LOCUS AF128524 3002 bp mRNA linear HUM 20-APR-1999
DEFINITION Homo sapiens sodium-calcium exchanger isoform NCX1.7 precursor
(SLC8A1) mRNA, complete cds.
ACCESSION AF128524
VERSION AF128524.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3002)
AUTHORS Mangini,N.J., Chen,W., Wang,Q. and Kennedy,B.G.
TITLE Na+/Ca2+ exchanger isoforms in cultured human retinal pigment
epithelium
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 3002)
AUTHORS Mangini,N.J. and Chen,W.
TITLE Direct Submission
JOURNAL Submitted (16-FEB-1999) Department of Ophthalmology & Visual
Sciences, University of Illinois at Chicago, College of Medicine,
1855 W. Taylor St., Chicago, IL 60612, USA
FEATURES Location/Qualifiers
source 1..3002
/db_xref="H-InvDB:HIT000070588"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="ncxcln6"
/cell_type="cultured retinal pigment epithelium"
/note="from donor culture YA"
gene 1..3002
/gene="SLC8A1"
/gene_synonym="NCX1"
CDS 23..2905
/gene="SLC8A1"
/gene_synonym="NCX1"
/codon_start=1
/product="sodium-calcium exchanger isoform NCX1.7
precursor"
/protein_id="AAD26362.1"
/translation="MYNMRRLSLSPTFSMGFHLLVTVSLLFSHVDHVIAETEMEGEGN
ETGECTGSYYCKKGVILPIWEPQDPSFGDKIARATVYFVAMVYMFLGVSIIADRFMSS
IEVITSQEKEITIKKPNGETTKTTVRIWNETVSNLTLMALGSSAPEILLSVIEVCGHN
FTAGDLGPSTIVGSAAFNMFIIIALCVYVVPDGETRKIKHLRVFFVTAAWSIFAYTWL
YIILSVISPGVVEVWEGLLTFFFFPICVVFAWVADRRLLFYKYVYKRYRAGKQRGMII
EHEGDRPSSKTEIEMDGKVVNSHVENFLDGALVLEVDERDQDDEEARREMARILKELK
QKHPDKEIEQLIELANYQVLSQQQKSRAFYRIQATRLMTGAGNILKRHAADQARKAVS
MHEVNTEVTENDPVSKIFFEQGTYQCLENCGTVALTIIRRGGDLTNTVFVDFRTEDGT
ANAGSDYEFTEGTVVFKPGDTQKEIRVGIIDDDIFEEDENFLVHLSNVKVSSEASEDG
ILEANHVSTLACLGSPSTATVTIFDDDHAGIFTFEEPVTHVSESIGIMEVKVLRTSGA
RGNVIVPYKTIEGTARGGGEDFEDTCGELEFQNDEIVKIITIRIFDREEYEKECSFSL
VLEEPKWIRRGMKGGFTITGQPVFRKVHAREHPILSTVITIADEYDDKQPLTSKEEEE
RRIAEMGRPILGEHTKLEVIIEESYEFKSTVDKLIKKTNLALVVGTNSWREQFIEAIT
VSAGEDDDDDECGEEKLPSCFDYVMHFLTVFWKVLFAFVPPTEYWNGWACFIVSILMI
GLLTAFIGDLASHFGCTIGLKDSVTAVVFVALGTSVPDTFASKVAATQDQYADASIGN
VTGSNAVNVFLGIGVAWSIAAIYHAANGEQFKVSPGTLAFSVTLFTIFAFINVGVLLY
RRRPEIGGELGGPRTAKLLTSCLFVLLWLLYIFFSSLEAYCHIKGF"
BASE COUNT 821 a 610 c 753 g 818 t
ORIGIN
1 ggttgtgaca gttggaagtg tcatgtacaa catgcggcga ttaagtcttt cacccacctt
61 ttcaatggga tttcatctgt tagttactgt gagtctctta ttttcccatg tggaccatgt
121 aattgctgag acagaaatgg aaggagaagg aaatgaaact ggtgaatgta ctggatcata
181 ttactgtaag aaaggggtga ttttgcccat ttgggaaccc caagaccctt cttttgggga
241 caaaattgct agagctactg tgtattttgt ggccatggtc tacatgtttc ttggagtctc
301 tatcatagct gatcggttca tgtcctctat agaagtcatc acatctcaag aaaaagaaat
361 aaccataaag aaacccaatg gagagaccac caagacaact gtgaggatct ggaatgaaac
421 agtttctaac ctgaccttga tggccctggg atcttctgct cctgagattc tcctttcagt
481 aattgaagtg tgtggccata acttcactgc aggagacctc ggtcctagca ccatcgtggg
541 aagtgctgca ttcaatatgt tcatcattat tgcactctgt gtttatgtgg tgcctgacgg
