LOCUS AF110315 2290 bp mRNA linear HUM 12-MAY-1999
DEFINITION Homo sapiens (HERV-H-HHLA1 fusion) mRNA, complete cds.
ACCESSION AF110315
VERSION AF110315.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2290)
AUTHORS Feuchter-Murthy,A.E., Freeman,J.D. and Mager,D.L.
TITLE Splicing of a human endogenous retrovirus to a novel phospholipase
A2 related gene
JOURNAL Nucleic Acids Res. 21 (1), 135-143 (1993)
PUBMED 8382789
REFERENCE 2 (bases 1 to 2290)
AUTHORS Kowalski,P.E., Freeman,J.D. and Mager,D.L.
TITLE Intergenic splicing between a HERV-H endogenous retrovirus and two
adjacent human genes
JOURNAL Genomics 57 (3), 371-379 (1999)
PUBMED 10329003
REFERENCE 3 (bases 1 to 2290)
AUTHORS Kowalski,P.E., Murthy,A.E., Freeman,J.D. and Mager,D.L.
TITLE Direct Submission
JOURNAL Submitted (01-DEC-1998) Terry Fox Laboratory, 601 W. 10th Ave.,
Vancouver, BC V5Z 1L3, Canada
FEATURES Location/Qualifiers
source 1..2290
/db_xref="H-InvDB:HIT000069635"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="8"
/map="8q24.1-q24.3"
/clone="AF8"
/tissue_type="teratocarcinoma"
/tissue_lib="NTera2D1"
gene 1..2290
/gene="HERV-H-HHLA1 fusion"
/note="fusion transcript generated by transcriptional
read-through from the HERV-H 3' LTR, across a small
intron, and into the HHLA1 reading frame"
misc_feature 1..423
/gene="HERV-H-HHLA1 fusion"
/note="HERV-H sequence"
misc_feature 424..876
/gene="HERV-H-HHLA1 fusion"
/note="HERV-H 3' LTR"
misc_feature 877..1145
/gene="HERV-H-HHLA1 fusion"
/note="intronic sequence"
CDS 899..2065
/gene="HERV-H-HHLA1 fusion"
/note="protein derived from intronic sequence upstream of
the HHLA1 reading frame and the HHLA1 reading frame"
/codon_start=1
/product="unknown"
/protein_id="AAD13107.1"
/translation="MEETNSSSKDMYQSPGEAEGWRWKKGSDRGQNLFRKHSKCLILL
IRERFESPHSYICSPVTFQFFYAQSVKHVNVTIDCLPEGAATRGTARTSKPTTKSQKT
LPSTSPGHWTQSTPWASALRSSPWTETAAPSETEETLNTGRPPELPARATATWFSASH
TLPALATRRVARTQWLTADRQTWASISSVPWAQTISEKKPGGSLWETRSSPPTTAGTE
EAMNTTSLLAPAAEIMATPGSPSQASPTSGAFTHGTQTPSPTKATAPRYPQTGDLSAE
WPFTAGEEPVLVPRPHQVSRCPQPLFKVGAMAAAPLTLAIQRLNPCLMELCQFFQQCL
CMSQRSPRTEDMRYCLEYYSWFLKNATYICQRVKRVSHSHTLKQKCLENICKSV"
misc_feature 1146..2290
/gene="HERV-H-HHLA1 fusion"
/note="HHLA1; Human HERV-H Associated Gene 1"
BASE COUNT 614 a 664 c 450 g 562 t
ORIGIN
1 gaattccctc ttaactcttg aagtaaataa ataatctttg ctggcaggac tatgctgaat
61 ctccttaggc actctctaat tagatgtcct aggtcctccc aattcttagt ccttttatac
121 ctgtttttct ccttctctta ttccatttag tttttcaatt catacaaaac tgtatccagg
181 ccatcaccta tcattctata caacaaatgt ttcttctaac atccccacaa tatcacccct
241 taccacaaga cctcccttca gcttaatctc tcccactcta ggttcccacg ctgcccctaa
301 tcccgcttga agcagccctg agaaacatcg cccattctct ctccatacca ccccccaaaa
361 attttcgcca ccccaacact tcaacactat tttatttttc ttattaatat aagaaggcag
421 gcatgtcagg cctctgagcc caagccaagc catcgcaacc cctgtgactt gcacctatac
481 gcccagatgg cctgaagtaa ctgaagaatc acaaaagaag tgaatatgcc ttgccccacc
541 ttaactgatg acattccacc acaaaagaag tgtaaatggc cggtccttgc cttaactgat
601 gacattacct tgtgaaagtc ctcttcctgg ctcatcctgg ctcaaaaagc acccccactg
661 agcaccttga gacccccact cctgcccgcc agagaacaaa ccccctttga ctgtaatttt
721 cctttaccta cccaaatcct ataaaacggc cccaccctta tctcccttca ctgactctct
781 tttcggactc agcccgcctg cacccaggtg aaataaacag ctttattgct cacacaaagc
841 ctgtttggtg gtctcttcac acggacgcac atgaaattta gttgtatcca taaggcatat
901 ggaggagact aattcctctt ccaaagacat gtaccagagt cctggagagg ctgagggctg
961 gaggtggaag aaaggctctg acaggggtca gaatctgttc aggaaacata gcaaatgcct
1021 gatactttta attagagaaa ggtttgaatc tccacattca tatatttgca gtccagtgac
1081 ctttcagttt ttttatgccc aaagtgtcaa gcatgttaat gttaccattg actgcctccc
1141 tgaaggtgca gctaccaggg gaactgccag gacttcaaag cccacaacca aaagccagaa
1201 aacactacca agtacaagcc ccggacactg gacccagagc acaccctggg catctgctct
1261 gagatcctct ccctggacag agacagctgc tccttcagaa acagaggaga ccctgaacac
1321 aggcaggcct cctgagcttc cagccagggc cacagccaca tggttcagtg cctcccacac
1381 tctcccagcc ttggctacca ggagggtggc cagaactcag tggttgacag ctgacagaca
1441 gacgtgggct tccatatcgt ccgtgccctg ggctcagacc atcagtgaga aaaaacctgg
1501 agggtctctc tgggaaactc gttcttcccc accgactact gcagggaccg aggaagccat
1561 gaacactaca agccttttgg cgcctgctgc tgagataatg gccacacctg gcagcccatc
1621 ccaggccagc cctacctcgg gagcattcac ccatggcaca cagactccga gtccaaccaa
1681 ggcaacagcc cccagatatc cacaaacagg tgatctctct gcagagtggc cattcactgc
1741 tggtgaagag ccagtcctgg tcccaagacc ccatcaagtt tcaaggtgtc ctcagccact
1801 cttcaaggtg ggagctatgg cagctgctcc tctcaccctg gctattcaga ggctcaaccc
1861 atgcctgatg gagctgtgcc aattcttcca gcaatgcctc tgcatgagcc agaggagtcc
1921 caggacagag gacatgagat actgtcttga atactattcc tggtttctga agaatgcaac
1981 atatatctgt cagagggtga aaagggtgtc ccactcgcac accttaaagc aaaagtgcct
2041 tgagaatatc tgcaagtctg tgtgaggcct tgaaaataac actagggcat aacaattact
2101 tcaggggata cgccatccac cctggctctt gtcccaagtg ggctacattt gaagaattca
2161 cccaggctcc agctagatca tcagttaatt taaagtggtt attcttggaa gtagcatttt
2221 ttttccctct cctgtgaatc tgtgcaaaac attgaaggta gaagttttct tgttaaaaaa
2281 aaaggaattc
//