LOCUS AF118767 3927 bp mRNA linear HUM 14-JUL-1999
DEFINITION Homo sapiens endothelial lipase mRNA, complete cds.
ACCESSION AF118767
VERSION AF118767.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3927)
AUTHORS Hirata,K., Dichek,H.L., Cioffi,J.A., Choi,S.Y., Leeper,N.J.,
Quintana,L., Kronmal,G.S., Cooper,A.D. and Quertermous,T.
TITLE Cloning of a unique lipase from endothelial cells extends the
lipase gene family
JOURNAL J. Biol. Chem. 274 (20), 14170-14175 (1999)
PUBMED 10318835
REFERENCE 2 (bases 1 to 3927)
AUTHORS Hirata,K., Dichek,H.L., Cioffi,J.A., Choi,S.Y., Leeper,M.J.,
Quintana,L., Kronmal,G.S., Cooper,A.D. and Quertermous,T.
TITLE Direct Submission
JOURNAL Submitted (07-JAN-1999) Cardiovascular Med., Stanford Univ., 300
Pasteur Drive, Stanford, CA 94305, USA
FEATURES Location/Qualifiers
source 1..3927
/db_xref="H-InvDB:HIT000070186"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_type="endothelial"
CDS 253..1755
/note="EL"
/codon_start=1
/product="endothelial lipase"
/protein_id="AAD30434.1"
/translation="MSNSVPLLCFWSLCYCFAAGSPVPFGPEGRLEDKLHKPKATQTE
VKPSVRFNLRTSKDPEHEGCYLSVGHSQPLEDCSFNMTAKTFFIIHGWTMSGIFENWL
HKLVSALHTREKDANVVVVDWLPLAHQLYTDAVNNTRVVGHSIARMLDWLQEKDDFSL
GNVHLIGYSLGAHVAGYAGNFVKGTVGRITGLDPAGPMFEGADIHKRLSPDDADFVDV
LHTYTRSFGLSIGIQMPVGHIDIYPNGGDFQPGCGLNDVLGSIAYGTITEVVKCEHER
AVHLFVDSLVNQDKPSFAFQCTDSNRFKKGICLSCRKNRCNSIGYNAKKMRNKRNSKM
YLKTRAGMPFRVYHYQMKIHVFSYKNMGEIEPTFYVTLYGTNADSQTLPLEIVERIEQ
NATNTFLVYTEEDLGDLLKIQLTWEGASQSWYNLWKEFRSYLSQPRNPGRELNIRRIR
VKSGETQRKLTFCTEDPENTSISPGRELWFRKCRDGWRMKNETSPTVELP"
BASE COUNT 957 a 925 c 970 g 1075 t
ORIGIN
1 agcagcgagt ccttgcctcc cggcggctca ggacgagggc agatctcgtt ctggggcaag
61 ccgttgacac tcgctccctg ccaccgcccg ggctccgtgc cgccaagttt tcattttcca
121 ccttctctgc ctccagtccc ccagcccctg gccgagagaa gggtcttacc ggccgggatt
181 gctggaaaca ccaagaggtg gtttttgttt tttaaaactt ctgtttcttg ggagggggtg
241 tggcggggca ggatgagcaa ctccgttcct ctgctctgtt tctggagcct ctgctattgc
301 tttgctgcgg ggagccccgt accttttggt ccagagggac ggctggaaga taagctccac
361 aaacccaaag ctacacagac tgaggtcaaa ccatctgtga ggtttaacct ccgcacctcc
421 aaggacccag agcatgaagg atgctacctc tccgtcggcc acagccagcc cttagaagac
481 tgcagtttca acatgacagc taaaaccttt ttcatcattc acggatggac gatgagcggt
541 atctttgaaa actggctgca caaactcgtg tcagccctgc acacaagaga gaaagacgcc
601 aatgtagttg tggttgactg gctccccctg gcccaccagc tttacacgga tgcggtcaat
661 aataccaggg tggtgggaca cagcattgcc aggatgctcg actggctgca ggagaaggac
721 gatttttctc tcgggaatgt ccacttgatc ggctacagcc tcggagcgca cgtggccggg
781 tatgcaggca acttcgtgaa aggaacggtg ggccgaatca caggtttgga tcctgccggg
841 cccatgtttg aaggggccga catccacaag aggctctctc cggacgatgc agattttgtg
901 gatgtcctcc acacctacac gcgttccttc ggcttgagca ttggtattca gatgcctgtg
961 ggccacattg acatctaccc caatgggggt gacttccagc caggctgtgg actcaacgat
1021 gtcttgggat caattgcata tggaacaatc acagaggtgg taaaatgtga gcatgagcga
1081 gccgtccacc tctttgttga ctctctggtg aatcaggaca agccgagttt tgccttccag
1141 tgcactgact ccaatcgctt caaaaagggg atctgtctga gctgccgcaa gaaccgttgt
1201 aatagcattg gctacaatgc caagaaaatg aggaacaaga ggaacagcaa aatgtaccta
1261 aaaacccggg caggcatgcc tttcagagtt taccattatc agatgaaaat ccatgtcttc
