LOCUS AF117754 7389 bp mRNA linear HUM 03-JAN-2000
DEFINITION Homo sapiens thyroid hormone receptor-associated protein complex
component TRAP240 mRNA, complete cds.
ACCESSION AF117754
VERSION AF117754.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 7389)
AUTHORS Ito,M., Yuan,C.X., Malik,S., Gu,W., Fondell,J.D., Yamamura,S.,
Fu,Z.Y., Zhang,X., Qin,J. and Roeder,R.G.
TITLE Identity between TRAP and SMCC complexes indicates novel pathways
for the function of nuclear receptors and diverse mammalian
activators
JOURNAL Mol. Cell 3 (3), 361-370 (1999)
PUBMED 10198638
REFERENCE 2 (bases 1 to 7389)
AUTHORS Ito,M., Fondell,J.D., Yuan,C.-X. and Roeder,R.G.
TITLE Direct Submission
JOURNAL Submitted (05-JAN-1999) Laboratory of Biochemistry and Molecular
Biology, The Rockefeller University, 1230 York Avenue, New York, NY
10021-6399, USA
FEATURES Location/Qualifiers
source 1..7389
/db_xref="H-InvDB:HIT000070116"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_line="HeLa"
CDS 78..6602
/codon_start=1
/product="thyroid hormone receptor-associated protein
complex component TRAP240"
/protein_id="AAD22032.1"
/translation="MSASFVPNGASLEDCHCNLFCLADLTGIKWKKYVWQGPTSAPIL
FPVTEEDPILSSFSRCLKADVLGVWRRDQRPGRRELWIFWWGEDPVLLTLFTMTYQKK
KMECGRMDFPMNAVLCFSKAVHNLLERCLMNRNFVRIGKWFVKPYEKDEKPINKSEHL
SCSFTFFLHGDSNVCTSVEINQHQPVYLLSEEHITLAQQSNSPFQVILCPFGLNGTLT
GQAFKMSDSATKKLIGEWKQFYPISCCLKEMSEEKQEDMDWEDDSLAAVEVLVAGVRM
IYPACFVLVPQSDIPTPSPVGSTHCSSSCLGVHQVPASTRDPAMSSVTLTPPTSPEEV
QTVDPQSVQKWVKFSSVSDGFNSDSTSHHGGKIPRKLANHVVDRVWQECNMNRAQNKK
KYSASSGGLCEEATAAKVASWDFVEATQRTNCSCLRHKNLKSRNAGQQGQAPSLGQQQ
QILPKHKTNEKQEKSEEPQKRPLTPFHHRVSVSDDVGMDADSASQRLVISAPDSQVRF
SNIRTNDVAKTPQMHGTEMANSPQPPPLSPHPCDVVDEGVTKTPSTPQSQHFYQMPTP
DPLVPSKPMEDRIDSLSQSFPPQYQEAVEPTVYVGTAVNLEEDEANIAWKYYKFPKKK
DVEFLPPQLPSDKFKDDPVGPFGQESVTSVTELMVQCKKPLKVSDELVQQYQIKNQCL
SAIASDAEQEPKIDPYAFVEGDEEFLFPDKKDRQNSEREAGKKHKVEDGTSSVTVLSH
EEDAMSLFSPSIKQDAPRPTSHARPPSTSLIYDSDLAVSYTDLDNLFNSDEDELTPGS
KRSANGSDDKASCKESKTGNLDPLSCISTADLHKMYPTPPSLEQHIMGFSPMNMNNKE
YGSMDTTPGGTVLEGNSSSIGAQFKIEVDEGFCSPKPSEIKDFSYVYKPENCQILVGC
SMFAPLKTLPSQYLPLIKLPEECIYRQSWTVGKLELLSSGPSMPFIKEGDGSNMDQEY
GTAYTPQTHTSCGMPPSSAPPSNSGAGILPSPSTPRFPTPRTPRTPRTPRGAGGPASA
QGSVKYENSDLYSPASTPSTCRPLNSVEPATVPSIPEAHSLYVNLILSESVMNLFKDC
NSDSCCICVCNMNIKGADVGVYIPDPTQEAQYRCTCGFSAVMNRKFGNNSGLFLEDEL
DIIGRNTDCGKEAEKRFEALRATSAEHVNGGLKESEKLSDDLILLLQDQCTNLFSPFG
AADQDPFPKSGVISNWVRVEERDCCNDCYLALEHGRQFMDNMSGGKVDEALVKSSCLH
