LOCUS AF135026 8622 bp DNA linear HUM 24-SEP-2001
DEFINITION Homo sapiens kallikrein-like protein 3 (KLK9) gene, complete cds,
alternatively spliced.
ACCESSION AF135026
VERSION AF135026.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 8622)
AUTHORS Yousef,G.M., Luo,L.Y. and Diamandis,E.P.
TITLE Identification of novel human kallikrein-like genes on chromosome
19q13.3-q13.4
JOURNAL Anticancer Res. 19 (4B), 2843-2852 (1999)
PUBMED 10652563
REFERENCE 2 (bases 1 to 8622)
AUTHORS Diamandis,E.P., Yousef,G.M., Luo,L.Y., Magklara,A. and Obiezu,C.V.
TITLE The new human kallikrein gene family: implications in
carcinogenesis
JOURNAL Trends Endocrinol. Metab. 11 (2), 54-60 (2000)
PUBMED 10675891
REFERENCE 3 (bases 1 to 8622)
AUTHORS Yousef,G.M. and Diamandis,E.P.
TITLE The expanded human kallikrein gene family: locus characterization
and molecular cloning of a new member, KLK-L3 (KLK9)
JOURNAL Genomics 65 (2), 184-194 (2000)
PUBMED 10783266
REFERENCE 4 (bases 1 to 8622)
AUTHORS Yousef,G.M., Grass,L. and Diamandis,E.P.
TITLE Direct Submission
JOURNAL Submitted (13-MAR-1999) Pathology and Laboratory Medicine, Mount
Sinai Hospital, 600 University Avenue, Toronto, Ontario M5G 1X5,
Canada
FEATURES Location/Qualifiers
source 1..8622
/organism="Homo sapiens"
/mol_type="genomic DNA"
/db_xref="taxon:9606"
/chromosome="19"
/map="19q13.3-q13.4"
gene 1501..8622
/gene="KLK9"
mRNA join(1501..1630,1796..1952,4412..4677,7295..7431,
7875..8622)
/gene="KLK9"
/product="kallikrein-like protein 3"
mRNA join(1501..1630,1796..1952,4412..4571,7295..7431,
7875..8622)
/gene="KLK9"
/product="kallikrein-like protein 3 splice variant 1"
CDS join(1588..1630,1796..1952,4412..4571,7295..7431,
7875..8082)
/gene="KLK9"
/note="KLK-L3; alternatively spliced"
/codon_start=1
/product="kallikrein-like protein 3 splice variant 1"
/protein_id="AAG22845.1"
/translation="MKLGLLCALLSLLAGHGWADTRAIGAEECRPNSQPWQAGLFHLT
RLFCGATLISDRWLLTAAHCRKPYLWVRLGEHHLWKWEGPEQLFRVTDFFPHPGFNKD
LSANDHNDDIMLIRLPRQRCFQSHCSVPTSASWRTNSVTGHTLDTSRTACSVRACGRG
AEVPARVTLGAPWFAMEPWQAWCLGVLSPAPDPGAPQSTPAYATTLTGSKKSWRTEPA
RHGGTLEDQERPKGTG"
CDS join(1588..1630,1796..1952,4412..4677,7295..7431,
7875..8024)
/gene="KLK9"
/note="KLK-L3; alternatively spliced"
/codon_start=1
/product="kallikrein-like protein 3"
/protein_id="AAD26427.2"
/translation="MKLGLLCALLSLLAGHGWADTRAIGAEECRPNSQPWQAGLFHLT
RLFCGATLISDRWLLTAAHCRKPYLWVRLGEHHLWKWEGPEQLFRVTDFFPHPGFNKD
LSANDHNDDIMLIRLPRQARLSPAVQPLNLSQTCVSPGMQCLISGWGAVSSPKALFPV
TLQCANISILENKLCHWAYPGHISDSMLCAGLWEGGRGSCQGDSGGPLVCNGTLAGVV
SGGAEPCSRPRRPAVYTSVCHYLDWIQEIMEN"
