LOCUS AF119818 10141 bp mRNA linear HUM 26-JUL-2016
DEFINITION Homo sapiens discs, large (Drosophila) homolog-associated protein 2
(DLGAP2) mRNA, alternatively spliced, partial cds.
ACCESSION AF119818
VERSION AF119818.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 10141)
AUTHORS Ranta,S., Zhang,Y., Ross,B., Takkunen,E., Hirvasniemi,A., de la
Chapelle,A., Gilliam,T.C. and Lehesjoki,A.E.
TITLE Positional cloning and characterisation of the human DLGAP2 gene
and its exclusion in progressive epilepsy with mental retardation
JOURNAL Eur. J. Hum. Genet. 8 (5), 381-384 (2000)
PUBMED 10854099
REFERENCE 2 (bases 1 to 10141)
AUTHORS Ranta,S., Zhang,Y., Ross,B., Takkunen,E., Hirvasniemi,A., de la
Chapelle,A., Gilliam,T.C. and Lehesjoki,A.-E.
TITLE Direct Submission
JOURNAL Submitted (13-JAN-1999) Medical Genetics, University of Helsinki,
PO Box 21 (Haartmaninkatu 3), University of Helsinki 00014, Finland
FEATURES Location/Qualifiers
source 1..10141
/db_xref="H-InvDB:HIT000070222"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="8"
/map="8p23; between D8S264 and D8S504"
/tissue_type="brain"
gene <1..10141
/gene="DLGAP2"
CDS <1..3062
/gene="DLGAP2"
/note="alternatively spliced"
/codon_start=3
/product="discs, large (Drosophila) homolog-associated
protein 2"
/protein_id="AAF34345.1"
/translation="EEAGDLVQPGISFPGPAEEDLDPQYSWSPTQHFNEERYSPAPRS
MKGLSGSRTQPPLCSGHTCGLAPPEDCEHLHHGPDARPPYLLSPADSCPGGRHRCSPR
SSVHSECVMMPVVLGDHVSSSTFPRMHYSSHYDTRDDCAVAHAGAKINRIPANLLDQF
EKQLPLHRDGFHTLQYQRTSAAAEQRSESPGRIRHLVHSVQKLFTKSHSLEGSSKSNA
NGTKADGRADDHHHAHHAKHSKRSKSKERKPEGKPRPGMSSWWSSDDNLDSDSTYRTP
SVLNRHHLGPVAHCYPDALQSPFGDLSLKTSKSNNDVKCSACEGLALTPDAKYLKRSS
WSTLTVSQAKEAYRKSSLNLDKPLLHQDAKPALRPCHYLQVPQDEWGGYPTGGKDEEI
PCRRMRSGSYIKAMGDEESGESDSSPKTSPKSAILXEPLLKSIGQRPLGEHQTQTYLQ
AASDVPVGHSLDPAANYNSPKFRSRNQSYMRAVSTLSQASCVSQVSEAEINGQFESVC
ESVFSEVESQAMDALDLPGCFRTRSHSYLRAIQAGYSQDDECIPMMTPSDITSTIRST
AAVSYTNYKKTPPPVPPRTTSKPLISVTAQSSTESTQDAYQDSRAQRMSPWPQDSRGL
YNSTDSLDSNKAMNLALETAAAQRHLPESQSSSVRTSDKAILVSKAEELLKSRCSSIG
IQDSEFPEHQPYPRSDVETATDSDTESXGLREYHSVGVQVEDEKRHGRFKRSNSVTAA
VQADLELEGFPGHITTEDKGLQFGSSFQRHSEPSTPTQYSAVRTVRTQGLFSYREDYR
TQVDTSTLPPPDPWLEPAIDTVETGRMSPCRRDGSWFLKLLHAETKRMEGWCKEMERE
AEENDLSEEILGKIRSAVGSAQLLMSQKFQQFYWLCQQNMDPSAMPRPTSQDLAGYWD
MLQLSIEDVSMKFDELQRLRLNDWKMMESPERKEERKVPPPIPKKPPKGKFPITREKS
LDLPDRQRQEARRRLMAAKRAASFRQNSASERADSIEIYIPEAQTRL"
BASE COUNT 2677 a 2594 c 2371 g 2484 t
ORIGIN
