LOCUS AF108461 6334 bp mRNA linear HUM 13-APR-2000
DEFINITION Homo sapiens ubinuclein (UBN1) mRNA, alternatively spliced,
complete cds.
ACCESSION AF108461
VERSION AF108461.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 6334)
AUTHORS Aho,S., Buisson,M., Pajunen,T., Ryoo,Y.W., Giot,J.F., Gruffat,H.,
Sergeant,A. and Uitto,J.
TITLE Ubinuclein, a novel nuclear protein interacting with cellular and
viral transcription factors
JOURNAL J. Cell Biol. 148 (6), 1165-1176 (2000)
PUBMED 10725330
REFERENCE 2 (bases 1 to 6334)
AUTHORS Aho,S.
TITLE Direct Submission
JOURNAL Submitted (22-NOV-1998) Dermatology, Thomas Jefferson University,
233 South 10th Street, Philadelphia, PA 19107, USA
FEATURES Location/Qualifiers
source 1..6334
/db_xref="H-InvDB:HIT000069586"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="16"
/map="16p13.3; between D16S510 and D16S509"
gene 1..6334
/gene="UBN1"
5'UTR 1..701
/gene="UBN1"
CDS 702..4106
/gene="UBN1"
/note="nuclear transcriptional regulator; alternatively
spliced"
/codon_start=1
/product="ubinuclein"
/protein_id="AAF31756.1"
/translation="MSEPHRVQFTSLPGSLNPAFLKKSRKEEAGAGEQHQDCEPAAAA
VRITLTLFEPDHKRCPEFFYPELVKNIRGKVKGLQPGDKKKDLSDPFNDEEKERHKVE
ALARKFEEKYGGKKRRKDRIQDLIDMGYGYDESDSFIDNSEAYDELVPASLTTKYGGF
YINSGTLQFRQASESEDDFIKEKKKKSPKKRKLKEGGEKIKKKKKDDTYDKEKKSKKS
KFSKAGFTALNASKEKKKKKYSGALSVKEMLKKFQKEKEAQKKREEEHKPVAVPSAEV
QGLRELEGASDPLLSLFGSTSDNDLLQAATAMDSLTDLDLEHLLSESPEGSPFRDMDD
GSDSLGVGLDQEFRQPSSLPEGLPAPLEKRVKELAQAARAAEGESRQKFFTQDINGIL
LDIEAQTRELSSQVRSGVYAYLASFLPCSKDALLKRARKLHLYEQGGRLKEPLQKLKE
AIGRAMPEQMAKYQDECQAHTQAKVAKMLEEEKDKEQRDRICSDEEEDEEKGGRRIMG
PRKKFQWNDEIRELLCQVVKIKLESQDLERNNKAQAWEDCVKGFLDAEVKPLWPKGWM
QARTLFKESRRGHGHLTSILAKKKVMAPSKIKVKESSTKPDKKVSVPSGQIGGPIALP
SDHQTGGLSIGASSRELPSQASGGLANPPPVNLEDSLDEDLIRNPASSVEAVSKELAA
LNSRAAGNSEFTLPAPSKAPAEKVGGVLCTEEKRNLAKPSPSAPPPASSLQSPLNFLA
EQALALGQSSQEKKPESSGYKELSCQAPLNKGLPEVHQSKAKHHSLPRTSHGPQVAVP
VPGPQVKVFHAGTQQQKNFTPPSPFANKLQGPKASPTQCHRSLLQLVKTAAKGQGFHP
SAPATSGGLSASSSSSHKTPASSSSALSHPAKPHSVSSAGSSYKNNPFASSISKHGVS
SGSSSSGGTPVQSSVSGSLVPGIQPPSVGQPTSRPVPSSAGKKMPVSQKLTLVAPPGG
PNGDSSGGTQGVAKLLTSPSLKPSAVSSVTSSTSLSKGASGTVLLAGSSLMASPYKSS
SPKLSGAMSSNSLGIITPVPIPVHVLSFSADSSAKAGVSKDAIVTGPAPGSFHHGLGH
SLLAGLHSSPPHAAPLPHAAVPTHIPQSLPGASQLHGKGPAVPRKL"
3'UTR 4107..6334
/gene="UBN1"
regulatory 6307..6312
/regulatory_class="polyA_signal_sequence"
/gene="UBN1"
BASE COUNT 1592 a 1558 c 1667 g 1517 t
ORIGIN
1 ttctgtgaac atttggaatt ctgtattcaa atctattttg accattccca agtgattttg
