LOCUS AF113615 3775 bp mRNA linear HUM 21-JUN-1999
DEFINITION Homo sapiens FH1/FH2 domain-containing protein FHOS (FHOS) mRNA,
complete cds.
ACCESSION AF113615
VERSION AF113615.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3775)
AUTHORS Westendorf,J.J., Mernaugh,R. and Hiebert,S.W.
TITLE Identification and characterization of a protein containing formin
homology (FH1/FH2) domains
JOURNAL Gene 232 (2), 173-182 (1999)
PUBMED 10352228
REFERENCE 2 (bases 1 to 3775)
AUTHORS Westendorf,J.J., Mernaugh,R. and Hiebert,S.W.
TITLE Direct Submission
JOURNAL Submitted (16-DEC-1998) Biochemistry, Vanderbilt University, 512
MRB-II, 23rd and Pierce, Nashville, TN 37232, USA
FEATURES Location/Qualifiers
source 1..3775
/db_xref="H-InvDB:HIT000069787"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
gene 1..3775
/gene="FHOS"
CDS 19..3513
/gene="FHOS"
/note="128 kDa protein; highly expressed in spleen"
/codon_start=1
/product="FH1/FH2 domain-containing protein FHOS"
/protein_id="AAD39906.1"
/translation="MAGGEDRGDGEPVSVVTVRVQYLEDTDPFACANFPEPRRAPTCS
LDGALPLGAQIPAVHRLLGAPLKLEDCALQVSPSGYYLDTELSLEEQREMLEGFYEEI
SKGRKPTLILRTQLSVRVNAILEKLYSSSGPELRRSLFSLKQIFQEDKDLVPEFVHSE
GLSCLIRVGAAADHNYQSYILRALGQLMLFVDGMLGVVAHSDTIQWLYTLCASLSRLV
VKTALKLLLVFVEYSENNAPLFIRAVNSVATTTGAPPWANLVSILEEKNGADPELLVY
TVTLINKTLAALPDQDSFYDVTDALEQQGMDTLVQRHLGTAGTDVDLRTQLVLYENAL
KLEDGDIEEAPGAGGRRERRKPSSEEGKRSRRSLEGGGCPARAPEPGPTGPASPVGPT
SSTGPALLTGPASSPVGPPSGLQASVNLFPTISVAPSADTSSERSIYKARFLENVAAA
ETEKQVALAQGRAETLAGAMPNEAGGHPDARQLWDSPETAPAARTPQSPAPCVLLRAQ
RSLAPEPKEPLIPASPKAEPIWELPTRAPRLSIGDLDFSDLGEDEDQDMLNVESVEAG
KDIPAPSPPLPLLSGVPPPPPLPPPPPIKGPFPPPPPLPLAAPLPHSVPDSSALPTKR
KTVKLFWRDVKLAGGHGVSASRFGPCATLWASLDPVSVDTARLEHLFESRAKEVLPSK
KAGEGRRTMTTVLDPKRTNAINIGLTTLPPVHVIKAALLNFDEFAVSKDGIEKLLTMM
PTEEERQKIEGAQLANPDIPLGPAENFLMTLASIGGLAARLQLWAFKLDYDSMEREIA
EPLFDLKVGMEQLVQNATFRCILATLLAVGNFLNGSQSSGFELSYLEKVSDVKDTVRR
QSLLHHLCSLVLQTRPESSDLYSEIPALTRCAKVDFEQLTENLGQLERRSRAAEESLR
SLAKHELAPALRARLTHFLDQCARRVAMLRIVHRRVCNRFHAFLLYLGYTPQAAREVR
IMQFCHTLREFALEYRTCRERVLQQQQKQATYRERNKTRGRMITETEKFSGVAGEAPS
NPSVPVAVSSGPGRGDADSHASMKSLLTSRLEDTTHNRRSRGMVQSSSPIMPTVGPST
ASPEEPPGSSLPSDTSDEIMDLLVQSVTKSSPRALAARERKRSRGNRKSLRRTLKSGL
GDDLVQALGLSKGPGLEV"
BASE COUNT 792 a 1175 c 1101 g 707 t
ORIGIN
1 tgagccggcc gcagagccat ggcgggcggg gaagaccgcg gggacggaga gccggtatca
61 gtggtgaccg tgagggtgca gtacctggaa gacaccgacc ccttcgcatg tgccaacttt
121 ccggagccgc gccgggcccc cacctgcagc ctggacgggg cgctgccctt gggcgcgcag
181 atacccgcgg tgcaccgcct gctgggagcg ccgctcaagt tggaggattg tgctctgcaa
241 gtgtctccct ccggatacta cctggacacc gagctgtccc tggaagagca gcgggagatg
301 ctggagggct tctatgaaga gatcagcaaa gggcggaagc ccacgctgat ccttcggacc
361 cagctctctg tgagggtcaa cgctatcttg gaaaagctgt atagctccag tggtcctgag
421 ctccgccgct ccctcttctc actgaagcag atcttccagg aggacaaaga cctggtgcct
481 gaatttgtgc attcagaggg gctgagctgc ctgatccgtg tgggtgctgc tgccgaccac
541 aactaccaga gctacatcct tagagcgctc ggccagctga tgctctttgt ggatggaatg
601 ctgggggtgg tggcccacag tgacactatt cagtggctgt acacattgtg tgccagcctg
661 tcccgcttgg tggtgaagac agccctgaag ctgctgttgg tgtttgtaga atactccgaa
721 aacaacgcac cgctgttcat ccgtgcagtg aactctgtgg ccacgaccac cggtgctcct
781 ccctgggcca atctggtgtc catcctggag gagaagaatg gcgctgaccc tgagttgttg
841 gtgtacacgg tcaccctcat caacaagacg ctggcggcgc tcccggacca ggactccttc
901 tacgatgtga cggatgcact ggagcagcag ggcatggaca cgctggtcca gcgccacctg
