LOCUS AF108388 2883 bp mRNA linear HUM 13-MAR-2001
DEFINITION Homo sapiens sodium/calcium exchanger isoform NaCa7 (NCX1) mRNA,
complete cds.
ACCESSION AF108388
VERSION AF108388.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2883)
AUTHORS Van Eylen,F., Bollen,A. and Herchuelz,A.
TITLE NCX1 Na/Ca exchanger splice variants in pancreatic islet cells
JOURNAL J. Endocrinol. 168 (3), 517-526 (2001)
PUBMED 11241183
REFERENCE 2 (bases 1 to 2883)
AUTHORS Van Eylen,F., Bollen,A. and Herchuelz,A.
TITLE Direct Submission
JOURNAL Submitted (23-NOV-1998) Pharmacodynamie, Brussels Free University,
Route de Lennik 808, C.P. 617, Brussels 1070, Belgium
FEATURES Location/Qualifiers
source 1..2883
/db_xref="H-InvDB:HIT000069583"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
gene 1..2883
/gene="NCX1"
CDS 1..2883
/gene="NCX1"
/note="isoform NCX1.7"
/codon_start=1
/product="sodium/calcium exchanger isoform NaCa7"
/protein_id="AAF08987.1"
/translation="MYNMRRLSLSPTFSMGFHLLVTVSLLFSHVDHVIAETEMEGEGN
ETGECTGSYYCKKGVILPIWEPQDPSFGDKIARATVYFVAMVYMFLGVSIIADRFMSS
IEVITSQEKEITIKKPNGETTKTTVRIWNETVSNLTLMALGSSAPEILLSVIEVCGHN
FTAGDLGPSTIVGSAAFNMFIIIALCVYVVPDGETRKIKHLRVFFVTAAWSIFAYTWL
YIILSVISPGVVEVWEGLLTFFFFPICVVFAWVADRRLLFYKYVYKRYRAGKQRGMII
EHEGDRPSSKTEIEMDGKVVNSHVENFLDGALVLEVDERDQDDEEARREMARILKELK
QKHPDKEIEQLIELANYQVLSQQQKSRAFYRIQATRLMTGAGNILKRHAADQARKAVS
MHEVNTEVTENDPVSKIFFEQGTYQCLENCGTVALTIIRRGGDLTNTVFVDFRTEDGT
ANAGSDYEFTEGTVVFKPGDTQKEIRVGIIDDDIFEEDENFLVHLSNVKVSSEASEDG
ILEANHVSTLACLGSPSTATVTIFDDDHAGIFTFEEPVTHVSESIGIMEVKVLRTSGA
RGNVIVPYKTIEGTARGGGEDFEDTCGELEFQNDEIVKIITIRIFDREEYEKECSFSL
VLEEPKWIRRGMKGGFTITGQPVFRKVHAREHPILSTVITIADEYDDKQPLTSKEEEE
RRIAEMGRPILGEHTKLEVIIEESYEFKSTVDKLIKKTNLALVVGTNSWREQFIEAIT
VSAGEDDDDDECGEEKLPSCFDYVMHFLTVFWKVLFAFVPPTEYWNGWACFIVSILMI
GLLTAFIGDLASHFGCTIGLKDSVTAVVFVALGTSVPDTFASKVAATQDQYADASIGN
VTGSNAVNVFLGIGVAWSIAAIYHAANGEQFKVSPGTLAFSVTLFTIFAFINVGVLLY
RRRPEIGGELGGPRTAKLLTSCLFVLLWLLYIFFSSLEAYCHIKGF"
BASE COUNT 772 a 598 c 731 g 782 t
ORIGIN
1 atgtacaaca tgcggcgatt aagtctttca cccacctttt caatgggatt tcatctgtta
61 gttactgtga gtctcttatt ttcccatgtg gaccatgtaa ttgctgagac agaaatggaa
121 ggagaaggaa atgaaactgg tgaatgtact ggatcatatt actgtaagaa aggggtgatt
181 ttgcccattt gggaacccca agacccttct tttggggaca aaattgctag agctactgtg
241 tattttgtgg ccatggtcta catgtttctt ggagtctcta tcatagctga tcggttcatg
301 tcctctatag aagtcatcac atctcaagaa aaagaaataa ccataaagaa acccaatgga
361 gagaccacca agacaactgt gaggatctgg aatgaaacag tttctaacct gaccttgatg
421 gccctgggat cttctgctcc tgagattctc ctttcagtaa ttgaagtgtg tggccataac
481 ttcactgcag gagacctcgg tcctagcacc atcgtgggaa gtgctgcatt caatatgttc
541 atcattattg cactctgtgt ttatgtggtg cctgacggag agacaaggaa gattaagcat
601 ttgcgtgtct tctttgtgac agcagcctgg agcatctttg cctacacctg gctttacatt
