LOCUS AF131235 2032 bp mRNA linear HUM 10-AUG-1999
DEFINITION Homo sapiens N-acetylglucosamine 6-O-sulfotransferase mRNA,
complete cds.
ACCESSION AF131235
VERSION AF131235.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2032)
AUTHORS Bistrup,A., Bhakta,S., Lee,J.K., Belov,Y.Y., Gunn,M.D., Zuo,F.R.,
Huang,C.C., Kannagi,R., Rosen,S.D. and Hemmerich,S.
TITLE Sulfotransferases of two specificities function in the
reconstitution of high endothelial cell ligands for L-selectin
JOURNAL J. Cell Biol. 145 (4), 899-910 (1999)
PUBMED 10330415
REFERENCE 2 (bases 1 to 2032)
AUTHORS Bistrup,A., Tangemann,K., Bhakta,S., Lee,J.-K., Belov,Y.Y.,
Gunn,M.D., Zuo,F.-R., Huang,C.-C., Kannagi,R., Rosen,S.D. and
Hemmerich,S.
TITLE Direct Submission
JOURNAL Submitted (25-FEB-1999) Respiratory Diseases, Roche Bioscience,
3401 Hillview Avenue, Palo Alto, CA 94304, USA
FEATURES Location/Qualifiers
source 1..2032
/db_xref="H-InvDB:HIT000070739"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_type="high endothelial"
/tissue_type="tonsil"
CDS 182..1342
/function="biosynthesis of endothelial ligands for
L-selectin"
/note="HEC-GlcNAc-6-ST"
/codon_start=1
/product="N-acetylglucosamine 6-O-sulfotransferase"
/protein_id="AAD33015.1"
/translation="MLLPKKMKLLLFLVSQMAILALFFHMYSHNISSLSMKAQPERMH
VLVLSSWRSGSSFVGQLFGQHPDVFYLMEPAWHVWMTFKQSTAWMLHMAVRDLIRAVF
LCDMSVFDAYMEPGPRRQSSLFQWENSRALCSAPACDIIPQDEIIPRAHCRLLCSQQP
FEVVEKACRSYSHVVLKEVRFFNLQSLYPLLKDPSLNLHIVHLVRDPRAVFRSRERTK
GDLMIDSRIVMGQHEQKLKKEDQPYYVMQVICQSQLEIYKTIQSLPKALQERYLLVRY
EDLARAPVAQTSRMYEFVGLEFLPHLQTWVHNITRGKGMGDHAFHTNARDALNVSQAW
RWSLPYEKVSRLQKACGDAMNLLGYRHVRSEQEQRNLLLDLLSTWTVPEQIH"
BASE COUNT 468 a 569 c 490 g 505 t
ORIGIN
1 ggctcgaggc caggatgcct ccagtctggg ggaaaatgct tcctcatttg cttctcccag
61 cccacctcaa gcagtctccc caccccttga gtctcagcag tgttaaagct gttactttca
121 cagcttcctg ggagcgagtg ctttctcaag cccgtcttgc aaggtcttcc acttcagcac
181 aatgctactg cctaaaaaaa tgaagctcct gctgtttctg gtttcccaga tggccatctt
241 ggctctattc ttccacatgt acagccacaa catcagctcc ctgtctatga aggcacagcc
301 cgagcgcatg cacgtgctgg ttctgtcttc ctggcgctct ggctcttctt ttgtggggca
361 gctttttggg cagcacccag atgttttcta cctgatggag cccgcctggc acgtgtggat
421 gaccttcaag cagagcaccg cctggatgct gcacatggct gtgcgggatc tgatacgggc
481 cgtcttcttg tgcgacatga gcgtctttga tgcctacatg gaacctggtc cccggagaca
541 gtccagcctc tttcagtggg agaacagccg ggccctgtgt tctgcacctg cctgtgacat
601 catcccacaa gatgaaatca tcccccgggc tcactgcagg ctcctgtgca gtcaacagcc
661 ctttgaggtg gtggagaagg cctgccgctc ctacagccac gtggtgctca aggaggtgcg
721 cttcttcaac ctgcagtccc tctacccgct gctgaaagac ccctccctca acctgcatat
781 cgtgcacctg gtccgggacc cccgggccgt gttccgttcc cgagaacgca caaagggaga
841 tctcatgatt gacagtcgca ttgtgatggg gcagcatgag cagaaactca agaaggagga
901 ccaaccctac tatgtgatgc aggtcatctg ccaaagccag ctggagatct acaagaccat
961 ccagtccttg cccaaggccc tgcaggaacg ctacctgctt gtgcgctatg aggacctggc
1021 tcgagcccct gtggcccaga cttcccgaat gtatgaattc gtgggattgg aattcttgcc
1081 ccatcttcag acctgggtgc ataacatcac ccgaggcaag ggcatgggtg accacgcttt
1141 ccacacaaat gccagggatg cccttaatgt ctcccaggct tggcgctggt ctttgcccta
1201 tgaaaaggtt tctcgacttc agaaagcctg tggcgatgcc atgaatttgc tgggctaccg
1261 ccacgtcaga tctgaacaag aacagagaaa cctgttgctg gatcttctgt ctacctggac
1321 tgtccctgag caaatccact aagagggttg agaaggcttt gctgccacct ggtgtcagcc
1381 tcagtcactt tctctgaatg cttctgagcc ttgcctacat ctctgagcct taactacatg
1441 tctgtgggta tcacactgag tgtgagttgt gtccacacgt gctcaagcag aaggactttt
1501 gtgtccatgc ttgtgtctag aaaacagact ggggaacctt atgtgagcag cacatcccac
1561 cagtgaaaca gggtattgct cttcttcttt tcttgatctt cctgtctggg cagacttcag
1621 agactttgtg gcctggaggc ctattaagca cgacacagta tcagtggaat tgatccataa
1681 acctccctgt ccacatcttg cccaatgggg aatggatctt tcaccaaaga gctcaccagc
1741 attttccaca gagatgcaaa ttctgagccc ttggagttcc cagtggattc aaggaaggaa
1801 gtgggaacaa ggttggatgc ctacttatga gcttgaccat cacagctatc ggtaatcaga
1861 aatatgaaac aaaatctctg cacaaaagag caagctctta agttcacagg gtgcctgggc
1921 tgcatttgaa tatcacttcc cctctgcatt ttcccatcac atagaagact ttgacctgtg
1981 aagctgccat ctgttaatac taaaattccc aaataagaaa aaaaaaaaaa aa
//