LOCUS AF133845 4933 bp mRNA linear HUM 24-MAY-1999
DEFINITION Homo sapiens corin mRNA, complete cds.
ACCESSION AF133845
VERSION AF133845.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4933)
AUTHORS Yan,W., Sheng,N., Seto,M., Morser,J. and Wu,Q.
TITLE Corin, a mosaic transmembrane serine protease encoded by a novel
cDNA from human heart
JOURNAL J. Biol. Chem. 274 (21), 14926-14935 (1999)
PUBMED 10329693
REFERENCE 2 (bases 1 to 4933)
AUTHORS Yan,W., Morser,J. and Wu,Q.
TITLE Direct Submission
JOURNAL Submitted (09-MAR-1999) Cardiovascular Research, Berlex
Biosciences, 15049 San Pablo Avenue, Richmond, CA 94806, USA
FEATURES Location/Qualifiers
source 1..4933
/db_xref="H-InvDB:HIT000070988"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="4"
/map="4p12-p13"
/tissue_type="heart"
CDS 94..3222
/note="mosiac serine protease"
/codon_start=1
/product="corin"
/protein_id="AAD31850.1"
/translation="MKQSPALAPEERYRRAGSPKPVLRADDNNMGNGCSQKLATANLL
RFLLLVLIPCICALVLLLVILLSYVGTLQKVYFKSNGSEPLVTDGEIQGSDVILTNTI
YNQSTVVSTAHPDQHVPAWTTDASLPGDQSHRNTSACMNITHSQCQMLPYHATLTPLL
SVVRNMEMEKFLKFFTYLHRLSCYQHIMLFGCTLAFPECIIDGDDSHGLLPCRSFCEA
AKEGCESVLGMVNYSWPDFLRCSQFRNQTESSNVSRICFSPQQENGKQLLCGRGENFL
CASGICIPGKLQCNGYNDCDDWSDEAHCNCSENLFHCHTGKCLNYSLVCDGYDDCGDL
SDEQNCDCNPTTEHRCGDGRCIAMEWVCDGDHDCVDKSDEVNCSCHSQGLVECRNGQC
IPSTFQCDGDEDCKDGSDEENCSVIQTSCQEGDQRCLYNPCLDSCGGSSLCDPNNSLN
NCSQCEPITLELCMNLPYNSTSYPNYFGHRTQKEASISWESSLFPALVQTNCYKYLMF
FSCTILVPKCDVNTGERIPPCRALCEHSKERCESVLGIVGLQWPEDTDCSQFPEENSD
NQTCLMPDEYVEECSPSHFKCRSGQCVLASRRCDGQADCDDDSDEENCGCKERDLWEC
PSNKQCLKHTVICDGFPDCPDYMDEKNCSFCQDDELECANHACVSRDLWCDGEADCSD
SSDEWDCVTLSINVNSSSFLMVHRAATEHHVCADGWQEILSQLACKQMGLGEPSVTKL
IQEQEKEPRWLTLHSNWESLNGTTLHELLVNGQSCESRSKISLLCTKQDCGRRPAARM
NKRILGGRTSRPGRWPWQCSLQSEPSGHICGCVLIAKKWVLTVAHCFEGRENAAVWKV
VLGINNLDHPSVFMQTRFVKTIILHPRYSRAVVDYDISIVELSEDISETGYVRPVCLP
NPEQWLEPDTYCYITGWGHMGNKMPFKLQEGEVRIISLEHCQSYFDMKTITTRMICAG
YESGTVDSCMGDSGGPLVCEKPGGRWTLFGLTSWGSVCFSKVLGPGVYSNVSYFVEWI
KRQIYIQTFLLN"
BASE COUNT 1380 a 1043 c 1096 g 1414 t
ORIGIN
1 aaatcatccg tagtgcctcc ccgggggaca cgtagaggag agaaaagcga ccaagataaa
61 agtggacaga agaataagcg agacttttta tccatgaaac agtctcctgc cctcgctccg
121 gaagagcgct accgcagagc cgggtcccca aagccggtct tgagagctga tgacaataac
181 atgggcaatg gctgctctca gaagctggcg actgctaacc tcctccggtt cctattgctg
241 gtcctgattc catgtatctg tgctctcgtt ctcttgctgg tgatcctgct ttcctatgtt
301 ggaacattac aaaaggtcta ttttaaatca aatgggagtg aacctttggt cactgatggt
361 gaaatccaag ggtccgatgt tattcttaca aatacaattt ataaccagag cactgtggtg
421 tctactgcac atcccgacca acacgttcca gcctggacta cggatgcttc tctcccaggg
481 gaccaaagtc acaggaatac aagtgcctgt atgaacatca cccacagcca gtgtcagatg
