LOCUS AF132608 3369 bp mRNA linear HUM 06-MAY-1999
DEFINITION Homo sapiens histone deacetylase 5 mRNA, complete cds.
ACCESSION AF132608
VERSION AF132608.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3369)
AUTHORS Grozinger,C.M., Hassig,C.A. and Schreiber,S.L.
TITLE Three proteins define a class of human histone deacetylases related
to yeast Hda1p
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 96 (9), 4868-4873 (1999)
PUBMED 10220385
REFERENCE 2 (bases 1 to 3369)
AUTHORS Grozinger,C.M., Hassig,C.A. and Schreiber,S.L.
TITLE Direct Submission
JOURNAL Submitted (03-MAR-1999) Chemistry and Chemical Biology, Harvard
University, 12 Oxford Street, Cambridge, MA 02138, USA
FEATURES Location/Qualifiers
source 1..3369
/db_xref="H-InvDB:HIT000070901"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_line="Jurkat T cell"
CDS 1..3369
/note="HDAC5; similar to Saccaromyces cerevisiae Hda1p"
/codon_start=1
/product="histone deacetylase 5"
/protein_id="AAD29047.1"
/translation="MNSPNESDGMSGREPSLEILPRTSLHSIPVTVEVKPVLPRAMPS
SMGGGGGGSPSPVELRGALVGSVDPTLREQQLQQELLALKQQQQLQKQLLFAEFQKQH
DHLTRQHEVQLQKHLKQQQEMLAAKQQQEMLAAKRQQELEQQRQREQQRQEELEKQRL
EQQLLILRNKEKSKESAIASTEVKLRLQEFLLSKSKEPTPGGLNHSLPQHPKCWGAHH
ASLDQSSPPQSGPPGTPPSYKLPLPGPYDSRDDFPLRKTASEPNLKVRSRLKQKVAER
RSSPLLRRKDGTVISTFKKRAVEITGAGPGASSVCNSAPGSGPSSPNSSHSTIAENGF
TGSVPNIPTEMLPQHRALPLDSSPNQFSLYTSPSLPNISLGLQATVTVTNSHLTASPK
LSTQQEAERQALQSLRQGGTLTGKFMSTSSIPGCLLGVALEGDGSPHGHASLLQHVLL
LEQARQQSTLIAVPLHGQSPLVTGERVATSMRTVGKLPRHRPLSRTQSSPLPQSPQAL
QQLVMQQQHQQFLEKQKQQQLQLGKILTKTGELPRQPTTHPEETEEELTEQQEVLLGE
GALTMPREGSTESESTQEDLEEEDEEEDGEEEEDCIQVKDEEGESGAEEGPDLEEPGA
GYKKLFSDAQPLQPLQVYQAPLSLATVPHQALGRTQSSPAAPGGMKSPPDQPVKHLFT
TGVVYDTFMLKHQCMCGNTHVHPEHAGRIQSIWSRLQETGLLSKCERIRGRKATLDEI
QTVHSEYHTLLYGTSPLNRQKLDSKKLLGPISQKMYAVLPCGGIGVDSDTVWNEMHSS
SAVRMAVGCLLELAFKVAAGELKNGFAIIRPPGHHAEESTAMGFCFFNSVAITAKLLQ
QKLNVGKVLIVDWDIHHGNGTQQAFYNDPSVLYISLHRYDNGNFFPGSGAPEEVGGGP
GVGYNVNVAWTGGVDPPIGDVEYLTAFRTVVMPIAHEFSPDVVLVSAGFDAVEGHLSP
LGGYSVTARCFGHLTRQLMTLAGGRVVLALEGGHDLTAICDASEACVSALLSVELQPL
DEAVLQQKPNINAVATLEKVIEIQSKHWSCVQKFAAGLGRSLREAQAGETEEAETVSA
MALLSVGAEQAQAAAAREHSPRPAEEPMEQEPAL"
BASE COUNT 727 a 1038 c 1039 g 565 t
ORIGIN
1 atgaactctc ccaacgagtc ggatgggatg tcaggtcggg aaccatcctt ggaaatcctg
61 ccgcggactt ctctgcacag catccctgtg acagtggagg tgaagccggt gctgccaaga
121 gccatgccca gttccatggg gggtgggggt ggaggcagcc ccagccctgt ggagctacgg
181 ggggctctgg tgggctctgt ggaccccaca ctgcgggagc agcaactgca gcaggagctc
241 ctggcgctca agcagcagca gcagctgcag aagcagctcc tgttcgctga gttccagaaa
301 cagcatgacc acctgacaag gcagcatgag gtccagctgc agaagcacct caagcagcag
361 caggagatgc tggcagccaa gcagcagcag gagatgctgg cagccaagcg gcagcaggag
421 ctggagcagc agcggcagcg ggagcagcag cggcaggaag agctggagaa gcagcggctg
481 gagcagcagc tgctcatcct gcggaacaag gagaagagca aagagagtgc cattgccagc
541 actgaggtaa agctgaggct ccaggaattc ctcttgtcga agtcaaagga gcccacacca
601 ggcggcctca accattccct cccacagcac cccaaatgct ggggagccca ccatgcttct
661 ttggaccaga gttcccctcc ccagagcggc ccccctggga cgcctccctc ctacaaactg
721 cctttgcctg ggccctacga cagtcgagac gacttccccc tccgcaaaac agcctctgaa