BASE COUNT 2014 a 2203 c 2144 g 2261 t
ORIGIN
1 cttgaaccca ggaggcagag gttgcagtga gctgagatcg cgccactgta cttcagcctg
61 ggtgtcagag caatactccg ttttggaaaa caaacaaaca aacaaacaaa caaaaaacag
121 atggagcaac tgagagaggt cttgtgactt gcccaaagtc acacacctca tcactaatca
181 cacctaatca ttgagatttg gacacacatg gttcagttcc agagtccatg ctccaaacca
241 tgacgacaca gtgagagaac attcaagggg agcccagacc cagcttcata accaggcctg
301 tgagcaggag aaagtggaag ggatcgtaag tgcccagggg aggcaaagat ggactctgcc
361 tgaggatctc agagatttcc tggaggaggg agaattgagg ttgggtgttg aaggatgagt
421 gggagttcac caggaaaaga aggatatgga gaaagacatt cactcattca atgaacatct
481 cctgaggact tctgcaagcc ctgttccgcc tggaacgggg tgatgctggg acacagagat
541 gagtcagacc tgggcccagc cctccagaag ctgtccacct ggtgagaagg aatgatgagg
601 agagaggcag ggaggatggg gtgatggaag ggacaatggg gtggggggca gggagatgga
661 tgaaaaaaat atatagcaaa tgttctcagg atttggcaaa gatcaggatg tattaagaga
721 gagcacaggg cacttgctac ctggaaggtt gggcacctgg gtccttgggt ggtggagccg
781 tggggaaggg ggcaggttat gacaagagtg ggttaatcca gatggaacca gatttctcaa
841 cattctagga gagggccttg tccttgtggg aagaggccca aatccccagg gcagggaagg
901 ttctgcaagg tgtgtaaacc tgtgcagctg cctgtggtct ctgcctcact ccacctggat
961 ttccctcaat ctttcccgtg ttctgtctcc tcctcccact cctcctctca tcttgggtcc
1021 ttctgtgcct gtacctccct ctctttgtat cttttgctct tgtgtctgag tcctgactct
1081 gtcttccacc cctcgcctcc tttctgggtg gtccccctgc acatccctcc agcctgccgt
1141 gggaggttgg tctctgcaca ccactgcttt atccaaaata aacctgctgc accccaggac
1201 cttaggcttc aaggatctcc ctccttttcc aggacacaaa agattctgta tcttgtagcc
1261 taaggtgatg aggaatgagg tctcccactc tgaagacccc agaggaggtg cccacaacct
1321 ctccacaccc ccagcactcc tcctccattc agtcaagctc tggcccagca agccgccagt
1381 tcatcccaaa aggggggtcc ccctgcactt acctcctctc ccaaggcccc tgtcacagcc
1441 ccagggcttc cccctccccc aggtacattt cccaaccccg attaatcaca ggggcggccc
1501 catggaggag gaaggagatg gcatggctta ccataaagaa gcactggacg ccgggtgcac
1561 gttccaggat ccaggtgccc aggggtcatg aagctgggac tcctctgtgc tctgctctct
1621 ctgctggcag gtgaggctcc caggctggct gccccttcac ggctgtacta aggtcacctt
1681 gctcttccct cccatcccag gcttctgcct cctgccctct aggcttctca gcatcctctc
1741 cctgccctcc cagcctgctc ttcgctgacc cctttgtccc tcatccccac cccagggcat
1801 ggctgggcag acacccgtgc catcggggcc gaggaatgtc gccccaactc ccagccttgg
1861 caggccggcc tcttccacct tactcggctc ttctgtgggg cgaccctcat cagtgaccgc
1921 tggctgctca cagctgccca ctgccgcaag ccgtgagtga cccaggctgg ccatgctggg
1981 gagggacaga ggctgggggt caggagaggg tgaggggtgc tttaggccag aagtgcggag
2041 cctccacttc tgataccaca agttcaactc ttagaagtag gaagggtagc ctcccaaatc
2101 ctaaaattct agagaccagc aatatctcat ttgagaagtc taagattcga aacttaggct
