LOCUS AF113616 10708 bp DNA linear HUM 26-JUL-2016
DEFINITION Homo sapiens intestinal mucin 3 (MUC3) gene, partial cds.
ACCESSION AF113616
VERSION AF113616.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 10708)
AUTHORS Crawley,S.C., Gum,J.R. Jr., Hicks,J.W., Pratt,W.S., Aubert,J.P.,
Swallow,D.M. and Kim,Y.S.
TITLE Genomic organization and structure of the 3' region of human MUC3:
alternative splicing predicts membrane-bound and soluble forms of
the mucin
JOURNAL Biochem. Biophys. Res. Commun. 263 (3), 728-736 (1999)
PUBMED 10512748
REFERENCE 2 (bases 1 to 10708)
AUTHORS Crawley,S.C., Gum,J.R., Hicks,J.W., Pratt,W.S., Aubert,J.-P.,
Swallow,D.M. and Kim,Y.S.
TITLE Direct Submission
JOURNAL Submitted (14-DEC-1998) GI Research, VAMC-SF, 4150 Clement Street,
San Francisco, CA 94121, USA
FEATURES Location/Qualifiers
source 1..10708
/organism="Homo sapiens"
/mol_type="genomic DNA"
/db_xref="taxon:9606"
/chromosome="7"
/map="7q22"
/tissue_type="intestine"
gene <1..9939
/gene="MUC3"
mRNA join(<1..2549,2656..2841,4757..4872,5292..5356,6299..6447,
6886..6951,7307..7469,7989..8162,8255..8346,8502..8554,
8724..9939)
/gene="MUC3"
/product="intestinal mucin 3"
CDS join(<1..2549,2656..2841,4757..4872,5292..5356,6299..6447,
6886..6951,7307..7469,7989..8162,8255..8346,8502..8554,
8724..8765)
/gene="MUC3"
/codon_start=2
/product="intestinal mucin 3"
/protein_id="AAF13032.1"
/translation="ITITETTSHSTPSYTTSITTTETPSHSTPSYTTSITTTETPSHS
TPSFTSSITTTETTSHSTPSFTSSIRTTETTSYSTPSFTSSNTITETTSHSTPSYITS
ITTTETPSSSTPSFSSSITTTETTSHSTPGFTSSITTTETTSHSTPSFTSSITTTETT
SHDTPSFTSSITTSETPSHSTPSSTSLITTTKTTSHSTPSFTSSITTTETTSHSARSF
TSSITTTETTSHNTRSFTSSITTTETNSHSTTSFTSSITTTETTSHSTPSFSSSITTT
ETPLHSTPGLTSWVTTTKTTSHITPGLTSSITTTETTSHSTPGFTSSITTTETTSEST
PSLSSSTIYSTVSTSTTAITSHFTTSETAVTPTPVTPSSLSTDIPTTSLRTLTPSSVG
TSTSLTTTTDFPSIPTDISTLPTRTHIISSSPSIQSTETSSLVGTTSPTMSTVRMTLR
ITENTPISSFSTSIVVIPETPTQTPPVLTSATGTQTSPAPTTVTFGSTDSSTSTLHTL
TPSTALSTIVSTSQVPIPSTHSSTLQTTPSTPSLQTSLTSTSEFTTESFTRGSTSTNA
ILTSFSTIIWSSTPTIIMSSSPSSASITPVFSTTIHSVPSSPYIFSTENVGSASITGF
PSLSSSATTSTSSTSSSLTTALTEITPFSYISLPSTTPCPGTITITIVPASPTDPCVE
MDPSTEATSPPTTPLTVFPFTTEMVTCPTSISIQTTLTTYMDTSSMMPESESSISPNA
SSSTGTGTVPTNTVFTSTRLPTSETWLSNSSVIPLPLPGVSTIPLTMKPSSSLPTILR
TSSKSTHPSPPTTRTSETPVATTQTPTTLTSRRTTRITSQMTTQSTLTTTAGTCDNGG
TWEQGQCACLPGFSGDRCQLQTRCQNGGQWDGLKCQCPSTFYGSSCEFAVEQVDLDVV
ETEVGMEVSVDQQFSPDLNDNTSQAYRDFNKTFWNQMQKIFADMQGFTFKGVEILSLR
NGSIVVDYLVLLEMPFSPQLESEYEQVKTTLKEGLQNASQDVNSCQDSQTLCFKPDSI
KVNNNSKTELTPAAICRRAAPTGYEEFYFPLVEATRLRCVTKCTSGVDNAIDCHQGQC
VLETSGPTCRCYSTDTHWFSGPRCEVAVHWRALVGGLTAGAALLVLLLLALGVRAVRS
