LOCUS AF108460 5747 bp mRNA linear HUM 13-APR-2000
DEFINITION Homo sapiens ubinuclein (UBN1) mRNA, alternatively spliced,
complete cds.
ACCESSION AF108460
VERSION AF108460.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5747)
AUTHORS Aho,S., Buisson,M., Pajunen,T., Ryoo,Y.W., Giot,J.F., Gruffat,H.,
Sergeant,A. and Uitto,J.
TITLE Ubinuclein, a novel nuclear protein interacting with cellular and
viral transcription factors
JOURNAL J. Cell Biol. 148 (6), 1165-1176 (2000)
PUBMED 10725330
REFERENCE 2 (bases 1 to 5747)
AUTHORS Aho,S.
TITLE Direct Submission
JOURNAL Submitted (22-NOV-1998) Dermatology, Thomas Jefferson University,
233 South 10th Street, Philadelphia, PA 19107, USA
FEATURES Location/Qualifiers
source 1..5747
/db_xref="H-InvDB:HIT000069585"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="16"
/map="16p13.3; between D16S510 and D16S509"
gene 1..5747
/gene="UBN1"
5'UTR 1..114
/gene="UBN1"
CDS 115..3519
/gene="UBN1"
/note="nuclear transcriptional regulator; alternatively
spliced"
/codon_start=1
/product="ubinuclein"
/protein_id="AAF31755.1"
/translation="MSEPHRVQFTSLPGSLNPAFLKKSRKEEAGAGEQHQDCEPAAAA
VRITLTLFEPDHKRCPEFFYPELVKNIRGKVKGLQPGDKKKDLSDPFNDEEKERHKVE
ALARKFEEKYGGKKRRKDRIQDLIDMGYGYDESDSFIDNSEAYDELVPASLTTKYGGF
YINSGTLQFRQASESEDDFIKEKKKKSPKKRKLKEGGEKIKKKKKDDTYDKEKKSKKS
KFSKAGFTALNASKEKKKKKYSGALSVKEMLKKFQKEKEAQKKREEEHKPVAVPSAEV
QGLRELEGASDPLLSLFGSTSDNDLLQAATAMDSLTDLDLEHLLSESPEGSPFRDMDD
GSDSLGVGLDQEFRQPSSLPEGLPAPLEKRVKELAQAARAAEGESRQKFFTQDINGIL
LDIEAQTRELSSQVRSGVYAYLASFLPCSKDALLKRARKLHLYEQGGRLKEPLQKLKE
AIGRAMPEQMAKYQDECQAHTQAKVAKMLEEEKDKEQRDRICSDEEEDEEKGGRRIMG
PRKKFQWNDEIRELLCQVVKIKLESQDLERNNKAQAWEDCVKGFLDAEVKPLWPKGWM
QARTLFKESRRGHGHLTSILAKKKVMAPSKIKVKESSTKPDKKVSVPSGQIGGPIALP
SDHQTGGLSIGASSRELPSQASGGLANPPPVNLEDSLDEDLIRNPASSVEAVSKELAA
LNSRAAGNSEFTLPAPSKAPAEKVGGVLCTEEKRNLAKPSPSAPPPASSLQSPLNFLA
EQALALGQSSQEKKPESSGYKELSCQAPLNKGLPEVHQSKAKHHSLPRTSHGPQVAVP
VPGPQVKVFHAGTQQQKNFTPPSPFANKLQGPKASPTQCHRSLLQLVKTAAKGQGFHP
SAPATSGGLSASSSSSHKTPASSSSALSHPAKPHSVSSAGSSYKNNPFASSISKHGVS
SGSSSSGGTPVQSSVSGSLVPGIQPPSVGQPTSRPVPSSAGKKMPVSQKLTLVAPPGG
PNGDSSGGTQGVAKLLTSPSLKPSAVSSVTSSTSLSKGASGTVLLAGSSLMASPYKSS
SPKLSGAMSSNSLGIITPVPIPVHVLSFSADSSAKAGVSKDAIVTGPAPGSFHHGLGH
SLLAGLHSSPPHAAPLPHAAVPTHIPQSLPGASQLHGKGPAVPRKL"
3'UTR 3520..5747
/gene="UBN1"
regulatory 5720..5725
/regulatory_class="polyA_signal_sequence"
/gene="UBN1"
BASE COUNT 1392 a 1487 c 1561 g 1307 t
ORIGIN
1 cgccgccgcc cggggaccgg catgaggacc gccgcggggg gacgtctgcg gcccgcgtcg
61 gcgctgggga caaagaagcc atgcagtgac acccgctaag acttgttggt agccatgtcg
121 gagccccaca gggtccagtt cacctctctc ccaggttccc tgaatcctgc gtttttgaag
181 aagtcccgga aggaggaggc tggggcagga gaacagcatc aggactgtga gccggctgca
241 gcagctgttc ggattacact caccctcttt gaaccagatc acaaacgctg cccagagttc
301 ttctacccag agctggtgaa gaatatccga gggaaggtaa aaggccttca gcctggagat
361 aagaagaaag atctgtcaga tcctttcaat gacgaagaaa aggaaaggca taaagtagag
421 gcccttgccc gaaaatttga agaaaaatac ggtggaaaga aacgtagaaa agaccgaata
481 caggacttga tcgatatggg gtatggttat gatgaatccg actccttcat cgataactct
541 gaggcgtatg atgagcttgt tcctgcttct ttgactacga agtatggagg attttacatt