PWSKRNDVSMQCSQDILRMLLSLQPVLQDAIQKKRTVRPWGVQGPLTWQQFHKMAGRG
SYGTDESPEPLPIPTFLLGYDYDYLVLSPFALPYWERLMLEPYGSQRDIAYVVLCPEN
EALLNGAKSFFRDLTAIYESCRLGQHRPVSRLLTDGIMRVGSTASKKLSEKLVAEWFS
QAADGNNEAFSKLKLYAQVCRYDLGPYLASLPLDSSLLSQPNLVAPTSQSLITPPQMT
NTGNANTPSATLASAASSTMTVTSGVAISTSVATANSTLTTASTSSSSSSNLNSGVSS
NKLPSFPPFGSMNSNAAGSMSTQANTVQSGQLGGQQTSALQTAGISGESSSLPTQPHP
DVSESTMDRDKVGIPTDGDSHAVTYPPAIVVYIIDPFTYENTDESTNSSSVWTLGLLR
CFLEMVQTLPPHIKSTVSVQIIPCQYLLQPVKHEDREIYPQHLKSLAFSAFTQCRRPL
PTSTNVKTLTGFGPGLAMETALRSPDRPECIRLYAPPFILAPVKDKQTELGETFGEAG
QKYNVLFVGYCLSHDQRWILASCTDLYGELLETCIINIDVPNRARRKKSSARKFGLQK
LWEWCLGLVQMSSLPWRVVIGRLGRIGHGELKDWSCLLSRRNLQSLSKRLKDMCRMCG
ISAADSPSILSACLVAMEPQGSFVIMPDSVSTGSVFGRSTTLNMQTSQLNTPQDTSCT
HILVFPTSASVQVASATYTTENLDLAFNPNNDGADGMGIFDLLDTGDDLDPDIINILP
ASPTGSPVHSPGSHYPHGGDAGKGQSTDRLLSTEPHEEVPNILQQPLALGYFVSTAKA
GPLPDWFWSACPQAQYQCPLFLKASLHLHVPSVQSDELLHSKHSHPLDSNQTSDVLRF
VLEQYNALSWLTCDPATQDRRSCLPIHFVVLNQLYNFIMNML"
BASE COUNT 2162 a 1530 c 1550 g 2147 t
ORIGIN
1 gtttctctct ctggtcggaa gcggcggtaa tggcggatgg tgggttgtgg cgccggcggc
61 ggctgctgtg agggacgatg agtgcctcct tcgtgccgaa cggggccagc ctggaagatt
121 gtcactgtaa cctcttctgc ctggctgact tgacaggaat taagtggaaa aaatatgtat
181 ggcaaggccc aacttctgcc cctattctgt ttcctgtgac agaagaagac cccattttga
241 gcagttttag tcgctgcctt aaggcagatg tacttggtgt ttggcggcga gatcaaagac
301 ctggaagaag agaattgtgg atattttggt ggggtgaaga cccagttttg ctgaccttat
361 tcaccatgac ttatcagaag aagaagatgg aatgtgggag aatggacttt cctatgaatg
421 ccgtactctg cttttccaaa gcagttcaca atctattgga acggtgttta atgaacagga
481 attttgtacg tattggcaag tggtttgtaa agccttatga aaaagatgaa aaacctataa
541 ataaaagtga acacttgtcc tgctccttca cctttttctt gcatggagac agcaatgttt
601 gtaccagtgt ggaaattaac caacatcaac ctgtatacct tctcagtgaa gagcatatca
661 cccttgctca acagtctaat agcccatttc aagttatctt atgcccattt ggactaaatg
721 gcactctcac aggacaggca ttcaagatgt ctgattcagc tacaaaaaaa ttaattggtg
781 aatggaaaca gttctatcct atctcatgtt gcttgaagga gatgtctgaa gaaaaacagg
841 aagatatgga ttgggaagat gattctttag ctgcagtaga agttcttgtt gctggtgtcc
901 gaatgatcta cccagcatgc tttgttctag tccctcagtc agacattcct actcctagcc
961 ctgtgggatc cactcactgt tcatcttctt gcttgggtgt ccaccaagtg cctgcttcca
1021 caagagatcc tgctatgtct tcggttacgc ttacaccacc tacgtctcct gaggaagtcc
1081 aaacagttga tcctcagtct gtccagaagt gggtcaaatt ttcttcagta tctgatggct
1141 tcaactccga tagtactagc caccatggtg ggaaaatacc cagaaaatta gcaaatcatg
1201 tggtggatag agtttggcaa gaatgcaata tgaacagagc acagaacaag aagaagtatt