2161 cttcgaatcc gagactgacc cagagaaatc cagaatcgta gaatcctaaa atcttgaatt
2221 tatgaaattc tgcaatagcc tcagcaaatt ttagaatcat agattcgcag actattagaa
2281 tcttagcagt ctgggtcagc actgcccaga ggaattatga tgccagccac atgtgtaagt
2341 ttaaatttct ggtggacaca tttaaaaaat aaggaatgag taaaattaat tctaatagat
2401 ttaacttgac atacccaaaa acttattttg acatgtaatc aatttttaaa tacgtatgaa
2461 cgatacagtt tacttttgtt ttggtactaa gcctttgaaa tctgttctgt attttacaca
2521 catagcctgt tacaaaatgg actagccaca tttcaagtgt tcaatagcca taatggctag
2581 tgtgatccta gaatcttaaa ttcagagctt tctagattca ttgaatattg aaactcacag
2641 tactagaatc tttgattcac agtatcctag aatattgaga ttcagataat tctgtagtct
2701 taaactattt gaatcccaga ctcttaaatt tctaaggtta tagatttata gaatgatgac
2761 attctagtct ttcttttttt tttttttttt tttttttgag acagagtctc cctctatctc
2821 ccaggctgga gtgcagtggc acaatctcag ctcactgcaa cctctgcctc tcgggttcaa
2881 gcaattctcc tgcctcagcc tcctgagtag ctgggattac aggtatgcac caccatgcca
2941 ggctattttt tttttttttt tttttttagt agagacgggg gtttcaccat attggccagg
3001 ctggtcttga actcctgacc ttgtgatctg cccgcctcgg cctcccaaag tgctgggatt
3061 acaggcgtga gccaccgcgc ccagccaaaa ttctagtctt tttgtcctag aacattaaaa
3121 ttctatgttc aaatcttaga tttaattcag ataatgttag aatcctggag tttttttgat
3181 ccaggggaat ctggaatgtt agaatcttgg attcataaaa ctctaaacct tgagcctcta
3241 gattctagaa tcatggataa tagtgtgtcg gaatctgaga attctagaat cttaggttct
3301 gggcattcta atagtatcct ggaatccacc tgatgcagga atcctctctc cattgcctct
3361 gaaaagtgac catccatact gttccaattt tcttccctcc atgagtaaag cactgattgt
3421 ggtaagagat gctgtgtggg aatttcccat catgcattgc tccatgatgg aacctccttt
3481 aacttaagcc tatacatcag actgggagaa cgatgttcag atttcagccg aaagtgaagc
3541 aggagaaatg cagagatatg aaggtggaag agagtgagag gcaggggaag ggtaggggga
3601 tgaagggatg taggggtgag gactactttt ccagatccag agccaagaca gcaagaatga
3661 cagagagaga cagacacaga tgtttctggt tccccaaccc tgaattcgca gtcattagcc
3721 tgctgcctaa tgtcagaggt cagaggctgg ggaatggact tgtcatcccc gaaaggatcc
3781 cagctgtcta gggcatggac cagaaatgaa acaagtgcgc tgagactgtg gtgagggctt
3841 aaggttagac accaggaaga catgcattga agggtgaagg atatgataga caggaaaagc
3901 tgaggccaga gatgaccccc aatttgggga ttttccatat cccatcccct ttcatacaca
3961 cgcacacgta tacacacaca ccacttagac atacagagcc gctcccacag aagccaccag
4021 acctgtgggg gcaggggtgg ggcggttgtt atgtggtagg tggggtcccc cgtgcccaca
4081 ccgttcctag ggacccaagt caccaccaag gctccaggtg agtagggagg aaggtggctc
4141 actcagcctg ggactaggag cgggggcttt gtggggagag ctacaaagat ggagacacac
4201 aaaacatcag agtggggacc agggacccag aggaggtgtg tgcctcgctt aaaatcacag
4261 taccctgggc cagacataga tgatgagggt gcagagaggg tgtgtggctt gcagagggtc