GWWGGQRRGRSWDQDRKWFETWDEEVVGTFSNWGFEDDGTDKDTNFYVALENVDTTMK
VHIKRPEMTSSSV"
misc_feature 8053..8127
/gene="MUC3"
/note="Region: membrane spanning domain"
repeat_region 1..1021
/gene="MUC3"
/rpt_type=tandem
/rpt_unit_range=1..51
BASE COUNT 2202 a 3424 c 2471 g 2609 t
ORIGIN
1 gatcaccatc accgagacca cctcacacag tactcccagc tacactacct caatcaccac
61 caccgagacc ccctcacaca gtactcccag ctacactacc tcaatcacca ccaccgagac
121 cccatcacac agtactccca gcttcacttc ttcaatcacc accaccgaga ccacatccca
181 cagtactccc agcttcactt cttcaatcag gaccaccgag accacatcct acagtactcc
241 cagcttcact tcttcaaata ccatcactga gaccacctca cacagtactc ccagctacat
301 tacctcaatc accaccaccg agaccccctc aagcagtact cccagcttca gttcttcgat
361 caccaccact gagaccacat cccacagtac tcccggcttc acttcttcaa tcaccaccac
421 tgagactaca tcccacagta ctcccagctt cacttcttcg atcaccacca ctgagaccac
481 ctcacatgat actcccagct tcacttcttc aatcaccacc agtgagaccc cctcacacag
541 tactcccagc tccacttctt taatcaccac caccaagacc acctcacaca gtactcccag
601 cttcacttct tcgatcacca ccaccgagac cacctcacac agtgctcgca gcttcacttc
661 ttcgatcacc accaccgaga ccacctcaca caatactcgg agcttcactt cttcgatcac
721 caccaccgag accaactctc acagtactac cagcttcact tcttcgatca ccaccaccga
781 gaccacctca cacagtactc ccagcttcag ttcttcaatc accaccactg agaccccctt
841 acacagtact cctggcctca cttcgtgggt caccaccacc aagaccacct cacacattac
901 tcctggcctc acttcttcaa tcaccaccac tgagactacc tcacacagta ctcccggctt
961 cacttcttca atcaccacca ctgagaccac ctcagagagt actcccagcc tcagttcttc
1021 aaccatctac tccacagtca gcacatccac aactgccatc acctcacatt ttactacctc
1081 agagactgcg gtgactccca cacctgtaac cccatcttct ctgagtacag acatcccgac
1141 cacaagccta cgaactctca ccccttcgtc tgtgggcacc agcacttcat tgactacaac
1201 cacagacttt ccctctatac ccactgatat cagtacctta ccaactcgaa cacacatcat
1261 ttcatcttct ccctccatcc aaagtacaga aacctcatcc cttgtgggca ccacctctcc
1321 caccatgtcc actgtgagaa tgaccctcag aattactgag aacaccccaa tcagttcctt
1381 tagcacaagt attgttgtta tacctgaaac cccaacacag acccctcctg tactgacgtc
1441 agccactggg acccaaacat ctcctgcacc tactactgtc acctttggaa gtacggattc
1501 ctccacgtcc actcttcata ctcttactcc atcaacagcc ttgagcacga tcgtgtcaac
1561 atcacaggtt cctattccta gcacacattc ctccaccctt caaacaactc cttctactcc
1621 ctcattgcaa acttcactca catctacaag tgagttcact acagaatctt tcactagggg
1681 aagtacgtct acaaatgcaa tcttgacttc ttttagtacc atcatctggt cctcaacacc
1741 cactattatc atgtcctctt ctccatcttc tgccagcata actccagtgt tctccactac
1801 cattcattct gttccttctt caccatacat tttcagtaca gaaaatgtgg gctccgcttc
1861 tatcacaggc tttcctagtc tctcttcctc tgcaactacc agcacttctt caaccagctc
1921 ctctctgacc acagctctca ctgaaataac ccccttttct tatatttccc ttccctccac
