LOCUS AF125188 1578 bp mRNA linear HUM 11-AUG-1999
DEFINITION Homo sapiens adenosine deaminase acting on tRNA 1 (hADAT1) mRNA,
complete cds.
ACCESSION AF125188
VERSION AF125188.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1578)
AUTHORS Maas,S., Gerber,A.P. and Rich,A.
TITLE Identification and characterization of a human tRNA-specific
adenosine deaminase related to the ADAR family of pre-mRNA editing
enzymes
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 96 (16), 8895-8900 (1999)
PUBMED 10430867
REFERENCE 2 (bases 1 to 1578)
AUTHORS Maas,S.
TITLE Direct Submission
JOURNAL Submitted (01-FEB-1999) Department of Biology, MIT, 31 Ames Street,
Cambridge, MA 02141, USA
FEATURES Location/Qualifiers
source 1..1578
/db_xref="H-InvDB:HIT000070503"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/tissue_type="brain"
gene 1..1578
/gene="hADAT1"
CDS 50..1558
/gene="hADAT1"
/note="ADAR-related protein; tRNA-specific adenosine
deaminase"
/codon_start=1
/product="adenosine deaminase acting on tRNA 1"
/protein_id="AAD48376.1"
/translation="MWTADEIAQLCYEHYGIRLPKKGKPEPNHEWTLLAAVVKIQSPA
DKACDTPDKPVQVTKEIVSMGTGTKCIGQSKMRKNGDILNDSHAEVIARRSFQRYLLH
QLQLAATLKEDSIFVPGTQKGVWKLRRDLIFVFFSSHTPCGDASIIPMLEFEDQPCCP
VFRNWANNSSVEASSNLEAPGNERKCEDPDSPVTKKMRLEPGTAAREVTNGAAHHQSF
GKQKSGPISPGIHSCDLTVEGLATVTRIAPGSAKVTDVYRTGAKCVPGEAGDSGKPGA
AFHQVGLLRVKPGRGDRTRSMSCSDKMARWNVLGCQGALLMHLLEEPIYLSAVVIGKC
PYSQEAMQRALIGRCQNVSALPKGFGVQELKILQSDLLFEQSRSAVQAKRADSPGRLV
PCGAAISWSAVPEQPLDVTANGFPQGTTKKTIGSLQARSQISKVELFRSFQKLLSRIA
RDKWPHSLRVQKLDTYQEYKEAASSYQEAWSTLRKQVFGSWIRNPPDYHQFK"
BASE COUNT 448 a 377 c 428 g 325 t
ORIGIN
1 ccttgtgatg cctccctaga aatgagaggt ctcaatacca gctcagacca tgtggaccgc
61 ggatgagatt gctcagctat gctatgaaca ctatgggatc aggctgccca agaaggggaa
121 gcctgagcca aaccatgagt ggacattatt ggcagcggtg gtgaagatac aatctccagc
181 tgacaaggcc tgcgacaccc ctgataagcc ggtgcaagtg acaaaggaaa ttgtgtcaat
241 gggaacagga acaaaatgca taggacagtc caaaatgagg aagaacggag acatcctcaa
301 tgatagccat gctgaggtca tagccagaag gagtttccaa aggtaccttc tccaccaact
361 ccagttggca gccaccctga aagaggatag catctttgtc ccaggaactc aaaaaggagt
421 gtggaaactt agacgagacc tcatttttgt gtttttctcc agccatacac cctgtgggga
481 tgcctccatc attccgatgc ttgagtttga agatcagcct tgctgtcctg tcttcagaaa
541 ttgggccaac aactcatcag tagaagccag tagtaacctg gaagctcctg gaaatgaaag
601 aaaatgtgaa gaccctgaca gtcctgtaac caaaaagatg aggcttgagc ctgggactgc
661 agccagggag gtcaccaacg gagcagctca ccatcagagt tttggcaagc agaaaagtgg
721 cccaatctca ccaggcatcc acagctgtga tctcactgta gagggactgg ctactgtcac
781 cagaatagcc cctggtagtg ccaaagtgac agacgtttat agaactggag ccaagtgtgt
841 acctggagaa gctggagact ccggaaagcc gggtgctgcg tttcaccagg tggggctgct
901 ccgagtgaag ccaggccgtg gagacagaac acgctccatg tcctgtagtg acaagatggc
961 ccgatggaac gtcctcggat gccaaggggc actgttgatg cacttgctgg aagagcccat
1021 ctacctgtca gctgtggtca ttgggaagtg cccatacagc caggaagcca tgcagagagc
1081 actgattgga aggtgtcaga atgtgtctgc tttaccaaaa ggcttcggag ttcaagaatt
1141 aaaaatactg cagtcagatt tactatttga acagagccgc agtgcggtgc aggcaaaaag
1201 ggctgatagc ccaggtcgac ttgttccttg tggggcagcc atcagctgga gtgcagttcc
1261 tgagcagcct ttggatgtta ctgccaatgg ctttccacag ggaacaacaa agaaaacaat
1321 tggaagcctt caggcaagat cccaaatcag caaagtggaa ctcttcagat cattccagaa
1381 gctgctaagc agaattgcaa gggacaagtg gccacactcc ctcagggtgc agaagctgga
1441 tacctaccag gagtacaagg aggctgcgtc ctcttaccag gaagcctgga gcacactccg
1501 gaagcaggtg tttggatcct ggatcagaaa cccaccggat tatcaccagt tcaagtgaga
1561 aggaaatgtt tgctctgg
//