LOCUS AF127763 2609 bp mRNA linear HUM 29-OCT-1999
DEFINITION Homo sapiens mitogenic oxidase mRNA, complete cds.
ACCESSION AF127763
VERSION AF127763.2
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2609)
AUTHORS Suh,Y.A., Arnold,R.S., Lassegue,B., Shi,J., Xu,X., Sorescu,D.,
Chung,A.B., Griendling,K.K. and Lambeth,J.D.
TITLE Cell transformation by the superoxide-generating oxidase Mox1
JOURNAL Nature 401 (6748), 79-82 (1999)
PUBMED 10485709
REFERENCE 2 (bases 1 to 2609)
AUTHORS Suh,Y.-A., Arnold,R.S., Shi,J., Murad,E. and Lambeth,J.D.
TITLE Direct Submission
JOURNAL Submitted (11-FEB-1999) Biochemistry, Emory University, 1510
Clifton Rd., Atlanta, GA 30322, USA
REFERENCE 3 (bases 1 to 2609)
AUTHORS Suh,Y.-A., Arnold,R.S., Shi,J., Murad,E. and Lambeth,J.D.
TITLE Direct Submission
JOURNAL Submitted (29-OCT-1999) Biochemistry, Emory University, 1510
Clifton Rd., Atlanta, GA 30322, USA
REMARK Sequence update by submitter
COMMENT On Oct 29, 1999 this sequence version replaced AF127763.1.
FEATURES Location/Qualifiers
source 1..2609
/db_xref="H-InvDB:HIT000070572"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/tissue_type="colon epithelium"
CDS 207..1901
/note="Mox1; similar to gp91phox; putative pyridine
nucleotide-dependent superoxide-generating protein"
/codon_start=1
/product="mitogenic oxidase"
/protein_id="AAD38133.1"
/translation="MGNWVVNHWFSVLFLVVWLGLNVFLFVDAFLKYEKADKYYYTRK
ILGSTLACARASALCLNFNSTLILLPVCRNLLSFLRGTCSFCSRTLRKQLDHNLTFHK
LVAYMICLHTAIHIIAHLFNFDCYSRSRQATDGSLASILSSLSHDEKKGGSWLNPIQS
RNTTVEYVTFTSVAGLTGVIMTIALILMVTSATEFIRRSYFEVFWYTHHLFIFYILGL
GIHGIGGIVRGQTEESMNESHPRKCAESFEMWDDRDSHCRRPKFEGHPPESWKWILAP
VILYICERILRFYRSQQKVVITKVVMHPSKVLELQMNKRGFSMEVGQYIFVNCPSISL
LEWHPFTLTSAPEEDFFSIHIRAAGDWTENLIRAFEQQYSPIPRIEVDGPFGTASEDV
FQYEVAVLVGAGIGVTPFASILKSIWYKFQCADHNLKTKKIYFYWICRETGAFSWFNN
LLTSLEQEMEELGKVGFLNYRLFLTGWDSNIVGHAALNFDKATDIVTGLKQKTSFGRP
MWDNEFSTIATSHPKSVVGVFLCGPRTLAKSLRKCCHRYSSLDPRKVQFYFNKENF"
BASE COUNT 703 a 574 c 549 g 779 t
ORIGIN
1 gctgatagca cagttctgtc cagagaagga aggcggaata aacttattca ttcccaggaa
61 ctcttggggt aggtgtgtgt ttttcacatc ttaaaggctc acagaccctg cgctggacaa
121 atgttccatt cctgaaggac ctctccagaa tccggattgc tgaatcttcc ctgttgccta
181 gaagggctcc aaaccacctc ttgacaatgg gaaactgggt ggttaaccac tggttttcag
241 ttttgtttct ggttgtttgg ttagggctga atgttttcct gtttgtggat gccttcctga
301 aatatgagaa ggccgacaaa tactactaca caagaaaaat ccttgggtca acattggcct
361 gtgcccgagc gtctgctctc tgcttgaatt ttaacagcac gctgatcctg cttcctgtgt
421 gtcgcaatct gctgtccttc ctgaggggca cctgctcatt ttgcagccgc acactgagaa