601 aactcgggaa ccctgcagtt tagacaagca tcagagtctg aagatgactt cattaaagaa
661 aagaagaaaa aatctccaaa gaagcggaag ttgaaggaag gtggtgagaa gataaagaag
721 aagaaaaaag atgacactta tgacaaggag aagaaatcga aaaagtccaa gttttccaaa
781 gccggcttca cagccctcaa tgccagtaag gagaagaaga agaagaaata ttctggggct
841 ttaagcgtta aagagatgct aaagaaattt cagaaagaga aagaggctca gaaaaaaagg
901 gaggaggagc ataagcctgt tgcggtccca tcagcggaag ttcagggcct gcgggaactg
961 gagggtgcct ctgacccctt gctctcactc tttggctcta cttctgacaa cgacttgctc
1021 caggcggcca ctgccatgga ctcgctgacg gatttggact tggagcatct gctcagtgag
1081 tctccagaag gaagtccctt ccgagatatg gatgatggaa gtgattccct tggggtggga
1141 ttggaccagg aattcaggca gccctcttct ctccccgaag gcctgccagc acccctggag
1201 aagcgcgtta aggagctggc tcaggctgcc agagctgctg agggggagag cagacagaag
1261 ttcttcaccc aggatattaa tggaatccta ttagacatag aggcgcagac tcgggagctg
1321 agcagtcagg tccgctctgg ggtgtatgcc tatcttgcgt cattcctgcc ctgcagcaag
1381 gatgccctgc tcaagcgtgc tcggaaactt cacctctatg aacagggggg ccgtctgaag
1441 gagcctctcc agaagctcaa ggaagccatt ggcagggcga tgccagagca gatggccaag
1501 taccaggacg aatgccaggc acacacgcag gcaaaggttg ccaagatgct ggaagaggag
1561 aaagacaagg agcagaggga ccggatttgt tcggatgagg aagaagatga agaaaaaggg
1621 ggcaggagga taatgggacc tcggaagaag ttccaatgga atgatgagat cagggagcta
1681 ctgtgccagg tggtgaagat caaactggag agccaggacc tggagaggaa caacaaagcc
1741 caggcttggg aggactgtgt gaagggcttt ctggatgcgg aagtcaagcc cctctggccc
1801 aaaggctgga tgcaggccag aactctgttt aaggagagca gacgaggcca tgggcacctg
1861 acttcaatcc tggccaagaa gaaagttatg gccccttcta aaatcaaggt gaaggagtcg
1921 tctacgaagc ctgataaaaa ggtttctgtc ccatcaggac agattggtgg ccccattgct
1981 ttgccctcag atcaccaaac aggaggcctg agtattgggg cctcgagcag ggagctccca
2041 tcccaggcat cgggcggcct tgctaaccct cctcctgtca acctggagga ctcattggat
2101 gaagacttga tccgcaatcc agcctcctcg gtggaagccg tgtccaagga attggctgca
2161 ttgaatagca gagcagctgg gaactctgaa ttcacactgc ctgcaccctc aaaagcacct
2221 gcagaaaaag ttggaggcgt tttatgtaca gaagaaaaaa ggaacttggc gaagcctagt
2281 ccttctgctc caccaccagc tagctctctg cagtcacccc tcaattttct ggcagaacag
2341 gctctggcac tggggcagtc ctctcaggag aaaaaaccag agagttctgg ctacaaagag
2401 ctgtcctgcc aggctcccct caataagggc ctgccagaag tacatcagtc caaagctaag
2461 caccacagct tgccacggac gtctcacggg ccccaagtgg cagttcctgt gcctggcccc
2521 caggtcaaag tctttcatgc cggcactcag cagcagaaaa acttcacgcc cccatctcca
2581 tttgccaata agctccaagg cccaaaggct tctcccacac agtgtcatcg ttccctcctg
2641 cagttagtga agacagcggc caaaggccag ggcttccatc cctctgcacc agccacctca
2701 ggaggcctgt cagcctccag cagcagctct cacaagaccc cagcctcgtc ctcttctgcc
2761 ctgagccatc cagcaaagcc acattcagtc agctctgcag gctcatctta caagaataat
2821 ccctttgcca gctcaatctc caaacatggg gtttcttctg gcagctcttc ctcgggagga
2881 acaccagtcc agagttctgt ttctgggagc ctggtccctg gcatacagcc tccctccgtg
2941 ggacagccca ccagccgacc cgtcccaagt tcagcaggga aaaaaatgcc tgtttcccag
3001 aagttgactc tggtagcccc tccaggcggt ccaaacggag attccagtgg tgggacccag
3061 ggagtggcaa agttgctgac ctcgccgtcc ctaaagccct ctgcagttag tagtgtgaca
3121 tcgtctacct ccttgtcaaa aggagcgagt gggactgtgc tgctggccgg ctcctctttg