781 cccaacttga aagtgcgttc aaggctaaaa cagaaggtgg ctgagcggag aagcagtccc
841 ctcctgcgtc gcaaggatgg gactgttatt agcaccttta agaagagagc tgttgagatc
901 acaggtgccg ggcctggggc gtcgtccgtg tgtaacagcg cacccggctc cggccccagc
961 tctcccaaca gctcccacag caccatcgct gagaatggct ttactggctc agtccccaac
1021 atccccactg agatgctccc tcagcaccga gccctccctc tggacagctc ccccaaccag
1081 ttcagcctct acacgtctcc ttctctgccc aacatctccc tagggctgca ggccacggtc
1141 actgtcacca actcacacct cactgcctcc ccgaagctgt cgacacagca ggaggccgag
1201 aggcaggccc tccagtccct gcggcagggt ggcacgctga ccggcaagtt catgagcaca
1261 tcctctattc ctggctgcct gctgggcgtg gcactggagg gcgacgggag cccccacggg
1321 catgcctccc tgctgcagca tgtgctgttg ctggagcagg cccggcagca gagcaccctc
1381 attgctgtgc cactccacgg gcagtcccca ctagtgacgg gtgaacgtgt ggccaccagc
1441 atgcggacgg taggcaagct cccgcggcat cggcccctga gccgcactca gtcctcaccg
1501 ctgccgcaga gtccccaggc cctgcagcag ctggtcatgc aacaacagca ccagcagttc
1561 ctggagaagc agaagcagca gcagctacag ctgggcaaga tcctcaccaa gacaggggag
1621 ctgcccaggc agcccaccac ccaccctgag gagacagagg aggagctgac ggagcagcag
1681 gaggtcttgc tgggggaggg agccctgacc atgccccggg agggctccac agagagtgag
1741 agcacacagg aagacctgga ggaggaggac gaggaagagg atggggagga ggaggaggat
1801 tgcatccagg ttaaggacga ggagggcgag agtggtgctg aggaggggcc cgacttggag
1861 gagcctggtg ctggatacaa aaaactgttc tcagatgccc agccgctgca gcctttgcag
1921 gtgtaccagg cgcccctcag cctggccact gtgccccacc aggccctggg ccgtacccag
1981 tcctcccctg ctgcccctgg gggcatgaag agccccccag accagcccgt caagcacctc
2041 ttcaccacag gtgtggtcta cgacacgttc atgctaaagc accagtgcat gtgcgggaac
2101 acacacgtgc accctgagca tgctggccgg atccagagca tctggtcccg gctgcaggag
2161 acaggcctgc ttagcaagtg cgagcggatc cgaggtcgca aagccacgct agatgagatc
2221 cagacagtgc actctgaata ccacaccctg ctctatggga ccagtcccct caaccggcag
2281 aagctagaca gcaagaagtt gctcggcccc atcagccaga agatgtatgc tgtgctgcct
2341 tgtgggggca tcggggtgga cagtgacacc gtgtggaatg agatgcactc ctccagtgct
2401 gtgcgcatgg cagtgggctg cctgctggag ctggccttca aggtggctgc aggagagctc
2461 aagaatggat ttgccatcat ccggccccca ggacaccacg ccgaggaatc cacagccatg
2521 ggattctgct tcttcaactc tgtagccatc accgcaaaac tcctacagca gaagttgaac
2581 gtgggcaagg tcctcatcgt ggactgggac attcaccatg gcaatggcac ccagcaggcg
2641 ttctataatg acccctctgt gctctacatc tctctgcatc gctatgacaa cgggaacttc
2701 tttccaggct ctggggctcc tgaagaggtt ggtggaggac caggcgtggg gtacaatgtg
2761 aacgtggcat ggacaggagg tgtggacccc cccattggag acgtggagta ccttacagcc
2821 ttcaggacag tggtgatgcc cattgcccac gagttctcac ctgatgtggt cctagtctcc
2881 gccgggtttg atgctgttga aggacatctg tctcctctgg gtggctactc tgtcaccgcc
2941 agatgttttg gccacttgac caggcagctg atgaccctgg cagggggccg ggtggtgctg
3001 gccctggagg gaggccatga cttgaccgcc atctgtgatg cctctgaggc ttgtgtctcg
3061 gctctgctca gtgtagagct gcagcccttg gatgaggcag tcttgcagca aaagcccaac
3121 atcaacgcag tggccacgct agagaaagtc atcgagatcc agagcaaaca ctggagctgt
3181 gtgcagaagt tcgccgctgg tctgggccgg tccctgcgag aggcccaagc aggtgagacc
3241 gaggaggccg agactgtgag cgccatggcc ttgctgtcgg tgggggccga gcaggcccag
3301 gctgcggcag cccgggaaca cagccccagg ccggcagagg agcccatgga gcaggagcct
3361 gccctgtga
//