LOCUS AF113141 5900 bp DNA linear HUM 25-MAR-1999
DEFINITION Homo sapiens serine protease prostase gene, complete cds.
ACCESSION AF113141
VERSION AF113141.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5900)
AUTHORS Nelson,P.S., Gan,L., Ferguson,C., Moss,P., Gelinas,R., Hood,L. and
Wang,K.
TITLE Molecular cloning and characterization of prostase, an
androgen-regulated serine protease with prostate-restricted
expression
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 96 (6), 3114-3119 (1999)
PUBMED 10077646
REFERENCE 2 (bases 1 to 5900)
AUTHORS Nelson,P.S., Gan,L., Ferguson,C., Moss,P., Gelinas,R., Hood,L. and
Wang,K.
TITLE Direct Submission
JOURNAL Submitted (10-DEC-1998) Chiroscience R & D, 1631 220th St SE,
Bothell, WA 98021, USA
FEATURES Location/Qualifiers
source 1..5900
/organism="Homo sapiens"
/mol_type="genomic DNA"
/db_xref="taxon:9606"
/chromosome="19"
/map="19q13"
mRNA join(<1411..1471,2735..2897,3319..3569,3653..3789,
5062..5817)
/product="serine protease prostase"
CDS join(1411..1471,2735..2897,3319..3569,3653..3789,
5062..5214)
/note="androgen regulated"
/codon_start=1
/product="serine protease prostase"
/protein_id="AAD21581.1"
/translation="MATAGNPWGWFLGYLILGVAGSLVSGSCSQIINGEDCSPHSQPW
QAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQEPGSQMVEASLS
VRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPTAGNSCLVSGWGLLANGR
MPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQKDSCNGDSGGPLICNGYLQ
GLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS"
exon 1411..1471
/number=1
exon 2735..2897
/number=2
exon 3319..3569
/number=3
exon 3653..3789
/number=4
exon 5062..5817
/number=5
BASE COUNT 1417 a 1643 c 1569 g 1271 t
ORIGIN
1 acctgccgca gagctcggag tgtggtaggc actcagctgc ttttcactga gcgaagactt
61 tttagttctc ccgctcaccg agagcctaca atgtgcctgg cactgtgtgc ctttccctga
121 attacctctt tgaatccact tgggaaatgg ggcataatgg tcactccagt tttacagttg
181 gaaaaacagg ctcacagggg tgcagtcact tgcccaaggt tccaaaaata gttcgtgatg
241 taggctggat acgaacctgg ggaaatttgc tggagaagca cagaaagaga gggatgaagg
301 aggaggggag agagagagag agatttaatt taaaaagaga aagaacatga gagagaacag
361 gagagaatga gaggaaatga aagaaaacac gagaaaaata atgagagaga gaatgagaga
421 aagaaagaag aagagaaaga gaaaatgaga gatacaggca agagagaggt atctcatgag
481 agagaataag aacatgaaaa gagaaagaat gagagagaga gagagaaaga aaaaggagag
541 tggagtctag gatctgggca ggggtctcct ccctgggtcc ctagaccctg ctgccagccc
601 cttctgggcc cccaaccact gcctggtcag agttgaggca gcctgagaga gttgagctgg
661 aagtttgcag cacctgaccc ctggaacaca tcccctgggg gcaggccagc ccaggctgag
721 gatgcttata agccccaagg aggcccctgc gggaggcagc aggctggagc tcagcccagc
781 agtggaatcc aggagcccag aggtggccgg gtaagaggcc tggtggtccc ccactaaaag
841 cctgcagtgt tcatgatcca actctcccta cagctccatg tcgctggatt ctcagcctct
901 gtgccttctg tctccacatc tctctagaca gatctctcac tgtctctagt taggagtcac
961 tgtctctagt taggggtctc tctgtctctc tgaatctata tctccatgtc taactctcag