1 aggaagaagc tggagacttg gtccagccgg gcatcagctt tccggggccg gcagaggagg
61 atctagaccc gcagtactca tggtcgccca cgcagcactt caatgaggag cgctactcgc
121 ccgcgcccag gagcatgaag ggcctttccg gaagtcggac ccagccgccg ctgtgttccg
181 ggcacacgtg tggtctggcg cccccggagg actgcgagca cctgcaccac gggcccgacg
241 cgcggccgcc ctacctgctg agccccgccg acagctgccc cggggggcgc caccgctgct
301 cgccgcgcag ctcggtgcac tcggagtgcg tgatgatgcc ggtggtgctg ggcgaccacg
361 tgtccagcag caccttcccg cggatgcact acagctcgca ctacgacacg cgcgacgact
421 gcgctgtggc ccacgcgggc gccaagatca accgcatccc ggccaacctg ctggaccagt
481 tcgagaagca gctgccgctg caccgggacg gcttccacac gctgcagtac cagaggacgt
541 ccgcggccgc cgagcagcgc agcgagagcc ccgggcggat ccgccacctg gtacactccg
601 tgcagaagct cttcaccaag tcgcactcgc tggagggctc ctccaaaagc aacgccaacg
661 gcaccaaggc ggacggccgg gcggacgacc accaccacgc ccaccacgcc aagcacagca
721 agaggagcaa gagcaaggag cgcaagccgg agggcaagcc ccggcccggc atgagcagct
781 ggtggagctc ggacgacaac ctggacagcg acagcaccta tcggacgccc agcgtgctca
841 accggcacca cctgggcccc gtggcccact gctaccccga cgcgctgcag agccccttcg
901 gggacctgtc cctcaagacc tccaagagca acaacgacgt caagtgctcg gcctgtgagg
961 ggttggcgct gacgcccgac gccaagtacc tgaagcgcag ctcctggtct acgctgacgg
1021 tcagccaggc caaggaggcc taccgcaaga gctcgctgaa cctggacaag ccgctgctgc
1081 accaggacgc caagcccgcc ctgaggccgt gccactacct ccaggtacct caggatgagt
1141 ggggagggta ccccaccggt ggcaaagatg aggagattcc ctgcaggaga atgagaagtg
1201 ggagttacat taaagccatg ggggacgagg agagcggaga gtcagactcc agccccaaga
1261 catcaccaaa gtcggcaatc ctacmagagc cgctgctgaa gtccatcgga cagagaccgc
1321 ttggagagca ccagacccag acctacctgc aagctgcaag cgatgtgcct gtgggacaca
1381 gcctggaccc cgctgcgaac tacaactccc cgaaattccg ctcccggaac cagagctaca
1441 tgagggccgt cagcaccctg agccaggcca gctgcgtgag ccaggtgagc gaggcggaga
1501 tcaatgggca attcgagtcc gtgtgcgagt ccgtcttcag tgaagttgaa tctcaggcca
1561 tggatgccct cgacctcccg ggatgtttcc gaacaaggag tcacagctac cttcgagcca
1621 ttcaagccgg ctactcccaa gatgacgaat gtattcccat gatgacaccc tctgacatca
1681 cctccaccat caggtcaaca gcagctgtct catatacaaa ttacaagaaa acgcccccac
1741 cggtgccccc tcggaccacc tccaagcctc tgatctcggt gacggcgcag agcagcaccg
1801 aatccaccca ggacgcctac caggacagcc gcgcacagag gatgtccccg tggccccagg
1861 acagccgcgg cctctacaac tccacggaca gcctggacag caacaaggcc atgaacctcg
1921 cgctggarac ggccgctgcc cagcgccacc tgccagagag ccagagcagc tctgtgcgga
1981 ccagcgacaa ggccatcctg gtgtccaagg cggaggagct cctcaagagc cgctgctcct
