LOCUS AF117221 4114 bp DNA linear HUM 04-FEB-1999
DEFINITION Homo sapiens KE4 protein (KE4) gene, complete cds.
ACCESSION AF117221
VERSION AF117221.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4114)
AUTHORS Vergara,A., Lana,I., Corella,A., de Miguel,C., Migliaccio,M. and
Encio,I.
TITLE Molecular cloning and characterization of the human KE4 gene and 5'
flanking region
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 4114)
AUTHORS Vergara,A., Corella,A., Lana,I., de Miguel,C., Migliaccio,M. and
Encio,I.
TITLE Direct Submission
JOURNAL Submitted (30-DEC-1998) Ciencias de la Salud, Universidad Publica
de Navarra, Avda. Baranain S/N, Pamplona, Navarra 31008, Spain
FEATURES Location/Qualifiers
source 1..4114
/organism="Homo sapiens"
/mol_type="genomic DNA"
/db_xref="taxon:9606"
/chromosome="6"
/map="6p21.3"
gene 1..3840
/gene="KE4"
regulatory 1..351
/regulatory_class="promoter"
/gene="KE4"
mRNA join(325..1061,1150..1318,1477..1530,1668..1832,
1965..2105,2315..2511,2946..3840)
/gene="KE4"
/product="KE4 protein"
CDS join(651..1061,1150..1318,1477..1530,1668..1832,
1965..2105,2315..2511,2946..3098)
/gene="KE4"
/note="putative membrane protein with histidine rich
charge clusters"
/codon_start=1
/product="KE4 protein"
/protein_id="AAD12305.1"
/translation="MARGLGGPHWVAVGLLTWATLGLLVAGLGGHDDLHDDLQEDFHG
HSHRHSHEDFHHGHSHAHGHGHTHESIWHGHTHDHDHGHSHEDLHHGHSHGYSHESLY
HRGHGHDHEHSHGGYGESGAPGIKQDLDAVTLWAYALGATVLISAAPFFVLFLIPVES
NSPRHRSLLQILLSFASGGLLGDAFLHLIPHALEPHSHHTLEQPGHGHSHSGQGPILS
VGLWVLSGIVAFLVVEKFVRHVKGGHGHSHGHGHAHSHTRGSHGHGRQERSTKEKQSS
EEEGKETRGVQKRRGGSTVPKDGPVRPQNAEEEKRGLDLRVSGYLNLAADLAHNFTDG
LAIGASFRGGRGLGILTTMTVLLHEVPHEVGDFAILVQSGCTKKQAMRLQLLTAVGAL
AGTAVPFSLKEEQWTVKLQVVQVLAGSCHLLQVALST"
BASE COUNT 914 a 1053 c 1150 g 997 t
ORIGIN
1 attaagcccg tcgctctgct cagtaccaaa atgacagcgc caatgtggca gccatctttg
61 tacagacggg aagtctcggc gcgagttccc gccccctcgt ctagttggaa accgaggagg
121 cggtctcctc cggcctgtta gcccgcctcg cccaccctcc cctcaaatca cctccacact
181 cgcgcatgcg tgtcagtgca ggatggattc gccgctaccg gagtgccgcc atattggtaa
241 aggcattagg gcgaaggtgg aacggaactt cctgttctcg cgggatctaa aggcgggact
301 gccacgtcca agcaaaccgg gaaaggagag gatcccggag ccggtgagaa ttctctgttt
361 tttctctacc atcctttcca ggccttttcc tcacctaatg agtcgtagag acgagggccc
421 agagagtctg taaagtggct ggtgaaagat tagtgtccca gggccctaca tccgggaggt
481 ggttcgggat aaagagaact agtcttggga acaatgtagg tgggaactta agggaatggg
541 agagcggccc atagaggtgg acggagggcg cgattggagt aaagcggacc ctgtgtaggt
601 atagagttga gtcaagtgga gtcactgcct ctgtccctct ggtcagcgtg atggccagag
661 gcctgggggg cccccactgg gtggccgtgg gactgctgac ctgggcgacc ttggggcttc
721 tggtggctgg actcgggggt catgacgacc tgcacgacga tctgcaagag gacttccatg
781 gccacagcca caggcactca catgaagatt tccaccatgg tcacagccat gcccatggtc
841 atggccacac tcacgagagc atctggcatg gacataccca cgatcacgac catggacatt
901 cacatgagga tttacaccat ggccatagcc atggctactc ccatgagagc ctctaccaca
961 gaggacatgg acatgaccat gagcatagcc atggaggcta tggggagtct ggggctccag
1021 gcatcaagca ggacctggat gctgtcactc tctgggctta tgtgagtctc caggggatgg
1081 gagagagaag ggctggttct ggattgttgg gaaactccac agtacttgac cttgactctc
1141 cctcaccagg cactgggggc cacagtgctg atctcagcag ctccattttt tgtcctcttc
1201 cttatccccg tggagtcgaa ctctccccgg catcgctctc tacttcagat cttgctcagt
1261 tttgcttccg gtgggctcct gggagatgct ttcctgcacc tcattcctca tgctcttggt
