LOCUS AF123659 5492 bp mRNA linear HUM 07-APR-1999
DEFINITION Homo sapiens FEZ1 (FEZ1) mRNA, complete cds.
ACCESSION AF123659
VERSION AF123659.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5492)
AUTHORS Ishii,H., Baffa,R., Numata,S.I., Murakumo,Y., Rattan,S., Inoue,H.,
Mori,M., Fidanza,V., Alder,H. and Croce,C.M.
TITLE The FEZ1 gene at chromosome 8p22 encodes a leucine-zipper protein,
and its expression is altered in multiple human tumors
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 96 (7), 3928-3933 (1999)
PUBMED 10097140
REFERENCE 2 (bases 1 to 5492)
AUTHORS Ishii,H., Baffa,R., Numata,S.I., Murakumo,Y., Rattan,S., Inoue,H.,
Mori,M., Fidanza,V., Alder,H. and Croce,C.M.
TITLE Direct Submission
JOURNAL Submitted (27-JAN-1999) Immunology/Microbiology, Kimmel Cancer
Institute, 233S 10th street, Philadelphia, PA 19107, USA
FEATURES Location/Qualifiers
source 1..5492
/db_xref="H-InvDB:HIT000070400"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="8"
/map="8p22"
gene 1..5492
/gene="FEZ1"
CDS 112..1902
/gene="FEZ1"
/codon_start=1
/product="FEZ1"
/protein_id="AAD23840.1"
/translation="MGSVSSLISGHSFHSKHCRASQYKLRKSSHLKKLNRYSDGLLRF
GFSQDSGHGKSSSKMGKSEDFFYIKVSQKARGSHHPDYTALSSGDLGGQAGVDFDPST
PPKLMPFSNQLEMGSEKGAVRPTAFKPVLPRSGAILHSSPESASHQLHPAPPDKPKEQ
ELKPGLCSGALSDSGRNSMSSLPTHSTSSSYQLDPLVTPVGPTSRFGGSAHNITQGIV
LQDSNMMSLKALSFSDGGSKLGHSNKADKGPSCVRSPISTDECSIQELEQKLLEREGA
LQKLQRSFEEKELASSLAYEERPRRCRDELEGPEPKGGNKLKQASQKSQRAQQVLHLQ
VLQLQQEKRQLRQELESLMKEQDLLETKLRSYEREKTSFGPALEETQWEVCQKSGEIS
LLKQQLKESQTEVNAKASEILGLKAQLKDTRGKLEGLELRTQDLEGALRTKGLELEVC
ENELQRKKNEAELLREKVNLLEQELQELRAQAALARDMGPPTFPEDVPALQRELERLR
AELREERQGHDQMSSGFQHERLVWKEEKEKVIQYQKQLQQSYVAMYQRNQRLEKALQQ
LARGDSAGEPLEVDLEGADIPYEDIIATEI"
BASE COUNT 1137 a 1704 c 1565 g 1086 t
ORIGIN
1 tgagggcttt gctatgacct cagtcccctc acggagccac gactgcccct tgctgccaca
61 gcctttccaa gaccctgccc ggccctgccc catcctcagc cccgagtcac catgggcagc
121 gtcagtagcc tcatctccgg ccacagcttc cacagcaagc actgccgggc ttcgcagtac
181 aagctgcgca agtcctccca cctcaagaag ctcaaccggt attccgacgg gctgctgagg
241 tttggcttct cccaggactc cggtcacggc aagtccagct ccaaaatggg caagagcgaa
301 gacttcttct acatcaaggt cagccagaaa gcccggggct cccatcaccc agattacacg
361 gcactgtcca gcggggattt agggggccag gctggggtgg actttgaccc gtccacaccc
421 cccaagctca tgcccttctc caatcagcta gaaatgggct ccgagaaggg tgcagtgagg
481 cccacagcct tcaagcctgt gctgccacgg tcaggagcca tcctgcactc ctccccggag
541 agtgccagcc accagctgca ccccgcccct ccagacaagc ccaaggagca ggagctgaag
601 cctggcctgt gctctggggc gctgtcagac tccggccgga actccatgtc cagcctgccc
661 acacacagca ccagcagcag ctaccagctg gacccgctgg tcacacccgt gggacccaca
721 agccgttttg ggggctccgc ccacaacatc acccagggca tcgtcctcca ggacagcaac
781 atgatgagcc tgaaggctct gtccttctcc gacggaggta gcaagctggg ccactcgaac