1981 cacaccctgt ccaggaacta taacaattac catagtccct gcctctccca ctgatccatg
2041 tgttgaaatg gatcccagca ctgaagctac ttctcctccc accaccccat taacagtctt
2101 tccctttact accgaaatgg tcacctgtcc tacctccatc agtatccaaa ctactcttac
2161 tacatatatg gacacttctt ccatgatgcc agaaagtgag tccagcatct cacccaatgc
2221 ttccagttcc actggcactg ggactgtacc cacaaacaca gttttcacaa gtactcgact
2281 gcccaccagt gagacctggc tgagcaacag ttctgtgatc cccctacctc ttcctggcgt
2341 ctctaccatc ccgctcacca tgaaaccaag cagtagcctc ccgaccatcc tgaggacttc
2401 aagcaagtca acacacccat ccccacccac cactaggact tcagagacac cagtggccac
2461 tacccagact cctaccaccc ttacatcacg caggacaact cgcatcactt ctcagatgac
2521 cacacagtcc acgttgacca ccactgcagg ttggaccttc tgcctctctg ttcccctcct
2581 tcctcccctg caaaattcct gtgtcactga ggtgaggctt tatcctgagc ttccctttct
2641 ttctgtgttt tccaggcacc tgtgacaatg gtggcacctg ggaacaggga cagtgtgctt
2701 gccttccggg gttttctggg gaccgctgtc agctccagac cagatgccag aatgggggtc
2761 agtgggatgg cctcaaatgc cagtgcccca gcaccttcta tggttccagt tgtgagtttg
2821 ctgtggaaca ggtggatcta ggtgagttgc cagagctatg ccttctgcac ttcctcccac
2881 agggtgtcac tgactctccc cagacttatc cctctgtggg gcctggaggc acccatgcct
2941 ttttgcccgg tccttccctc cctgccatct ctcccatgcc ctccgctgcc ctgtgtcatg
3001 ctcctctccg tcctcaccct taggaggtgg ctgggactac cctccctcct gggcccatct
3061 cctgacttgg gctgcttgga gctgtatcag tttccaactg ctgccgggcc aacaaacaca
3121 aatctggctg ctggaacaac acgacattat catgttagaa ttctgtagat taaaagtctg
3181 atgtgggtgt cactgggctg aaatcaaagc gtcaccaggg ctgtgttgtc tttcaacggc
3241 tccaggaaag aatccatttt tttgcccttt gcagcttctg gagcctccca cagcaaggct
3301 gcatctctct gtgtctttct cccatagcct catctcccta taatgaactc tggcctcctc
3361 aattgcttct cccactgtta aggacccttg tgataacttt gcctcctccc caaatagtct
3421 atgttaattt tctcaagatc agctgattac gccgggcggg gtggctcaca cctgtaatcc
3481 cagcagtttg ggaggctgag ggggtaggat cacctgaggt caggagttgg agactagcct
3541 ggccaacatg gtgaaactgt ctctactatt agttgggcat ggtggcagat gcctataatc
3601 ctcactattc aggaggctga ggcaggaaaa tcgcttgaat ccaggaggtg gatattgcag
3661 taaagcgaga tttcgccact gcacactagc gtagatgaca gagggagagt gagactctgt
3721 cttaaaagaa aaaaaaaaat cagctgattg tcttataatc cctgcacttt ggaaggccga
3781 ggagggagta tcgcttgagg cgaggagttc aggaccagcc tgggcaacac agcgagaccc
3841 tcatctccac aaaaaatttt aaaaacttac ctgggcatgg tggctcatgc ctgtggtccc
3901 agttatttgg aaggctgagg tgggagaatc acttgagcct gggagttcaa ggctgcagtg
3961 agctatgatc cccctattgc acttcagcct ggatgacaga atgagaccct atctcaacaa
4021 taaaaaaaag ttaggctgat tagcaatcta attcaatctg cacccttgat cctcccttgc
4081 catgtagtat agcatagtca cagttctggg gattaggaca tggacatctt cccactatgg
4141 gggcagccag gagggaccac aggctgaccg ctatctttct gcctgctttc actcatctcc
