LOCUS AF119817 10126 bp mRNA linear HUM 31-JUL-2002
DEFINITION Homo sapiens discs, large (Drosophila) homolog-associated protein 2
(DLGAP2) mRNA, alternatively spliced, complete cds.
ACCESSION AF119817
VERSION AF119817.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 10126)
AUTHORS Ranta,S., Zhang,Y., Ross,B., Takkunen,E., Hirvasniemi,A., de la
Chapelle,A., Gilliam,T.C. and Lehesjoki,A.E.
TITLE Positional cloning and characterisation of the human DLGAP2 gene
and its exclusion in progressive epilepsy with mental retardation
JOURNAL Eur. J. Hum. Genet. 8 (5), 381-384 (2000)
PUBMED 10854099
REFERENCE 2 (bases 1 to 10126)
AUTHORS Ranta,S., Zhang,Y., Ross,B., Takkunen,E., Hirvasniemi,A., de la
Chapelle,A., Gilliam,T.C. and Lehesjoki,A.-E.
TITLE Direct Submission
JOURNAL Submitted (13-JAN-1999) Medical Genetics, University of Helsinki,
PO Box 21 (Haartmaninkatu 3), University of Helsinki 00014, Finland
FEATURES Location/Qualifiers
source 1..10126
/db_xref="H-InvDB:HIT000070221"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="8"
/map="8p23; between D8S264 and D8S504"
/tissue_type="testis"
gene 1..10126
/gene="DLGAP2"
CDS 120..3047
/gene="DLGAP2"
/note="alternatively spliced"
/codon_start=1
/product="discs, large (Drosophila) homolog-associated
protein 2"
/protein_id="AAF34344.1"
/translation="MKGLSGSRTQPPLCSGHTCGLAPPEDCEHLHHGPDARPPYLLSP
ADSCPGGRHRCSPRSSVHSECVMMPVVLGDHVSSSTFPRMHYSSHYDTRDDCAVAHAG
AKINRIPANLLDQFEKQLPLHRDGFHTLQYQRTSAAAEQRSESPGRIRHLVHSVQKLF
TKSHSLEGSSKSNANGTKADGRADDHHHAHHAKHSKRSKSKERKPEGKPRPGMSSWWS
SDDNLDSDSTYRTPSVLNRHHLGPVAHCYPDALQSPFGDLSLKTSKSNNDVKCSACEG
LALTPDAKYLKRSSWSTLTVSQAKEAYRKSSLNLDKPLLHQDAKPALRPCHYLQVPQD
EWGGYPTGGKDEEIPCRRMRSGSYIKAMGDEESGESDSSPKTSPKSAILXEPLLKSIG
QRPLGEHQTQTYLQAASDVPVGHSLDPAANYNSPKFRSRNQSYMRAVSTLSQASCVSQ
VSEAEINGQFESVCESVFSEVESQAMDALDLPGCFRTRSHSYLRAIQAGYSQDDECIP
MMTPSDITSTIRSTAAVSYTNYKKTPPPVPPRTTSKPLISVTAQSSTESTQDAYQDSR
AQRMSPWPQDSRGLYNSTDSLDSNKAMNLALETAAAQRHLPESQSSSVRTSDKAILVS
KAEELLKSRCSSIGIQDSEFPEHQPYPRSDVETATDSDTESXGLREYHSVGVQVEDEK
RHGRFKRSNSVTAAVQADLELEGFPGHITTEDKGLQFGSSFQRHSEPSTPTQYSAVRT
VRTQGLFSYREDYRTQVDTSTLPPPDPWLEPAIDTVETGRMSPCRRDGSWFLKLLHAE
TKRMEGWCKEMEREAEENDLSEEILGKIRSAVGSAQLLMSQKFQQFYWLCQQNMDPSA
MPRPTSQDLAGYWDMLQLSIEDVSMKFDELQRLRLNDWKMMESPERKEERKVPPPIPK
KPPKGKFPITREKSLDLPDRQRQEARRRLMAAKRAASFRQNSASERADSIEIYIPEAQ
TRL"
BASE COUNT 2677 a 2592 c 2363 g 2488 t
ORIGIN
1 ttcagcggcc tgaattctag aactttccgg ggccggcaga ggaggatcta gacccgcagt
61 actcatggtc gcccacgcag cacttcaatg aggagcgcta ctcgcccgcg cccaggagca
121 tgaagggcct ttccggaagt cggacccagc cgccgctgtg ttccgggcac acgtgtggtc
181 tggcgccccc ggaggactgc gagcacctgc accacgggcc cgacgcgcgg ccgccctacc
241 tgctgagccc cgccgacagc tgccccgggg ggcgccaccg ctgctcgccg cgcagctcgg
301 tgcactcgga gtgcgtgatg atgccggtgg tgctgggcga ccacgtgtcc agcagcacct
361 tcccgcggat gcactacagc tcgcactacg acacgcgcga cgactgcgct gtggcccacg
