LOCUS AF124733 2212 bp mRNA linear HUM 11-JAN-2000
DEFINITION Homo sapiens iroquois homeobox protein 4 (IRX4) mRNA, complete cds.
ACCESSION AF124733
VERSION AF124733.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2212)
AUTHORS Bruneau,B.G., Bao,Z.Z., Tanaka,M., Schott,J.J., Izumo,S.,
Cepko,C.L., Seidman,J.G. and Seidman,C.E.
TITLE Cardiac expression of the ventricle-specific homeobox gene Irx4 is
modulated by Nkx2-5 and dHand
JOURNAL Dev. Biol. 217 (2), 266-277 (2000)
PUBMED 10625552
REFERENCE 2 (bases 1 to 2212)
AUTHORS Bruneau,B.G., Bao,Z.-Z., Cepko,C.L., Seidman,J.G. and Seidman,C.E.
TITLE Direct Submission
JOURNAL Submitted (29-JAN-1999) Genetics, Harvard Medical School, 200
Longwood Ave, Boston, MA 02115, USA
FEATURES Location/Qualifiers
source 1..2212
/db_xref="H-InvDB:HIT000070482"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="5"
/map="5p15.3"
gene 1..2212
/gene="IRX4"
CDS 120..1679
/gene="IRX4"
/note="homeodomain-containing protein"
/codon_start=1
/product="iroquois homeobox protein 4"
/protein_id="AAF23887.1"
/translation="MSYPQFGYPYSSAPQFLMATNSLSTCCESGGRTLADSGPAASAQ
APVYCPVYESRLLATARHELNSAAALGVYGGPYGGSQGYGNYVTYGSEASAFYSLNSF
DSKDGSGSAHGGLAPAAAAYYPYEPALGQYPYDRYGTMDSGTRRKNATRETTSTLKAW
LQEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWPPRNKCADEK
RPYAEGEEEEGGEEEAREEPLKSSKNAEPVGKEEKELELSDLDDFDPLEAEPPACELK
PPFHSLDGGLERVPAAPDGPVKEASGALRMSLAAGGGAALDEDLERARSCLRSAAAGP
EPLPGAEGGPQVCEAKLGFVPAGASAGLEAKPRIWSLAHTATAAAAAATSLSQTEFPS
CMLKRQGPAAPAAVSSAPATSPSVALPHSGALDRHQDSPVTSLRNWVDGVFHDPILRH
STLNQAWATAKGALLDPGPLGRSLGAGANVLTAPLARAFPPAVPQDAPAAGAARELLA
LPKAGGKPFCA"
BASE COUNT 395 a 782 c 707 g 328 t
ORIGIN
1 tcctgcttcg ccctcccagc gcctagaagc ctgcagctcc ggagcagtgg ccgcgccacg
61 ccggccccag cgcgcagaac cctgcaggcc ccgcccgtcc gccccgggcc gcgcccgcca
121 tgtcctaccc gcagtttgga tacccctact cctcggctcc ccagttcttg atggccacca
181 actccctgag cacgtgctgc gagtccggcg gccgcacgct ggcggactcc gggcccgccg
241 cctcggccca ggcgccggtc tactgcccgg tctacgagag ccggctgctg gccaccgcgc
301 gccacgagct caactcggcc gcggcgctgg gcgtctatgg gggtccctat ggcggatcgc
361 agggctatgg caactacgtg acctacggct cggaggcgtc cgccttctac tcgctgaaca
421 gctttgattc caaggatggt tcgggatctg cgcatggggg cctggcacca gccgctgccg
481 cctactaccc ttacgagccg gctctgggcc agtaccccta tgacaggtat ggaaccatgg
541 acagcggcac gcggcgcaag aacgccacgc gcgagaccac cagcacgctc aaggcctggc
601 tgcaggagca ccgcaagaac ccctacccca ccaagggcga gaagatcatg ctggccatca
661 tcaccaagat gaccctcaca caggtctcca cctggttcgc caacgcgcgc cggcgcctca
721 agaaggagaa caagatgacg tggccgccgc ggaacaagtg cgcagacgag aagcggccct
781 acgcggaggg cgaggaggag gaggggggcg aggaggaggc gcgggaggag cccctcaaga
841 gctccaagaa cgcagagccc gtgggcaaag aggagaagga gctggagctt agtgacttgg
901 acgacttcga cccgctggaa gcagagccgc cggcgtgcga gctgaagccg cccttccact
961 ccctggacgg cggtctggag cgcgtccccg ccgcgcccga cggcccggtc aaggaggcct
1021 caggcgcgct ccggatgtct ctggccgcgg gtggcggagc tgctctggac gaggacctgg
1081 agagggcccg gagctgtctc cgcagcgcgg cggccgggcc ggagccactg ccgggcgcag
1141 agggcggccc tcaggtctgc gaggccaagc tggggtttgt gccggcgggg gcgtcggcag
1201 gcttggaggc taagccgcgc atctggtccc tggcccacac agccaccgcc gccgccgccg
1261 ccgccacctc cctgagccag actgagtttc cgtcgtgcat gctcaagcgc caaggtcccg
1321 cggcccctgc ggctgtgtcc tccgcgcccg ccacgtcccc gtctgtggcc cttccccact
1381 ctggcgccct ggacaggcac caggactccc cggtaaccag tctcagaaac tgggtggacg
1441 gggtcttcca cgaccccatc ctcaggcaca gcactttgaa ccaggcctgg gccaccgcca
1501 agggcgccct cctggacccc gggcctctgg gacgctcgct gggggcgggc gcgaacgtgc
1561 tgactgcacc cctggcccgc gcctttccgc ctgccgtgcc ccaggacgcc ccagctgcag
1621 gcgccgccag ggagctgctc gccctgccca aggccggcgg caaacccttc tgcgcctgag
1681 gcgggcgggt cccgagccca ggagggaacc cgcgctcagg cggacggcgc cgactctttt
1741 cactgagttt ccagaggaag actagcgcgg ccaccgcgaa gccgccaacc caccggagag
1801 ggggcttctg aacttggact cctgggaaca tggacaagcc cggcgctgcc acgccggggc
1861 ctccaccgcc tgggcctgag cctgaccggg ccattcccaa atttgggacg cggaaggaga
1921 ggctctcgga gcagaagagg ccagataccc tgaagcataa agtttaacgt caaaagttta
1981 acatggagaa ggcggttccg ttctgaagcg tggtctgctg tcccctgggc gtgaggcctc
2041 ctgggcctgt cgggcctccg atttcatcct cagacgtaat gctcaccaac agcacttgca
2101 ctgagttgac tcttgcacac tcgactccat aatatgatgc tttttaagat gtatgttcac
2161 accaataatt gcctgcttca gaggctaata taacaaaacc aataaaaccg ag
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