4321 acacagcacc ctgatggaca ggaaaagagg gctggggctg aaaggacttt tacctttccc
4381 ccagcttgac ctctgaggcc tgtcccagca ggtatctgtg ggtccgcctt ggagagcacc
4441 acctctggaa atgggagggt ccggagcagc tgttccgggt tacggacttc ttcccccacc
4501 ctggcttcaa caaggacctc agcgccaatg accacaatga tgacatcatg ctgatccgcc
4561 tgcccaggca ggcacgtctg agtcctgctg tgcagcccct caacctcagc cagacctgtg
4621 tctccccagg catgcagtgt ctcatctcag gctggggggc cgtgtccagc cccaagggta
4681 tgacctggcc cagaactctc tctgaaactt gctccctcac ccctctgtct ctgccttttc
4741 atctctgtct tctccttttc tctctcctct ctctctctgt cagtctatct atctgccaat
4801 cgatatattt aaccaaatat aagatgctag catttttaag atgtgccatt atttcatgaa
4861 ctgcgaagaa gtggaagaag gaggaggagg agaagaaaaa aaggaggagg aggaaagatc
4921 ccattagatc ccattgatta tataacacca ttttctggaa gacacattct aatttcagag
4981 tgtttgtttg tttgtttgtt tgtttgtttt tgagacaggg tctcgctttg ttgctcaggc
5041 tggagtgcag cggtgtgatc acggctcatt gcagctttga actcctgggc tcaagtgatc
5101 ctctcgcctc aacctcccaa gtagctggga ttacagatat gcaccaccac atcccacacc
5161 ggggtcattt ttttattatt tattattatt attattatta tctttttttt tgtattttta
5221 gtagagacag aggtttcacc atattggcca ggctggtctc aaattcctga cctggtgatc
5281 tgcccgcctt ggactcccaa agtgctggga aaacaggcat gagccactgc acccagccaa
5341 aattctagtc ttttttaaat ctagtcatat cttagattta attcagataa tgttagaatc
5401 ctggagtttt ttgatccagg ggaatctgga atgttagaat cttggattca taaaactcta
5461 aacgttgagc ctctagattc tagaatcatg gatactagtg tgtcagaatc tgagaattct
5521 agaatcttag attctgggca ttctaatagt atcctggaat ccacctgatg caggaatcct
5581 ctctccattg cctctgaaaa gtgaccatcc atactgttcc aattttcttc cctccatgaa
5641 taaagcactg attctggtaa aagatgctgg gtgggaattt cccatcatgc attgctccat
5701 gatgggacct cctttaactt aagccttatg ctaaaaattt ttattatttt tagcaaagat
5761 gaggtcttgc tatgttgtcc aggctagtct caaactcctg gcctcccaaa gtgctgagat
5821 tacaagtgtg agccactgta cctggcccag agatgtttaa atgtgaaatg cgttcatctt
5881 agaatgggaa taagaccatg tctctcagag tcacggatca ctgacccatt agccaaattg
5941 ggtcagtgga ttggaaaaac agtctgaatt tgttgctgcc aatatctaaa acttggaaag
6001 ttttatacaa aagccaggtt tctggattca cctgaaaaag tttgaagaac tcacattccc
6061 aaaatagcaa gcattgggct gagtcaatgg aggctgcccc cttcagccaa gataagttct
6121 ctgattcact ccaatggacc caaatggctc ctgtctccct gcacagcccc cgtccccgac
6181 ttctgtttac caattctgtt tatcatatcc cttgatgcat cggagcctgc acccatgtct
6241 tatatagatg cacatgtgta ttatatatcc atatccacat ctatactgac tacactgtat
6301 ctggtatctc tgtctatgtc tctgtctcca tcagtgacca tcttcctgca aatctctttc
6361 cttttatctc actgccttca ttccacccct tgaggtctgg gtctttttct atttcttttt
6421 tttttttttt taagagactg agtcttgctc ttgttgccca ggctggagtg cagtggtgtg