421 cgggcgccaa gatcaaccgc atcccggcca acctgctgga ccagttcgag aagcagctgc
481 cgctgcaccg ggacggcttc cacacgctgc agtaccagag gacgtccgcg gccgccgagc
541 agcgcagcga gagccccggg cggatccgcc acctggtaca ctccgtgcag aagctcttca
601 ccaagtcgca ctcgctggag ggctcctcca aaagcaacgc caacggcacc aaggcggacg
661 gccgggcgga cgaccaccac cacgcccacc acgccaagca cagcaagagg agcaagagca
721 aggagcgcaa gccggagggc aagccccggc ccggcatgag cagctggtgg agctcggacg
781 acaacctgga cagcgacagc acctatcgga cgcccagcgt gctcaaccgg caccacctgg
841 gccccgtggc ccactgctac cccgacgcgc tgcagagccc cttcggggac ctgtccctca
901 agacctccaa gagcaacaac gacgtcaagt gctcggcctg tgaggggttg gcgctgacgc
961 ccgacgccaa gtacctgaag cgcagctcct ggtctacgct gacggtcagc caggccaagg
1021 aggcctaccg caagagctcg ctgaacctgg acaagccgct gctgcaccag gacgccaagc
1081 ccgccctgag gccgtgccac tacctccagg tacctcagga tgagtgggga gggtacccca
1141 ccggtggcaa agatgaggag attccctgca ggagaatgag aagtgggagt tacattaaag
1201 ccatggggga cgaggagagc ggagagtcag actccagccc caagacatca ccaaagtcgg
1261 caatcctacm agagccgctg ctgaagtcca tcggacagag accgcttgga gagcaccaga
1321 cccagaccta cctgcaagct gcaagcgatg tgcctgtggg acacagcctg gaccccgctg
1381 cgaactacaa ctccccgaaa ttccgctccc ggaaccagag ctacatgagg gccgtcagca
1441 ccctgagcca ggccagctgc gtgagccagg tgagcgaggc ggagatcaat gggcaattcg
1501 agtccgtgtg cgagtccgtc ttcagtgaag ttgaatctca ggccatggat gccctcgacc
1561 tcccgggatg tttccgaaca aggagtcaca gctaccttcg agccattcaa gccggctact
1621 cccaagatga cgaatgtatt cccatgatga caccctctga catcacctcc accatcaggt
1681 caacagcagc tgtctcatat acaaattaca agaaaacgcc cccaccggtg ccccctcgga
1741 ccacctccaa gcctctgatc tcggtgacgg cgcagagcag caccgaatcc acccaggacg
1801 cctaccagga cagccgcgca cagaggatgt ccccgtggcc ccaggacagc cgcggcctct
1861 acaactccac ggacagcctg gacagcaaca aggccatgaa cctcgcgctg garacggccg
1921 ctgcccagcg ccacctgcca gagagccaga gcagctctgt gcggaccagc gacaaggcca
1981 tcctggtgtc caaggcggag gagctcctca agagccgctg ctcctccatc gggattcagg
2041 attctgaatt cccagagcat cagccatacc caaggtcaga tgtggaaacg gccacagatt
2101 ctgacacgga gagcygcggt ctgcgggaat accactctgt cggggtgcaa gtggaagatg
2161 agaagcgaca cggacgtttt aaacgttcta acagcgtcac ggccgccgtc caagctgacc
2221 tggagctgga ggggttccca ggccacatca ccacggagga caaaggcctt cagttcggct
2281 catccttcca gcggcactcc gagcccagca cccccaccca gtacagcgcg gtgagaactg
2341 tacggaccca ggggctcttc agctatagag aagactatcg gacccaagtg gacacctcca
2401 ccctgccccc tccagacccc tggctggagc ccgccatcga cacggtagag actgggagga
2461 tgtctccgtg ccgcagggat ggctcgtggt ttttgaagct gctgcacgca gagacaaaga
2521 ggatggaagg ctggtgcaaa gagatggaga gagaggcgga ggagaacgac ctctcggagg
2581 aaattctcgg taaaatcagg agtgctgttg ggagtgccca gcttctcatg tcccagaaat
2641 tccagcagtt ttattggctt tgccaacaga atatggaccc cagcgccatg ccgaggccga
2701 cgtcgcagga cctggccggc tactgggaca tgctgcagct ctccattgag gacgtcagca
2761 tgaagttcga cgagctgcag cggctgcggc tcaacgactg gaagatgatg gagtccccgg
2821 aaagaaagga agaaagaaag gtcccgcctc caataccaaa gaagcctccc aaggggaagt