1021 actgtctctg aggatatctc tcaagcactc tgtctctccg gctctgattc tctgtgtgtc
1081 ttccctccat gcttgtttgt gggtggctag acaccatctc tccccattca cagatggcta
1141 gatgctttct ctaaactttc ctttctacct agttctctct ctctctctct tttcccatct
1201 ctctctctct ttttctctct cagtctctaa atctgtctct ctaggttctg ggtccatgga
1261 tgggagaggg ggtagatggt ctaggctctt gcctacctaa taacgtccca gagggaagaa
1321 agggagggac aaagagaggg atggagagac ttgggctgaa gatccccaga cacggctaag
1381 tctcagtcct catccccagg tgctgacgtg atggccacag caggaaatcc ctggggctgg
1441 ttcctggggt acctcatcct tggtgtcgca ggtatctgag tatgcgtgtg tgtgtctgtc
1501 cgtgcttggg ggcacagtgt ttgttaatgt tcaggtgtga ctcagtgtcc tcttgcttgt
1561 gactgcaaag ctgcctgtga gacggtaccg tgttatccgt cccccatggc tgtgcccctg
1621 caactccttg tatcgtggta aatttgtgtg tggcagtgtg cctgggtgtg tggttgtacc
1681 tgtgagactc tgacagtttg tgcctctgaa tatctggtgg agtgacaaca gtgtaatgat
1741 gatatgggga caggggaagc cgagggtgca ggagattgtg cttcctgggg cgtgatccat
1801 tgctgggaat ctgtgcctgc ttcctgggtc ttcagtcctg agatccccct ctcccatccc
1861 caaggaactc acctcacagg actataaaac ggtgttttgg tgtgcatggg cttgtggctt
1921 ggtgtgactg tgggcaaggc tgggagagga taggagtgac tcggcgcagg accgactctt
1981 tgagcatcag tctgcgcaga caagtgaccc gatccttgct cccagcaaca actccacccc
2041 ctgagcttta attcaccccg aaggacccga tcctactgct atgagcctag actcctctgt
2101 tgaacccctc ctgaccgtgg ctttgcaccg cgatggcacc agtctcacct ccagagctca
2161 ccccagagcc ctgactccgc cccagaagcc ctggtcccac cttctgagac tgcctctagc
2221 cataacccag ctcttgaagc cttgatggcg cccctgcgct gtaaccccaa ccctaggagc
2281 actgatcccg ccttctcagc ccacccccat gccctgactc tcctcccagg agccctgact
2341 accctgaatc cctgaccagg ctcctgcacc gtgatcaccg cccctgggag ccctaggcct
2401 atatcctgga ccagcccctg aagctccgat catgacccct gcaccataac cccaccccca
2461 ggagccctgg gtccgccccc tgggcccgcc cccagccctg actcggcccc ccaagagtcc
2521 tgactgctcc tgaagccctg accacgcccc tgctcggtaa cccctccccc aagagccctg
2581 ggcccgcctc ctgagcccgt tcccagccct gactccgccc cgaggagccc tgactgctcc
2641 tgaacctctg accacgcccc tgctcggtaa gcccaccccc aggaaccctg ggcccgcctc
2701 ctggtcccga tcccatccct gactccgccc tcaggatcgc tcgtctctgg tagctgcagc
2761 caaatcataa acggcgagga ctgcagcccg cactcgcagc cctggcaggc ggcactggtc
2821 atggaaaacg aattgttctg ctcgggcgtc ctggtgcatc cgcagtgggt gctgtcagcc
2881 gcacactgtt tccagaagtg agtgcagagg tagggggagt gggcagggcc tgggtccggg
2941 ggcggggcct aatatcaggc tcatcttggg gtgctcaggg ggaaacagcg gtgaaggctc
3001 tgggaggagg acggaatgag cctggatccg gggagcccag agggaagggc tgggaggcgg
3061 gaatcttgct tcggaaggac tcagagagtc ctgacttgaa atctcagccc agtgctgagt
3121 ctctagtgaa ctaaggcaag ttcttgtccc tgaatttttg tgaatgagga tttgagacca
3181 tggttaagta gctcttaggg tgtttagcga agagggtggg gttggggtta ggagatgggg
3241 atgggaatgg ggttgaagat gagaatggag gtaaggatgt agttgccaca aaactgacct
3301 gccctccgtg gcccacagct cctacaccat cgggctgggc ctgcacagtc ttgaggccga
3361 ccaagagcca gggagccaga tggtggaggc cagcctctcc gtacggcacc cagagtacaa
3421 cagacccttg ctcgctaacg acctcatgct catcaagttg gacgaatccg tgtccgagtc