661 attttgtctg tcatatctcc tggtgttgtg gaggtctggg aaggtttgct tactttcttc
721 ttctttccca tctgtgttgt gttcgcttgg gtagcggata ggagacttct gttttacaag
781 tatgtctaca agaggtatcg agctggcaag cagaggggga tgattattga acatgaagga
841 gacaggccat cttctaagac tgaaattgaa atggacggga aagtggtcaa ttctcatgtt
901 gaaaatttct tagatggtgc tctggttctg gaggtggatg agagggacca agatgatgaa
961 gaagctaggc gagaaatggc taggattctg aaggaactta agcagaagca tccagataaa
1021 gaaatagagc aattaataga attagctaac taccaagtcc taagtcagca gcaaaaaagt
1081 agagcatttt atcgcattca agctactcgc ctcatgactg gagctggcaa cattttaaag
1141 aggcatgcag ctgaccaagc aaggaaggct gtcagcatgc acgaggtcaa cactgaagtg
1201 actgaaaatg accctgttag taagatcttc tttgaacaag ggacatatca gtgtctggag
1261 aactgtggta ctgtggccct taccattatc cgcagaggtg gtgatttgac taacactgtg
1321 tttgttgact tcagaacaga ggatggcaca gcaaatgctg ggtctgatta tgaatttact
1381 gaaggaactg tggtgtttaa gcctggtgat acccagaagg aaatcagagt gggtatcata
1441 gatgatgata tctttgagga ggatgaaaat ttccttgtgc atctcagcaa tgtcaaagta
1501 tcttctgaag cttcagaaga tggcatactg gaagccaatc atgtttctac acttgcttgc
1561 ctcggatctc cctccactgc cactgtaact atttttgatg atgaccacgc aggcattttt
1621 acttttgagg aacctgtgac tcatgtgagt gagagcattg gcatcatgga ggtgaaagta
1681 ttgagaacat ctggagctcg aggaaatgtt atcgttccat ataaaaccat cgaagggact
1741 gccagaggtg gaggggagga ttttgaggac acttgtggag agctcgaatt ccagaatgat
1801 gaaattgtga agatcattac cattagaata tttgaccgtg aggaatatga gaaagagtgc
1861 agtttctccc ttgtgcttga ggaaccaaaa tggataagaa gaggaatgaa aggtggcttc
1921 acaataacag gccaacctgt cttcaggaag gttcatgcta gagaacatcc gattctctct
1981 actgtaatca ccattgcaga cgaatatgat gacaagcagc cactgaccag caaagaggaa
2041 gaggagaggc gcattgcaga aatggggcgc cccatcctgg gagagcacac caagttggaa
2101 gtgatcattg aagaatccta tgaattcaag agtactgtgg acaaactcat taagaagaca
2161 aacctggccc ttgtggttgg gactaacagc tggagagaac agttcattga agctatcact
2221 gtcagtgctg gggaagatga tgacgacgat gaatgtgggg aagagaagct gccctcctgt
2281 ttcgattacg tgatgcactt tctgactgtg ttctggaagg tcctgtttgc cttcgtcccc
2341 cctactgaat actggaatgg ctgggcgtgt ttcattgtct ccatcctcat gattggccta
2401 ctgacagctt tcattggaga cctggcttcc cactttggct gcaccattgg cctgaaagat
2461 tctgtgactg cagtcgtgtt cgtcgcactt ggaacatcag tgccagacac atttgccagc
2521 aaagtggcag ccacccagga ccagtatgca gacgcctcca taggtaacgt cacgggcagc
2581 aacgcggtga atgtcttcct gggaatcggt gtggcctggt ccatcgctgc catctaccac
2641 gcagccaatg gggaacagtt caaagtgtcc cctggcacac tagctttctc tgtcactctc
2701 ttcaccattt ttgctttcat caatgtgggg gtgctgctgt atcggcggag gccagaaatc
2761 ggaggtgagc tgggtgggcc ccggactgcc aagctcctca catcctgcct ctttgtgctc
2821 ctatggctct tgtacatttt cttctcctcc ctggaggcct actgccacat aaaaggcttc
2881 taa
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