3181 atggcttcac cctacaaatc cagcagccca aagctgtctg gggccatgag ctcgaactcc
3241 ttgggaatta taacccctgt ccctattcct gtccatgtgc tctccttcag cgctgactcc
3301 tctgccaaag caggggtctc caaggatgcc atcgtcacag gccctgcccc cgggtccttc
3361 caccatggcc ttggccacag tcttctggct ggcttgcact ccagcccgcc ccatgcagcg
3421 cctctcccac acgctgcggt gcccacccat atcccgcaga gtctgccagg tgcttctcag
3481 cttcatggga aagggcctgc tgtaccacgg aaattgtgac cgcttcagag gcaaggcttg
3541 ccacttgggt ctgggtggaa tcagaacgtg caggtctccc aggatgtaca ctcactgcgc
3601 cctttctgct gcttggtgtt cttctggagg agcgtgagtt ctcagcggag cgcttctcgg
3661 cacttctgat gtgcctccca tggagggagc cgggcccttg ctgctcagga ggtgcagact
3721 gccccgtgct ctggcttgca gctctgtcgc tagacggttg ttagaggggc agctctaggc
3781 tggggcttgc gctgggccgt ggtgggaggc acagtgttta caggctctgg tggcagagca
3841 gttggcacac ctgtgggtga atctgcctga tcccctggca tttggtcaga gtacctcaga
3901 gcaccccact gctcaggggc tccttctggc tgcagtaagc tccctggatg gtcacagtgc
3961 cgccccatcc ccaggctgtg tgctcaaagc ggacaaaact caggccagag ccacagctgg
4021 gagacctgca ctgtccctgc gaaatactaa gaacacctag ggtgtgctca ctgtgggggc
4081 cagtttctcc tcggaacatg acaatgaagc tcttttagag aaaagacctt tgtagattca
4141 acaattatga taggattttt acagacacct attttgggct cagttttcat cattaccatt
4201 aaatgccatt ggatagaagg ggactgttct tcacacatca tattatagga agacataatt
4261 ccagtgcctt tatggtggag cagaattcga caacacatgt ccattctgcc ctctgaatgg
4321 atctgagacg aagacctttt aaaagatatg tctgtattga agagaaagcc agttttgagt
4381 tttctacact tgcacatcat tatctgtgcc gtcctgacta gaatgtgtct gggcccccaa
4441 attccatgtc cctttatatc catggctccc attttgtttt ttcccgagtt cgtggaggtg
4501 gactgcatag cccagagccc ttcatctctc tgagggtcaa ggataccagg gtcccaagtc
4561 acagatagac attccagttt gtattcttag gaatcattct taggcagtgc ggtataatca
4621 ggcctctgtg aagtgtctgc cgggtagaaa taggccttga agtcctgggg ctctccaggc
4681 agtggggtta tgtgtcgact gaagggtgat gtgcagaaga tcttggagag tggatcagag
4741 agactaggac agttactgca gagctcctaa gtcaccactc aaccagtggc tgtttcacaa
4801 ggatttgagg gcacttgcct gtcttgtgag gtctgtgcca caaggtgagt ctgaactgac
4861 tgctccagct aagtgatcag gcacgttgag agtatatggt gtcctcagca catacacctg
4921 tgggaaaacg gaccgctctt ggctcctgac tcccagggta cagcgcccag taactcatcc
4981 ttcattcaga ggtttgctgg ccttcccggt ttcccaagga gcaagacctc tgtctgccct
5041 ttggcccggc ctctgctctg actccttttt ttacataaga accaatctgt gtttcacatt
5101 gggctaagtg gattccttat ccctttgtta tatatatttt ttgcaacttg gatttccagt
5161 ttgtttacag agtagtctta ggtagtagca aaagagccaa agaagagatt tgtattgctg
5221 agctcaaagc caagcagagg ccggcagtgg aggctgagca gggactctcc aggcttctct
5281 gcccataaac acccgggtcc caggccctcc ttcctttccc tttggtgctc cctcctcccc
5341 atgtaccatt gcgcgtgcag ctggagcaga ataccctcat ttttaggaat ctagtgatgc
5401 ctcttgcctc agggaaacgt ttctttgatg gggagtttga gatttctttt ccttgtttat
5461 gctttatttg tggtaatgaa agagcgaatg actgaacagc catggcaagg cagacctaca
5521 ggcgaggccg cagcagaggg tggggcagag cagcctcggg gtctgggggc tgcaggggtt
5581 tccctggcgc agcgaaagtc tctgagcact taccgggcgt gaccgtttct taggtgtgag
5641 aggggctgtg gcttttgtgc agcgactatg ttggtgttag gggtggtgtg gagattgtta
5701 atcttgtata aagcaattca ataaattgtt tcaaggtttc caaaaca
//