4201 acacaattcc ttccttcctc tcgctctctt ctttcttttc ttcttttctt ttgtctcttt
4261 ctcttttctt tttttctttc tctttttctt tctttctttc tctttctttt ctttcctttc
4321 ttttcttctt tccctcatct tcacacaatg ctttctccct ttctttcttt ccttctttct
4381 ttctctttct ttctttctct ctctctctct ctctctctct ttctttcttt ctttctttct
4441 ttttctctct ctctctctat ctttcttttt cattttgttg agagacagtc tcactctgtg
4501 gcccaggctg gagtgcagtg atgcaatctc ggctcactac aacctccgcc tcctgagttc
4561 aagtgattct cctgcctcag cctcctgagg cataatgcat cctggaattc ctacatctgt
4621 tcctgcctct gggcatcagt cctcagggat cttggagggg agcagcagga ggagcctgtg
4681 ggttggggtg gtggtgttgg tggcttcaga caaaagcaga cagagaagtg actccggaca
4741 tgcatgctct gtgtagatgt agtggagacc gaggtgggca tggaagtgtc tgtggatcag
4801 cagttctcgc cggacctcaa tgacaacact tcccaggcct acagggattt caacaagacc
4861 ttctggaatc aggtaaaggg caaagagagg ggattttttt tttttttgag gtgtagtctc
4921 gcactctcac cctggctgga gtgcaatggt gcgatcttgg gtcactgcaa cctccgcctc
4981 ccgggttcac atgattctct tgcctcagcc tcccaagtag ctgggattac aggtgcacac
5041 catgacacct ggctaatgtt ttgtattttt agtagagacg ggttttcact atgttggcca
5101 gactggtctc gaactactga ctttgtgatc cacctgcctc gtcctcccaa agtgttggga
5161 ttacaggcgt gagccacggc acccggccgg ggaggggaat tgaagggtct tccctggagc
5221 tggggttggg cgtctgggtc ccctcaggtc tgcaggttcg gacgtgagcc cagggatcct
5281 tggtgtttca gatgcagaag atttttgcag acatgcaggg cttcaccttc aagggtgtgg
5341 agatcctgtc cctgaggtag gagacccatc tggggatgcg gaggcggtgt tgggtggggg
5401 aaatgtgcgc acacaaaaaa cccattcctt tcttttgtaa tcatcagatt ttataaagag
5461 gggtggaggg ggtacataag gaatcactcc ctgggtattt tttcggatcg ttttctgggg
5521 ccatttatct ggaggagggg tggcacctct cttcttcagc acactggaag gagagaagtt
5581 gcagggacat gtgggaaggt ggtgcctgga ttgatgactt tgtccccctc tggctggccc
5641 ctgctctact gagtgggtca gcattagaaa gagagagaga gaaagagaga gagggagaga
5701 acgcacgtct aggggcgccc ggtggatgat ggcttgatgc aacaagaaga gaacgtcagg
5761 ccagatgtgg tggctcacac ttgcnatcct agcactttgg gtaggctagg cgggtggatc
5821 acctgaaagc agttcaagac caacctgggc aacatagtga gaacccatcc ctacaacaat
5881 aaaaatagta ataataataa taataataaa atgattagcc aggcatggta gtgcacacct
5941 gtagtccctg atacttggga ggctgaggag aaaggatcac tttagcccag gagttggagg
6001 ctgcagtgag ctacaatgat accactgcac tccagcctgg gtgacagcaa gactttgtct
6061 ctataaaaca cacagagaga ggaagtcaat catgtcagtc attccttgtc ctgccttccc
6121 aggcagacca agtcaggaat gctggcagcc ccttctgaaa aggatgcacg tggcatccca
6181 actcatgacc tctgctccct tcccccttct ggtgcacttt gggttgcttc tggaggtgcc
6241 cctccaagga cccatatgtt cctggctggg gcactctcta aggctgtgga cccctcagga
6301 atggcagcat cgtggtggac tacctggtcc tgctggagat gcccttcagc ccccagctgg
