYFGSEITSVDIDGDGVTDVLLVGAPMYFNE
GRERGKVYVYELRQNRFVYNGTLKDSHSYQNARFGSSIASVRDLNQDSYNDVVVGAPL
EDNHAGAIYIFHGFRGSILKTPKQRITASELATGLQYFGCSIHGQLDLNEDGLIDLAV
GALGNAVILWSRPVVQINASLHFEPSKINIFHRDCKRSGRDATCLAAFLCFTPIFLAP
HFQTTTVGIRYNATMDERRYTPRAHLDEGGDRFTNRAVLLSSGQELCERINFHVLDTA
DYVKPVTFSVEYSLEDPDHGPMLDDGWPTTLRVSVPFWNGCNEDEHCVPDLVLDARSD
LPTAMEYCQRVLRKPAQDCSAYTLSFDTTVFIIESTRQRVAVEATLENRGENAYSTVL
NISQSANLQFASLIQKEDSDGSIECVNEERRLQKQVCNVSYPFFRAKAKVAFRLDFEF
SKSIFLHHLEIELAAGSDSNERDSTKEDNVAPLRFHLKYEADVLFTRSSSLSHYEVKL
NSSLERYDGIGPPFSCIFRIQNLGLFPIHGMMMKITIPIATRSGNRLLKLRDFLTDEA
NTSCNIWGNSTEYRPTPVEEDLRRAPQLNHSNSDVVSINCNIRLVPNQEINFHLLGNL
WLRSLKALKYKSMKIMVNAALQRQFHSPFIFREEDPSRQIVFEISKQEDWQVPIWIIV
GSTLGGLLLLALLVLALWKLGFFRSARRRREPGLDPTPKVLE"
misc_feature 91..3513
/gene="ITGA11"
/note="extracellular domain; other site"
sig_peptide 91..156
/gene="ITGA11"
mat_peptide 157..3654
/gene="ITGA11"
/product="integrin alpha 11 subunit"
misc_feature 334..336
/gene="ITGA11"
/note="glycosylation site"
misc_feature 373..375
/gene="ITGA11"
/note="glycosylation site"
misc_feature 568..1155
/gene="ITGA11"
/note="I-domain; other site"
misc_feature 961..963
/gene="ITGA11"
/note="glycosylation site"
misc_feature 1081..1083
/gene="ITGA11"
/note="glycosylation site"
misc_feature 1162..1164
/gene="ITGA11"
/note="glycosylation site"
misc_feature 1435..1437
/gene="ITGA11"
/note="glycosylation site"
misc_feature 1474..1476
/gene="ITGA11"
/note="glycosylation site"
misc_feature 1672..1674
/gene="ITGA11"
/note="glycosylation site"
misc_feature 2014..2016
/gene="ITGA11"
/note="glycosylation site"
misc_feature 2170..2172
/gene="ITGA11"
/note="glycosylation site"
misc_feature 2659..2661
/gene="ITGA11"
/note="glycosylation site"
misc_feature 2770..2772
/gene="ITGA11"
/note="glycosylation site"
misc_feature 3007..3009
/gene="ITGA11"
/note="glycosylation site"
misc_feature 3181..3183
/gene="ITGA11"
/note="glycosylation site"
misc_feature 3205..3207
/gene="ITGA11"
/note="glycosylation site"
misc_feature 3265..3267
/gene="ITGA11"
/note="glycosylation site"
misc_feature 3514..3582
/gene="ITGA11"
/note="transmembrane region"
misc_feature 3583..3654
/gene="ITGA11"
/note="cytoplasmic domain; other site"
3'UTR 3658..3983
/gene="ITGA11"
BASE COUNT 928 a 1171 c 1118 g 766 t
ORIGIN
1 ggcacgaggc cgcgccgagg aggctgccgc tctggcttgc cagtcccccg ccgccgctgc
61 acaccggacc cagccgccgt gccgcgggcc atggacctgc ccaggggcct ggtggtggcc
121 tgggcgctca gcctgtggcc agggttcacg gacaccttca acatggacac caggaagccc
181 cgggtcatcc ctggctccag gaccgccttc tttggctaca cagtgcagca gcacgacatc
241 agtggcaata agtggctggt cgtgggcgcc ccactggaaa ccaatggcta ccagaagacg
301 ggagacgtgt acaagtgtcc agtgatccac gggaactgca ccaaactcaa cctgggaagg
361 gtcaccctgt ccaacgtgtc cgagcggaaa gacaacatgc gcctcggcct tagtctcgcc
421 accaacccca aggacaacag cttcctggcc tgcagccccc tctggtctca tgagtgtggg
481 agctcctact acaccacagg gatgtgttca agagtcaact ccaacttcag gttctccaag
541 accgtggccc cagctctcca aaggtgccag acctacatgg acatcgtcat tgtcctggat
601 ggctccaaca gcatctaccc ctgggtggag gttcagcact tcctcatcaa catcctgaaa
661 aagttttaca ttggcccagg gcagatccag gttggagttg tgcagtatgg cgaagatgtg
721 gtgcatgagt ttcacctcaa cgactacagg tctgtaaaag atgtggtgga agctgccagc
781 cacattgagc agagaggagg aacagagacc cggacggcat ttggcattga atttgcacgc
841 tcagaggctt tccagaaggg tggaaggaaa ggagccaaga aggtgatgat tgtcatcaca
901 gatggggagt cccacgacag cccagacctg gagaaggtga tccagcaaag cgaaagagac
961 aacgtaacaa gatatgcggt ggccgtcctg ggctactaca accgcagggg gatcaatcca
1021 gaaacttttc taaatgaaat caaatacatc gccagtgacc ctgatgacaa gcacttcttc
