LOCUS AF134870 4368 bp mRNA linear HUM 13-JUN-1999
DEFINITION Homo sapiens transcription factor NFAT5 mRNA, complete cds.
ACCESSION AF134870
VERSION AF134870.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4368)
AUTHORS Lopez-Rodriguez,C., Aramburu,J., Rakeman,A.S. and Rao,A.
TITLE NFAT5, a constitutively nuclear NFAT protein that does not
cooperate with Fos and Jun
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 96 (13), 7214-7219 (1999)
PUBMED 10377394
REFERENCE 2 (bases 1 to 4368)
AUTHORS Lopez-Rodriguez,C., Aramburu,J., Rakeman,A.S., Hogan,P.G. and
Rao,A.
TITLE Direct Submission
JOURNAL Submitted (15-MAR-1999) Pathology, Harvard Medical School, Center
for Blood Research, 200 Longwood Avenue, Boston, MA 02115, USA
FEATURES Location/Qualifiers
source 1..4368
/db_xref="H-InvDB:HIT000071020"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/tissue_type="brain"
CDS 1..4368
/note="nuclear factor of activated T cells; encodes
Rel-like DNA binding domain"
/codon_start=1
/product="transcription factor NFAT5"
/protein_id="AAD38360.1"
/translation="MGGACSSFTTSSSPTIYSTSVTDSKAMQVESCSSAVGVSNRGVS
EKQLTSNTVQQHPSTPKRHTVLYISPPPEDLLDNSRMSCQDEGCGLESEQSCSMWMED
SPSNFSNMSTSSYNDNTEVPRKSRKRNPKQRPGVKRRDCEESNMDIFDADSAKAPHYV
LSQLTTDNKGNSKAGNGTLENQKGTGVKKSPMLCGQYPVKSEGKELKIVVQPETQHRA
RYLTEGSRGSVKDRTQQGFPTVKLEGHNEPVVLQVFVGNDSGRVKPHGFYQACRVTGR
NTTPCKEVDIEGTTVIEVGLDPSNNMTLAVDCVGILKLRNADVEARIGIAGSKKKSTR
ARLVFRVNIMRKDGSTLTLQTPSSPILCTQPAGVPEILKKSLHSCSVKGEEEVFLIGK
NFLKGTKVIFQENVSDENSWKSEAEIDMELFHQNHLIVKVPPYHDQHITLPVSVGIYV
VTNAGRSHDVQPFTYTPDPAAAGALNVNVKKEISSPARPCSFEEAMKAMKTTGCNLDK
VNIIPNALMTPLIPSSMIKSEDVTPMEVTAEKRSSTIFKTTKSVGSTQQTLENISNIA
GNGSFSSPSSSHLPSENEKQQQIQPKAYNPETLTTIQTQDISQPGTFPAVSASSQLPN
SDALLQQATQFQTRETQSREILQSDGTVVNLSQLTEASQQQQQSPLQEQAQTLQQQIS
SNIFPSPNSVSQLQNTIQQLQAGSFTGSTASGSSGSVDLVQQVLEAQQQLSSVLFSAP
DGNENVQEQLSADIFQQVSQIQSGVSPGMFSSTEPTVHTRPDNLLPGRAESVHPQSEN
TLSNQQQQQQQQQQVMESSAAMVMEMQQSICQAAAQIQSELFPSTASANGNLQQSPVY
QQTSHMMSALSTNEDMQMQCELFSSPPAVSGNETSTTTTQQVATPGTTMFQTSSSGDG
EETGTQAKQIQNSVFQTMVQMQHSGDNQPQVNLFSSTKSMMSVQNSGTQQQGNGLFQQ
GNEMMSLQSGNFLQQSSHSQAQLFHPQNPIADAQNLSQETQGSLFHSPNPIVHSQTST
TSSEQMQPPMFHSQSTIAVLQGSSVPQDQQSTNIFLSQSPMNNLQTNTVAQEAFFAAP
NSISPLQSTSNSEQQAAFQQQAPISHIQTPMLSQEQAQPPQQGLFQPQVALGSLPPNP
MPQSQQGTMFQSQHSIVAMQSNSPSQEQQQQQQQQQQQQQQQQQSILFSNQNTMATMA
SPKQPPPNMIFNPNQNPMANQEQQNQSIFHQQSNMAPMNQEQQPMQFQSQSTVSSLQN
PGPTQSESSQTPLFHSSPQIQLVQGSPSSQEQQVTLFLSPASMSALQTSINQQDMQQS
PLYSPQNNMPGIQGATSSPQPQATLFHNTAGGTMNQLQNSPGSSQQTSGMFLFGIQNN
CSQLLTSGPATLPDQLMAISQPGQPQNEGQPPVTTLLSQQMPENSPLASSINTNQNIE
KIDLLVSLQNQGNNLTGSF"
BASE COUNT 1385 a 1068 c 872 g 1043 t