601 agagacaagg aagattaagc atttgcgtgt cttctttgtg acagcagcct ggagcatctt
661 tgcctacacc tggctttaca ttattttgtc tgtcatatct cctggtgttg tggaggtctg
721 ggaaggtttg cttactttct tcttctttcc catctgtgtt gtgttcgctt gggtagcgga
781 taggagactt ctgttttaca agtatgtcta caagaggtat cgagctggca agcagagggg
841 gatgattatt gaacatgaag gagacaggcc atcttctaag actgaaattg aaatggacgg
901 gaaagtggtc aattctcatg ttgaaaattt cttagatggt gctctggttc tggaggtgga
961 tgagagggac caagatgatg aagaagctag gcgagaaatg gctaggattc tgaaggaact
1021 taagcagaag catccagata aagaaataga gcaattaata gaattagcta actaccaagt
1081 cctaagtcag cagcaaaaaa gtagagcatt ttatcgcatt caagctactc gcctcatgac
1141 tggagctggc aacattttaa agaggcatgc agctgaccaa gcaaggaagg ctgtcagcat
1201 gcacgaggtc aacactgaag tgactgaaaa tgaccctgtt agtaagatct tctttgaaca
1261 agggacatat cagtgtctgg agaactgtgg tactgtggcc cttaccatta tccgcagagg
1321 tggtgatttg actaacactg tgtttgttga cttcagaaca gaggatggca cagcaaatgc
1381 tgggtctgat tatgaattta ctgaaggaac tgtggtgttt aagcctggtg atacccagaa
1441 ggaaatcaga gtgggtatca tagatgatga tatctttgag gaggatgaaa atttccttgt
1501 gcatctcagc aatgtcaaag tatcttctga agcttcagaa gatggcatac tggaagccaa
1561 tcatgtttct acacttgctt gcctcggatc tccctccact gccactgtaa ctatttttga
1621 tgatgaccac gcaggcattt ttacttttga ggaacctgtg actcatgtga gtgagagcat
1681 tggcatcatg gaggtgaaag tattgagaac atctggagct cgaggaaatg ttatcgttcc
1741 atataaaacc atcgaaggga ctgccagagg tggaggggag gattttgagg acacttgtgg
1801 agagctcgaa ttccagaatg atgaaattgt gaagatcatt accattagaa tatttgaccg
1861 tgaggaatat gagaaagagt gcagtttctc ccttgtgctt gaggaaccaa aatggataag
1921 aagaggaatg aaaggtggct tcacaataac aggccaacct gtcttcagga aggttcatgc
1981 tagagaacat ccgattctct ctactgtaat caccattgca gacgaatatg atgacaagca
2041 gccactgacc agcaaagagg aagaggagag gcgcattgca gaaatggggc gccccatcct
2101 gggagagcac accaagttgg aagtgatcat tgaagaatcc tatgaattca agagtactgt
2161 ggacaaactc attaagaaga caaacctggc ccttgtggtt gggactaaca gctggagaga
2221 acagttcatt gaagctatca ctgtcagtgc tggggaagat gatgacgacg atgaatgtgg
2281 ggaagagaag ctgccctcct gtttcgatta cgtgatgcac tttctgactg tgttctggaa
2341 ggtcctgttt gccttcgtcc cccctactga atactggaat ggctgggcgt gtttcattgt
2401 ctccatcctc atgattggcc tactgacagc tttcattgga gacctggctt cccactttgg
2461 ctgcaccatt ggcctgaaag attctgtgac tgcagtcgtg ttcgtcgcac ttggaacatc
2521 agtgccagac acatttgcca gcaaagtggc agccacccag gaccagtatg cagacgcctc
2581 cataggtaac gtcacgggca gcaacgcggt gaatgtcttc ctgggaatcg gtgtggcctg
2641 gtccatcgct gccatctacc acgcagccaa tggggaacag ttcaaagtgt cccctggcac
2701 actagctttc tctgtcactc tcttcaccat ttttgctttc atcaatgtgg gggtgctgct
2761 gtatcggcgg aggccagaaa tcggaggtga gctgggtggg ccccggactg ccaagctcct
2821 cacatcctgc ctctttgtgc tcctatggct cttgtacatt ttcttctcct ccctggaggc
2881 ctactgccac ataaaaggct tctaaaggaa ctatcagata tagtaaattt atatatatac
2941 atatatatac ataaaaatta tgtataatgg acagaggaaa ctgacaaatc actagtgaat
3001 tc
//