LOCUS AF135016 1482 bp mRNA linear HUM 20-JAN-2000
DEFINITION Homo sapiens protein phosphatase 2A 48 kDa regulatory subunit mRNA,
complete cds.
ACCESSION AF135016
VERSION AF135016.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1482)
AUTHORS Yan,Z., Fedorov,S.A., Mumby,M.C. and Williams,R.S.
TITLE PR48, a novel regulatory subunit of protein phosphatase 2A,
interacts with Cdc6 and modulates DNA replication in human cells
JOURNAL Mol. Cell. Biol. 20 (3), 1021-1029 (2000)
PUBMED 10629059
REFERENCE 2 (bases 1 to 1482)
AUTHORS Yan,Z. and Williams,R.S.
TITLE Direct Submission
JOURNAL Submitted (15-MAR-1999) Internal Medicine, University of Texas
Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX
75235, USA
FEATURES Location/Qualifiers
source 1..1482
/db_xref="H-InvDB:HIT000071027_04"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/tissue_type="placenta"
/clone_lib="pACT2: Clontech"
5'UTR 1..111
CDS 112..1356
/EC_number="3.1.3.16"
/function="modulates DNA replication"
/note="interacts with Cdc6"
/codon_start=1
/product="protein phosphatase 2A 48 kDa regulatory
subunit"
/protein_id="AAD38515.1"
/translation="MDDMGLVAKACGCPLYWKGPLFYGAGGERTGSVSVHKFVAMWRK
ILQNCHDDAAKFVHLLMSPGCNYLVQEDFVPFLQDVVNTHPGLSFLKEASEFHSRYIT
TVIQRIFYAVNRSWSGRITCAELRRSSFLQNVALLEEEADINQLTEFFSYEHFYVIYC
KFWELDTDHDLLIDADDLARHNDHALSTKMIDRIFSGAVTRGRKVQKEGKISYADFVW
FLISEEDKKTPTSIEYWFRCMDLDGDGALSMFELEYFYEEQCRRLDSMAIEALPFQDC
LCQMLDLVKPRTEGKITLQDLKRCKLANVFFDTFFNIEKYLDHEQKEQISLLRDGDSG
GPELSDWEKYAAEEYDILVAEETAGEPWEDGFEAELSPVEQKLSALRSPLAQRPFFEA
PSPLGAVDLYEYACGDEDLEPL"
3'UTR 1354..1482
BASE COUNT 306 a 458 c 453 g 265 t
ORIGIN
1 attccgacct tctacttccc cagaggacgc ccgcaggact ccgtcaacgt ggatgccgtc
61 atcagcaaga tcgagagcac cttcgcccgg ttcccccacg agagggccac catggatgac
121 atgggcctgg tggccaaggc ctgcggctgc cccctctact ggaaggggcc gctcttctat
181 ggcgccggcg gggagcgcac gggctccgtg tccgtccaca agttcgtcgc catgtggaga
241 aaaatcctcc agaactgcca cgacgacgcg gccaagttcg tccatctgct catgagcccc
301 ggctgcaact acctggtgca ggaggacttt gtccccttct tgcaggacgt ggtgaacacg
361 cacccggggc tgtcgttcct gaaggaggcg tccgagttcc actcgcgcta catcaccacg
421 gtcatccagc ggatcttcta cgccgtgaac cggtcctggt ccggcaggat cacctgcgcc
481 gagctgcgga ggagctcctt cctgcagaat gtggcgctgc tggaggagga ggcggacatc
541 aaccagctga ccgaattctt ctcgtacgag catttctacg tcatctactg caagttctgg
601 gagctggaca cggaccacga cctgctcatc gacgcggacg acctggcgcg gcacaatgac
661 cacgcccttt ctaccaagat gatagacagg atcttctcag gagcagtcac acgaggcaga
721 aaagtgcaga aggaagggaa gatcagctat gccgactttg tctggttttt gatctctgag
781 gaagacaaaa aaacaccgac cagcatcgag tactggttcc gctgcatgga cctggacggg
841 gacggcgccc tgtccatgtt cgagctcgag tacttctacg aggagcagtg ccgaaggctg
901 gacagcatgg ccatcgaggc cctgcccttc caggactgcc tctgccagat gctggacctg
961 gtcaagccga ggactgaagg gaagatcacg ctgcaggacc tgaagcgctg caagctggcc
1021 aacgtcttct tcgacacctt cttcaacatc gagaagtacc tcgaccacga gcagaaagag
1081 cagatctccc tgctcaggga cggtgacagc ggcggccccg agctctcgga ctgggagaag
1141 tacgcggccg aggagtacga catcctggtg gccgaggaga ccgcgggaga gccctgggag
1201 gacgggttcg aggccgagct cagccctgtg gagcagaagc tgagtgcgct gcgctccccg
1261 ctggcccaga ggcccttctt cgaggcgccc tcaccgctgg gcgccgtgga cctgtacgag
1321 tacgcatgcg gggacgagga cctggagccg ctgtgacgcc gcccgcgaga acgccgccgc
1381 ggggccgctc cccacgtgcc accaccgggc caccgcggct cgtgtaaaaa ctgttgtgga
1441 aaatgagtgc gtttgtacgg aatgataaac ttttatttat tc
//