541 ctgccctacc acgccacgct gacacctctc ctctcagttg tcagaaacat ggaaatggaa
601 aagttcctca agtttttcac atatctccat cgcctcagtt gctatcaaca tatcatgctg
661 tttggctgta ccctcgcctt ccctgagtgc atcattgatg gcgatgacag tcatggactc
721 ctgccctgta ggtccttctg tgaggctgca aaagaaggct gtgaatcagt cctggggatg
781 gtgaattact cctggccgga tttcctcaga tgctcccagt ttagaaacca aactgaaagc
841 agcaatgtca gcagaatttg cttctcacct cagcaggaaa acggaaagca attgctctgt
901 ggaaggggtg agaactttct gtgtgccagt ggaatctgca tccccgggaa actgcaatgt
961 aatggctaca acgactgtga cgactggagt gacgaggctc attgcaactg cagcgagaat
1021 ctgtttcact gtcacacagg caagtgcctt aattacagcc ttgtgtgtga tggatatgat
1081 gactgtgggg atttgagtga tgagcaaaac tgtgattgca atcccacaac agagcatcgc
1141 tgcggggacg ggcgctgcat cgccatggag tgggtgtgtg atggtgacca cgactgtgtg
1201 gataagtccg acgaggtcaa ctgctcctgt cacagccagg gtctggtgga atgcagaaat
1261 ggacaatgta tccccagcac gtttcaatgt gatggtgacg aggactgcaa ggatgggagt
1321 gatgaggaga actgcagcgt cattcagact tcatgtcaag aaggagacca aagatgcctc
1381 tacaatccct gccttgattc atgtggtggt agctctctct gtgacccgaa caacagtctg
1441 aataactgta gtcaatgtga accaattaca ttggaactct gcatgaattt gccctacaac
1501 agtacaagtt atccaaatta ttttggccac aggactcaaa aggaagcatc catcagctgg
1561 gagtcttctc ttttccctgc acttgttcaa accaactgtt ataaatacct catgttcttt
1621 tcttgcacca ttttggtacc aaaatgtgat gtgaatacag gcgagcgtat ccctccttgc
1681 agggcattgt gtgaacactc taaagaacgc tgtgagtctg ttcttgggat tgtgggccta
1741 cagtggcctg aagacacaga ttgcagtcaa tttccagagg aaaattcaga caatcaaacc
1801 tgcctgatgc ctgatgaata tgtggaagaa tgctcaccta gtcatttcaa gtgccgctca
1861 ggacagtgtg ttctggcttc cagaagatgt gatggccagg ccgactgtga cgatgacagt
1921 gatgaggaaa actgtggttg taaagagaga gatctttggg aatgtccatc caataaacaa
1981 tgtttgaagc acacagtgat ctgcgatggg ttcccagact gccctgatta catggacgag
2041 aaaaactgct cattttgcca agatgatgag ctggaatgtg caaaccatgc gtgtgtgtca
2101 cgtgacctgt ggtgtgatgg tgaagccgac tgctcagaca gttcagatga atgggactgt
2161 gtgaccctct ctataaatgt gaactcctct tcctttctga tggttcacag agctgccaca
2221 gaacaccatg tgtgtgcaga tggctggcag gagatattga gtcagctggc ctgcaagcag
2281 atgggtttag gagaaccatc tgtgaccaaa ttgatacagg aacaggagaa agagccgcgg
2341 tggctgacat tacactccaa ctgggagagc ctcaatggga ccactttaca tgaacttcta
2401 gtaaatgggc agtcttgtga gagcagaagt aaaatttctc ttctgtgtac taaacaagac
2461 tgtgggcgcc gccctgctgc ccgaatgaac aaaaggatcc ttggaggtcg gacgagtcgc
2521 cctggaaggt ggccatggca gtgttctctg cagagtgaac ccagtggaca tatctgtggc
2581 tgtgtcctca ttgccaagaa gtgggttctg acagttgccc actgcttcga ggggagagag
2641 aatgctgcag tttggaaagt ggtgcttggc atcaacaatc tagaccatcc atcagtgttc