6481 atctcggctc actgcaacct ccacctcctg ggttttaagt gatcctcctg cctcagcctc
6541 ccgagtagct gggactacag gtgtgcaaca gcatgcccag ctgatttttt gtattttcag
6601 tagagacgga gtttcaccat gttggccagg atggtctcaa tctcttgacc ttgtgatccg
6661 cccgcctcag cctcccaaag tgctagggag ttatatatgc atctcctctt atctcttggc
6721 tctctgcatg catctttctg tttctcttcc ttcctttctt tttttttttt tttttttttt
6781 tttttttttt ttttttgaga cggagtcttg ctctgtctcc caggctggag tgcagtgacc
6841 agtctcggct cactgcaacc tccacctccc aggttcaagt gattctcgtg cctcagcctc
6901 ccgagtagct gggattacag gcgcctgcca ccatgcctgg ctaatttttg tatatttagc
6961 agagatgggg tttcaccatg ttggctgggc tggtctcaaa ctcctgacct caagcgatcc
7021 gccggcctcg gcctccaaaa cactgggatt acaggcatga gccacggtgc ccggccagcc
7081 tctctctcta cttggccctc ttcctccttg tctccatttg tttctcttgt gtgctatgac
7141 tgtctgtctg tcactgtctc ttgtctctat ctttgagagt cctaaatgtg gctccattgg
7201 tcctttggaa aagctgcagg gaggactcag ggcagtgggg tgctgagtgt gttggagaca
7261 gttgcagatc cttgacagtt ctcttccctg acagcgctgt ttccagtcac actgcagtgt
7321 gccaacatca gcatcctgga gaacaaactc tgtcactggg cataccctgg acacatctcg
7381 gacagcatgc tctgtgcggg cctgtgggag gggggccgag gttcctgcca ggtgagacct
7441 tactctgggg aaaatgaggc tgtcctgcca agttttctag gatttagggg agcagagggg
7501 tcggccccca gccttcctgg gtcaaaatga gaaggagact gggatacctg gttcctggga
7561 gaggacggga ccagggcctg gactccttag tgtaaaagag aaaaggtctg gaggtccaga
7621 cttctggatc tacaggagga gtgggctggg cgtccagagt ctgagtcctc ggggaggagg
7681 aggttaggtc ctgcggggag gtgggccctc tgagctttta ctcctgggtc tgaggaagaa
7741 gaggctggag atggaggact ctcggatgtt ggaggaggaa ggggctgggg cctttctggg
7801 agggaggaag tggcccgtgt aattgtcatg aacagagtgg cctaacagtt cctctgccct
7861 tctctcgcgt acagggtgac tctgggggcc ccctggtttg caatggaacc ttggcaggcg
7921 tggtgtctgg gggtgctgag ccctgctcca gaccccggcg ccccgcagtc tacaccagcg
7981 tatgccacta ccttgactgg atccaagaaa tcatggagaa ctgagcccgc gcgccacggg
8041 ggcaccttgg aagaccaaga gaggccgaag ggcacggggt agggggttct cgtagggtcc
8101 cagcctcaat ggttcccgcc ctggacctcc agctgccctg actcccctct ggacactaag
8161 actccgcccc tgaggctccg ccccctcacg aggtcaagca agacacagtc gcgccccctc
8221 ggaacggagc agggacacgc ccttcagagc ccgtctctat gacgtcaccg acagccatca
8281 cctccttctt ggaacagcac agcctgtggc tccgccccaa ggaaccactt acacaaaata
8341 gctccgcccc tcggaacttt gcccagtggg acttcccctc gggactccac cccttgtggc
8401 cccgcctcct tcaccagaga tctcgcccct cgtgatgtca ggggcgcagt agctccgccc
8461 acgtggagct cgggcggtgt agagctcagc cccttgtggc cccgtcctgg gcgtgtgctg
8521 ggtttgaatc ctggcggaga cctgggggga aattgaggga gggtctggat acctttagag
8581 ccaatgcaac ggatgatttt tcagtaaacg cgggaaacct ca
//