LOCUS AF136940 1425 bp mRNA linear HUM 10-MAY-2000
DEFINITION Homo sapiens sine oculis homeobox homolog 2 (SIX2) mRNA, complete
cds.
ACCESSION AF136940
VERSION AF136940.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1425)
AUTHORS Boucher,C.A., Winchester,C.L., Hamilton,G.M., Winter,A.D.,
Johnson,K.J. and Bailey,M.E.
TITLE Structure, mapping and expression of the human gene encoding the
homeodomain protein, SIX2
JOURNAL Gene 247 (1-2), 145-151 (2000)
PUBMED 10773454
REFERENCE 2 (bases 1 to 1425)
AUTHORS Boucher,C.A., Hamilton,G.M., Johnson,K.J. and Bailey,M.E.S.
TITLE Direct Submission
JOURNAL Submitted (24-MAR-1999) Division of Molecular Genetics, Institute
of Biomedical and Life Sciences, University of Glasgow, Anderson
College, 56 Dumbarton Rd., Glasgow G11 6NU, United Kingdom
FEATURES Location/Qualifiers
source 1..1425
/db_xref="H-InvDB:HIT000071092"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="2"
/map="2p15-p24"
gene 1..1425
/gene="SIX2"
CDS 53..928
/gene="SIX2"
/note="similar to Drosophila melanogaster sine oculus"
/codon_start=1
/product="sine oculis homeobox homolog 2"
/protein_id="AAF69032.1"
/translation="MSMLPTFGFTQEQVACVCEVLQQGGNIERLGRFLWSLPACEHLH
KNESVLKAKAVVAFHRGNFRELYKILESHQFSPHNHAKLQQLWLKAHYIEAEKLRGRP
LGAVGKYRVRRKFPLPRSIWDGEETSYCFKEKSRSVLREWYAHNPYPSPREKRELAEA
TGLTTTQVSNWFKNRRQRDRAAEAKERENNENSNSNSHNPLNGSGKSVLGSSEDEKTP
SGTPDHSSSSPALLLSPPPPGLPSLHSLGHPPGPSAVPVPVPGGGGADPLQHHHGLQD
SILNPMSANLVDLGS"
regulatory 1172..1177
/regulatory_class="polyA_signal_sequence"
/gene="SIX2"
BASE COUNT 250 a 481 c 387 g 307 t
ORIGIN
1 ccgcgcggcc cggtgagggc gcgcgcgggc gggcggggac gcagccggca ccatgtccat
61 gctgcccacc ttcggcttca cgcaggagca agtggcgtgc gtgtgcgagg tgctgcagca
121 gggcggcaac atcgagcggc tgggccgctt cctgtggtcg ctgcccgcct gcgagcacct
181 tcacaagaat gaaagcgtgc tcaaggccaa ggccgtggtg gccttccacc gcggcaactt
241 ccgcgagctc tacaagatcc tggagagcca ccagttctcg ccgcacaacc acgccaagct
301 gcagcagctg tggctcaagg cacactacat cgaggcggag aagctgcgcg gccgacccct
361 gggcgccgtg ggcaaatacc gcgtgcgccg caaattcccg ctgccgcgct ccatctggga
421 cggcgaggag accagctact gcttcaagga aaagagtcgc agcgtgctgc gcgagtggta
481 cgcgcacaac ccctaccctt caccccgcga gaagcgtgag ctggcggagg ccacgggcct
541 caccaccaca caggtcagca actggttcaa gaaccggcgg cagcgcgacc gggcggccga
601 ggccaaggaa agggagaaca acgagaactc caattctaac agccacaacc cgctgaatgg
661 cagcggcaag tcggtgttag gcagctcgga ggatgagaag actccatcgg ggacgccaga
721 ccactcatca tccagccccg cactgctcct cagcccgccg ccccctgggc tgccgtccct
781 gcacagcctg ggccaccctc cgggccccag cgcagtgcca gtgccggtgc caggcggagg
841 tggagcggac ccactgcaac accaccatgg cctgcaggac tccatcctca accccatgtc
901 agccaacctc gtggacctgg gctcctagaa cccatttgcc ttgatgagct tgccttttgt
961 gacttgacac tggggacgtg gagtggcggt gtccaggggc gccccgcccc tgcggcccca
1021 ccaggtactg aaagacccgc aggctgagcg ggtagaacag ccgggtaggg cagatagctg
1081 tctatgttgg ttcttgtttg ggatttattt tcaacaagtt acttttagga tccttttggg
1141 gctggagact gagtcttgaa ccacagaagg gaataaatta tacaccactg tcattctctc
1201 tctccctctg tctcttcctt ttaccctctc ttgtcttgcc ttttccccct ttcctcttcc
1261 tttcccttcc ttctcttttc ttttttctgc tttctgtctt tctccctctc cttgtattgc
1321 tttccttcta gatttctagc ttgccaccgt tcattctctc cttctgtctc tccctttctc
1381 tctccttctc tgtttctcct ctcttctctc ctgccagtct cttgc
//