2881 ttcccatcac aagagaaaaa tccctggacc tgcccgacag acaacgccag gaagcccgga
2941 ggcgcctcat ggccgccaag cgagcggcgt ccttccggca gaattccgcc tccgagcgcg
3001 cggacagcat cgagatctac atccccgagg cccagacccg gctctgaggg cggaggccgg
3061 cgccttcccc tcgtcgcttc cgctttcccg gacgcttgtg cagcgcggcg ccgccctggt
3121 ggtttctgtc tcctcctccc gctgaacacg tcctcgctcc cgcgctcccc gcgccccgga
3181 cacagcggga cgcggccggc ggcctcagag tccacggagc tcgcggcgag gacgacttct
3241 gcttttgttg ttgttgttgt tgttcacggg tggcctggct cacacttggc tctgagggac
3301 aggtgtggcg agacctgatt tctcctgcgt gttctcagag gacggcgaga aatgcctctg
3361 gagctggaac ccagcttaca ttttgttatt tctattttta taaattgtgt gataattaga
3421 ggtaagaata acaartaact ataaacgggt gcatcccacc actccctgga ggcattagac
3481 acccaagtgg aaggtgctac aacctgaagc gcaggaaaga aaggcccatt cccctcgcac
3541 agccgagctt ttactccctg agcacgggcc gctccgctcc cctgctcctg tctgtctcgg
3601 acagaaaaca cgaggctcct tgtgtcaagc ttcctgtgat ggaaagcgac ctctccaacc
3661 accacactcc ccgccgtaca gttctccaga atcccaggcg atgacaagtc tgaacccacg
3721 aaaataccca gcgcagcatc tacacattca aaagataagc tgagtgttcc caccaggaag
3781 tcacgcgcag agaggagagt cttacggagg gctgggagct taaaaggaaa acaatgtcct
3841 tacttgtaaa cagttattgt attttttatt tctttctaac ttaaaatacg acacccagta
3901 ttttctttaa gtttcaccat ttacgctaca tgtgattttt ttaatgtatg tatatatata
3961 tattctcaaa ttgctctatc agctgacttt tcagggtatc cttaaaaaaa aacacacacg
4021 aaaaacaaaa gtttgcttgt ttaaaatgac agttgtgatg taaaaagttt aagaaatatg
4081 aatgtgagtg gtaagtatat ctcagtttaa atggtaaaga agaaatgtag tttacatttg
4141 tatttttcca gaattctttt gtcctatgca gtattgctaa agtcgagaat atattccttg
4201 cctgtgttag acatgaaggg aaaaagaggt cacatattgt gatttccagc tgtagcattc
4261 aaaaaaaaaa ttggtgttca tgactctgtg gtcggtgcca gaggaaaata ggaacgactc
4321 taattaatag gctttctgtg tatataatta aatttagctg ctgcaaccat tgttctgaca
4381 cgacttctgt ttcacagttc agaccggtct tcaaaggaaa agcctgtccg atttttccat
4441 gggttccagt ttcagagttc tcattattac tcaaagtaaa agcggactgc gatttaagat
4501 gtttccaccc caatacctgg tcttccttcc cggcttaagg agtaccatgt acttagccac
4561 aggcagaata gctttcgatg accccatagc actttgtttc ttcaccttga tttgcacttt
4621 acaatgtccc cagcccctct gcagcccgtg gctggcaggg cgttcgatgt gcggttggcc
4681 cccagcgcgc cctccagagm tgcggtgtct ccctgcctca ttccccacat cccactgagc
4741 atgggaccat tgggagcaga gctgatatta aagcatgttt agcttcgaag ttttactttt
4801 ttaaagctga gtagttaaga attccctgta aaaacaaaac cctgtaaatt gagcctcatg
4861 tctggtatat attttaccaa acagccttaa aatatatttg gaagcaaaaa tcagtacgaa
4921 tgtatctcct tgaaaaatgc aaaaaaaaaa aaaatcctgg aatatcttct ataatgaatc
4981 ctaattcccc ccagagtgtt caaggcattt tttttaacta atgaatacct aaatcttgag
5041 tagtgtacgg taatgacgct tcttccctat atccactctt attatgttaa aacaaatgta
5101 tttgcgagta ttggcatttt aggactttaa aaatgctgta tgatttccag gtgaactctg
5161 ctgtttagaa gtaaccacag aaaagcaaag tcagtgtaca ctctgagtga aaggaaatgt
5221 aatgtggata aaggcccgcc acctcctcac attggtctat ctactggcag ctgatacgtt
