LOCUS AF109387 1389 bp mRNA linear HUM 21-JUL-2008
DEFINITION Homo sapiens P2X2A receptor mRNA, complete cds.
ACCESSION AF109387
VERSION AF109387.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1389)
AUTHORS Roberts,J.A., Digby,H.R., Kara,M., El Ajouz,S., Sutcliffe,M.J. and
Evans,R.J.
TITLE Cysteine substitution mutagenesis and the effects of
methanethiosulfonate reagents at P2X2 and P2X4 receptors support a
core common mode of ATP action at P2X receptors
JOURNAL J. Biol. Chem. 283 (29), 20126-20136 (2008)
PUBMED 18487206
REFERENCE 2 (bases 1 to 1389)
AUTHORS McMahon,R.A., Egan,T.M., Hurley,P.T., Nelson,A., Rogers,M. and
Martin,F.
TITLE Cloning of the human P2X2 receptor cDNA and multiple splice
variants
JOURNAL Unpublished
REFERENCE 3 (bases 1 to 1389)
AUTHORS McMahon,R.A., Hurley,P.T., Nelson,A., Rogers,M. and Martin,F.
TITLE Direct Submission
JOURNAL Submitted (25-NOV-1998) Biotechnology Centre, University College
Dublin, Belfield, Dublin 4, Ireland
FEATURES Location/Qualifiers
source 1..1389
/db_xref="H-InvDB:HIT000069607"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/tissue_type="placenta"
CDS 1..1380
/note="P2X ligand-gated ion channel"
/codon_start=1
/product="P2X2A receptor"
/protein_id="AAD42947.1"
/translation="MVRRLARGCWSALWDYETPKVIVVRNRRLGVLYRAVQLLILLYF
VWYVFIVQKSYQESETGPESSIITKVKGITTSEHKVWDVEEYVKPPEGGSVFSIITRV
EATHSQTQGTCPESIRVHNATCLSDADCVAGELDMLGNGLRTGRCVPYYQGPSKTCEV
FGWCPVEDGASVSQFLGTMAPNFTILIKNSIHYPKFHFSKGNIADRTDGYLKRCTFHE
ASDLYCPIFKLGFIVEKAGESFTELAHKGGVIGVIINWDCDLDLPASECNPKYSFRRL
DPKHVPASSGYNFRFAKYYKINGTTTRTLIKAYGIRIDVIVHGQAGKFSLIPTIINLA
TALTSVGVGSFLCDWILLTFMNKNKVYSHKKFDKVCTPSHPSGSWPVTLARVLGQAPP
EPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPCPISAPSEQMVDTPASEPAQASTP
TDPKGLAQL"
BASE COUNT 290 a 460 c 383 g 256 t
ORIGIN
1 atggtccggc gcctggcccg gggctgctgg tccgccctct gggactacga gacgcccaag
61 gtgatcgtgg tgaggaaccg gcgcctgggg gtcctgtacc gcgccgtgca gctgctcatc
121 ctgctctact tcgtgtggta cgtattcatc gtgcagaaaa gctaccagga gagcgagacg
181 ggccccgaga gctccatcat caccaaggtc aaggggatca ccacgtccga gcacaaagtg
241 tgggacgtgg aggagtacgt gaagcccccc gaggggggca gcgtgttcag catcatcacc
301 agggtcgagg ccacccactc ccagacccag ggaacctgcc ccgagagcat aagggtccac
361 aacgccacct gcctctccga cgccgactgc gtggctgggg agctggacat gctgggaaac
421 ggcctgagga ccgggcgctg tgtgccctat taccaggggc cctccaagac ctgcgaggtg
481 ttcggctggt gcccggtgga agatggggcc tctgtcagcc aatttctggg tacgatggcc
541 ccaaatttca ccatcctcat caagaacagc atccactacc ccaaattcca cttctccaag
601 ggcaacatcg ccgaccgcac agacgggtac ctgaagcgct gcacgttcca cgaggcctcc
661 gacctctact gccccatctt caagctgggc tttatcgtgg agaaggctgg ggagagcttc
721 acagagctcg cacacaaggg tggtgtcatc ggggtcatta tcaactggga ctgtgacctg
781 gacctgcctg catcggagtg caaccccaag tactccttcc ggaggcttga ccccaagcac
841 gtgcctgcct cgtcaggcta caacttcagg tttgccaaat actacaagat caatggcacc
901 accacccgca cgctcatcaa ggcctacggg atccgcattg acgtcattgt gcatggacag
961 gccgggaagt tcagcctgat tcccaccatt attaatctgg ccacagctct gacttccgtc
1021 ggggtgggct ccttcctgtg cgactggatc ttgctaacat tcatgaacaa aaacaaggtc
1081 tacagccata agaaatttga caaggtgtgt acgccgagcc acccctcagg tagctggcct
1141 gtgacccttg cccgtgtatt gggccaggcc cctcccgaac ccggccaccg ctccgaggac
1201 cagcacccca gccctccatc aggccaggag ggccaacaag gggcagaatg tggcccagcc
1261 ttcccgcccc tgcggccttg ccccatctct gccccttctg agcagatggt ggacactcct
1321 gcctccgagc ctgcccaagc ctccacaccc acagacccca aaggtttggc tcaactctga
1381 gctccttaa
//