61 aaggtctttg gcatgtcata atttgttatt ttgtcaaggc cagtgtttgg gtgtgagagt
121 ggtgcacagg gcaggagtgt gtaactttgt taggaagtga gcctagccac accctcctga
181 gtcactggtt ctttactatc ctggggtagg caatatcttt tgttcagctg ataaaagctt
241 tgtcattgtg aagattggct cccaatgata ggaaactgct ggtgatgaaa ataaaggggt
301 cttaaagatt attctcagcc agaaaaaata agtgttagac aaattaaatg gaaaataatt
361 aatattttag tagtctttac aatttggagg tctaaggctc tgtcagcatg ggttctttaa
421 ggtcaaggat ctaggataca catgcacagg aaaaaagact ggaagtatgc taagcagtga
481 ctatctctga atgattgtga aaaaatttag gatgaataag cagaaaaaaa caataaatga
541 caaaatataa caatggagtt ttcttgacaa tgaaattctc ttaaacttaa atctctttaa
601 ttaggcaggt aaactatttt atcatcttcg tttgacctgg cccttctttt caatgttaac
661 agaagccatg cagtgacacc cgctaagact tgttggtagc catgtcggag ccccacaggg
721 tccagttcac ctctctccca ggttccctga atcctgcgtt tttgaagaag tcccggaagg
781 aggaggctgg ggcaggagaa cagcatcagg actgtgagcc ggctgcagca gctgttcgga
841 ttacactcac cctctttgaa ccagatcaca aacgctgccc agagttcttc tacccagagc
901 tggtgaagaa tatccgaggg aaggtaaaag gccttcagcc tggagataag aagaaagatc
961 tgtcagatcc tttcaatgac gaagaaaagg aaaggcataa agtagaggcc cttgcccgaa
1021 aatttgaaga aaaatacggt ggaaagaaac gtagaaaaga ccgaatacag gacttgatcg
1081 atatggggta tggttatgat gaatccgact ccttcatcga taactctgag gcgtatgatg
1141 agcttgttcc tgcttctttg actacgaagt atggaggatt ttacattaac tcgggaaccc
1201 tgcagtttag acaagcatca gagtctgaag atgacttcat taaagaaaag aagaaaaaat
1261 ctccaaagaa gcggaagttg aaggaaggtg gtgagaagat aaagaagaag aaaaaagatg
1321 acacttatga caaggagaag aaatcgaaaa agtccaagtt ttccaaagcc ggcttcacag
1381 ccctcaatgc cagtaaggag aagaagaaga agaaatattc tggggcttta agcgttaaag
1441 agatgctaaa gaaatttcag aaagagaaag aggctcagaa aaaaagggag gaggagcata
1501 agcctgttgc ggtcccatca gcggaagttc agggcctgcg ggaactggag ggtgcctctg
1561 accccttgct ctcactcttt ggctctactt ctgacaacga cttgctccag gcggccactg
1621 ccatggactc gctgacggat ttggacttgg agcatctgct cagtgagtct ccagaaggaa
1681 gtcccttccg agatatggat gatggaagtg attcccttgg ggtgggattg gaccaggaat
1741 tcaggcagcc ctcttctctc cccgaaggcc tgccagcacc cctggagaag cgcgttaagg
1801 agctggctca ggctgccaga gctgctgagg gggagagcag acagaagttc ttcacccagg
1861 atattaatgg aatcctatta gacatagagg cgcagactcg ggagctgagc agtcaggtcc
1921 gctctggggt gtatgcctat cttgcgtcat tcctgccctg cagcaaggat gccctgctca
1981 agcgtgctcg gaaacttcac ctctatgaac aggggggccg tctgaaggag cctctccaga
2041 agctcaagga agccattggc agggcgatgc cagagcagat ggccaagtac caggacgaat
2101 gccaggcaca cacgcaggca aaggttgcca agatgctgga agaggagaaa gacaaggagc
