LOCUS AF117067 5133 bp mRNA linear HUM 15-MAR-2000
DEFINITION Homo sapiens rho-type GTPase-activating protein isoform 3 (ARHGAP6)
mRNA, complete cds.
ACCESSION AF117067
VERSION AF117067.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5133)
AUTHORS Prakash,S.K., Paylor,R., Jenna,S., Lamarche-Vane,N.,
Armstrong,D.L., Xu,B., Mancini,M.A. and Zoghbi,H.Y.
TITLE Functional analysis of ARHGAP6, a novel GTPase-activating protein
for RhoA
JOURNAL Hum. Mol. Genet. 9 (4), 477-488 (2000)
PUBMED 10699171
REFERENCE 2 (bases 1 to 5133)
AUTHORS Prakash,S. and Zogbhi,H.Y.
TITLE Direct Submission
JOURNAL Submitted (29-DEC-1998) Molecular and Human Genetics, Baylor
College of Medicine, 1 Baylor Plaza, Room T836, Houston, TX 77030,
USA
FEATURES Location/Qualifiers
source 1..5133
/db_xref="H-InvDB:HIT000070073"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="X"
/map="Xp22.3"
gene 1..5133
/gene="ARHGAP6"
CDS 875..3799
/gene="ARHGAP6"
/note="rhoGAPX-1"
/codon_start=1
/product="rho-type GTPase-activating protein isoform 3"
/protein_id="AAF43261.1"
/translation="MSAQSLLHSVFSCSSPASSSAASAKGFSKRKLRQTRSLDPALIG
GCGSDEAGAEGSARGATAGRLYSPSLPAESLGPRLASSSRGPPPRATRLPPPGPLCSS
FSTPSTPQEKSPSGSFHFDYEVPLGRGGLKKSMAWDLPSVLAGPASSRSASSILCSSG
GGPNGIFASPRRWLQQRKFQSPPDSRGHPYVVWKSEGDFTWNSMSGRSVRLRSVPIQS
LSELERARLQEVPFYQLQQDCDLSCQITIPKDGQKRKKSLRKKLDSLGKEKNKDKEFI
PQAFGMPLSQVIANDRAYKLKQDLQRDEQKDASDFVASLLPFGNKRQNKELSSSNSSL
SSTSETPNESTSPNTPEPAPRARRRGAMSVDSITDLDDNQSRLLEALQLSLPAEAQSK
KEKARDKKLSLNPIYRQVPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDR
GIDVSLEEEHSVHDVAALLKEFLRDMPDPLLTRELYTAFINTLLLEPEEQLGTLQLLI
YLLPPCNCDTLHRLLQFLSIVARHADDNISKDGQEVTGNKMTSLNLATIFGPNLLHKQ
KSSDKEFSVQSSARAEESTAIIAVVQKMIENYEALFMVPPDLQNEVLISLLETDPDVV
DYLLRRKASQSSSPDMLQSEVSFSVGGRHSSTDSNKASSGDISPYDNNSPVLSERSLL
AMQEDAAPGGSEKLYRVPGQFMLVGHLSSSKSRESSPGPRLGKDLSEEPFDIWGTWHS
TLKSGSKDPGMTGSSGDIFESSSLRAGPCSLSQGNLSPNWPRWQGSPAELDSDTQGAR
RTQAAAPATEGRAHPAVSRACSTPHVQVAGKAERPTARSEQYLTLSGAHDLSESELDV
AGLQSRATPQCQRPHGSGRDDKRPPPPYPGPGKPAAAAAWIQGPPEGVETPTDQGGQA
AEREQQVTQKKLSSANSLPAGEQDSPRLGDAGWLDWQRERWQIWELLSTDNPDALPET
LV"
BASE COUNT 1295 a 1416 c 1350 g 1072 t
ORIGIN
1 ggctgggctg cgaatagcgt gttcctctcc ggcggaacac acacacccgg ccttggggct
61 gtctcctgaa gctccctcct ccacggagag cgctgagcgc cgccgggaat tccatcccac
121 cgtgggcacg cagtctttgg aggtcccggg cgcagcacgc tcggtgtccc cacactgcag
181 caagacagag accccgcggg aaccttgagc ttggaacaac ccttgagcct ctgcagtcgg
241 aagagtgggc gcagcagccc agcggaggcc aggcgcgcaa cctcgggcgc cggggcaagg
301 agagagtgca gggaggcgca gctcaggcgc ccggctcagg agcgggagga agttctcgcg
361 gcgccgggag cgcggtggac gcgccctggg cgcacgccca ggcagccttc tccctggccc
421 tcgggactgt cctcgggcgg caaggaggag cttgctggag tcttagaggc catccagagc
481 cagcgagcag gagcgctgcg tctcccgcct cagctaggaa gggggagtgg cgctggcagg