481 agcaattgga tcacaacctc accttccaca agctggtggc ctatatgatc tgcctacata
541 cagctattca catcattgca cacctgttta actttgactg ctatagcaga agccgacagg
601 ccacagatgg ctcccttgcc tccattctct ccagcctatc tcatgatgag aaaaaggggg
661 gttcttggct aaatcccatc cagtcccgaa acacgacagt ggagtatgtg acattcacca
721 gcgttgctgg tctcactgga gtgatcatga caatagcctt gattctcatg gtaacttcag
781 ctactgagtt catccggagg agttattttg aagtcttctg gtatactcac caccttttta
841 tcttctatat ccttggctta gggattcacg gcattggtgg aattgtccgg ggtcaaacag
901 aggagagcat gaatgagagt catcctcgca agtgtgcaga gtcttttgag atgtgggatg
961 atcgtgactc ccactgtagg cgccctaagt ttgaagggca tccccctgag tcttggaagt
1021 ggatccttgc accggtcatt ctttatatct gtgaaaggat cctccggttt taccgctccc
1081 agcagaaggt tgtgattacc aaggttgtta tgcacccatc caaagttttg gaattgcaga
1141 tgaacaagcg tggcttcagc atggaagtgg ggcagtatat ctttgttaat tgcccctcaa
1201 tctctctcct ggaatggcat ccttttactt tgacctctgc tccagaggaa gatttcttct
1261 ccattcatat ccgagcagca ggggactgga cagaaaatct cataagggct ttcgaacaac
1321 aatattcacc aattcccagg attgaagtgg atggtccctt tggcacagcc agtgaggatg
1381 ttttccagta tgaagtggct gtgctggttg gagcaggaat tggggtcacc ccctttgctt
1441 ctatcttgaa atccatctgg tacaaattcc agtgtgcaga ccacaacctc aaaacaaaaa
1501 agatctattt ctactggatc tgcagggaga caggtgcctt ttcctggttc aacaacctgt
1561 tgacttccct ggaacaggag atggaggaat taggcaaagt gggttttcta aactaccgtc
1621 tcttcctcac cggatgggac agcaatattg ttggtcatgc agcattaaac tttgacaagg
1681 ccactgacat cgtgacaggt ctgaaacaga aaacctcctt tgggagacca atgtgggaca
1741 atgagttttc tacaatagct acctcccacc ccaagtctgt agtgggagtt ttcttatgtg
1801 gccctcggac tttggcaaag agcctgcgca aatgctgtca ccgatattcc agtctggatc
1861 ctagaaaggt tcaattctac ttcaacaaag aaaatttttg agttatagga ataaggacgg
1921 taatctgcat tttgtctctt tgtatcttca gtaattgagt tataggaata aggacggtaa
1981 tctgcatttt gtctctttgt atcttcagta atttacttgg tctcntcagg tttgancagt
2041 cactttagga taagaatgtg cctctcaagc cttgactccc tggtattctt tttttgattg
2101 cattcaactt cgttacttga gcttcagcaa cttaagaact tctgaagttc ttaaagttct
2161 gaanttctta aagcccatgg atcctttctc agaaaaataa ctgtaaatct ttctggacag
2221 ccatgactgt agcaaggctt gatagcagaa gtttggtggt tcanaattat acaactaatc
2281 ccaggtgatt ttatcaattc cagtgttacc atctcctgag ttttggtttg taatcttttg
2341 tccctcccac ccccacagaa gattttaagt agggtgactt tttaaataaa aatttattga
2401 ataattaatg ataaaacata ataataaaca taaataataa acaaaattac cgagaacccc
2461 atccccatat aacaccaaca gtgtacatgt ttactgtcac ttttgatatg gtttatccag
2521 tgtgaacagc aatttattat ttttgctcat caaaaaataa aggatttttt ttcacttgaa
2581 aaaaaaaaaa aaaaaaaaaa aaaaaaaaa
//