841 aaggcagaca agggcccctc gtgtgtccgc tcccccatct ccacggacga gtgcagcatc
901 caggagctgg agcagaagct gttggagagg gagggcgccc tccagaagct gcagcgcagc
961 tttgaggaga aggagcttgc ctccagcctg gcctacgagg agcggccgcg gcgctgcagg
1021 gacgagctgg agggcccgga gcccaaaggc ggcaacaagc tcaagcaggc ctcgcagaag
1081 agccagcgcg cgcagcaggt cctgcacctg caggtactgc agcttcagca ggagaagcgg
1141 cagctccggc aggagctcga gagcctcatg aaggagcagg acctgctgga gaccaagctc
1201 aggtcctacg agagggagaa gaccagcttc ggccccgcgc tggaggagac ccagtgggag
1261 gtgtgccaga agtcaggcga gatctccctc ctgaagcagc agctgaagga gtcccagacg
1321 gaggtgaacg ccaaggctag cgagatcctg ggtctcaagg cacagctgaa ggacacgcgg
1381 ggcaagctgg agggcctgga gctgaggacc caggacctgg agggcgccct gcgcaccaag
1441 ggcctggagc tggaggtctg tgagaatgag ctgcagcgca agaagaacga ggcggagctg
1501 ctgcgggaga aggtgaacct gctggagcag gagctgcagg agctgcgggc ccaggccgcc
1561 ctggcccgcg acatggggcc gcccaccttc cccgaggacg tccctgccct gcagcgggag
1621 ctggagcggc tgcgggccga gctgcgggag gagcggcaag gccatgacca gatgtcctcg
1681 ggcttccagc atgagcggct cgtgtggaag gaggagaagg agaaggtgat tcagtaccag
1741 aaacagctgc agcagagcta cgtggccatg taccagcgga accagcgcct ggagaaggcc
1801 ctgcagcagc tggcacgtgg ggacagcgcc ggggagccct tggaggttga cctggaaggg
1861 gctgacatcc cctacgagga catcatagcc actgagatct gaggggctgc ctgggaaggc
1921 gagtctgggg acctggcact gggaggcagg gctctcccgt gcatcccccc tgctcagcaa
1981 ttcagacccc tctgagagac gccactccct gggacacaga cccaggaccc ccgaggggag
2041 ggcaggatgg cctttccttc cctctctgat gtcccagtgc tcaccagccc tgcagcccac
2101 cagacgtcag gccctgactc ctctggcttt cccaggagat gggtccaggg gtctgtctgc
2161 tttggttaag ggctccctaa actttggcct ttgttcgaaa tagatatcct ctccccctcc
2221 tccagggaag gtggccacag caagaacagc ggctcccctc cgcttctcat cccaacctct
2281 ttttcctcct ggacacattg gaatgccttg gaaatagaaa gaagccatat atgaccagaa
2341 gccttggaac cagccccatc agaacctgag ctattttcct ctggccgcag aggtgtaggg
2401 gtggaatgag ccgcggggaa gctggctttg aaacctcagg gctgtcccag ccccggcaag
2461 ccacaggaag gaggggagag acaggcagcc cagcagtgtg gagaccctgc cacagccaga
2521 ggagggcaga gggagaatcc aagggttgag agccagtggc gggtgatggc cagcccctgg
2581 ggcccagccc ctgtttactg gttcttgcaa atgggagctg agcagcctct ggacagccag
2641 tgacctttga cctcggtgac cactcttctt taagccatag accctgaggc cctgggctgg
2701 gtgctgggaa gggagggttg aaaccaccgt gaaccagagg gtgtggcttt ccaggcaccc
2761 tcagggagcc tccccatctg tccagctggg gccagaggct gggagtccct acctgcttca
2821 cgttggccgg cggctactct ggaatgtttt tccctcccca gaatcaagct tttgcttgat
2881 ccagaagagc ccatatcact aagatggcat atatgtgatc tgggcatttt cctcctctgc
2941 ctacagccag gtttagcggc aaacctttcc cccttagcac cttcagggct gagttctggg
3001 tttctagagg tcaggacggc tcctcagagc gccaggaagc cagagcccca agcaggacga
3061 aaaagaggca tacacacagc agtgtgaata gcctggccac cagccatcct ccctccacct
3121 caagaccccc atttgtccca gactaaagga tccagagagc agctcccttt ctcaggagct
3181 tgggcagtgc cccagggagt ccagggtttc tctgcagatg tgcggagcgg gaggcggtgg