2041 ccatcgggat tcaggattct gaattcccag agcatcagcc atacccaagg tcagatgtgg
2101 aaacggccac agattctgac acggagagcy gcggtctgcg ggaataccac tctgtcgggg
2161 tgcaagtgga agatgagaag cgacacggac gttttaaacg ttctaacagc gtcacggccg
2221 ccgtccaagc tgacctggag ctggaggggt tcccaggcca catcaccacg gaggacaaag
2281 gccttcagtt cggctcatcc ttccagcggc actccgagcc cagcaccccc acccagtaca
2341 gcgcggtgag aactgtacgg acccaggggc tcttcagcta tagagaagac tatcggaccc
2401 aagtggacac ctccaccctg ccccctccag acccctggct ggagcccgcc atcgacacgg
2461 tagagactgg gaggatgtct ccgtgccgca gggatggctc gtggtttttg aagctgctgc
2521 acgcagagac aaagaggatg gaaggctggt gcaaagagat ggagagagag gcggaggaga
2581 acgacctctc ggaggaaatt ctcggtaaaa tcaggagtgc tgttgggagt gcccagcttc
2641 tcatgtccca gaaattccag cagttttatt ggctttgcca acagaatatg gaccccagcg
2701 ccatgccgag gccgacgtcg caggacctgg ccggctactg ggacatgctg cagctctcca
2761 ttgaggacgt cagcatgaag ttcgacgagc tgcagcggct gcggctcaac gactggaaga
2821 tgatggagtc cccggaaaga aaggaagaaa gaaaggtccc gcctccaata ccaaagaagc
2881 ctcccaaggg gaagtttccc atcacaagag aaaaatccct ggacctgccc gacagacaac
2941 gccaggaagc ccggaggcgc ctcatggccg ccaagcgagc ggcgtccttc cggcagaatt
3001 ccgcctccga gcgcgcggac agcatcgaga tctacatccc cgaggcccag acccggctct
3061 gagggcggag gccggcgcct tcccctcgtc gcttccgctt tcccggacgc ttgtgcagcg
3121 cggcgccgcc ctggtggttt ctgtctcctc ctcccgctga acacgtcctc gctcccgcgc
3181 tccccgcgcc ccggacacag cgggacgcgg ccggcggcct cagagtccac ggagctcgcg
3241 gcgaggacga cttctgcttt tgttgttgtt gttgttgttc acgggtggcc tggctcacac
3301 ttggctctga gggacaggtg tggcgagacc tgatttctcc tgcgtgttct cagaggacgg
3361 cgagaaatgc ctctggagct ggaacccagc ttacattttg ttatttctat ttttataaat
3421 tgtgtgawaa ttagaggtaa gaataacaar taactataaa cgggtgcatc ccaccactcc
3481 ctggaggcat tagacaccca agtggaaggt gctacaacct gaagcgcagg aaagaaaggc
3541 ccattcccct cgcacagccg agcttttact ccctgagcac gggccgctcc gctcccctgc
3601 tcctgtctgt ctcggacaga aaacacgagg ctccttgtgt caagcttcct gtgatggaaa
3661 gcgacctctc caaccaccac actccccgcc gtacagttct ccagaatccc aggcgatgac
3721 aagtctgaac ccacgaaaat acccagcgca gcatctacac attcaaaaga taagctgagt
3781 gttcccacca ggaagtcacg cgcagagagg agagtcttac ggagggctgg gagcttaaaa
3841 ggaaaacaat gtccttactt gtaaacagtt attgtatttt ttatttcttt ctaacttaaa
3901 atacgacacc cagtattttc tttaagtttc accatttacg ctacatgtga tttttttaat
3961 gtatgtatat atatatattc tcaaattgct ctatcagctg acttttcagg gtatccttaa
4021 aaaaaaacac acacgaaaaa caaaagtttg cttgtttaaa atgacagttg tgatgtaaaa