1321 agttacaaga acatgggaga aattgagccc accttttacg tcacccttta tggcactaat
1381 gcagattccc agactctgcc actggaaata gtggagcgga tcgagcagaa tgccaccaac
1441 accttcctgg tctacaccga ggaggacttg ggagacctct tgaagatcca gctcacctgg
1501 gagggggcct ctcagtcttg gtacaacctg tggaaggagt ttcgcagcta cctgtctcaa
1561 ccccgcaacc ccggacggga gctgaatatc aggcgcatcc gggtgaagtc tggggaaacc
1621 cagcggaaac tgacattttg tacagaagac cctgagaaca ccagcatatc cccaggccgg
1681 gagctctggt ttcgcaagtg tcgggatggc tggaggatga aaaacgaaac cagtcccact
1741 gtggagcttc cctgagggtg cccgggcaag tcttgccagc aaggcagcaa gacttcctgc
1801 tatccaagcc catggaggaa agttactgct gaggacccac ccaatggaag gattcttctc
1861 agccttgacc ctggagcact gggaacaact ggtctcctgt gatggctggg actcctcgcg
1921 ggaggggact gcgctgctat agctcttgct gcctctcttg aatagctcta actccaaacc
1981 tctgtccaca cctccagagc accaagtcca gatttgtgtg taagcagctg ggtgcctggg
2041 gcctctcgtg cacactggat tggtttctca gttgctgggc gagcctgtac tctgcctgac
2101 gaggaacgct ggctccgaag aggccctgtg tagaaggctg tcagctgctc agcctgcttt
2161 gagcctcagt gagaagtcct tccgacagga gctgactcat gtcaggatgg caggcctggt
2221 atcttgctcg ggccctagct gttggggttc tcatgggttg cactgaccat actgcttacg
2281 tcttagccat tccgtcctgc tccccagctc actctctgaa gcacacatca ttggctttcc
2341 tatttttctg ttcatttttt aattgagcaa atgtctattg aacacttaaa attaattaga
2401 atgtggtaat ggacatatta ctgagcctct ccatttggaa cccagtggag ttgggatttc
2461 tagaccctct ttctgtttgg atggtgtatg tgtatatgca tggggaaagg cacctggggc
2521 ctgggggagg ctataggata taagcattag ggaccctgag gctttaagtg gtttctattt
2581 cttcttagtt attatgtgcc accttcttag ttattatgtg ccacctcccc tatgagtgac
2641 gtgtttgatc actagcagaa tagcaagcag agtatcattc atgctggggc cagaatgatg
2701 gccggttgcc agatataact gctttggagc aaatctcttc tgtttagaga gatagaagtt
2761 atgacatatg taatacacat ctgtgtacac agaaaccggc acctgccaga cagagctggt
2821 tctaagattt aatacagtgc tttttttcct ctttgaaata ttttacttta ataccagtgc
2881 cttttcttgt tgaacttctt ggaaaagcca ccaattctag atcttgattt gaattaatac
2941 acacaatatc tgagacactt acacttttca aaagatttgt gtatgcattg cctaattaga
3001 gtagggggag aagggcaact attattatcc ctattttaca aaactgaggc ttagtgaggt
3061 tcagccacat gcctagactt atatactagt tagtggtgca gccagggaga ggactcagat
3121 ttcctggagg caaagtctat ctctgaaact ccatgaagac ttttgcagcc agttcccacc
3181 aatatgcccc agacgtgaga caaacaagga cttttttttt tatatagagc catccataaa
3241 atcctaagcc cttttattaa tgtataacca ggagaacatc tgtgccaacg gttggacttt
3301 ttatggctga gattcgggag gaagtgtgac accaagcagg agaggaagaa tgattttctt
3361 tgtacttagg ttttctaagg acattgtttt aatctgtatc gtgccaaagt tgtatcactg
3421 ttaaacttct gaagacataa ccagttgagt cttatttcaa gatatgttct caagccaatt
3481 gtgtgcttct cttgtttctg tgattgcttt ctagccaaag cgaagcttgt acaggttgag
3541 tatcccttat ccaaaatgct tggaaccaga agtgtttcaa attttagatt attttcagat
3601 tttggaatgt ttgcatatac ataatgagat attttgggaa taggacccga gcctaaacac
3661 aaaattcatt gatgtgtcag ttacacctta tccacatagc ctgagggtaa ttttatacga
3721 tattttaaat agttgtgtac atgaagcatg gtttgtggta acttatgtga ggggttttcc
3781 cattttttgt cttgttggtg ctcaaaaagt tttggatttt ggagcatttc ggattttgga
3841 tttttggatt agggttgctc aacccatatt attggctgta catcctggtc acttctgact
3901 tctgttttta ctaatggaag ctttgca
//