2161 agagggaccg gatttgttcg gatgaggaag aagatgaaga aaaagggggc aggaggataa
2221 tgggacctcg gaagaagttc caatggaatg atgagatcag ggagctactg tgccaggtgg
2281 tgaagatcaa actggagagc caggacctgg agaggaacaa caaagcccag gcttgggagg
2341 actgtgtgaa gggctttctg gatgcggaag tcaagcccct ctggcccaaa ggctggatgc
2401 aggccagaac tctgtttaag gagagcagac gaggccatgg gcacctgact tcaatcctgg
2461 ccaagaagaa agttatggcc ccttctaaaa tcaaggtgaa ggagtcgtct acgaagcctg
2521 ataaaaaggt ttctgtccca tcaggacaga ttggtggccc cattgctttg ccctcagatc
2581 accaaacagg aggcctgagt attggggcct cgagcaggga gctcccatcc caggcatcgg
2641 gcggccttgc taaccctcct cctgtcaacc tggaggactc attggatgaa gacttgatcc
2701 gcaatccagc ctcctcggtg gaagccgtgt ccaaggaatt ggctgcattg aatagcagag
2761 cagctgggaa ctctgaattc acactgcctg caccctcaaa agcacctgca gaaaaagttg
2821 gaggcgtttt atgtacagaa gaaaaaagga acttggcgaa gcctagtcct tctgctccac
2881 caccagctag ctctctgcag tcacccctca attttctggc agaacaggct ctggcactgg
2941 ggcagtcctc tcaggagaaa aaaccagaga gttctggcta caaagagctg tcctgccagg
3001 ctcccctcaa taagggcctg ccagaagtac atcagtccaa agctaagcac cacagcttgc
3061 cacggacgtc tcacgggccc caagtggcag ttcctgtgcc tggcccccag gtcaaagtct
3121 ttcatgccgg cactcagcag cagaaaaact tcacgccccc atctccattt gccaataagc
3181 tccaaggccc aaaggcttct cccacacagt gtcatcgttc cctcctgcag ttagtgaaga
3241 cagcggccaa aggccagggc ttccatccct ctgcaccagc cacctcagga ggcctgtcag
3301 cctccagcag cagctctcac aagaccccag cctcgtcctc ttctgccctg agccatccag
3361 caaagccaca ttcagtcagc tctgcaggct catcttacaa gaataatccc tttgccagct
3421 caatctccaa acatggggtt tcttctggca gctcttcctc gggaggaaca ccagtccaga
3481 gttctgtttc tgggagcctg gtccctggca tacagcctcc ctccgtggga cagcccacca
3541 gccgacccgt cccaagttca gcagggaaaa aaatgcctgt ttcccagaag ttgactctgg
3601 tagcccctcc aggcggtcca aacggagatt ccagtggtgg gacccaggga gtggcaaagt
3661 tgctgacctc gccgtcccta aagccctctg cagttagtag tgtgacatcg tctacctcct
3721 tgtcaaaagg agcgagtggg actgtgctgc tggccggctc ctctttgatg gcttcaccct
3781 acaaatccag cagcccaaag ctgtctgggg ccatgagctc gaactccttg ggaattataa
3841 cccctgtccc tattcctgtc catgtgctct ccttcagcgc tgactcctct gccaaagcag
3901 gggtctccaa ggatgccatc gtcacaggcc ctgcccccgg gtccttccac catggccttg
3961 gccacagtct tctggctggc ttgcactcca gcccgcccca tgcagcgcct ctcccacacg
4021 ctgcggtgcc cacccatatc ccgcagagtc tgccaggtgc ttctcagctt catgggaaag
4081 ggcctgctgt accacggaaa ttgtgaccgc ttcagaggca aggcttgcca cttgggtctg
4141 ggtggaatca gaacgtgcag gtctcccagg atgtacactc actgcgccct ttctgctgct
4201 tggtgttctt ctggaggagc gtgagttctc agcggagcgc ttctcggcac ttctgatgtg