6361 agagcgagta tgagcaggtg aagaccacgc tgaaggaggg gctgcagaac gccagccagg
6421 atgtgaacag ctgccaggac tcccagagtg agcccaggct ggagggaggg gccagggcct
6481 gaggtgtcac cccagcccac tccagctcag ccagggggcc actgggctca ggtgccagcc
6541 ctgtggtacc tctggcaggt tgggagaagg ggaataagtc cacacacaac ggtgtcaagg
6601 gtggggctag ggagggtctc cccgtgacct cggtactggg aaagagaccc cctgattgtc
6661 atggtcagca tttcccggat ggctgaagac ctcggattat tcaggggaga tgaggcaggc
6721 aacaggagtc ttcgcctgtg gctctctccg tctgggagag ggctctccca gacggagaga
6781 gccctcactg ccctccctgt gcctatcctg cctcctggcg ctaacccctt gaccttaacc
6841 ccttgatctg ccccgcccat tccatctgtg cctgtgtttc cgcagccctg tgttttaagc
6901 ctgactccat caaggtgaac aacaacagca agacagagct gaccccggca ggtaagggtg
6961 gggtaaaggg ctgagtggtc tcccgcggct atgatccggg ctaccaggga catttgccca
7021 ttgaagcctg tgggcaggga gagacctttg ggggaggcaa gtcatgtggc ccaggcggcc
7081 cttcctggcg ctggttagtg gcttccacct gaggacagca ggggccacga ggagagggtg
7141 agggtgctgc gggtggcctc ccctcatcga atcccagggt ctaccccaca gcatcccacc
7201 tcggaaatgg aatcctcctc gcgcatattc agaggcacca ttatcaggcc cctgaataga
7261 atggatgagg ttcttgtctc tgtgcatccc cctccccaac ccccagccat ctgccgccgc
7321 gccgctccca cgggctatga agagttctac ttccccttgg tggaggccac ccggctccgc
7381 tgtgtcacca aatgcacgtc tggggtggac aacgccatcg actgtcacca gggccagtgc
7441 gttctggaga cgagcggtcc cacgtgtcgg taaggccccg ctcaccatcg gcatcagccg
7501 agcccctccc actcattcta ggatgaagcc ctgccccatg ctccgccccg gctccgcgcc
7561 ctgggcctac agtggagcct cgtccccaga gtgccgctcc aagcccatcc ccgttgccct
7621 acagtggagc cctgccctgg agctctgctc ctttgatggg gttgagtcct gtcccctaat
7681 tctgggagag aaccccgccc actcattcta gggtggggcc ccgcctcctc gttctagggt
7741 tgaaccccgc cccctccttc tagggtggag ccctgcccac ttgatctaag gtggaatccc
7801 gccccctcac ctagggtaga gccccggccc ctcgttctag ggtggattcc cagccccttg
7861 tctagggtgg aaccccccgc tgccctaggc tggagccccg ccccctcacc cgcccccgcg
7921 gggcccaggt gcacgggtgg accccgagcc cggaggtgaa gagggtctga ccctgcgatc
7981 tcccgcagct gctactccac cgacacgcac tggttctctg gcccgcgctg cgaggtggcc
8041 gtccactgga gggcgctggt cgggggcctg acggccggcg ccgcgctgct ggtgctgctg
8101 ctgctggcgc tgggcgtccg ggcggtgcgc tccggatggt ggggcggcca gcgccgaggc
8161 cggtgagcgt gcggggggcg gggccggggg gcgagggcag ccaaggggtc ccaggcgggc
8221 cggctctgtc tgaccgcgcg gcggccccac ctaggtcctg ggaccaggac aggaaatggt
8281 tcgagacctg ggatgaggaa gtcgtgggca ctttttcaaa ctggggtttc gaggacgacg
8341 gaacaggtga gtcctgcctc ctggggaagc aggcagaggc tttcctgggc accactgcga
8401 ggacagacgc cctccctgcc ttcctcgcat ttactccgtc cccctctccc ttccgtcccc
8461 tccctctccc cttctctttc tccgctcctc tctctctcta gacaaggata caaatttcta