541 ctggagctgg gaacccagcg agcgcctgac cttcctcctc ctcttcctga ccctcttcgc
601 gtcttgggct ccggaggaag gttctagcgg ctgcaggagg tccccagacc cattttccta
661 gaaggctggt gatggatctg ctgctcctgc cgccgccggg gcacttggag cgcaccggcg
721 gcgcgtgagc tgggctttgc tctccaccgc cctgggcaaa ccccgggcca gccccgcctg
781 gcacctttgc ctgagtccct ttcggttccc gacccaaagc caccagcgtc cagggaggga
841 ggaggaggtg gtcctcaggt gcagccccgc cgagatgtcc gcgcagagcc tgctccacag
901 cgtcttctcc tgttcctcgc ccgcttcaag tagcgcggcc tcggccaagg gcttctccaa
961 gaggaagctg cgccagaccc gcagcctgga cccggccctg atcggcggct gcgggagcga
1021 cgaggcgggc gcggagggca gtgcgcgggg agccacggcg ggccgcctct actccccatc
1081 actcccagcc gagagtctcg gccctcgctt ggcgtcctct tcccggggtc cgccccccag
1141 ggccaccagg ctaccgcctc ctggacctct ttgctcgtcc ttctccacac ccagcacccc
1201 gcaggagaag tcaccatccg gcagctttca ctttgactat gaggttcccc tgggtcgcgg
1261 cggcctcaag aagagcatgg cctgggacct gccttctgtc ctggccgggc cagccagtag
1321 ccgaagcgct tccagcatcc tctgttcatc cgggggaggc cccaatggca tcttcgcttc
1381 tcctaggagg tggctccagc agaggaagtt ccagtcccca cccgacagtc gcgggcaccc
1441 ctacgtcgtg tggaaatccg agggtgattt cacctggaac agcatgtcag gccgcagtgt
1501 gcggctgagg tcagtcccca tccagagtct ctcagagctg gagagggccc ggctgcagga
1561 agtgcctttt tatcagttgc aacaggactg tgacctgagc tgtcagatca ccattcccaa
1621 agatggacaa aagagaaaga aatctttaag aaagaaactg gattcactag gaaaggagaa
1681 aaacaaagac aaagaattca tcccacaggc atttggaatg cccttatccc aagtcattgc
1741 gaatgacagg gcctataaac tcaagcagga cttgcagagg gacgagcaga aagatgcatc
1801 tgactttgtg gcttccctcc tcccatttgg aaataaaaga caaaacaaag aactctcaag
1861 cagtaactca tctctcagct caacctcaga aacaccgaat gagtcaacgt ccccaaacac
1921 cccggaaccg gctcctcggg ctaggaggag gggtgccatg tcagtggatt ctatcaccga
1981 tcttgatgac aatcagtctc gactactaga agctttacaa ctttccttgc ctgctgaggc
2041 tcaaagtaaa aaggaaaaag ccagagataa gaaactcagt ctgaatccta tttacagaca
2101 ggtccctagg ctggtggaca gctgctgtca gcacctagaa aaacatggcc tccagacagt
2161 ggggatattc cgagttggaa gctcaaaaaa gagagtgaga caattacgtg aggaatttga
2221 ccgtgggatt gatgtctctc tggaggagga gcacagtgtt catgatgtgg cagccttgct
2281 gaaagagttc ctgagggaca tgccagaccc ccttctcacc agggagctgt acacagcttt
2341 catcaacact ctcttgttgg agccggagga acagctgggc accttgcagc tcctcatata
2401 ccttctacct ccctgcaact gcgacaccct ccaccgcctg ctacagttcc tctccatcgt
2461 ggccaggcat gccgatgaca acatcagcaa agatgggcaa gaggtcactg ggaataaaat
2521 gacatctcta aacttagcca ccatatttgg acccaacctg ctgcacaagc agaagtcatc
2581 agacaaagaa ttctcagttc agagttcagc ccgggctgag gagagcacgg ccatcatcgc
2641 tgttgtgcaa aagatgattg aaaattatga agccctgttc atggttcccc cagatctcca
2701 gaacgaagtg ctgatcagcc tgttagagac cgatcctgat gtcgtggact atttactcag
2761 aagaaaggct tcccaatcat caagccctga catgctgcag tcggaagttt ccttttccgt
