LOCUS AF125158 3029 bp mRNA linear HUM 18-NOV-1999
DEFINITION Homo sapiens zinc finger DNA binding protein 99 (ZNF281) mRNA,
complete cds.
ACCESSION AF125158
VERSION AF125158.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3029)
AUTHORS Law,D.J., Du,M., Law,G.L. and Merchant,J.L.
TITLE ZBP-99 defines a conserved family of transcription factors and
regulates ornithine decarboxylase gene expression
JOURNAL Biochem. Biophys. Res. Commun. 262 (1), 113-120 (1999)
PUBMED 10448078
REFERENCE 2 (bases 1 to 3029)
AUTHORS Law,D.J., Law,G.L., Morris,D.R. and Merchant,J.L.
TITLE Direct Submission
JOURNAL Submitted (01-FEB-1999) Howard Hughes Medical Institute, University
of Michigan, 1150 West Medical Center Drive, Ann Arbor, MI
48109-0650, USA
FEATURES Location/Qualifiers
source 1..3029
/db_xref="H-InvDB:HIT000070500"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="1"
/map="1q32.1"
/cell_line="Jurkat T-cell leukemia"
gene 1..3029
/gene="ZNF281"
CDS 24..2711
/gene="ZNF281"
/function="represses gastrin and ornithine decarboxylase
gene expression"
/note="transcription factor ZBP-99; 99 kDa"
/codon_start=1
/product="zinc finger DNA binding protein 99"
/protein_id="AAD21084.1"
/translation="MKIGSGFLSGGGGTGSSGGSGSGGGGSGGGGGGGSSGRRAEMEP
TFPQGMVMFNHRLPPVTSFTRPAGSAAPPPQCVLSSSTSAAPAAEPPPPPAPDMTFKK
EPAASAAAFPSQRTSWGFLQSLVSIKQEKPADPEEQQSHHHHHHHHYGGLFAGAEERS
PGLGGGEGGSHGVIQDLSILHQHVQQQPAQHHRDVLLSSSSRTDDHHGTEEPKQDTNV
KKAKRPKPESQGIKAKRKPSASSKPSLVGDGEGAILSPSQKPHICDHCSAAFRSSYHL
RRHVLIHTGERPFQCSQCSMGFIQKYLLQRHEKIHSREKPFGCDQCSMKFIQKYHMER
HKRTHSGEKPYKCDTCQQYFSRTDRLLKHRRTCGEVIVKGATSAEPGSSNHTNMGNLA
VLSQGNTSSSRRKTKSKSIAIENKEQKTGKTNESQISNNINMQSYSVEMPTVSSSGGI
IGTGIDELQKRVPKLIFKKGSRKNTDKNYLNFVSPLPDIVGQKSLSGKPSGSLGIVSN
NSVETIGLLQSTSGKQGQISSNYDDAMQFSKKRRYLPTASSNSAFSINVGHMVSQQSV
IQSAGVSVLDNEAPLSLIDSSALNAEIKSCHDKSGIPDEVLQSILDQYSNKSESQKED
PFNIAEPRVDLHTSGEHSELVQEENLSPGTQTPSNDKASMLQEYSKYLQQAFEKSTNA
SFTLGHGFQFVSLSSPLHNHTLFPEKQIYTTSPLECGFGQSVTSVLPSSLPKPPFGML
FGSQPGLYLSALDATHQQLTPSQELDDLIDSQKNLETSSAFQSSSQKLTSQKEQKNLE
SSTGFQIPSQELASQIDPQKDIEPRTTYQIENFAQAFGSQFKSGSRVPMTFITNSNGE
VDHRVRTSVSDFSGYTNMMSDVSEPCSTRVKTPTSQSYR"
BASE COUNT 917 a 690 c 693 g 729 t
ORIGIN
1 ggcacgagcg cctcctccgg ggtatgaaaa tcggcagtgg gttcctgagt ggcggcggag
61 gtaccggcag tagcggtggt agcggctccg gcggcggtgg tagtggcggc ggcggcggcg
121 gcggcagcag cggcaggagg gcagagatgg aacccacctt tccccagggt atggttatgt
181 tcaaccaccg tcttcccccg gtcaccagct tcacccggcc ggcggggtcg gccgcccctc
241 ccccgcaatg cgtgttatcc tcctctacct ccgcagcccc ggccgctgag cccccccctc
301 cgccagcccc ggacatgact ttcaagaagg agccggcggc gtcagccgcg gccttcccct
361 cgcagaggac ctcctggggg ttcttgcagt ctttggttag catcaaacag gagaaacccg
421 cggatcctga ggagcagcag tcccaccacc accatcacca ccaccactat ggggggctgt
481 tcgctggagc tgaagagagg tctccaggcc taggaggcgg tgaagggggg agtcacggcg
541 tcatccagga cctcagtatt ctccaccagc atgtccagca gcaaccagcc cagcaccacc