4081 agtttaagaa atatgaatgt gagtggtaag tatatctcag tttaaatggt aaagaagaaa
4141 tgtagtttac atttgtattt ttccagaatt cttttgtcct atgcagtatt gctaaagtcg
4201 agaatatatt ccttgcctgt gttagacatg aagggaaaaa gaggtcacat attgtgattt
4261 ccagctgtag cattcaaaaa aaaaattggt gttcatgact ctgtggtcgg tgccagagga
4321 aaataggaac gactctaatt aataggcttt ctgtgtatat aattaaattt agctgctgca
4381 accattgttc tgacacgact tctgtttcac agttcagacc ggtcttcaaa ggaaaagcct
4441 gtccgatttt tccatgggtt ccagtttcag agttctcatt attactcaaa gtaaaagcgg
4501 actgcgattt aagatgtttc caccccaata cctggtcttc cttcccggct taaggagtac
4561 catgtactta gccacaggca gaatagcttt cgatgacccc atagcacttt gtttcttcrc
4621 cttgatttgc actttacaat gtccccagcc cctctgcagc ccgtggctgg cagggcgttc
4681 gatgtgcggt tggcccccag cgcgccctcc agagmtgcgg tgtctccctg cctcattccc
4741 cacatcccac tgagcatggg accattggga gcagagctga tattaaagca tgtttagctt
4801 cgaagtttta cttttttaaa gctgagtagt taagaattcc ctgtaaaaac aaaaccctgt
4861 aaattgagcc tcatgtctgg tatatatttt accaaacagc cttaaaatat atttggaagc
4921 aaaaatcagt acgaatgtat ctccttgaaa aatgcaaaaa aaaaaaaaat cctggaatat
4981 cttctataat gaatcctaat tccccccaga gtgttcaagg catttttttt aactaatgaa
5041 tacctaaatc ttgagtagtg tacggtaatg acgcttcttc cctatatcca ctcttattat
5101 gttaaaacaa atgtatttgc gagtattggc attttaggac tttaaaaatg ctgtatgatt
5161 tccaggtgaa ctctgctgtt tagaagtaac cacagaaaag caaagtcagt gtacactctg
5221 agtgaaagga aatgtaatgt ggataaaggc ccgccacctc ctcacattgg tctatctact
5281 ggcagctgat acgtttaact catttccttg agcttataca aaacatagaa aagcaaactg
5341 ttaaagtagt caataattat ttgtctcaga tcccagattc tatgatccct gcttaaaaga
5401 aaatgttcac tgcatgtagg ttgatttctt atgttttgta gactcattgt tatttttcaa
5461 tccccaaaag tcttggccta aaccatccct aggggagcag attaacctac caatacattg
5521 cacagggttg gtgactcgac gtggtgaatg tgcacacgcc ctgcctggtc cgccatgttc
5581 caaagaagat gatttaatgg tagaacggat acctgctgct agacctgatg gaatgttacc
5641 tgtccgtgtt acataatcaa gtgcaatata ctcagttctc atgcaggtga cattctacca
5701 tgaaacgcag aagataagcc atgtttctgt attgtacatg taaagaaaaa taaaactgtt
5761 tatgatactt gtgttagtca ctcgagctag cttatttcag ccacttctag cagatcatgc
5821 catggagctc acgacgtgtg accatttcgt catatttaaa atataacttc aagaaaagag
5881 taaacatcca ttggagaaca cggctgaaaa ttattgtgct gttctaggaa catcatccta
5941 gagagtgtga tgttcactat aaccccatac ctacattccc taatgataca gccaatgaca
6001 ggtgaaaccc agacactctc cttagagccg acaggttgat cctgctgtgt tgaaggctgt
6061 ggttaataaa acacaagtat gataaacagg acctagcgtt tagcccggga aaggagaatg