1081 aatgtcactg atgaggctgc cttgaaggac attgtcgatg ccctggggga cagaatcttc
1141 agcctggaag gcaccaacaa gaacgagacc tcctttgggc tggagatgtc acagacgggc
1201 ttttcctcgc acgtggtgga ggatggggtt ctgctgggag ccgtcggtgc ctatgactgg
1261 aatggagctg tgctaaagga gacgagtgcc gggaaggtca ttcctctccg cgagtcctac
1321 ctgaaagagt tccccgagga gctcaagaac catggtgcat acctggggta cacagtcaca
1381 tcggtcgtgt cctccaggca ggggcgagtg tacgtggccg gagccccccg gttcaaccac
1441 acgggcaagg tcatcctgtt caccatgcac aacaaccgga gcctcaccat ccaccaggct
1501 atgcggggcc agcagatagg ctcttacttt gggagtgaaa tcacctcggt ggacatcgac
1561 ggcgacggcg tgactgatgt cctgctggtg ggcgcaccca tgtacttcaa cgagggccgt
1621 gagcgaggca aggtgtacgt ctatgagctg agacagaacc ggtttgttta taacggaacg
1681 ctaaaggatt cacacagtta ccagaatgcc cgatttgggt cctccattgc ctcagttcga
1741 gacctcaacc aggattccta caatgacgtg gtggtgggag cccccctgga ggacaaccac
1801 gcaggagcca tctacatctt ccacggcttc cgaggcagca tcctgaagac acctaagcag
1861 agaatcacag cctcagagct ggctaccggc ctccagtatt ttggctgcag catccacggg
1921 caattggacc tcaatgagga tgggctcatc gacctggcag tgggagccct tggcaacgct
1981 gtgattctgt ggtcccgccc agtggttcag atcaatgcca gcctccactt tgagccatcc
2041 aagatcaaca tcttccacag agactgcaag cgcagtggca gggatgccac ctgcctggcc
2101 gccttcctct gcttcacgcc catcttcctg gcaccccatt tccaaacaac aactgttggc
2161 atcagataca acgccaccat ggatgagagg cggtatacac cgagggccca cctggacgag
2221 ggcggggacc gattcaccaa cagagccgta ctgctctcct ccggccagga gctctgtgag
2281 cggatcaact tccatgtcct ggacactgct gactacgtga agccagtgac cttctcagtc
2341 gagtattccc tggaggaccc tgaccatggc cccatgctgg acgacggctg gcccaccact
2401 ctcagagtct cggtgccctt ctggaacggc tgcaatgagg atgagcactg tgtccctgac
2461 cttgtgttgg atgcccggag tgacctgccc acggccatgg agtactgcca gagggtgctg
2521 aggaagcctg cgcaggactg ctccgcatac acgctgtcct tcgacaccac agtcttcatc
2581 atagagagca cacgccagcg agtggcggtg gaggccacac tggagaacag gggcgagaac
2641 gcctacagta cggtcctaaa tatctcgcag tcagcaaacc tgcagtttgc cagcttgatc
2701 cagaaggagg actcagacgg tagcattgag tgtgtgaacg aggagaggag gctccagaag
2761 caagtctgca acgtcagcta tcccttcttc cgggccaagg ccaaggtggc tttccgtctt
2821 gattttgagt tcagcaaatc catcttccta caccacctgg agatcgagct cgctgcaggc
2881 agtgacagta atgagcggga cagcaccaag gaagacaacg tggccccctt acgcttccac
2941 ctcaaatacg aggctgacgt cctcttcacc aggagcagca gcctgagcca ctacgaggtc
3001 aagctcaaca gctcgctgga gagatacgat ggtatcgggc ctcccttcag ctgcatcttc
3061 aggatccaga acttgggctt gttccccatc cacgggatga tgatgaagat caccattccc
3121 atcgccacca ggagcggcaa ccgcctactg aagctgaggg acttcctcac ggacgaggcg
3181 aacacgtcct gtaacatctg gggcaatagc actgagtacc ggcccacccc agtggaggaa
3241 gacttgcgtc gtgctccaca gctgaatcac agcaactctg atgtcgtctc catcaactgc
3301 aatatacggc tggtccccaa ccaggaaatc aatttccatc tactggggaa cctgtggttg
3361 aggtccctaa aagcactcaa gtacaaatcc atgaaaatca tggtcaacgc agccttgcag
3421 aggcagttcc acagcccctt catcttccgt gaggaggatc ccagccgcca gatcgtgttt
3481 gagatctcca agcaagagga ctggcaggtc cccatctgga tcattgtagg cagcaccctg
3541 gggggcctcc tactgctggc cctgctggtc ctggcactgt ggaagctcgg cttctttaga
3601 agtgccaggc gcaggaggga gcctggtctg gaccccaccc ccaaagtgct ggagtgaggc
3661 tccagaggag actttgagtt gatgggggcc aggacaccag tccaggtagt gttgagaccc
3721 aggcctgtgg ccccaccgag ctggagcgga gaggaagcca gctggctttg cacttgacct
3781 catctcccga gcaatggcgc ctgctccctc cagaatggaa ctcaagctgg ttttaagtgg
3841 aactgcctac tgggagactg ggacaccttt acacagaccc ctagggattt aaagggacac
3901 ccctacacac acccaggccc acgccaaggc ctccctcagg ctctgtggag ggcatttgct
3961 gccccagcta ctaaggtgct agg
//