LOCUS AF115573 2592 bp mRNA linear HUM 26-JAN-1999
DEFINITION Homo sapiens GTPase-activating protein GAP1m mRNA, complete cds.
ACCESSION AF115573
VERSION AF115573.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2592)
AUTHORS Lockyer,P.J., Bottomley,J.R., Reynolds,J.S., McNulty,T.J.,
Venkateswarlu,K., Potter,B.V., Dempsey,C.E. and Cullen,P.J.
TITLE Distinct subcellular localisations of the putative inositol
1,3,4,5-tetrakisphosphate receptors GAP1IP4BP and GAP1m result from
the GAP1IP4BP PH domain directing plasma membrane targeting
JOURNAL Curr. Biol. 7 (12), 1007-1010 (1997)
PUBMED 9382842
REFERENCE 2 (bases 1 to 2592)
AUTHORS Lockyer,P.J.
TITLE Direct Submission
JOURNAL Submitted (21-DEC-1998) Biochemistry, University of Bristol,
University Walk, Bristol BS8 1TD, UK
FEATURES Location/Qualifiers
source 1..2592
/db_xref="H-InvDB:HIT000069912"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/tissue_type="blood"
CDS 1..2550
/function="inositol 1,3,4,5-tetrakisphosphate-binding
protein"
/codon_start=1
/product="GTPase-activating protein GAP1m"
/protein_id="AAD09821.1"
/translation="MAAAAPAAAAASSEAPAASATAEPEAGDQDSREVRVLQSLRGKI
CEAKNLLPYLGPHKMRDCFCTINLDQEEVYRTQVVEKSLSPFFSEEFYFEIPRTFQYL
SFYVYDKNVLQRDLRIGKVAIKKEDLCNHSGKETWFSLQPVDSNSEVQGKVHLELKLN
ELITENGTVCQQLVVHIKACHGLPLINGQSCDPYATVSLVGPSRNDQKKTKVKKKTSN
PQFNEIFYFEVTRSSSYTRKSQFQVEEEDIEKLEIRIDLWNNGNLVQDVFLGEIKVPV
NVLRTDSSHQAWYLLQPRDNGNKSSKTDDLGSLRLNICYTEDYVLPSEYYGPLKTLLL
KSPDVQPISASAAYILSEICRDKNDAVLPLVRLLLHHDKLVPFATAVAELDLKDTQDA
NTIFRGNSLATRCLDEMMKIVGGHYLKVTLKPILDEICDSSKSCEIDPIKLKEGDNVE
NNKENLRYYVDKLFNTIVKSSMSCPTVMCDIFYSLRQMATQRFPNDPHVQYSAVSSFV
FLRFFAVAVVSPHTFHLRPHHPDAQTIRTLTLISKTIQTLGSWGSLSKSKSSFKETFM
CEFFKMFQEEGYIIAVKKFLDEISSTETKESSGTSEPVHLKEGEMYKRAQGRTRIGKK
NFKKRWFCLTSRELTYHKQPGKDAIYTIPVKNILAVEKLEESSFNKKNMFQVIHTEKP
LYVQANNCVEANEWIDVLCRVSRCNQNRLSFYHPSVYLNGNWLCCQETGENTLGCKPC
TAGVPADIQIDIDEDRETERIYSLFTLSLLKLQKMEEACGTIAVYQGPQKEPDDYSNF
VIEDSVTTFKTIQQIKSIIEKLDEPHEKYRKKRSSSAKYGSKENPIVGKAS"
BASE COUNT 855 a 488 c 559 g 690 t
ORIGIN
1 atggcggcgg cggcgcctgc tgctgcggcg gcttcttccg aggcgccagc ggcgagtgcg
61 actgcagagc ccgaggccgg ggaccaggac agtcgcgagg ttcgagtgtt gcagagcctg
121 cggggcaaga tctgtgaagc aaaaaattta ttgccatatc ttggacccca caaaatgaga
181 gattgtttct gtaccataaa tttggaccag gaagaagttt atcgtaccca agttgtggaa
241 aaatctttaa gcccattttt cagtgaagaa ttttactttg agattccaag aactttccag
301 tatttgtctt tctatgttta tgataagaat gttttacaaa gagatctccg tataggaaaa
361 gtagccatca aaaaagaaga cttgtgtaat cacagtggca aagaaacttg gttttcatta