6121 ctgcttgtca cctagagtgc tttccttgtg atgcgtctct cgcatcttca cgtgttgttg
6181 tgtttgaagt aaaactagtt gttatcgatg acaattttta ccatagtttt ctcagcaaat
6241 ttatatcacc atcttagaat ggtatataaa aaaattgaac tgtttatgat accaaaaaaa
6301 ttacagtttt gtttaaaagg aaatgttgat gttttcaact ccaaatcaat tctaaaaact
6361 tcaagcactt aatggaaagg taaatggtca gataaaaata taattacctg taaggttatc
6421 tggttttaaa agaaaaaaaa aaagcctaca aactcagtga cctactacgc agagggaatt
6481 tttccctgct gcttcttatg aaagtggcca ggtttattat tagaagacac agtggcagag
6541 cacacatgtg cacaggttct gattatttct cttggagcat atgtccttgt cttgattttt
6601 gccttttcga tgccatatta agcagccacc gtttccaccc ctttcattag aaggccctgc
6661 atccgtaaat tcgcgcatct ctgtttttgt tagatccttg taagcatcgc tacccgagtc
6721 caggatggaa tttcacagga aagtgaaggg atactgcagg cctgtgtttg cagcgcctgt
6781 ggtaactgtg gaatgagctc tgttagggac agttgtctgg tttgtgccaa accttcgagg
6841 ggcgagtagg gagtggggga ggtgggtcca agtctcccct caggaaggcc ttttctatcg
6901 gcagcaattc catcaagcca agcctcctgt ggtcctgagc atgaaggggc caggggacct
6961 cctgggagat gcagcttttg tttccgctgc gtttcatcag tcagccttgc ttggaattct
7021 ggcaggttcc ccggggtgtt tcagtggaca ggaggccccc gtgccgtggc tgagtcagcc
7081 tgggtacccc agtcaccagc agggccaccc ttgatgacag ggccccccac gaacctggga
7141 aaggcagcgg gaaatgtgtg agagggtgtg cgctggtacg gacataaaag cattgtccaa
7201 aacagcgctg gttcggggag ggcccctgga tactgccttt ggcccacact gaaaactgaa
7261 attgccccac ctgtgagcac agaaacacgc ttctccaaca cgggccgaaa taactaaact
7321 ccacatggtt cctgcctgct catttcccag ccctcttctt ctcaagcctg aacttcattt
7381 ttttttttag ctgcaaattt aacaggctaa tttaaaactg cagttttcag acgacagccc
7441 ctgggaatgt tccagggttc tcttgttttg atctgcatgt ctgtttacac ttctctgtag
7501 gcgtgggttg aatacaagtt tccaaaactt taaaatagaa aaccacgagc ttaagaggtg
7561 aaaaagatga cccctttctg attaggatct gtaactctgt gggctgggtc aatgcagtgt
7621 gcttcattca gggccatgtg gcagccatga cacacaccac ataaggtcag ctcagagccc
7681 atggcttccc tgcaggagcc ccatcttgtc gctattagtt gggagttgca atacattgtt
7741 ggccataaac aaagtgctaa aggaaagggt ttgcttctac acattcggct gaatgtcccc
7801 cagtgcaggg tggcagcaga atgttctgga aatgaaggag atattgctag gaatctctag
7861 gctgttaggc aacctggctt ttattcatcc tcagccggca actcatctca agtttatgtc
7921 tcagtttttt tcctctagaa aggggattac agttcctgtc cctgtcttcc tccaggacac
7981 actgtgagga ttaatgacat attggctcta aagtcctttg agctcctggg aacaggtggt
8041 gaaagtgtgc gttactgcta aggattagtc ctggctcttc tagaatgccg ccctcccagc
