LOCUS AF125349 1939 bp mRNA linear HUM 01-FEB-2000
DEFINITION Homo sapiens guanine nucleotide exchange factor cytohesin-4p mRNA,
complete cds.
ACCESSION AF125349
VERSION AF125349.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1939)
AUTHORS Ogasawara,M., Kim,S.C., Adamik,R., Togawa,A., Ferrans,V.J.,
Takeda,K., Kirby,M., Moss,J. and Vaughan,M.
TITLE Similarities in function and gene structure of cytohesin-4 and
cytohesin-1, guanine nucleotide-exchange proteins for
ADP-ribosylation factors
JOURNAL J. Biol. Chem. 275 (5), 3221-3230 (2000)
PUBMED 10652308
REFERENCE 2 (bases 1 to 1939)
AUTHORS Ogasawara,M., Kim,S.-C., Adamik,R., Togawa,A., Moss,M. and
Vaughan,M.
TITLE Direct Submission
JOURNAL Submitted (01-FEB-1999) Pulmonary Critical Care Medicine Branch,
NHLBI, NIH, Center Drive, Bethesda, MD 20892, USA
FEATURES Location/Qualifiers
source 1..1939
/db_xref="H-InvDB:HIT000070512"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="22"
CDS 188..1372
/note="cytohesin-4; similar to cytohesin-1 (B2-1) and
yeast Sec7 proteins"
/codon_start=1
/product="guanine nucleotide exchange factor cytohesin-4p"
/protein_id="AAF28896.1"
/translation="MDLCHPEPAELSSGETEELQRIKWHRKQLLEDIQKLKDEIADVF
AQIDCFESAEESRMAQKEKELCIGRKKFNMDPAKGIQYFIEHKLLTPDVQDIARFLYK
GEGLNKTAIGTYLGERDPINLQVLQAFVDCHEFANLNLVQALRQFLWSFRLPGEAQKI
DRMMEAFATRYCLCNPGVFQSTDTCYVLSFSIIMLNTSLHNPNVRDRPPFERFVSMNR
GINNGSDLPEDQLRNLFDSIKSEPFSIPEDDGNDLTHTFFNPDREGWLLKLGGRVKTW
KRRWFILTDNCLYYFEFTTDKEPRGIIPLENLSVQKVDDPKKPFCLELYNPSCRGQKI
KACKTDGDGRVVEGKHESYRISATSAEERDQWIESIRASITRVPFYDLVSTRKKKIAS
KQ"
BASE COUNT 430 a 598 c 559 g 352 t
ORIGIN
1 tgtcaaaagc ctgcacacga gacccccgtg ggccaggact gacttcctcc ccacacaggg
61 ctgggcgggg caagcaggaa ggagcctgtt acagtcaagg tgacgcatcc ttgccgggcc
121 agcccgaaca gcagctgggt cggcaagcga caggagcacg ggtcatcttt tccccagagg
181 cgtcggaatg gacctgtgcc acccagagcc cgcggagctg agcagcgggg agacggaaga
241 gttacagagg atcaagtggc accgaaagca gctcctggag gacatccaga agctgaagga
301 tgagattgca gatgtgtttg cccaaatcga ctgcttcgag agtgcggagg agagccggat
361 ggcccagaag gagaaggagc tgtgtattgg gcgcaagaag ttcaacatgg accccgccaa
421 gggtatccag tatttcattg agcacaagct gctgacccct gacgtccagg acattgcacg
481 gttcctgtat aaaggcgagg gcctcaacaa gacagccatt ggtacctacc tgggggagag
541 ggatcccatc aacctgcagg tcctccaggc cttcgtggac tgccacgagt tcgccaacct
601 caacctcgtc caggccctca ggcagttcct gtggagcttc cggctgccgg gcgaggccca
661 gaagatagac cggatgatgg aggcctttgc cactcgatac tgcctctgca acccaggcgt
721 cttccagtcc acagacacct gctacgtgtt gtccttctcc atcatcatgc tcaacaccag
781 cctccacaat cccaacgtcc gggacaggcc gccttttgag cgctttgtgt ccatgaaccg
841 cggcatcaac aatggtagcg acctgcccga ggaccagctg cggaacctct tcgacagcat
901 caagagtgag ccattctcca tccctgagga cgacggcaat gacctcactc acaccttctt
961 caatccagac cgggagggtt ggctgctcaa gctagggggc cgcgtgaaga cgtggaaacg
1021 gcgctggttc atcctgaccg acaactgcct ctactacttc gagttcacca ctgacaagga
1081 gccacgggga attatacctc ttgagaacct ctcggtgcag aaggtggatg accccaagaa
1141 gccattctgc ctggagctct acaaccctag ctgccgaggc cagaaaatca aggcctgcaa
1201 gaccgatggc gacggcaggg tggtggaggg caagcacgaa tcgtaccgca tctcagccac
1261 cagtgccgag gaacgtgacc agtggatcga gtccatccga gccagcatca cccgtgtccc
1321 cttctacgac ctggtctcta ctcggaagaa gaagattgcc agcaagcagt gagattcctg
1381 gaggtggcac ccagtgcact cttttgggcc acagacatca ttgctgttcc ccgttacctc
1441 gagctgactc tagaggggaa ggcagagctc aggagggtgg gtgggagctg cagtgggctc
1501 agagtccagc aatgaggccc cctggcctgg gcacccagct gcaggcccct gccctacgtg
1561 cactacagga aggggtgagg agagcagcca gaggaaaacc agccccagaa tgctgcaact
1621 tctcttctct ctggacttcg gtgtcctcgg ctctgaaggc gctctctgca cttagatgct
1681 gtcagccctc aacgtaggag gggccgtggg gtccctaagt gattcttctc cctggcaagg
1741 ctcttccttt tcagggatat ctctgccaac ccctcccctg tcctcgggtt gggcttggcc
1801 ctctctgcct gagagagctc agcacacaca cagctcagac ccacggacag gaccccggga
1861 cagaaccccg ggagcactgc cctaggagcc cggaccccac gagctcagtc ccagctctgc
1921 ctctgactcg ctgtgtgcc
//