3241 tagagagaga taaaaggtgg agtttctctg ttgtttggtt cagggatttt atttttaatt
3301 ttatgagaca gggtcttgct ctgtccccca ggctggagtg cagtggcatg atcatagctc
3361 actgcagcct catactcctg ggctcaagca atcctcctgc ctcagccttc caactagctg
3421 ggactacagg tgcgcgccac cgtgcctggc taacttttca ttttttttgt agggacgggg
3481 tctcgttttg ttgccaaagc tggtctcaaa cttgtggcct caagcaatcc acctgccttg
3541 gcctcccaaa gtgctgagat tgcagatgtg agccaccgtg cctggccaga tttttctttt
3601 attcttcttt ctttttcttt tttgctttct tgtcttttca gaagcaagcc agacctagca
3661 ggctgttcca tgttctattt ttgactgtag ccacagctgc tgttctcagg acagcatccc
3721 ttcccacatg cctgcgcctg ctgcctgctg agatgaggag gggagcgtct gggaacttgc
3781 gagtccaagg ccagtcccca tttctgcctc gctcaccgct ggcccttaga gaccccgagg
3841 taggggtggg gagatgcttc tctccttgcc ccccgccctc atgggtccta gcccttccct
3901 gagtgcgggc tgaggccaga gtcacctttt ctgtggctgg ctctaccttc ctgtccctga
3961 ggttaaacgg tgcccatcct gccatcctca aacgacagag gagcttttct ggaatttcaa
4021 accattgctc ttagtcccaa gctaggctta aacctggaat ctacaagcca aaagtccctc
4081 cctgcctgag ggcagtaccc tccattgggc acagtccaga cccaagtcaa agatgcccca
4141 ttccttgcgc ctcagccctc agttccttca tttccaccag gccgtgcctt gtttgagttt
4201 ttcctcccag tgagactgcc ccacggagac agaggaaagg gctggctccc cctccccagg
4261 ctggagaccc cccccaactc caggaaagag cagtcagagt ccagtgctct gcctcagacg
4321 ttgcctgaga agaagtggct gccacaccca ggggaaggcc ctgaggcgga ggctgtgctc
4381 cgccatggtg tcccggtacc ttccatacac agaggagtgc agccttctcc atatctccat
4441 ggccctgtcc caggccggcc cagatgtgtc ccccccaggc cttgtcctac gtccaaggtg
4501 gcagatgtct tccctgggct gccaccagcc cccgccccag agtggcccac cgtggcacta
4561 gaatgcaagt atcctgcgac cttgcaacct caccttcctg tgggtgttct ttcctgccct
4621 gtccaaaagc gccctcacta ttcttggacc atgccagatt ctgcctctct ggaaagaggc
4681 tctggacagc agaagcctcc aagcacagag cctggcccca ggccccagac agggtgggct
4741 tcctgccctt ccctctgggc acgcctgctg gccgacccac tgacccactc ggatggacca
4801 acctgctctg tccccaaagg acgcctgcag gagagagcag cactccgcat cacctcacca
4861 aggatcggac tctgcccctg gacctgggaa cgactggact gtcacggggt tccctcctag
4921 ctctcccagt gaactcctgc caggcacaca cagcccctat agcactgagc tcacatggga
4981 ctgggatatg ggggcatctc ttccccagag aggcactcag tgagcctcct gtgcctggcc
5041 ccagtctggg ccatctctta ggtgagacag ttgcccgaaa ctaagccagg cctggctgga
5101 ggagcagcag cttggggaga gggatttccc tgcagacctc aagccatcat gcggtgggtg
5161 ctgccatgac agaggctgca cccctgggcc agcggggctg ctcacccacc tcttgtgcaa
5221 ggtggccttt gtgctgcgcc tgcaggcaga gctggagccc ccagcagagg caggctggga
5281 cggaccagca tctggaagat gtacatagtt atttttctct ttgtggtttc ttgtttggtt
5341 tggtttgctt ttgacagctt cattttattt ttgacgtcac tttttggcca tgtaaactat
5401 ttgtggcaat tttatgtttt tatttatgaa taaagaatgc catttctcac gccctctaaa
5461 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aa
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