LOCUS AF114491 3220 bp mRNA linear HUM 03-AUG-2000
DEFINITION Homo sapiens EGF-like module EMR2 (EMR2) mRNA, complete cds.
ACCESSION AF114491
VERSION AF114491.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3220)
AUTHORS Lin,H.H., Stacey,M., Hamann,J., Gordon,S. and McKnight,A.J.
TITLE Human EMR2, a novel EGF-TM7 molecule on chromosome 19p13.1, is
closely related to CD97
JOURNAL Genomics 67 (2), 188-200 (2000)
PUBMED 10903844
REFERENCE 2 (bases 1 to 3220)
AUTHORS Lin,H.-H., McKnight,A.J., Stacey,M. and Gordon,S.
TITLE Direct Submission
JOURNAL Submitted (16-DEC-1998) Sir William Dunn School of Pathology,
Oxford University, South Parks Road, Oxford OX1 3RE, United Kingdom
FEATURES Location/Qualifiers
source 1..3220
/db_xref="H-InvDB:HIT000069840"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="19"
/map="19p13.1"
/cell_type="granulocytes; monocytes; macrophages"
gene 1..3220
/gene="EMR2"
/note="EGF-TM7 gene family"
CDS 70..2541
/gene="EMR2"
/note="a seven transmembrane mucin-like hormone receptor
that contains 5 EGF-like motifs; similar to EGF-like
motifs of CD97 protein; expressed predominantly in
neutrophils and monocytes/macrophages"
/codon_start=1
/product="EGF-like module EMR2"
/protein_id="AAF21974.1"
/translation="MGGRVFLVFLAFCVWLTLPGAETQDSRGCARWCPQDSSCVNATA
CRCNPGFSSFSEIITTPMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEP
VSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKLKPEDPKL
CTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSS
GQHQCDSSTVCFNTVGSYSCRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQ
TLSRFFDKVQDLGRDYKPGLANNTIQSILQALDELLEAPGDLETLPRLQQHCVASHLL
DGLEDVLRGLSKNLSNGLLNFSYPAGTELSLEVQKQVDRSVTLRQNQAVMQLDWNQAQ
KSGDPGPSVVGLVSIPGMGKLLAEAPLVLEPEKQMLLHETHQGLLQDGSPILLSDVIS
AFLSNNDTQNLSSPVTFTFSHRSVIPRQKVLCVFWEHGQNGCGHWATTGCSTIGTRDT
STICRCTHLSSFAVLMAHYDVQEEDPVLTVITYMGLSVSLLCLLLAALTFLLCKAIQN
TSTSLHLQLSLCLFLAHLLFLVAIDQTGHKVLCSIIAGTLHYLYLATFTWMLLEALYL
FLTARNLTVVNYSSINRFMKKLMFPVGYGVPAVTVAISAASRPHLYGTPSRCWLQPEK
GFIWGFLGPVCAIFSVNLVLFLVTLWILKNRLSSLNSEVSTLRNTRMLAFKATAQLFI
LGCTWCLGILQVGPAARVMAYLFTIINSLQGVFIFLVYCLLSQQVREQYGKWSKGIRK
LKTESEMHTLSSSAKADTSKPSTVN"
BASE COUNT 754 a 934 c 776 g 756 t
ORIGIN
1 cggagacggg acagccctgt cccactcact ctttcccctg ctgctcctgc cggcagctca
61 gctggaacca tgggaggccg cgtctttctc gtctttctcg cattctgtgt ctggctgact
121 ctgccgggag ctgaaaccca ggactccagg ggctgtgccc ggtggtgccc tcaggactcc
181 tcgtgtgtca atgccaccgc ctgtcgctgc aatccagggt tcagctcttt ttctgagatc
241 atcaccaccc ccatggagac ttgtgacgac atcaacgagt gtgcaacact gtcgaaagtg
301 tcatgcggaa aattctcgga ctgctggaac acagagggga gctacgactg cgtgtgcagc
361 ccaggatatg agcctgtttc tggggcaaaa acattcaaga atgagagcga gaacacgtgt
421 caagatgtgg acgaatgtca gcagaaccca aggctctgta aaagctacgg cacctgcgtc
481 aacaccctcg gcagctacac gtgccagtgc ctgcctggct tcaagctcaa acctgaggac
541 ccgaagctct gcacagatgt gaatgaatgc acctccggac aaaacccatg ccacagctcc
601 acccactgcc tcaacaacgt gggcagctat cagtgccgct gccgcccggg ctggcaaccg
661 attccggggt cccccaatgg cccaaacaat accgtctgtg aagatgtgga cgagtgcagc