2701 atgcagacac gctttgtgaa gaccatcatc ctgcatcccc gctacagtcg agcagtggtg
2761 gactatgaca tcagcatcgt tgagctgagt gaagacatca gtgagactgg ctacgtccgg
2821 cctgtctgct tgcccaaccc ggagcagtgg ctagagcctg acacgtactg ctatatcaca
2881 ggctggggcc acatgggcaa taaaatgcca tttaagctgc aagagggaga ggtccgcatt
2941 atttctctgg aacattgtca gtcctacttt gacatgaaga ccatcaccac tcggatgata
3001 tgtgctggct atgagtctgg cacagttgat tcatgcatgg gtgacagcgg tgggcctctt
3061 gtttgtgaga agcctggagg acggtggaca ttatttggat taacttcatg gggctccgtc
3121 tgcttttcca aagtcctggg gcctggcgtt tatagtaatg tgtcatattt cgtcgaatgg
3181 attaaaagac agatttacat ccagaccttt ctcctaaact aattataagg atgatcagag
3241 acttttgcca gctacactaa aagaaaatgg ccttcttgac tgtgaagagc tgcctgcaga
3301 gagctgtaca gaagcacttt tcatggacag aaatgctcaa tcgtgcactg caaatttgca
3361 tgtttgtttt ggactaattt ttttcaattt attttttcac cttcattttt ctcttatttc
3421 aagttcaatg aaagacttta caaaagcaaa caaagcagac tttgtccttt tgccaggcct
3481 aaccatgact gcagcacaaa attatcgact ctggcgagat ttaaaatcag gtgctacagt
3541 aacaggttat ggaatggtct cttttatcct atcacaaaaa aagacataga tatttaggct
3601 gattaattat ctctaccagt ttttgtttct caagctcagt gcatagtggt aaatttcagt
3661 gttaacattg gagacttgct tttctttttc tttttttata ccccacaatt cttttttatt
3721 acacttcgaa ttttagggta cacgagcaca acgtgcaggt tagttacata tgtatacatg
3781 tgccatgttg gtgtgctgaa cccagtaact cgtcatttga tttattaaaa gccaagataa
3841 tttacatgtt taaagtattt actattaccc ccttctaatg tttgcataat tctgagaact
3901 gataaaagac agcaataaaa gaccagtgtc atccatttag gtagcaagac atattgaatg
3961 caaagttctt tagatatcaa tattaacact tgacattatt ggacccccca ttctggatgt
4021 atatcaagat cataatttta tagaagagtc tctatagaac tgtcctcata gctgggtttg
4081 ttcaggatat atgagttggc tgattgagac tgcaacaact acatctatat ttatgggcaa
4141 tattttgttt tacttatgtg gcaaagaact ggatattaaa ctttgcaaaa gagaatttag
4201 atgagagatg caatttttta aaaagaaaat taatttgcat ccctcgttta attaaattta
4261 tttttcagtt ttcttgcgtt catccatacc aacaaagtca taaagagcat attttagagc
4321 acagtaagac tttgcatgga gtaaaacatt ttgtaatttt cctcaaaaga tgtttaatat
4381 ctggtttctt ctcattggta attaaaattt tagaaatgat ttttagctct aggccacttt
4441 acgcaactca atttctgaag caattagtgg taaaaagtat ttttccccac taaaaaactt
4501 taaaacacaa atcttcatat atacttaatt taattagtca ggcatccatt ttgcctttta
4561 aacaactagg attccctact aacctccacc agcaacctgg actgcctcag cattccaaat
4621 agatactacc tgcaatttta tacatgtatt tttgtatctt ttctgtgtgt aaacatagtt
4681 gaaattcaaa aagttgtagc aatttctata ctattcatct cctgtccttc agtttgtata
4741 aacctaagga gagtgtgaaa tccagcaact gaattgtggt cacgattgta tgaaagttca
4801 agaacatatg tcagttttgt tacagttgta gctacatact caatgtatca acttttagcc
4861 tgctcaactt aggctcagtg aaatatatat attatactta ttttaaataa ttcttaatac
4921 aaataaaatg gta
//