1321 aagtaacctc tgacttctac ctcaaatcta acctatttcg ttctttggag gaaaagggtt
1381 ctttctcctt tatgatccct gacctttcga tattccccca aatacacact cattgtgtca
1441 gatattccct catctggttt tccccccttc ttccagaacc tcattctcac cacactctgg
1501 agcaacccgg acatggacac tcccacagtg gtgaggaaga gacagatggg gatgggagtt
1561 ggggtgctgg ggaaggtccg tctctcccta ttcctcacct cccgcacttg aggaggagga
1621 gtctggaatg cacatctccc ttaatgtctc aatgcctcca ttcccaggcc agggccccat
1681 tctgtctgtg ggcctgtggg ttctcagtgg aattgttgcc tttcttgtcg tggagaaatt
1741 tgtgagacat gtgaaaggag gacatggtca cagtcatgga catggacacg ctcacagtca
1801 tacacgtgga agtcatggac atggaagaca aggtgagccc aggaacaact ttcctgaaag
1861 ctgacttgcc tgcctcagaa tctcctcatc ttatggccct caggagggag aggacatgtt
1921 ggaagatctg ttctccactc tgaccaactc ttttcttccc tcagagcgtt ctaccaagga
1981 gaagcagagc tcagaggaag aaggaaagga aacaagaggg gttcagaaga ggcgaggagg
2041 gagcacagta cccaaagatg ggccagtgag acctcagaac gctgaagaag aaaaaagagg
2101 cttaggtaag ggccagagtt ggtgataaat ttgggcaagg gacatcatca caaatcacat
2161 ggaatatgtg ctgtgggtaa tggcaggtat ctgagaaaca ctaaaggact gggtgtaaag
2221 tggtctctga ggggaggtgt gagaatagct gaccaagact ggaacaagtg gtgatggaag
2281 cctctgatca ttttctcttc ttgtcctgta caagacctgc gtgtgtcggg gtacctgaat
2341 ctggctgctg acttggcaca caacttcact gatggtctgg ccattggggc ttcctttcga
2401 gggggccggg gactagggat cctgaccaca atgactgtcc tgctacatga agtgccccac
2461 gaggtcgggg actttgccat cttggtccag tctggctgca ccaaaaagca ggttggtgat
2521 gtctgccaaa cacagctgcc tcaaaccctt tatctctcct cactcaccct aaacccaaac
2581 agcctcttat tagttccaaa caattcatac tgtcattgac aagtcctcta gaaatgaggg
2641 ggaagaagtt ctggttactt tgtcctttag ctcagtattt cttaaactgg tctataaacc
2701 atctgaatgg tttagtggag tcttacacac acacgcctac tcaatcagaa agtctgtgga
2761 aaggacctct gatctcttaa gatttttcag aaattgtcta ttctagactg ctccctcttc
2821 tctttttatt ttgatgttta gtttccaaat ccatgtcccc tatacctata ccccaccagc
2881 cacttctaaa ccactgataa tctttagcta ttggtgagtg cctttttctc ttttctgccc
2941 atcaggcgat gcgtctgcaa ctactgacag cagtaggggc actggcaggc acagctgtgc
3001 ccttctcact gaaggaggag cagtggacag tgaaattgca ggtggtgcag gtcctggctg
3061 ggtcctgcca tttactgcag gtggctttat ctacgtagca acagtgtctg tgttgcccga
3121 gctgctgagg gaggcatcac cattgcaatc acttctggag gtgctggggc tgctgggggg
3181 agttatcatg atggtgctga ttgcccacct tgagtgaggg gtggataaac taccctgccc
3241 caaacctcta cccctaactc caggtcaggg gtgcgtagag gttgggggcc ctggccaggg
3301 acatctgcca aaggaaggaa ctgtagcctg ggagcaatgg ttactttggc attagggcct
3361 tcaagggctg gcagtcttac agaggctgga gcggtgagaa tgagaggcca gagggaccat
3421 agtgttgggc actgtctgac catgttgcat ttggaaggct aaatggggcc atgaagaagg
3481 ctggaaggga cagggggtga tggcagccta cctggtgtcc cctaccccac ctgttctcgg
3541 agaaccaagt tgctacacag gaagttctcc aaggtccagt ttcctttctc ccaccagttg
3601 gtggaggctt cagggaagac cagagtcctg gacagagagg gtaacaggag gagtcgggga
3661 taaacatcaa acatcaatcg tgtgtcctga tttgggagtg attgggggga tggggtggga
3721 gagggttaat tggtattctc atggcctgat tttttttgtt tctattcctt ttatatcact
3781 gtgtttgaat cgagggggag gggtggtaac cggaaataaa gacctccgat cttccgcccc
3841 acatgcagtc tttgtctttt tggggggaat ggggcccctt gtcttctcca cacccggggc
3901 ccctaagcag cagtgtcggg ccacgccccc tcggtgggag gtcggcctgc gctggtggcc
3961 gcagatggcc taaggctggc gggcctttga ttggccccgg ctttgccctt gccacgccct
4021 tgcgctggga ttggcttagt gctgggattc ccacccaccc acagcccgcc atgggttcag
4081 ctccagaacc gactccgctc cgcactggcc ttgg
//