3481 tgacaccatc cggagcatca gcattgcttc gcagtgccct accgcgggga actcttgcct
3541 cgtttctggc tggggtctgc tggcgaacgg tgagctcacg ggtgtgtgtc tgccctcttc
3601 aaggaggtcc tctgcccagt cgcgggggct gacccagagc tctgcgtccc aggcagaatg
3661 cctaccgtgc tgcagtgcgt gaacgtgtcg gtggtgtctg aggaggtctg cagtaagctc
3721 tatgacccgc tgtaccaccc cagcatgttc tgcgccggcg gagggcacga ccagaaggac
3781 tcctgcaacg tgagagaggg gaaaggggag ggcaggcgac tcagggaagg gtggagaagg
3841 gggagacaga gacacacagg gccgcatggc gagatgcaga gatggagaga cacacaggga
3901 gacagtgaca actagagaga gaaactgaga gaaacagaga aataaacaca ggaataaaga
3961 gaagcaaagg aagagagaaa cagaaacaga catggggagg cagaaacaca cacacataga
4021 aatgcagttg accttccaac agcatggggc ctgagggcgg tgacctccac ccaacagaaa
4081 atcctcttat aacttttgac tccccaaaaa cctgactaga aatagcctac tgttgacggg
4141 gagccttacc aataacataa atagtcgatt tatgcatacg ttttatgcat tcatgatata
4201 cctttgttgg aattttttga tatttctaag ctacacagtt cgtctgtgaa tttttttaaa
4261 ttgttgcaac tctcctaaaa tttttctaat gtgtttattg aaaaaatcca agtataagtg
4321 gacttgtgca gttcaaacca gggttgttca agggtcaact gtgtacccag agggaaacag
4381 tgacacagat tcatagaggt gaaacacgaa gagaaacagg aaaaatcaag actctacaaa
4441 gaggctgggc agggtggctc atgcctgtaa tcccagcact ttgggaggcg aggcaggcag
4501 atcacttgag gtaaggagtt caagaccagc ctggccaaaa tggtgaaatc ctgtctgtac
4561 taaaaataca aaagttagct ggatatggtg gcaggcgcct gtaatcccag ctacttggga
4621 ggctgaggca gaagaattgc ttgaatatgg gaggcagagg ttgaagtgag ttgagatcac
4681 accactatac tccagctggg gcaacagagt aagactctgt ctcaaaaaaa aaaaaaaaaa
4741 aaagacttta caaagagatg cagagacact gagacagata aacaagccac aaaggagaca
4801 aaggagagac agacaaacag aaacagacag accacaagcc caagagaagc agccagcatt
4861 caggacatag gacatcggga agcaggatta gatgaagtca gggatctgga atgggacttc
4921 caacagatat gttgctgggc tatgttgtta ttgatgatgg ttctgtcttt gtttctcagt
4981 ctcatttagt tcctttctga gcccacatcc atttccacct ctctgtgttt tgaattctga
5041 ctctccctct cttcacaaca gggtgactct ggggggcccc tgatctgcaa cgggtacttg
5101 cagggccttg tgtctttcgg aaaagccccg tgtggccaag ttggcgtgcc aggtgtctac
5161 accaacctct gcaaattcac tgagtggata gagaaaaccg tccaggccag ttaactctgg
5221 ggactgggaa cccatgaaat tgacccccaa atacatcctg cggaaggaat tcaggaatat
5281 ctgttcccag cccctcctcc ctcaggccca ggagtccagg cccccagccc ctcctccctc
5341 aaaccaaggg tacagatccc cagcccctcc tccctcagac ccaggagtcc agacccccca
5401 gcccctcctc cctcagaccc aggagtccag cccctcctcc ctcagaccca ggagtccaga
5461 ccccccagcc cctcctccct cagacccagg agtccagccc ctcctccctc agacccagga
5521 gtccagaccc cccagcccct cctccctcag acccaggggt ccaggccccc aacccctcct
5581 ccctcagact cagaggtcca ggcccccaac ccctccttcc ccagacccag aggtccaggt
5641 cccagcccct cctccctcag acccagcggt ccaatgccac ctagactctc cctgtacaca
5701 gtgccccctt gtggcacgtt gacccaacct taccagttgg tttttcattt tttgtccctt
5761 tcccctagat ccagaaataa atcccctaga tccagaaata aagtctaaga gaagcgcagg
5821 ttctgtttgt agtgtcctcc ttgcttcccc ttccattcaa gagattccag caaatggctt
5881 tccctccatg ggtcgcattt
//