LOCUS AF126162 2406 bp mRNA linear HUM 31-AUG-1999
DEFINITION Homo sapiens HERV-H LTR associated protein 2 (HHLA2) mRNA, complete
cds.
ACCESSION AF126162
VERSION AF126162.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2406)
AUTHORS Mager,D.L., Hunter,D.G., Schertzer,M. and Freeman,J.D.
TITLE Endogenous retroviruses provide the primary polyadenylation signal
for two new human genes (HHLA2 and HHLA3)
JOURNAL Genomics 59 (3), 255-263 (1999)
PUBMED 10444326
REFERENCE 2 (bases 1 to 2406)
AUTHORS Mager,D.L. and Freeman,J.D.
TITLE Direct Submission
JOURNAL Submitted (04-FEB-1999) Terry Fox Laboratory, B.C. Cancer Agency,
601 West 10th Avenue, Vancouver, BC V5Z1L3, Canada
FEATURES Location/Qualifiers
source 1..2406
/db_xref="H-InvDB:HIT000070532"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
gene 1..2406
/gene="HHLA2"
/note="HERV-H LTR associating gene 2"
CDS 155..1399
/gene="HHLA2"
/note="immunoglobulin superfamily member"
/codon_start=1
/product="HERV-H LTR associating protein 2"
/protein_id="AAD48396.1"
/translation="MKAQTALSFFLILITSLSGSQGIFPLAFFIYVPMNEQIVIGRLD
EDIILPSSFERGSEVVIHWKYQDSYKVHSYYKGSDHLESQDPRYANRTSLFYNEIQNG
NASLFFRRVSLLDEGIYTCYVGTAIQVITNKVVLKVGVFLTPVMKYEKRNTNSFLICS
VLSVYPRPIITWKMDNTPISENNMEETGSLDSFSINSPLNITGSNSSYECTIENSLLK
QTWTGRWTMKDGLHKMQSEHVSLSCQPVNDYFSPNQDFKVTWSRMKSGTFSVLAYYLS
SSQNTIINESRFSWNKELINQSDFSMNLMDLNLSDSGEYLCNISSDEYTLLTIHTVHV
EPSQETASHNKGLWILVPSAILAAFLLIWSVKCCRAQLEARRSRHPADGAQQERCCVP
PGERCPSAPDNGEENVPLSGKV"
repeat_region 1985..2400
/note="HERV-H endogenous retroviral LTR"
/rpt_type=long_terminal_repeat
regulatory 2379..2385
/regulatory_class="polyA_signal_sequence"
/gene="HHLA2"
BASE COUNT 749 a 534 c 463 g 660 t
ORIGIN
1 agtttactct acatcatagc agagaaaatg gacaaaacac agctgttttg catgtaggag
61 aatactaacc ctgcacagat tgtgatggtg atgtggaata tactaaagcc tagaacgcac
121 ctcctctgca tgactaatat gttctgcaca agacatgaag gcacagacag cactgtcttt
181 cttcctcatt ctcataacat ctctgagtgg atctcaaggc atattccctt tggctttctt
241 catttatgtt cctatgaatg aacaaatcgt cattggaaga cttgatgaag atataattct
301 cccttcttca tttgagaggg gatccgaagt cgtaatacac tggaagtatc aagatagcta
361 taaggttcac agttactaca aaggcagtga ccatttggaa agccaagatc ccagatatgc
421 aaacaggaca tcccttttct ataatgagat tcaaaatggg aatgcgtcgc tatttttcag
481 aagagtaagc cttctggacg aaggaattta cacctgctat gtaggaacag caattcaagt
541 gattacaaac aaagtggtgc taaaggtggg agtttttctc acacccgtga tgaagtatga
601 aaagaggaac acaaacagct tcttaatatg cagcgtgtta agtgtttatc ctcgtccaat
661 tatcacgtgg aaaatggaca acacacctat ctctgaaaac aacatggaag aaacagggtc
721 tttggattct ttttctatta acagcccact gaatattaca ggatcaaatt catcttatga
781 atgtacaatt gaaaattcac tgctgaagca aacatggaca gggcgctgga cgatgaaaga
841 tggccttcat aaaatgcaaa gtgaacacgt ttcactctca tgtcaacctg taaatgatta
901 tttttcacca aaccaagact tcaaagttac ttggtccaga atgaaaagtg ggactttctc
961 tgtcctggct tactatctga gctcctcaca aaatacaatt atcaatgaat cccgattctc
1021 atggaacaaa gagctgataa accagagtga cttctctatg aatttgatgg atcttaatct
1081 ttcagacagt ggggaatatt tatgcaatat ttcttcggat gaatatactt tacttaccat
1141 ccacacagtg catgtagaac cgagccaaga aacagcttcc cataacaaag gcttatggat
1201 tttggtgccc tctgcgattt tggcagcttt tctgctgatt tggagcgtaa aatgttgcag
1261 agcccagcta gaagccagga ggagcagaca ccctgctgat ggagcccaac aagaaagatg
1321 ttgtgtccct cctggtgagc gctgtcccag tgcacccgat aatggcgaag aaaatgtgcc
1381 tctttcagga aaagtatagg aaatgagaga agactgtgac aactcatgac ctgcatcctt
1441 aatatccagt gacttcatct cccctttctt caccacaatt ccaggcaatg gcctgtcgga
1501 ccagacaatt ctaccactgc aaagagttgt aaccattttc tggtatcaca tttatttttc
1561 aagacatact tttcaagaca tcattcactg acccactacc tgcattgagt ataaatgcct
1621 ggatgttaag gattccaatt taactttgaa aagaactgtc tcattcattt acatttctgt
1681 tacagtcagc ccaggaggtt acagtgagct ctccactaag aatctggaag aaatgcatca
1741 ctaggggttg attcccaatc tgatcaactg ataatgggtg agagagcagg taagagccaa
1801 agtcacctta gtggaaaggt taaaaaccag agcctggaaa ccaagatgat tgatttgaca
1861 aggtatttta gtctagtttt atatgaacgg ttgtatcagg gtaaccaact cgatttggga
1921 tgaatcttag ggcaccaaag actaagacag tatctttaag attgctaggg aaaagggccc
1981 tatgtgtcag gcctctgagc ccaagccaag catcgcatcc cctgtgattt gcacgtatac
2041 atccagatgg cctaaagtaa ctgaagatcc acaaaagaag taaaaatagc cttaactgat
2101 gacattccac cattgtgatt tgttcctgcc ccaccctaac tgatcaatgt actttgtaat
2161 ctcccccacc cttaagaagg tactttgtaa tcttccccac ccttaagaag gttctttgta
2221 attctcccca cccttgagaa tgtactttgt gagatccacc ctgcccacaa aacattgctc
2281 ttaacttcac cgcctaaccc aaaacctata agaactaatg ataatccatc acccttcgct
2341 gactctcttt tcggactcag cccacctgca cccaggtgaa ataaacagct ttattgctca
2401 aaaaaa
//