1261 ctgcttcatc aggtggtcta tgcgaagaag cgacagctgc taaagtggca tcctgggatt
1321 ttgttgaagc cacacaaaga acaaattgca gttgtttgag gcacaaaaat ctcaagtcaa
1381 gaaatgctgg acaacaagga caggcaccat ctttaggtca gcaacaacaa atacttccta
1441 agcacaagac caatgagaag caagaaaaga gtgaagagcc acagaaacgc cccttgactc
1501 cttttcacca tcgtgtgtct gttagtgatg atgttggcat ggacgcagat tcagccagcc
1561 aaagacttgt gatctctgct ccagacagtc aagtgagatt ttcaaatatc cgaactaatg
1621 atgtagcaaa gactcctcag atgcatggca ccgaaatggc aaattcacct caaccacccc
1681 cacttagtcc tcacccttgt gatgtggttg atgaaggagt gactaaaaca ccttcaactc
1741 ctcagagtca acatttttat caaatgccaa caccagatcc cttggttcct tctaaaccaa
1801 tggaagatag gatagacagt ttgtcccagt ctttcccacc tcaatatcag gaagctgtag
1861 aacctacagt atatgttggt acagcagtaa acttggaaga agatgaagcc aatatagcct
1921 ggaagtatta caagttccca aagaaaaaag atgtagagtt tttaccacct caacttccaa
1981 gtgataaatt caaggatgat ccagttggac cttttggaca ggaaagtgta acatcagtta
2041 cagagttaat ggtgcaatgt aagaaacctt taaaagtttc tgatgaatta gtgcagcaat
2101 atcaaattaa aaaccagtgt ctttcagcaa tagcatctga tgcagaacaa gaacctaaaa
2161 ttgatccata tgcatttgtt gaaggagatg aggaattcct ttttcctgat aaaaaagata
2221 gacaaaatag tgagagagaa gctggaaaaa aacacaaggt agaagatggg acatctagtg
2281 taacagtgtt atcacatgaa gaagatgcta tgtcattatt tagtccctct atcaagcaag
2341 atgctccacg ccctactagt catgcccgtc ctccatcaac aagtttgatt tatgactcag
2401 acctggctgt ctcttatact gaccttgata atctcttcaa ttctgatgaa gatgaactaa
2461 cacctggatc taaaagatca gcaaatggat cagatgataa agccagctgc aaggaatcaa
2521 agacaggaaa tctggacccg ttatcttgca taagcactgc agatcttcat aaaatgtatc
2581 ctacaccacc atcattggaa caacatatta tgggattttc cccaatgaat atgaataata
2641 aagaatatgg tagtatggat acaacacctg gaggaactgt tctagaagga aatagttcta
2701 gtataggagc gcagttcaaa attgaggttg atgagggatt ctgtagcccc aaaccttctg
2761 aaattaaaga tttttcttat gtctataagc ctgaaaattg tcaaattcta gtgggatgtt
2821 ccatgtttgc acctctaaaa actctaccaa gccaatatct gccccttatc aaattgccag
2881 aagagtgtat ttaccgtcag agttggactg ttggaaaatt ggaattgctt tcttcagggc
2941 cttcaatgcc attcatcaaa gagggtgatg gaagtaatat ggatcaagaa tatggcactg
3001 cttatacacc tcaaactcat acttcttgtg ggatgcctcc tagcagtgca cctcctagta
3061 acagcggagc aggaattctt ccttctccat ccacccctcg gtttccaact ccaaggactc
3121 caaggactcc tcggactcct cgtggagctg gtggacctgc tagtgctcaa ggttcagtca
3181 aatatgaaaa ttcagacttg tattcaccag cttctacccc atctacatgc agacccctta
3241 attctgttga acctgcaact gtcccttcca tccctgaagc acacagtctt tatgtaaacc