8521 tgtggccttg gagaacgtgg acaccactat gaaggtgagg ggctaaagag ggggacccca
8581 aggaactctc ccagcctcca ttccagaatc cctccccgac ccccaccagg gcagggaggg
8641 ggctgggctc ggatcagcag tgacctccct gtcagcccaa accagtggct ccgcgttccc
8701 gtccctcact gtgactctga caggtgcaca tcaagagacc cgagatgacc tcgtcctcag
8761 tgtgagccct gcggggcccc ttcaccaccc cctccgccct gccccggaca caagggtctg
8821 cattgcgtcc atttcaagag gtggccccag gacgcgggca gcccaggctc ctgctgttct
8881 tgggcaagat gagactgttc ccccaaatcc catccttctc cttccaactt ggctgaaacc
8941 cacctggaga cgcagttcac gtccaggttc ttccactgtg gaatcttggg caagtcagta
9001 acgagcctca gtttcctcac ctgcaaaacg ggtacagcat tcctgtatga tacgtcacgc
9061 cgttgttgtg aaaaccacat agacttggtc aattctcggt cctactctgc cctcccgtct
9121 cagccctcgt gttgccattg cctctctcgg atcctccaat cctcacgtcc ttcacctggt
9181 ctctggccct ggttcttatt ttctctcaat tccctactgc ctgtttctta ctttgaacct
9241 ggaggcagcc tgcagcccca tcccatctcc tgccctctcc tgatctaact ccctgctgca
9301 tctcttgctc tcattcctta gacgtcctcc ccttttgacc ccgttccttc atccatcctg
9361 caccccagtc ccccagccct aaatcctccc tcctctcctc acatcctggt ccctagcaag
9421 gtatagatag cctctgtgtc ttaggatacc ccgggtgctg ttccctcggt caccctgttg
9481 cccagttccc cgtttctctt gctctcattc cttgtatcct ttcccctttt gagcccgtcc
9541 attcatcggt tctgcccccg actcccccag ccctaaatac cccagctgct gttcccccca
9601 tcaccctgct gcccaattct ttattctcca cccctttctc tcacccctgg agccctgcgg
9661 gtgggggcag ggcatgagtt ccccagtccc caaggaaagg cagccccctc agtctccctc
9721 ctcctcattc ccttccatct ccctcccctc tgccttttaa acccatcccc tccgattccc
9781 ctcctccccc ctctctccct ggtgtcacct ggattcctgc agtaattctg agcccttgaa
9841 atcctcagtc gccttggcgg ggaagattgg ctttggggac aggaagtcgg cacatctcca
9901 ggtcttcatg tgcacaatat agagtttatt gtaaaaagca gcagctctct gtcggtctcc
9961 ttttcacccc ctcagtggtc tctgtttgat cagagaacag ggatttccag aggtggcact
10021 gtaggaggat cctgggagca cctgtgtctc ctggggacaa aggagggggt ctgtgggcag
10081 cccttggggg ccatgaggtt cctcacagaa aacacagagg ttggggggac ccattttatt
10141 ggggagtgac tctgggcagg ggccccttgg gctttgtcat ctatgctctc cccaccccca
10201 ccactgccct gaccttgata ctgggggctt agggagcaat tagacccctg gtgttggttc
10261 agggagttgg gtggtccagg ggctagggct gcctggtcca gccacctttt gcaaggatgg
10321 gtaaagctga gcctccccaa agatcttgat cccccacaag gcccccaaac cctgatagca
10381 aactcacaca gcagagcctg tctatgctgg caccgggccc ttctgttcct gctgttgtgg
10441 gcagtcaggc ctgcctgagg agtcgagagt gatcagaaat aacgtgtccc cttgggtctt
10501 tgggtgctgg cttgggagag gcccctttga tgctttctct gggcagggat gggccatggc
10561 cttttgtcac ctctgtgtct ggccaggggt tgggggacaa ggaccattaa aagtcttaag
10621 gtggtgaagt ggggcccttc tgcccaagga agaagggctt ggaaacttgg gggaccccca
10681 ggggaaaagg cccctnggac attttggg
//