ORIGIN
1 atgggcggtg cttgcagctc ctttaccacc tcttccagcc ctaccattta ttctacctca
61 gtcaccgaca gcaaggctat gcaagtggag agctgctcct cagccgtggg ggtaagtaac
121 agaggggtaa gtgaaaagca gttaaccagt aacacagttc agcagcatcc atcaacaccg
181 aagaggcaca cagtcttgta catctcacca ccacctgagg acttgctgga taacagtcgg
241 atgtcctgcc aggatgaggg gtgtggattg gaatctgagc agagctgcag tatgtggatg
301 gaggattccc cctccaactt cagtaacatg agcaccagtt cctacaatga taacactgag
361 gtacctcgta aatcacgaaa acgaaatcca aagcagaggc cgggggtcaa acgacgagat
421 tgtgaagaat ctaatatgga tatatttgat gccgacagtg ccaaagcacc tcactatgtg
481 ctttctcagc ttaccacgga caacaaaggc aactcaaaag cgggaaatgg aacattggaa
541 aaccaaaaag gaactggagt aaagaagagc cctatgttgt gtggacaata tcctgttaaa
601 agtgagggaa aggagctgaa gatagttgta caacctgaga cacagcaccg agctcggtac
661 ctgactgagg gcagccgtgg ctcagtgaaa gatagaacac agcaaggctt tcctacagta
721 aagctggaag gccataatga acctgtagtg ttgcaagtgt ttgtgggcaa cgactctgga
781 cgagtgaaac cacatggatt ttatcaggcc tgcagagtaa ctggacgaaa tacaactcct
841 tgcaaagaag tggacattga aggcactact gttatagaag tcggccttga tcctagcaac
901 aacatgacac tggcggtgga ctgcgtaggg atattgaaat tgaggaatgc tgatgtcgaa
961 gccagaatag gaattgctgg ttccaagaag aaaagcactc gtgccagatt ggtttttcga
1021 gttaatatca tgaggaaaga tggctccact ttgacactgc aaacaccctc ttctccaatt
1081 ttgtgtactc agccagcagg agtgccagaa atcttaaaga aaagcttgca tagctgttca
1141 gtgaaaggag aagaagaagt gtttttaatc ggcaagaact ttctgaaagg aactaaagtt
1201 attttccaag aaaatgtttc tgatgaaaac tcttggaagt cagaagctga aattgatatg
1261 gaactatttc atcagaatca tcttattgtg aaggttcctc cctatcatga ccaacatata
1321 actttgcctg tgtcagtggg aatatatgta gtgacaaatg ctggaagatc tcatgatgtt
1381 caaccattca cttacactcc agacccagca gcagctggtg ctttgaatgt aaatgtgaag
1441 aaggaaatat ctagtccagc aagaccttgc tcttttgaag aggccatgaa agcaatgaaa
1501 actactggat gtaatttaga taaggtaaat attatcccta atgccctgat gactccactc
1561 ataccaagca gtatgattaa gagtgaagat gttactccaa tggaagtaac agcagaaaaa
1621 agatcttcca ctatttttaa gactacaaag tctgttggat caactcagca aacattagaa
1681 aacatctcaa acatagcagg aaatggctct ttttcatcac catcatcttc ccacctacct
1741 tctgaaaatg aaaaacagca gcagattcag cccaaggcat acaacccaga gaccctgaca
1801 actattcaaa cccaggacat ctcacagcct ggtacttttc cagcagtttc tgcttctagt
1861 cagctgccca acagcgatgc actattgcag caggctacac agtttcagac aagagaaact
1921 cagtctagag agatattaca gtcagatggt acagtggtta atttgtcaca actgactgag
1981 gcatcacaac aacagcagca gtcaccacta caagaacaag cacagacttt acagcagcag
2041 atttcatcaa atatttttcc atcaccaaat agtgtgagtc agcttcagaa tactattcag
2101 cagctgcaag cagggagttt cacaggcagt actgctagtg gcagcagtgg aagtgttgac