5281 taactcattt ccttgagctt atacaaaaca tagaaaagca aactgttaaa gtagtcaata
5341 attatttgtc tcagatccca gattctatga tccctgctta aaagaaaatg ttcactgcat
5401 gtaggttgat ttcttatgtt ttgtagactc attgttattt ttcaatcccc aaaagtcttg
5461 gcctaaacca tccctagggg agcagattaa cctaccaata cattgcacag ggttggtgac
5521 tcgacgtggt gaatgtgcac acgccctgcc tggtccgcca tgttccaaag aagatgattt
5581 aatggtagaa cggatacctg ctgctagacc tgatggaatg ttacctgtcc gtgttacata
5641 atcaagtgca atatactcag ttctcatgca ggtgacattc taccatgaaa cgcagaagat
5701 aagccatgtt tctgtattgt acatgtaaag aaaaataaaa ctgtttatga tacttgtgtt
5761 agtcactcga gctagcttat ttcagccact tctagcagat catgccatgg agctcacgac
5821 gtgtgaccat ttcgtcatat ttaaaatata acttcaagaa aagagtaaac atccattgga
5881 gaacacggct gaaaattatt gtgctgttct aggaacatca tcctagagag tgtgatgttc
5941 actataaccc catacctaca ttccctaatg atacagccaa tgacaggtga aacccagaca
6001 ctctccttag agccgacagg ttgatcctgc tgtgttgaag gctgtggtta ataaaacaca
6061 agtatgataa acaggaccta gcgtttagcc cgggaaagga gaatgctgct tgtcacctag
6121 agtgctttcc ttgtgatgcg tctctcgcat cttcacgtgt tgttgtgttt gaagtaaaac
6181 tagttgttat cgatgacaat ttttaccata gttttctcag caaatttata tcaccatctt
6241 agaatggtat ataaaaaaat tgaactgttt atgataccaa aaaaattaca gttttgttta
6301 aaaggaaatg ttgatgtttt caactccaaa tcaattctaa aaacttcaag cacttaatgg
6361 aaaggtaaat ggtcagataa aaatataatt acctgtaagg ttatctggtt ttaaaagaaa
6421 aaaaaaaagc ctacaaactc agtgacctac tacgcagagg gaatttttcc ctgctgcttc
6481 ttatgaaagt ggccaggttt attattagaa gacacagtgg cagagcacac atgtgcacag
6541 gttctgatta tttctcttgg agcatatgtc cttgtcttga tttttgcctt ttcgatgcca
6601 tattaagcag ccaccgtttc cacccctttc attagaaggc cctgcatccg taaattcgcg
6661 catctctgtt tttgttagat ccttgtaagc atcgctaccc gagtccagga tggaatttca
6721 caggaaagtg aagggatact gcaggcctgt gtttgcagcg cctgtggtaa ctgtggaatg
6781 agctctgtta gggacagttg tctggtttgt gccaaacctt cgaggggcga gtagggagtg
6841 ggggaggtgg gtccaagtct cccctcagga aggccttttc tatcggcagc aattccatca
6901 agccaagcct cctgtggtcc tgagcatgaa ggggccaggg gacctcctgg gagatgcagc
6961 ttttgtttcc gctgcgtttc atcagtcagc cttgcttgga attctggcag gttccccggg
7021 gtgtttcagt ggacaggagg cccccgtgcc gtggctgagt cagcctgggt accccagtca
7081 ccagcagggc cacccttgat gacagggccc cccacgaacc tgggaaaggc agcgggaaat
7141 gtgtgagagg gtgtgcgctg gtacggacat aaaagcattg tccaaaacag cgctggttcg
7201 gggagggccc ctggatactg cctttggccc acactgaaaa ctgaaattgc cccacctgtg
7261 agcacagaaa cacgcttctc caacacgggc cgaaataact aaactccaca tggttcctgc
7321 ctgctcattt cccagccctc ttcttctcaa gcctgaactt catttttttt tttagctgca
7381 aatttaacag gctaatttaa aactgcagtt ttcagacgac agcccctggg aatgttccag
7441 ggttctcttg ttttgatctg catgtctgtt tacacttctc tgtaggcgtg ggttgaatac
7501 aagtttccaa aactttaaaa tagaaaacca cgagcttaag aggtgaaaaa gatgacccct
7561 ttctgattag gatctgtaac tctgtgggct gggtcaatgc agtgtgcttc attcagggcc
7621 atgtggcagc catgacacac accacataag gtcagctcag agcccatggc ttccctgcag
