LOCUS AF129112 2397 bp mRNA linear HUM 20-APR-1999
DEFINITION Homo sapiens vanilloid receptor-like protein 1 (VRL-1) mRNA,
complete cds.
ACCESSION AF129112
VERSION AF129112.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2397)
AUTHORS Caterina,M.J., Rosen,T.A., Tominaga,M., Brake,A.J. and Julius,D.
TITLE A capsaicin-receptor homologue with a high threshold for noxious
heat
JOURNAL Nature 398 (6726), 436-441 (1999)
PUBMED 10201375
REFERENCE 2 (bases 1 to 2397)
AUTHORS Caterina,M.J., Rosen,T.A., Tominaga,M., Brake,A.J. and Julius,D.
TITLE Direct Submission
JOURNAL Submitted (17-FEB-1999) Cellular and Molecular Pharmacology,
University of California, 513 Parnassus, San Francisco, CA 94143,
USA
FEATURES Location/Qualifiers
source 1..2397
/db_xref="H-InvDB:HIT000070601"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_line="CCRF-CEM"
gene 1..2397
/gene="VRL-1"
CDS 36..2330
/gene="VRL-1"
/codon_start=1
/product="vanilloid receptor-like protein 1"
/protein_id="AAD26363.1"
/translation="MTSPSSSPVFRLETLDGGQEDGSEADRGKLDFGSGLPPMESQFQ
GEDRKFAPQIRVNLNYRKGTGASQPDPNRFDRDRLFNAVSRGVPEDLAGLPEYLSKTS
KYLTDSEYTEGSTGKTCLMKAVLNLKDGVNACILPLLQIDRDSGNPQPLVNAQCTDDY
YRGHSALHIAIEKRSLQCVKLLVENGANVHARACGRFFQKGQGTCFYFGELPLSLAAC
TKQWDVVSYLLENPHQPASLQATDSQGNTVLHALVMISDNSAENIALVTSMYDGLLQA
GARLCPTVQLEDIRNLQDLTPLKLAAKEGKIEIFRHILQREFSGLSHLSRKFTEWCYG
PVRVSLYDLASVDSCEENSVLEIIAFHCKSPHRHRMVVLEPLNKLLQAKWDLLIPKFF
LNFLCNLIYMFIFTAVAYHQPTLKKQAAPHLKAEVGNSMLLTGHILILLGGIYLLVGQ
LWYFWRRHVFIWISFIDSYFEILFLFQALLTVVSQVLCFLAIEWYLPLLVSALVLGWL
NLLYYTRGFQHTGIYSVMIQKVILRDLLRFLLIYLVFLFGFAVALVSLSQEAWRPEAP
TGPNATESVQPMEGQEDEGNGAQYRGILEASLELFKFTIGMGELAFQEQLHFRGMVLL
LLLAYVLLTYILLLNMLIALMSETVNSVATDSWSIWKLQKAISVLEMENGYWWCRKKQ
RAGVMLTVGTKPDGSPDERWCFRVEEVNWASWEQTLPTLCEDPSGAGVPRTLENPVLA
SPPKEDEDGASEENYVPVQLLQSN"
BASE COUNT 494 a 701 c 686 g 516 t
ORIGIN
1 agaggtctgg ctggacgcag cctcctcctc ctaggatgac ctcaccctcc agctctccag
61 ttttcaggtt ggagacatta gatggaggcc aagaagatgg ctctgaggcg gacagaggaa
121 agctggattt tgggagcggg ctgcctccca tggagtcaca gttccagggc gaggaccgga
181 aattcgcccc tcagataaga gtcaacctca actaccgaaa gggaacaggt gccagtcagc
241 cggatccaaa ccgatttgac cgagatcggc tcttcaatgc ggtctcccgg ggtgtccccg
301 aggatctggc tggacttcca gagtacctga gcaagaccag caagtacctc accgactcgg
361 aatacacaga gggctccaca ggtaagacgt gcctgatgaa ggctgtgctg aaccttaagg
421 acggagtcaa tgcctgcatt ctgccactgc tgcagatcga cagggactct ggcaatcctc
481 agcccctggt aaatgcccag tgcacagatg actattaccg aggccacagc gctctgcaca
541 tcgccattga gaagaggagt ctgcagtgtg tgaagctcct ggtggagaat ggggccaatg
601 tgcatgcccg ggcctgcggc cgcttcttcc agaagggcca agggacttgc ttttatttcg
661 gtgagctacc cctctctttg gccgcttgca ccaagcagtg ggatgtggta agctacctcc
721 tggagaaccc acaccagccc gccagcctgc aggccactga ctcccagggc aacacagtcc
781 tgcatgccct agtgatgatc tcggacaact cagctgagaa cattgcactg gtgaccagca
841 tgtatgatgg gctcctccaa gctggggccc gcctctgccc taccgtgcag cttgaggaca
901 tccgcaacct gcaggatctc acgcctctga agctggccgc caaggagggc aagatcgaga
961 ttttcaggca catcctgcag cgggagtttt caggactgag ccacctttcc cgaaagttca
1021 ccgagtggtg ctatgggcct gtccgggtgt cgctgtatga cctggcttct gtggacagct
1081 gtgaggagaa ctcagtgctg gagatcattg cctttcattg caagagcccg caccgacacc
1141 gaatggtcgt tttggagccc ctgaacaaac tgctgcaggc gaaatgggat ctgctcatcc
1201 ccaagttctt cttaaacttc ctgtgtaatc tgatctacat gttcatcttc accgctgttg
1261 cctaccatca gcctaccctg aagaagcagg ccgcccctca cctgaaagcg gaggttggaa
1321 actccatgct gctgacgggc cacatcctta tcctgctagg ggggatctac ctcctcgtgg
1381 gccagctgtg gtacttctgg cggcgccacg tgttcatctg gatctcgttc atagacagct
1441 actttgaaat cctcttcctg ttccaggccc tgctcacagt ggtgtcccag gtgctgtgtt
1501 tcctggccat cgagtggtac ctgcccctgc ttgtgtctgc gctggtgctg ggctggctga
1561 acctgcttta ctatacacgt ggcttccagc acacaggcat ctacagtgtc atgatccaga
1621 aggtcatcct gcgggacctg ctgcgcttcc ttctgatcta cttagtcttc cttttcggct
1681 tcgctgtagc cctggtgagc ctgagccagg aggcttggcg ccccgaagct cctacaggcc
1741 ccaatgccac agagtcagtg cagcccatgg agggacagga ggacgagggc aacggggccc
1801 agtacagggg tatcctggaa gcctccttgg agctcttcaa attcaccatc ggcatgggcg
1861 agctggcctt ccaggagcag ctgcacttcc gcggcatggt gctgctgctg ctgctggcct
1921 acgtgctgct cacctacatc ctgctgctca acatgctcat cgccctcatg agcgagaccg
1981 tcaacagtgt cgccactgac agctggagca tctggaagct gcagaaagcc atctctgtcc
2041 tggagatgga gaatggctat tggtggtgca ggaagaagca gcgggcaggt gtgatgctga
2101 ccgttggcac taagccagat ggcagccccg atgagcgctg gtgcttcagg gtggaggagg
2161 tgaactgggc ttcatgggag cagacgctgc ctacgctgtg tgaggacccg tcaggggcag
2221 gtgtccctcg aactctcgag aaccctgtcc tggcttcccc tcccaaggag gatgaggatg
2281 gtgcctctga ggaaaactat gtgcccgtcc agctcctcca gtccaactga tggcccagat
2341 gcagcaggag gccagaggac agagcagagg atctttccaa ccacatctgc tggctct
//