2161 ttggtccaac aagttttaga ggcacagcag cagttatctt cagttttatt ttctgctcca
2221 gatggtaatg agaatgttca agagcagctt agtgcagata tttttcaaca agtcagtcaa
2281 attcagagtg gtgtaagccc tggaatgttt tcctcaacag agccaacagt ccataccaga
2341 ccagataatt tattacctgg aagagctgaa agtgttcatc cacagtctga aaacacgtta
2401 tctaatcaac agcagcagca gcagcagcaa cagcaagtga tggaatcttc agccgcaatg
2461 gtgatggaga tgcaacagag tatctgccag gcagctgccc agattcagtc agagttattc
2521 ccttcaactg cttcagcaaa tggaaacctt cagcaatcgc cagtttacca gcagacttct
2581 cacatgatga gtgcattgtc taccaatgag gatatgcaaa tgcagtgtga attgttttct
2641 tctcctcctg cagtttctgg aaatgaaact tctacaacta ccacacagca ggttgcaacc
2701 cctggcacta ccatgtttca gacatcaagt tcaggagatg gagaagaaac tggaacacaa
2761 gcaaaacaga ttcagaacag tgtctttcag accatggtcc aaatgcaaca tagtggggac
2821 aatcaacctc aagttaacct tttttcatcc acaaaaagta tgatgagtgt tcagaatagt
2881 ggtacccaac aacaaggtaa tggtttattc cagcaaggga atgagatgat gtcacttcaa
2941 tctggaaatt ttttgcagca gtcttctcat tcacaggccc aactttttca tcctcaaaat
3001 cctattgccg atgctcagaa cctttcccag gaaactcaag gttctctctt tcatagtcca
3061 aatcctattg tccacagtca gacttctaca acctcctctg aacaaatgca gcctccaatg
3121 tttcactctc aaagtaccat tgctgtgtta cagggctctt cagttcctca agaccagcag
3181 tcaaccaaca tatttctttc ccagagtccc atgaataatc ttcagactaa cacagtagcc
3241 caagaagcat tttttgcagc accgaactca atttctccac ttcagtcaac atcaaacagt
3301 gaacaacaag ctgctttcca acagcaagct ccaatatcac acatccagac tcctatgctt
3361 tcccaagaac aggcacaacc cccgcagcag ggtttatttc agcctcaggt ggccctgggc
3421 tcccttccac ctaatccaat gcctcaaagc caacaaggaa ccatgttcca gtcacagcac
3481 tcaatagttg ccatgcagag taactctcca tcccaggaac agcagcagca gcagcaacag
3541 cagcagcaac agcagcagca acaacaacag agcattttat tcagtaatca gaataccatg
3601 gctacaatgg cgtctccaaa gcaaccacca ccaaacatga tattcaaccc aaatcaaaat
3661 ccaatggcta atcaggagca acagaaccag tcaatttttc accaacaaag taacatggcc
3721 ccaatgaatc aagagcaaca gcccatgcaa tttcagagtc agtccacagt ttcctcactt
3781 cagaacccag gtcctaccca gtcggaatca tcacagaccc ccttgttcca tagctctcct
3841 cagattcagt tggtacaagg gtcacctagt tctcaagagc agcaagtaac tctcttctta
3901 tctccagcat ccatgtctgc cttgcagacc agtataaatc aacaagatat gcaacagtct
3961 cctctttatt cccctcagaa caacatgcct ggaattcaag gagccacatc ttcgcctcaa
4021 ccacaggcta ctttatttca caacacagca ggaggcacaa tgaaccaact gcagaattct
4081 cctggctcat ctcagcagac atcaggaatg ttcttatttg gcattcaaaa taactgtagt
4141 cagcttttaa cctctggacc agctacattg cctgatcagt tgatggccat aagtcagcca
4201 ggccaaccac aaaacgaggg ccagccacct gtgacaacac ttctttctca gcaaatgcca
4261 gagaattctc cactggcatc ctctataaac accaaccaga acatcgaaaa gattgatttg
4321 cttgtttcat tgcaaaacca agggaacaac ttgactggct ccttttaa
//