LOCUS AF116508 1592 bp mRNA linear HUM 19-MAR-2001
DEFINITION Homo sapiens Ets transcription factor TEL-2a (TEL-2) mRNA, complete
cds.
ACCESSION AF116508
VERSION AF116508.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1592)
AUTHORS Gu,X., Shin,B.H., Akbarali,Y., Weiss,A., Boltax,J., Oettgen,P. and
Libermann,T.A.
TITLE Tel-2 is a novel transcriptional repressor related to the Ets
factor Tel/ETV-6
JOURNAL J. Biol. Chem. 276 (12), 9421-9436 (2001)
PUBMED 11108721
REFERENCE 2 (bases 1 to 1592)
AUTHORS Shin,B.H., Boltax,J., Gu,X., Akbarali,Y. and Libermann,T.A.
TITLE Direct Submission
JOURNAL Submitted (23-DEC-1998) Medicine, Beth Israel Deaconess Medical
Center, 330 Brookline Ave., Boston, MA 02215, USA
COMMENT Name: Tel-2a.
FEATURES Location/Qualifiers
source 1..1592
/db_xref="H-InvDB:HIT000069928"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="6"
/map="6p21"
/tissue_type="pancreas"
gene 1..1592
/gene="TEL-2"
misc_feature 76..411
/gene="TEL-2"
/note="Ets transcription factor TEL-2a pointed domain;
possibly translated; peptide identified by in vitro
translation assay"
CDS 294..1142
/gene="TEL-2"
/note="DNA-binding domain; interacts with Ets binding
sites in electrophoretic mobility shift assays"
/codon_start=1
/product="Ets transcription factor TEL-2a"
/protein_id="AAD43250.1"
/translation="MHRGARVRDERTRPLHPHQGRLPAPCAQLRSGKRTGFPLSGNPG
DVLYELLQYIKTQRRALVCGPFFGGIFRLKTPTQHSPVPPEEVTGPSQMDTRRGHLLQ
PPDPGLTSNFGHLDDPGLARWTPGKEESLNLCHCAELGCRTQGVCSFPAMPQAPIDGR
IADCRLLWDYVYQLLLDTRYEPYIKWEDKDAKIFRVVDPNGLARLWGNHKNRVNMTYE
KMSRALRHYYKLNIIKKEPGQKLLFRFLKTPGKMVQDKHSHLEPLESQEQDRIEFKDK
RPEISP"
BASE COUNT 381 a 467 c 466 g 278 t
ORIGIN
1 gcctagggcc ccagcagcca cagccagggg agcgctcaag acagaaagcc ggtggcttcc
61 tcacctccac ctgtaatgca ggagggagaa ttggctattt ctcctataag ccctgtggca
121 gccatgcctc ccctaggcac ccacgtgcaa gccagatgtg aagctcaaat taacctgctg
181 ggtgaagggg ggatctgcaa gctgccagga agactccgca tccagcccgc actgtggagc
241 agggaggacg tgctgcactg gctgcgctgg gcagagcagg agtactctct gccatgcacc
301 gcggagcacg ggttcgagat gaacggacgc gccctctgca tcctcaccaa ggacgacttc
361 cggcaccgtg cgcccagctc aggtcaggga aacgcacagg ctttcctcta agcgggaacc
421 ctggtgacgt cctgtatgag ctgctccagt acatcaagac ccagcggcga gccctggtgt
481 gtgggccctt ttttggaggg atcttcaggc tgaagacgcc cacccagcac tctccagtcc
541 ccccggaaga ggtgactggc ccctctcaga tggacacccg aaggggccac ctgctgcagc
601 caccagaccc agggcttacc agcaacttcg gccacctgga tgaccctggc ctggcaaggt
661 ggacccctgg caaggaggag tccctcaact tatgtcactg tgcagagctc ggctgcagga
721 cccagggggt ctgttccttc cccgcgatgc cgcaggcccc cattgacggc aggatcgctg
781 actgccgcct gctgtgggat tacgtgtatc agctgctcct tgatacccga tatgagccct
841 acatcaagtg ggaagacaag gacgccaaga tcttccgagt tgtggatcca aatgggctcg
901 ccagactctg gggaaatcac aagaaccggg tgaacatgac ctacgagaag atgtctcgtg
961 ccctgcgcca ctattataag cttaatatca ttaagaagga accggggcag aaactcctgt
1021 tcagatttct aaagactccg ggaaagatgg tccaggacaa gcacagccac ctggagccgc
1081 tggagagcca ggagcaggac agaatagagt tcaaggacaa gaggccagaa atctctccgt
1141 gaggggcagg tggactccag gcacccggta ccgatggggc agggaccgag tctcccatga
1201 aggcagactc ctcctcccag cagagcagca ggatccccag ccagactctg tacccacagg
1261 attacagcca ttgcttggga aggctgggag gcctcccatc caggacactg ggggcaggag
1321 tgtcatcttt tgggcagggc aatcctgggg ctaaatgagg tacaggggaa tggactctcc
1381 cctactgcac ccctgggaga ggaagccagg caccgataga gcacccagcc ccacccctgt
1441 aaatggaatt taccagatga agggaatgaa gtccctcact gagcctcaga tttcctcacc
1501 tgtgaaatgg gctgaggcag gaaatgggaa aaagtgttag tgcttccagg cggcactgac
1561 agcctcagta acaataaaaa caatggtagc tg
//