3301 tcatcctttc agaatcagtt atgaatttgt ttaaagactg taactctgat agttgttgca
3361 tctgtgtttg caacatgaac atcaagggtg ccgatgttgg agtttacatt ccagatccaa
3421 cgcaggaagc acaatatagg tgtacctgtg gcttcagtgc tgtcatgaac agaaaatttg
3481 gaaacaattc aggattattt cttgaagatg aactagatat cataggacgc aatacagact
3541 gtggcaaaga agcagaaaaa cgttttgaag ctctcagggc tacctctgct gaacatgtta
3601 atggaggact aaaggaatct gaaaaattat ctgatgattt gatattattg ctacaagatc
3661 agtgcactaa tttattttca ccctttggag cagcagacca agatcctttt cctaaaagtg
3721 gtgtaattag caattgggta cgtgttgaag agcgtgactg ttgcaatgac tgctaccttg
3781 cattagaaca tgggcgtcag ttcatggata acatgtcagg aggaaaagtt gatgaagcac
3841 ttgtgaaaag ttcatgctta cacccctggt ccaaaagaaa cgatgtgagt atgcagtgct
3901 cacaggatat acttcgaatg ctcctctctc ttcagccagt tcttcaggat gccattcaga
3961 aaaaaagaac agtaagacct tggggtgttc agggtcctct cacttggcaa caatttcata
4021 aaatggctgg ccgaggctct tatggaactg atgaatcccc agaaccactg ccaatcccca
4081 catttttgtt gggttatgat tatgattatc tggtgctttc tccatttgct cttccttatt
4141 gggagagact tatgctggaa ccctatggat ctcaaagaga tatagcctat gttgtactgt
4201 gtccagaaaa tgaagccttg ttaaatggag caaaaagctt ttttagagat cttactgcaa
4261 tatatgagtc ctgtcgatta ggtcaacata gacctgtttc tcgactgtta acagatggga
4321 tcatgagagt tggatctact gcatcaaaga aactatcaga aaagttggta gcagaatggt
4381 tttctcaggc agctgatggt aacaatgaag cattttctaa actcaagctt tatgcacaag
4441 tctgcagata tgacctaggt ccttatcttg cttccctgcc attggacagc tctctacttt
4501 cccagccaaa tttagttgcc cctacaagtc agtctttgat tactccacct cagatgacaa
4561 atactggaaa tgctaatact ccatctgcca ccttagcatc tgcagcgagc agcactatga
4621 cagtgacttc aggtgttgcc atatctactt cagttgccac agctaattca actttgacca
4681 cagcttcaac ttcatcttca tcatcctcca acttgaatag tggagtatca tcaaataaac
4741 taccttcgtt tccacccttt ggcagtatga acagtaatgc tgcaggatcc atgtctacac
4801 aagcaaatac agttcagagt ggtcagctag gagggcaaca gacatcagct ctacagacag
4861 ctgggatttc tggagaatca tcttcacttc ccactcagcc gcatcctgat gtgtctgaaa
4921 gcacgatgga tcgggataaa gtgggaatcc ccacagatgg tgattcacat gcagtcacgt
4981 atccacctgc aattgttgtt tatataattg atccttttac atacgaaaat acagacgaga
5041 gcactaactc ttctagtgtg tggacattgg ggctacttcg atgctttcta gaaatggtcc
5101 agactcttcc tcctcatatc aagagtactg tttctgtaca gattattcct tgtcagtacc
5161 tgttgcaacc tgtgaagcat gaagatagag aaatctatcc ccagcattta aaatccctgg
5221 ctttttcggc ctttacccag tgtcggaggc cacttccaac atcaaccaat gtgaaaacat
5281 tgactggctt tggtccaggt ttagccatgg aaactgccct tagaagtcct gatagaccag