8101 tctgcagggc acgctgccag aatccaggct ggtcgtaaac atctcagaga taatcaggga
8161 ccaccagagg cagaggccat gagactgtct ttggaaaggt ttggaaatgc agaaataact
8221 acaagggcca ttctccttag cttctggctt tcaactgttt ctagatgctt ccaagaacaa
8281 gaacccagca ccaaccagaa ttaggccacr ttttcaccat tacttaagct caatcgcctc
8341 ttagatgaaa tgaggagata aactaaacat taaaatgatg aaggaaaaaa aattatttgg
8401 aagcmgaaaa ccrcatgggt ggggaaacat caggaacgaa atcagacaca ctgactcaaa
8461 ccacgcaagg gtttgagaag cccacccctc taattccagg ygtttgtaat ttctsyactt
8521 cgcacttgag agaaggcaga ggtggtccgt gggaaagctc cgggaaacag ccgtctttca
8581 tccttgccac attgaaaaat gtccacaatt ttatgaattg ctgtcctaac cctggcgttt
8641 ttatccagtg ttaaaataaa ttatttcaag tttcaatgta aacacttaac agatgacttc
8701 tttgcagaag aaatgttcgt tacctactat caaactactt tttaacagat tttgtatata
8761 cacacacaag ttgacagagg tttacctccc tactttctta gattttatgt aactcttttc
8821 attggtgctt attcagaacc tgaaagcctt gggcatccaa gctttcacct actcaatgga
8881 ggagaggtga taatgaatga aaagattgac accaggtttc ttggacaaat ttaagttcaa
8941 atttatctct ttcaagtaga ccatggtctc cctagagagt gtgttggctt gtgtctgcca
9001 gtacgacaaa ggacgctccc agcttgatcg tggtacctta tggaagccac tcacgcattc
9061 tctgatttac ccccaaaaca ctaccatgcc ccagccccac tcatttaaat aatacaatca
9121 tatcactttc aaagggctca gcacgaatgt tcccctcact ccacttttta actcgtttgc
9181 tgaactcgac aaggcttccc cttacgagca gtgagaccta ggctactttc gaacgcttcc
9241 ttccgaacgg taagccactt cgctctcggg caggacaggt cctccctgca gagagagaca
9301 actcatcccc cgaccttcca tactacagac caaaataccc aggtgtggcc taaggactat
9361 attaaatgcc tcctatagaa attcaaggaa tgttagaacc aggaaactag ctgtttaaag
9421 ttttaaagaa gtatataaat atatatataa atataaatat gaaatcatat cgagtgtgag
9481 gatgagcaga gtgccaaata ttcagcatct gtacaaagtc attcactgga attcaactat
9541 tttatgtcat tctctttctc acgcttttat ggttcttttg ataaattcta tttagtagca
9601 tgcaggatac ctaatctgaa tgtgcaatat gctattcatc accacgacaa tttcttactt
9661 cctcttaata acttaccaga atgttggtca ttcctttaag gcagttaagg attgctttan
9721 ttgtgttctt ttttcccatg actttttttc actctcagct gactgtaaga aactgtgcac
9781 cgtttccgcc ataaccgtcc tgtgacgatg cctccatttg acttctgtat cgctgatgtt
9841 cacctcctgt aaatagtttg gcaattaaat tttttgagaa aagtaatgtt tactttttta
9901 ttggagtgaa ttctcgtgtt attttaatct cagaaaaatt atatagacca aagagtttta
9961 tccgaaaaaa aattacactc ttcctccatt atatatttca ttgttgaaat atcctcaatt
10021 tctctatatt ttaagaagta atggacattt attaaggtta cagatttaat atgtatgcaa
10081 aatggtatag attaaatgag tttttaatta ataaatccta cagtatttag ttmaaaaaaa
10141 a
//