421 cagcctgttg actccaattc agaggttcag ggtaaagttc accttgaatt aaaactgaat
481 gaactgataa cggagaatgg aactgtatgc cagcagcttg ttgtacacat caaggcatgc
541 catgggttgc ctctcataaa tggccaaagc tgtgaccctt atgcaacagt ttctctagtg
601 ggcccttcta ggaatgacca aaagaagaca aaagtaaaga agaaaacaag caatccgcag
661 tttaatgaaa tcttttattt tgaagtaacc agatccagta gttacaccag aaagtcccag
721 ttccaggtag aagaggagga cattgaaaag ctagaaatca ggatcgactt gtggaacaat
781 ggaaacctag tccaagatgt tttcctaggt gagattaagg ttcctgtgaa cgtattaaga
841 actgattcct ctcatcaagc ctggtacttg ctacagccaa gagacaatgg aaacaagtca
901 tccaaaactg atgacctggg gtctcttcga ttaaatatat gttatacaga agactacgtg
961 cttccttcag agtactatgg tcctttgaaa actttgctgc taaaatcacc agatgttcaa
1021 ccaatatctg cctcagctgc ttacattttg agtgaaatat gtcgagataa aaatgatgct
1081 gttttgcccc ttgtacgact gctgctgcac catgataaac ttgttccttt tgccactgct
1141 gtggctgaat tagacttgaa ggatacacaa gatgcaaaca caatttttag aggaaattcc
1201 ctggctaccc gatgtctgga tgagatgatg aaaatagtgg gagggcacta cctgaaagta
1261 acattaaaac ctattcttga tgagatatgt gactcctcaa aatcctgtga aatcgatcct
1321 attaaattga aagagggaga taatgtagaa aataataagg agaatctgcg ctactatgta
1381 gacaagttat tcaatacaat tgtaaaatca agtatgagct gccccactgt aatgtgtgat
1441 atcttttatt ctctaaggca gatggctact cagagatttc ctaatgaccc tcatgttcag
1501 tattctgcag tgagcagctt tgtatttctt cgtttctttg ctgtagccgt agtatcacct
1561 catacttttc atttgcgacc tcatcatcca gatgcacaga caattagaac attaactctc
1621 atctcaaaaa ctatacaaac tttgggaagc tgggggagtc tgtccaaaag caagtcaagt
1681 ttcaaagaga cattcatgtg tgaatttttc aaaatgtttc aagaagaagg atatattata
1741 gcagttaaaa agttcttgga tgaaatttca tctactgaaa ctaaagagtc cagtggtacg
1801 agtgagcctg tgcacctgaa agaaggtgag atgtataaaa gagctcaagg aagaactcgg
1861 attggaaaaa agaattttaa gaaacgatgg ttctgcttaa caagcagaga gctcacctac
1921 cacaaacagc caggcaaaga tgcaatctac acaatcccag taaaaaacat tcttgctgtg
1981 gaaaaactgg aagagagctc tttcaacaag aaaaatatgt tccaagtaat acatacggag
2041 aaaccactct atgtccaggc aaataactgt gtagaagcta atgaatggat agacgtactc
2101 tgcagggtga gccgatgcaa tcaaaacagg ctcagttttt atcatccctc tgtgtatcta
2161 aacggaaatt ggctctgctg tcaggagact ggtgaaaaca ctctcggctg caagccatgt
2221 actgcaggtg tccctgcaga catccaaata gatattgatg aagacagaga aacagaaaga
2281 atttattccc tttttaccct cagtttactt aagctgcaga agatggaaga ggcttgtgga
2341 actattgcag tctatcaagg accacagaaa gagcctgatg attattctaa ctttgtaatc
2401 gaggattctg taacaacctt taagacaatt cagcaaataa aaagcataat tgagaagctg
2461 gatgaacctc atgaaaaata taggaagaaa agatccagta gtgcaaaata tgggagcaag
2521 gaaaatccaa ttgttgggaa agcatcttag agtttaacag attggttcag aagaactgga
2581 aaatattatt tt
//