5341 agtgtattcg actttatgca cctcctttta ttctggctcc agtgaaggac aaacagacag
5401 agctaggaga aacatttgga gaagctggac agaaatataa tgttcttttt gtgggatact
5461 gtttatcaca tgatcaaagg tggattcttg catcttgcac agatctatat ggagaacttt
5521 tagaaacttg tatcattaac atcgatgttc caaatagggc tcgtcggaaa aaaagttctg
5581 ctagaaaatt tggtctacag aaactttggg agtggtgctt aggacttgta caaatgagtt
5641 cattgccatg gagagttgta attggtcgtc taggaaggat tggtcatgga gaattgaaag
5701 attggagctg tttgctgagt cgtcgaaact tgcagtctct aagtaaaagg ctcaaagaca
5761 tgtgtagaat gtgtggtata tctgctgcag actcccctag cattctcagt gcttgcttgg
5821 tggcaatgga gccgcaaggc tcttttgtta ttatgccaga ttctgtgtca actggttctg
5881 tatttggaag aagcacgact ctaaatatgc agacatctca gctaaatacc ccacaggata
5941 catcatgtac tcatatactt gtgtttccta cttctgcttc tgtgcaagta gcttcagcta
6001 cttataccac tgaaaatttg gatttagctt tcaatcccaa caatgatgga gcagatggaa
6061 tgggtatctt tgatttgtta gacacaggag atgatcttga ccctgatatc attaatatcc
6121 ttcctgcttc tccaactggt tctcctgtac attctccagg atctcattac ccccatggag
6181 gtgatgcggg caagggtcag agtactgatc ggctactatc aacagaacct catgaggaag
6241 tacctaatat tcttcagcaa ccattggccc ttggttactt tgtatcaact gccaaagcag
6301 gtccattacc tgactggttc tggtcagcat gtcctcaagc acaatatcag tgtccccttt
6361 ttcttaaggc ctctttgcac ctccacgtgc cttcagtgca atctgacgag ctgcttcaca
6421 gtaaacactc ccacccactt gactcaaatc agacttcaga tgtcctcagg tttgttttgg
6481 aacagtacaa tgcactctcc tggctaacct gtgaccctgc aacccaggac agacgctcat
6541 gtctcccaat tcattttgtg gtgctgaatc agttatataa ctttattatg aatatgctgt
6601 gatcttcatt tgatggaact gtgcaagaaa agaacaagga aaaatggatg tttcgctgca
6661 ggattaagtt acaattatct tctcagtgaa ggtcatttgt gatggggtct aattcttatt
6721 acttcaacaa atattgtttt gacttggggg gaggggctat aaccctgcta tttttcattg
6781 actctattga actctttagg atgatgactg atcatacaaa acgtattata acattttcgt
6841 agcaaaatta accttttttt tttccagtca cagtatttgt gaaaagtaat gagccatagt
6901 acccagtcat gttaaatgaa tattaaaagc atggagagga aacatgagga acaatgaatt
6961 tcaacatatg gcttcagaac atgaagatgt tcttgtatgg attatagtat ctagtattca
7021 aaaatgcctg catctcttct cttatttatt gtaagttttt aaatgtataa attgtcttat
7081 atttcttaac ctcttttata aaaattttcc tagaaggttt atactgcctt cttgctttaa
7141 agcaattggt ctaaaatata tgtaatcgtc ttaattaaaa agttgcagta gggttgcttt
7201 tagagtatta tttttttgta agggggtggg tgggacagta aatttgtatt gtctcgatgt
7261 acagtttaac ggggatagag ggggaataat gtccatacca ttgtgtgtgg aggatttaca
7321 gctaagctgt agttgcagag tacatgtaca gtaatgaagt tcactgtgtt tataaattga
7381 aaaggtacc
//