721 tccgggcagc atcagtgtga cagctccacc gtctgcttca acaccgtggg ttcatacagc
781 tgccgctgcc gcccaggctg gaagcccaga cacggaatcc cgaataacca aaaggacact
841 gtctgtgaag atatgacttt ctccacctgg accccgcccc ctggagtcca cagccagacg
901 ctttcccgat tcttcgacaa agtccaggac ctgggcagag actacaagcc aggcttggcc
961 aataacacca tccagagcat cttacaggcg ctggatgagc tgctggaggc ccctggggac
1021 ctggagaccc tgccccgctt acagcagcac tgtgtggcca gtcacctgct ggatggccta
1081 gaggatgtcc tcagaggcct gagcaagaac ctttccaatg ggctgttgaa cttcagttat
1141 cctgcaggca cagaattgtc cctggaggtg cagaagcaag tagacaggag tgtcaccttg
1201 agacagaatc aggcagtgat gcagctcgac tggaatcagg cacagaaatc tggtgaccca
1261 ggcccttctg tggtgggcct tgtctccatt ccagggatgg gcaagttgct ggctgaggcc
1321 cctctggtcc tggaacctga gaagcagatg cttctgcatg agacacacca gggcttgctg
1381 caggacggct cccccatcct gctctcagat gtgatctctg cctttctgag caacaacgac
1441 acccaaaacc tcagctcccc agttaccttc accttctccc accgttcagt gatcccgaga
1501 cagaaggtgc tctgtgtctt ctgggagcat ggccagaatg gatgtggtca ctgggccacc
1561 acaggctgca gcacaatagg caccagagac accagcacca tctgccgttg cacccacctg
1621 agcagctttg ccgtcctcat ggcccactac gatgtgcagg aggaggatcc cgtgctgact
1681 gtcatcacct acatggggct gagcgtctct ctgctgtgcc tcctcctggc ggccctcact
1741 tttctcctgt gtaaagccat ccagaacacc agcacctcac tgcatctgca gctctcgctc
1801 tgcctcttcc tggcccacct cctcttcctc gtggcaattg atcaaaccgg acacaaggtg
1861 ctgtgctcca tcatcgccgg taccttgcac tatctctacc tggccacctt cacctggatg
1921 ctgctggagg ccctgtacct cttcctcact gcacggaacc tgacggtggt caactactca
1981 agcatcaaca gattcatgaa gaagctcatg ttccctgtgg gctacggagt cccagctgtg
2041 acagtggcca tttctgcagc ctccaggcct cacctttatg gaacaccttc ccgctgctgg
2101 ctccaaccag aaaagggatt tatatggggc ttccttggac ctgtctgcgc catcttctct
2161 gtgaatttag ttctctttct ggtgactctc tggattttga aaaacagact ctcctccctc
2221 aatagtgaag tgtccaccct ccggaacaca aggatgctgg catttaaagc gacagctcag
2281 ctgttcatcc tgggctgcac gtggtgtctg ggcatcttgc aggtgggtcc ggctgcccgg
2341 gtcatggcct acctcttcac catcatcaac agcctgcagg gtgtcttcat cttcctggtg
2401 tactgcctcc tcagccagca ggtccgggag caatatggga aatggtccaa agggatcagg
2461 aaattgaaaa ctgagtctga gatgcacaca ctctccagca gtgctaaggc tgacacctcc
2521 aaacccagca cggttaacta gaaaaatctt ctgaataaga tcttccctct ttgccggtgg
2581 aaaatctgaa caatctttga gccatctaga ggggaaagaa aagactttgt tctgtgtgtt
2641 tcaagaaatt caccatgtca gcaatatgaa ggatgttatg gaaggcgtgc ttggcattca
2701 attcctgcag aaaccggaaa tcttccatgc cctgcaatgt gctcatcaaa ctctcagcat
2761 atggacggcc agctgtggcc catatcttgg tcactctgaa gcacaatatt tatgaagcta
2821 tagaacgtta agacctcttt cacagcctct ccttcctaca aagactcctc caaatcttaa
2881 aatgaagcag gaaaacaagc ctaagaggac tttcataccg acaacatctg aaaggactag
2941 aatgttcaca ccacgatctg gatttcttaa ttttttgttt ttgtttttgt tgttctctag
3001 ttctacgggt ttgattattt agtcatgtga aaaatattga ttactcacac atagatcaag
3061 agagacacgg ctcctgcctt catggagctt ttaggggaaa atgaagtggc tcttgcagct
3121 agagttgact cagaagccga aattcctaga aatcaggttt ctactgctag gcaattgaag
3181 tataaactat tttataaaca ctgtcttctt tcatcttcac
//