LOCUS AF108765 2436 bp mRNA linear HUM 26-JAN-1999
DEFINITION Homo sapiens testis 6-phosphofructo-2-kinase/fructose
2,6-bisphosphatase (PFKFB4) mRNA, complete cds.
ACCESSION AF108765
VERSION AF108765.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2436)
AUTHORS Manzano,A., Perez,J.X., Nadal,M., Estivill,X., Lange,A. and
Bartrons,R.
TITLE Cloning, expression and chromosomal localization of a human testis
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase gene
JOURNAL Gene 229 (1-2), 83-89 (1999)
PUBMED 10095107
REFERENCE 2 (bases 1 to 2436)
AUTHORS Manzano,A., Perez,J.X., Nadal,M., Estivill,X., Lange,A.J. and
Bartrons,R.
TITLE Direct Submission
JOURNAL Submitted (23-NOV-1998) Biochemistry, University of Barcelona,
C/Feixa Llarga s/n, L'Hospitalet, BCN 08907, Spain
FEATURES Location/Qualifiers
source 1..2436
/db_xref="H-InvDB:HIT000069589"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="3"
/map="3p21-p22"
/tissue_type="testis"
gene 1..2436
/gene="PFKFB4"
CDS 23..1432
/gene="PFKFB4"
/note="PFK-2/FBPase-2"
/codon_start=1
/product="testis 6-phosphofructo-2-kinase/fructose
2,6-bisphosphatase"
/protein_id="AAD09427.1"
/translation="MASPRELTQNPLKKIWMPYSNGRPALHACQRGVCMTNCPTLIVM
VGLPARGKTYISKKLTRYLNWIGVPTREFNVGQYRRDVVKTYKSFEFFLPDNEEGLKI
RKQCALAALRDVRRFLSEEGGHVAVFDATNTTRERRATIFNFGEQNGYKTFFVESICV
DPEVIAANIVQVKLGSPDYVNRDSDEATEDFMRRIECYENSYESLDEDLDRDLSYIKI
MDVGQSYVVNRVADHIQSRIVYYLMNIHVTPRSIYLCRHGESELNLKGRIGGDPGLSP
RGREFAKSLAQFISDQNIKDLKVWTSQMKRTIQTAEALGVPYEQWKVLNEIDAGVCEE
MTYEEIQDNYPLEFALRDQDKYRYRYPKGESYEDLVQRLEPVIMELERQENVLVICHQ
AVMRCLLAYFLDKAAEQLPYLKCPLHTVLKLTPVAYGCKVESIFLNVAAVNTHRDRPQ
NVDISRPPEEALVTVPAHQ"
BASE COUNT 549 a 692 c 685 g 510 t
ORIGIN
1 tccgactcat cccggccccg ggatggcgtc cccacgggaa ttgacacaga accccctgaa
61 gaagatctgg atgccataca gcaatgggcg gcccgctctg cacgcttgcc agcgcggtgt
121 gtgcatgacc aactgcccaa ctctcattgt catggtgggc ctgcccgcca ggggcaagac
181 ctacatctcc aagaagctga ctcgatacct gaactggatt ggtgtgccca ctcgggagtt
241 caatgttggc cagtatcgcc gggacgtggt caagacctac aaatcttttg aattttttct
301 ccccgacaat gaagagggcc tgaaaatcag gaagcagtgt gccctggcag ccctccgtga
361 cgtccggcgg ttccttagtg aggagggggg acatgtggcg gtttttgatg ccacaaacac
421 cacccgagaa cggagagcga ccatctttaa ttttggagaa cagaatggct acaagacctt
481 ttttgtcgag tccatctgtg tggatcctga ggtcatagct gccaacatcg tgcaagtgaa
541 actgggcagc cctgactatg tcaaccgcga cagtgatgag gctacggagg acttcatgag
601 gcgcattgag tgctatgaga actcctacga gtcgctagat gaggacctgg atagggacct
661 gtcctatatc aagatcatgg atgtgggcca gagctacgtg gtgaaccgtg tggctgacca
721 catccagagc cgcatcgtat attacctcat gaacatccac gtgacccccc gctccatcta
781 cctctgccgg cacggggaga gcgagctcaa cctcaagggc cggattggcg gggacccagg
841 actgtcccct cggggcaggg agtttgccaa gagtctagcc cagttcatca gtgaccaaaa
901 tatcaaggat ctgaaggtct ggacaagcca gatgaagagg acaatccaga cggctgaggc
961 actgggtgtg ccctatgaac agtggaaggt cctcaacgag atcgatgcgg gcgtctgtga
1021 ggaaatgacc tacgaggaaa ttcaggataa ttatccactg gagttcgccc tgcgggacca
1081 ggacaagtac cggtaccggt accctaaagg ggagtcctac gaggacctgg tccagagact
1141 ggagcctgtc atcatggagc tggagaggca agagaatgtg ctggtcatct gccaccaggc
1201 tgtgatgcgc tgcctgctgg cctacttcct cgacaaggca gcagaacagc tgccctacct
1261 caagtgtccg ctgcacacag tcctgaagct gactcctgtg gcatatggtt gtaaagtgga
1321 gtccatattc ctgaacgtgg ctgctgtgaa cacgcaccgg gacaggcctc agaacgtgga
1381 catctcaaga cctccagagg aagcccttgt cacggtgcct gctcaccagt gaccatgttc
1441 atccactgtg accactaggc aggcactgct ctctgcagag ggggtcattc caggccctcc
1501 agtgtgtgtg atagtcacca tgccatgcag ggatattctt gaagccacac atggctggcg
1561 gaacccagag cccccacccc agcccacctg gctctttgtt gacagtcggc gacaaggttg
1621 tgcgtggctc ctgacctgct gctaagagtc acttgaccag actgcatctg catgggctgc
1681 gcggaggttg cccagcccca gtttcttccg gcgcagctct taggtgttca ctctcgccag
1741 ctcagttggc tttgtgaagt gtgaaaccct acaatgtgaa aggaaagtgc ttgctgtgat
1801 gttcctactg tggcccagct gcccagcatg gacctggtga ctctccacag ggcctctacc
1861 atcctctctg tggccacttc ctgagccaga ggccaggtct tcatggggcc ctgagcttct
1921 gctgcctctg gtgagaggga gagcccttcc catccttacc caccaggaac tagagcccca
1981 accacagcag atgcttcctg ggcagccact ggccaggccg ttgtatccat gtcaccctta
2041 gttgtgggca ttcatgaaag caatgcgctt gcttcagcac attggatgca cagaaacgtg
2101 agggcagggg gcagttgtgg tcgcccctcc ccagttgtgc atgtacccgg ctacttaggt
2161 atgcttaggg gagctggtgg ccaggggtgc cccttcaggc ctgctctcac agtgaaacca
2221 cttcaagaca gggcaggaag ttaccttccc tggtgcacac accgaagtgc tcgagggaga
2281 gctgccgccc cctctcccct tccctggctg tggacactgg cagccaatgg ggaggcggcc
2341 tctcccctgt tgctgcccgt gtccacacag gaatgtacac tggtggcaga aacatgcatt
2401 tgccataaat aattcagaaa caaaaaaaaa aaaaaa
//