2821 gggagggagg cattcatcta cagactccaa caaggcctcc agcggagaca tctcccctta
2881 tgacaacaac tccccagtgc tgtctgagcg ctccctgctg gctatgcaag aggacgcggc
2941 cccggggggc tcggagaagc tttacagagt gccagggcag tttatgctgg tgggccactt
3001 gtcgtcgtca aagtcaaggg aaagttctcc tggaccaagg cttgggaaag atctgtcaga
3061 ggagcctttc gatatctggg gaacttggca ttcaacatta aaaagcggat ccaaagaccc
3121 aggaatgaca ggttcctctg gagacatttt tgaaagcagc tccctaagag cggggccctg
3181 ctccctttct caagggaacc tgtccccaaa ttggcctcgg tggcagggga gccccgcaga
3241 gctggacagc gacacgcagg gggctcggag gactcaggcc gcagcccccg cgacggaggg
3301 cagggcccac cctgcggtgt cgcgcgcctg cagcacgccc cacgtccagg tggcagggaa
3361 agccgagcgg cccacggcca ggtcggagca gtacttgacc ctgagcggcg cccacgacct
3421 cagcgagagt gagctggatg tggccgggct gcagagccgg gccacacctc agtgccaaag
3481 accccatggg agtgggaggg atgacaagcg gcccccgcct ccatacccgg gcccagggaa
3541 gcccgcggca gcggcagcct ggatccaggg gcccccggaa ggcgtggaga cacccacgga
3601 ccagggaggc caagcagccg agcgagagca gcaggtcacg cagaaaaaac tgagcagcgc
3661 caactccctg ccagcgggcg agcaggacag tccgcgcctg ggggacgctg gctggctcga
3721 ctggcagaga gagcgctggc agatctggga gctcctgtcg accgacaacc ccgatgccct
3781 gcccgagacg ctggtctgag cccgcaccca gccgagcccc ccctgccccg agccccccgc
3841 cctccagccc aggggggacc gtgggtggtg gccactggca cacttagtgt tcttctttca
3901 cacttctcaa aagtgacaca agagaaatcc agttcaccta cagaggtaga gcactcacgc
3961 ccccgccatt gagaataagg ttccattgcg tagccagcct taggaaaaac aaacagaacc
4021 caaaccagat ggcaatgtcc aatctaaaaa cgtccctctt ggctctataa tataagatac
4081 aactcttgct tggtatagcc taaccgtatt tatgtgtctt cggttttgac tattgtgtat
4141 tctgtaacag attatgtata atcatatatg atatattcac aaagagaaaa caaaaggaac
4201 ttttaaaaaa aaaatcactt cacttatatt aagcaatgag atatactaaa caatgagatt
4261 ctatagaatg ttctagaatg tgcacaagcg ggtttctgtg cttttgccat agctttataa
4321 ctggggataa cccttccttc gataccaaac actaacaaga ggaagcagaa tatgagaagc
4381 catattttta cataggagtc agatacaaaa agaaaaatca ctgaatgctt ttagatattg
4441 aatacgtttt caggaaaatg ctaaatctga tagattacga aatatatttt tagaacttgt
4501 ttagaaagga ttcagttaac caaacaagaa aaaggcagtg cctcacaaag aaattaagaa
4561 gttgtccgtc ccacgttaca tcaaattcag ttttatatag gccatatata atatatattt
4621 ataatgtata atttttatgt atttttcaaa actacaaact ggaatccaac tataaagtgt
4681 ttaagaatct acacagaata ttcaaattat agaacatgtt ttttcccttt gccccataat
4741 cagtatttgc caaattacat gcaattcctt aaaaactaaa tcacattggt aaaaggccta
4801 cagctttgta cttacattgt gccaaaggct gaggaaatgt tttctttcga atttttatgt
4861 gtattgtaaa atgttctacc gtactttagt agtttgaagt tttcaagtgc ataactattt
4921 ttgaccagca gaaggcgata cgcttcagta ttttatgcaa ttttttttca cttcgaaggg
4981 aaagtgtatt ataaaaaaag attttttttt tttaaaacat gctactctta attttcatgt
5041 tggtgatgaa attcccagtg gtgtttctta aggttctatc ttgtgccatg atgaataaaa
5101 agttaagcaa aaaaaaaaaa aaaaaaaaaa aaa
//