601 gtgacgtatt actcagcagc agtagcagga ctgatgacca ccatggcact gaggagccaa
661 agcaggacac taatgtcaaa aaggcaaaaa ggccaaagcc agaatctcag ggaatcaaag
721 ccaagaggaa gccaagtgca tcttccaaac cttctttggt tggagatgga gaaggtgcca
781 tcctctcccc aagtcagaaa cctcatatct gtgatcactg tagtgctgct ttccgaagct
841 cctatcacct gcggagacat gtcctcattc atacaggaga aagacctttc cagtgcagcc
901 agtgtagtat gggtttcatt cagaaatacc tactacagag acatgagaaa attcatagta
961 gagagaagcc atttggatgt gatcagtgca gcatgaagtt tattcagaag taccatatgg
1021 agagacacaa gaggacacat agtggagaaa agccatataa gtgtgacact tgccaacagt
1081 atttttcaag gactgataga ttgttgaagc acaggcgcac atgtggtgaa gtcatagtta
1141 aaggagccac tagtgcagaa cctgggtcat caaaccatac caatatgggt aatctggctg
1201 tgttgtctca gggaaataca agttcttcaa ggagaaaaac aaagtcaaaa agcatagcta
1261 ttgaaaataa ggaacagaag accggtaaaa caaatgaatc gcaaatttca aataatataa
1321 acatgcagag ttactcagta gaaatgccta ccgtgtcttc cagtggaggc ataattggca
1381 ctggaataga tgaactgcag aagagggtgc caaaattgat ctttaagaaa ggaagcagaa
1441 agaatacaga taaaaactac cttaactttg tgtcaccatt accagacata gtaggacaga
1501 aatccttgtc tggaaaacca agtggctcac ttggcatagt atcaaataat agtgtggaga
1561 ccattggtct tctccaaagt acaagtggca aacaaggtca gataagtagt aattatgatg
1621 atgccatgca gttttcaaag aaaagaagat atttaccaac tgccagcagc aacagtgcct
1681 tttctataaa cgtaggacac atggtctccc aacagtctgt cattcagtct gcaggtgtca
1741 gtgttttgga caatgaggca ccattgtcac ttattgactc ctcagctcta aatgctgaaa
1801 ttaaatcttg tcatgacaag tctggaattc ctgatgaggt tttacaaagt attttggatc
1861 aatactccaa caaatcagaa agccagaaag aggatccttt caatattgca gaaccacgag
1921 tggatttaca cacctcagga gaacactcag aattggttca agaagaaaat ttgagcccag
1981 gcacccaaac accttcaaat gataaagcaa gtatgttgca agaatactcc aaatacctcc
2041 aacaggcttt tgaaaaatcc actaatgcaa gttttactct tggacacggt ttccaatttg
2101 tcagtttgtc ttcacctctc cacaaccaca ctttgtttcc agaaaaacaa atatacacta
2161 cgtctccttt ggagtgtggt ttcggccaat ctgttacctc agtgttgcca tcttcattgc
2221 caaagcctcc ttttgggatg ttgtttggat ctcagccagg tctttatttg tctgctttgg
2281 atgctacaca tcagcagttg acaccttccc aggagctgga tgatctgata gattctcaga
2341 agaacttaga gacttcatca gccttccagt cctcatctca gaaattgact agccagaagg
2401 aacagaaaaa cttagagtct tcaacaggct ttcagattcc atctcaggag ttagctagcc
2461 agatagatcc tcagaaagac atagagccta gaacaacgta tcagattgag aactttgcac
2521 aagcgtttgg ttctcagttt aagtcgggca gcagggtgcc aatgaccttt atcactaact
2581 ctaatggaga agtggaccat agagtaagga cttcagtgtc agatttctca gggtatacaa
2641 atatgatgtc tgatgtaagt gagccatgta gtacaagagt aaagacaccc accagccaga
2701 gttacaggta aggtcccaaa agtggccagg ctggaggtct tctaatgtaa ttttgtttta
2761 ttttgagaac actgccattg gaatgtttct acacgatcct attaagaata atgtgatgcc
2821 ctttcaatgc aacttttcat atttagttta ttttgttagc gtgattttag ctctgtttgt
2881 attatgattt ttaatcaaaa tcaatagatt aaaaatagtt tgacattcaa agtgacaatg
2941 tttagcaatc aaatttacat gtatagatcg tcagggaata gcccaaatgt tttaaacgca
3001 aaaaaaagac aaaaaaaaac caaaaaaaa
//