961 ggcactgcgg gcactgacgt cgacctgcgc acgcagcttg tgctctacga gaacgccctg
1021 aaattggagg atggagacat cgaagaagcc ccaggcgctg gtgggcggcg ggaacgacga
1081 aagccttctt ctgaggaggg caagaggagc cgccgttctc tggaaggcgg gggctgcccc
1141 gcgcgtgccc cggaacctgg ccccacaggc cccgcctcac cggtaggccc cacctcttcc
1201 accggccccg ccctgctgac aggccccgcc tccagccctg tgggccctcc ctccggtctc
1261 caagcttcag tgaacctttt tcctaccatc tctgtggcac cctcagctga cacctccagc
1321 gagaggagca tctacaaagc ccggttcctg gagaatgtgg cggcagcaga aacagagaag
1381 caggttgcgc tggcccaggg ccgggcagag acacttgccg gggccatgcc caatgaggcg
1441 ggtggacacc cagatgcccg gcaactctgg gactccccag agacagcccc tgcagccaga
1501 acaccccaga gccctgcccc ctgtgtcctg ctccgggccc agcgaagcct tgcaccagag
1561 cccaaggagc cactgatacc agcaagcccc aaggctgagc ccatctggga gctccctacc
1621 cgtgcaccca ggctctctat tggggacctg gacttttcag atctagggga ggatgaagac
1681 caggacatgc tgaatgtaga gtctgtggag gctgggaaag acatcccagc tccctcaccc
1741 ccactgcccc tgctctcggg agtacccccc cctcccccac ttccacctcc cccacccatc
1801 aaaggcccct tcccaccacc tccacctcta cctctggctg cccctcttcc ccattcagtg
1861 cctgacagct cagccctccc cactaagagg aagacagtaa aacttttctg gcgtgacgtg
1921 aagctggctg ggggccatgg agtctctgca agccgctttg ggccctgcgc caccctctgg
1981 gcttcactgg accctgtctc agtggacacg gcccgactgg aacacctctt tgagtctcgt
2041 gccaaagagg tgctgccctc caagaaagct ggagagggcc gccggacaat gaccacagtg
2101 ctggacccca agcgcacgaa cgccatcaac atcggcctaa ccacactgcc acctgtgcat
2161 gtcattaagg ctgctctgct caactttgat gagtttgctg tcagcaagga tggcattgag
2221 aagctactga ccatgatgcc cacggaggaa gagcggcaga agattgaggg agcccagctg
2281 gccaaccctg acatacccct gggcccagcc gagaacttcc tgatgactct tgcctccatt
2341 ggcggcctcg ctgctcgtct acaactctgg gccttcaagc tggactatga cagcatggag
2401 cgggaaattg ctgagccact gtttgacctg aaagtgggta tggaacagct ggtacagaat
2461 gccaccttcc gctgcatcct ggctaccctc ctagctgtgg gcaacttcct caatggctcc
2521 cagagcagcg gctttgagct gagctacctg gagaaggtgt cagatgtgaa ggacacggtg
2581 cgtcgacagt cactgctaca ccatctctgc tccctagtgc tccagacccg gcctgagtcc
2641 tctgacctct attcagaaat ccctgccctg acccgctgtg ccaaggtgga ctttgaacag
2701 ctgactgaga acctggggca gctggagcgc cggagccggg cagccgagga aagcctgcgg
2761 agcttggcca agcatgagct ggccccagcc ctgcgtgccc gcctcaccca cttcctggac
2821 cagtgtgccc gccgtgttgc catgctaagg atagtgcacc gccgtgtctg caataggttc
2881 catgccttcc tgctctacct gggctacacc ccgcaggcgg cccgtgaagt gcgcatcatg
2941 cagttctgcc acacgctgcg ggaatttgcg cttgagtatc ggacttgccg ggaacgagtg
3001 ctacagcagc agcagaagca ggccacatac cgtgagcgca acaagacccg gggacgcatg
3061 atcaccgaga cagagaagtt ctcaggtgtg gctggggaag cccccagcaa cccctctgtc
3121 ccagtagcag tgagcagcgg gccaggccgg ggagatgctg acagtcatgc tagtatgaag
3181 agtctgctga ccagcaggct tgaggacacc acacacaatc gccgcagcag aggcatggtc
3241 cagagcagct ccccaatcat gcccacagtg gggccctcca ctgcatcccc agaagaaccc
3301 ccaggctcca gtttacccag tgatacatca gatgagatca tggaccttct ggtgcagtca
3361 gtgaccaaga gcagtcctcg tgccttagct gctagggaac gcaagcgttc ccgcggcaac
3421 cgcaagtctt tgagaaggac gttgaagagt gggctcggag atgacctggt gcaggcactg
3481 ggactaagca agggtcctgg cctggaggtg tgaaggtgct gtatcccgga aatctatctg
3541 gaccctggac tgcagtgcag gagatgacag agtgaggagg gcccagagca gaattctggc
3601 cccagaactc tgtgcccagg agccatgcct tgagcagtat tagccgtgtg tgtatgcatg
3661 tgagtgtgtg tgtatgtgtg tgtgtgcatg catatgcatg tgcatgtgtg tgagctcctt
3721 gaacgcacgg agcaaaataa aattttctta gctaatccca aaaaaaaaaa aaaaa
//