7681 gagccccatc ttgtcgctat tagttgggag ttgcaataca ttgttggcca taaacaaagt
7741 gctaaaggaa agggtttgct tctacacatt cggctgaatg tcccccagtg cagggtggca
7801 gcagaatgtt ctggaaatga aggagatatt gctaggaatc tctaggctgt taggcaacct
7861 ggcttttatt catcctcagc cggcaactca tctcaagttt atgtctcagt ttttttcctc
7921 tagaaagggg attacagttc ctgtccctgt cttcctccag gacacactgt gaggattaat
7981 gacatattgg ctctaaagtc ctttgagctc ctgggaacag gtggtgaaag tgtgcgttac
8041 tgctaaggat tagtcctggc tcttctagaa tgccgccctc ccagctctgc agggcacgct
8101 gccagaatcc aggctggtcg taaacatctc agagataatc agggaccacc agaggcagag
8161 gccatgagac tgtctttgga aaggtttgga aatgcagaaa taactacaag ggccattctc
8221 cttagcttct ggctttcaac tgtttctaga tgcttccaag aacaagaacc cagcaccaac
8281 cagaattagg ccacattttc accattactt aagctcaatc gcctcttaga tgaaatgagg
8341 agataaacta aacattaaaa tgatgaagga aaaaaaatta tttggaagca gaaaaccaca
8401 tgggtgggga aacatcagga acgaaatcag acacactgac tcaaaccacg caagggtttg
8461 agaagcccac ccctctaatt ccaggtgttt gtaatttctg cacttcgcac ttgagagaag
8521 gcagaggtgg tccgtgggaa agctccggga aacagccgtc tttcatcctt gccacattga
8581 aaaatgtcca caattttatg aattgctgtc ctaaccctgg cgtttttatc cagtgttaaa
8641 ataaattatt tcaagtttca atgtaaacac ttaacagatg acttctttgc agaagaaatg
8701 ttcgttacct actatcaaac tactttttaa cagattttgt atatacacac acaagttgac
8761 agaggtttac ctccctactt tcttagattt tatgtaactc ttttcattgg tgcttattca
8821 gaacctgaaa gccttgggca tccaagcttt cacctactca atggaggaga ggtgataatg
8881 aatgaaaaga ttgacaccag gtttcttgga caaatttaag ttcaaattta tctctttcaa
8941 gtagaccatg gtctccctag agagtgtgtt ggcttgtgtc tgccagtacg acaaaggacg
9001 ctcccagctt gatcgtggta ccttatggaa gccactcacg cattctctga tttaccccca
9061 aaacactacc atgccccagc cccactcatt taaataatac aatcatatca ctttcaaagg
9121 gctcagcacg aatgttcccc tcactccact ttttaactcg tttgctgaac tcgacaaggc
9181 ttccccttac gagcagtgag acctaggcta ctttcgaacg cttccttccg aacggtaagc
9241 cacttcgctc tcgggcagga caggtcctcc ctgcagagag agacaactca tcccccgacc
9301 ttccatacta cagaccaaaa tacccaggtg tggcctaagg actatattaa atgcctccta
9361 tagaaattca aggaatgtta gaaccaggaa actagctgtt taaagtttta aagaagtata
9421 taaatatata tataaatata aatatgaaat catatcgagt gtgaggatga gcagagtgcc
9481 aaatattcag catctgtaca aagtcattca ctggaattca actattttat gtcattctct
9541 ttctcacgct tttatggttc ttttgataaa ttctatttag tagcatgcag gatacctaat
9601 ctgaatgtgc aatatgctat tcatcaccac gacaatttct tacttcctct taataactta
9661 ccagaatgtt ggtcattcct ttaaggcagt taaggattgc tttatttgtg ttcttttttc
9721 ccatgacttt ttttcactct cagctgactg taagaaactg tgcaccgttt ccgccataac
9781 cgtcctgtga cgatgcctcc atttgacttc tgtatcgctg atgttcacct cctgtaaata
9841 gtttggcaat taaatttttt gagaaaagta atgtttactt ttttattgga gtgaattctc
9901 gtgttatttt aatctcagaa aaattatata gaccaaagag ttttatccga aaaaaaatta
9961 cactcttcct ccattatata tttcattgtt gaaatatcct caatttctct atattttaag
10021 aagtaatgga catttattaa ggttacagat ttaatatgta tgcaaaatgg tatagattaa
10081 atgagttttt aattaataaa tcctacagta tttagttmaa aaaaaa
//