4261 cctcccatgg agggagccgg gcccttgctg ctcaggaggt gcagactgcc ccgtgctctg
4321 gcttgcagct ctgtcgctag acggttgtta gaggggcagc tctaggctgg ggcttgcgct
4381 gggccgtggt gggaggcaca gtgtttacag gctctggtgg cagagcagtt ggcacacctg
4441 tgggtgaatc tgcctgatcc cctggcattt ggtcagagta cctcagagca ccccactgct
4501 caggggctcc ttctggctgc agtaagctcc ctggatggtc acagtgccgc cccatcccca
4561 ggctgtgtgc tcaaagcgga caaaactcag gccagagcca cagctgggag acctgcactg
4621 tccctgcgaa atactaagaa cacctagggt gtgctcactg tgggggccag tttctcctcg
4681 gaacatgaca atgaagctct tttagagaaa agacctttgt agattcaaca attatgatag
4741 gatttttaca gacacctatt ttgggctcag ttttcatcat taccattaaa tgccattgga
4801 tagaagggga ctgttcttca cacatcatat tataggaaga cataattcca gtgcctttat
4861 ggtggagcag aattcgacaa cacatgtcca ttctgccctc tgaatggatc tgagacgaag
4921 accttttaaa agatatgtct gtattgaaga gaaagccagt tttgagtttt ctacacttgc
4981 acatcattat ctgtgccgtc ctgactagaa tgtgtctggg cccccaaatt ccatgtccct
5041 ttatatccat ggctcccatt ttgttttttc ccgagttcgt ggaggtggac tgcatagccc
5101 agagcccttc atctctctga gggtcaagga taccagggtc ccaagtcaca gatagacatt
5161 ccagtttgta ttcttaggaa tcattcttag gcagtgcggt ataatcaggc ctctgtgaag
5221 tgtctgccgg gtagaaatag gccttgaagt cctggggctc tccaggcagt ggggttatgt
5281 gtcgactgaa gggtgatgtg cagaagatct tggagagtgg atcagagaga ctaggacagt
5341 tactgcagag ctcctaagtc accactcaac cagtggctgt ttcacaagga tttgagggca
5401 cttgcctgtc ttgtgaggtc tgtgccacaa ggtgagtctg aactgactgc tccagctaag
5461 tgatcaggca cgttgagagt atatggtgtc ctcagcacat acacctgtgg gaaaacggac
5521 cgctcttggc tcctgactcc cagggtacag cgcccagtaa ctcatccttc attcagaggt
5581 ttgctggcct tcccggtttc ccaaggagca agacctctgt ctgccctttg gcccggcctc
5641 tgctctgact ccttttttta cataagaacc aatctgtgtt tcacattggg ctaagtggat
5701 tccttatccc tttgttatat atattttttg caacttggat ttccagtttg tttacagagt
5761 agtcttaggt agtagcaaaa gagccaaaga agagatttgt attgctgagc tcaaagccaa
5821 gcagaggccg gcagtggagg ctgagcaggg actctccagg cttctctgcc cataaacacc
5881 cgggtcccag gccctccttc ctttcccttt ggtgctccct cctccccatg taccattgcg
5941 cgtgcagctg gagcagaata ccctcatttt taggaatcta gtgatgcctc ttgcctcagg
6001 gaaacgtttc tttgatgggg agtttgagat ttcttttcct tgtttatgct ttatttgtgg
6061 taatgaaaga gcgaatgact gaacagccat ggcaaggcag acctacaggc gaggccgcag
6121 cagagggtgg ggcagagcag cctcggggtc tgggggctgc aggggtttcc ctggcgcagc
6181 gaaagtctct gagcacttac cgggcgtgac cgtttcttag gtgtgagagg ggctgtggct
6241 tttgtgcagc gactatgttg gtgttagggg tggtgtggag attgttaatc ttgtataaag
6301 caattcaata aattgtttca aggtttccaa aaca
//