LOCUS AF106071 2412 bp mRNA linear HUM 19-DEC-1998
DEFINITION Homo sapiens ras activator RasGRP (RASGRP) mRNA, complete cds.
ACCESSION AF106071
VERSION AF106071.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2412)
AUTHORS Bottorff,D.A., Ebinu,J. and Stone,J.C.
TITLE RasGRP, a Ras activator: murine and human cDNA sequences,
chromosomal positions and related genes
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 2412)
AUTHORS Bottorff,D.A., Ebinu,J. and Stone,J.C.
TITLE Direct Submission
JOURNAL Submitted (12-NOV-1998) Biochemistry, Univ. of Alberta, 5-65
Medical Sciences Bldg., Edmonton, Alta T6T-2H7, Canada
FEATURES Location/Qualifiers
source 1..2412
/db_xref="H-InvDB:HIT000069499"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="15"
/map="15q15"
/cell_type="Jurkat T cell"
gene 1..2412
/gene="RASGRP"
CDS 13..2406
/gene="RASGRP"
/note="similar to Rattus norvegicus RasGRP"
/codon_start=1
/product="ras activator RasGRP"
/protein_id="AAC97349.1"
/translation="MGTLGKAREAPRKPSHGCRAASKARLEAKPANSPFPSHPSLAHI
TQFRMMVSLGHLAKGASLDDLIDSCIQSFDADGNLCRSNQLLQVMLTMHRIVISSAEL
LQKVITLYKDALAKNSPGLCLKICYFVRYWITEFWVMFKMDASLTDTMEEFQELVKAK
GEELHCRLIDTTQINARDWSRKLTQRIKSNTSKKRKVSLLFDHLEPEELSEHLTYLEF
KSFRRISFSDYQNYLVNSCVKENPTMERSIALCNGISQWVQLMVLSRPTPQLRAEVFI
KFIQVAQKLHQLQNFNTLMAVIGGLCHSSISRLKETSSHVPHEINKVLGEMTELLSSS
RNYDNYRRAYGECTDFKIPILGVHLKDLISLYEAMPDYLEDGKVNVHKLLALYNHISE
LVQLQEVAPPLEANKDLVHLLTLSLDLYYTEDEIYELSYAREPRNHRAPPLTPSKPPV
VVDWASGVSPKPDPKTISKHVQRMVDSVFKNYDHDQDGYISQEEFEKIAASFPFSFCV
MDKDREGLISRDEITAYFMRASSIYSKLGLGFPHNFQETTYLKPTFCDNCAGFLWGVI
KQGYRCKDCGMNCHKQCKDLVVFECKKRAKNPVAPTENNTSVGPVSNLCSLGAKDLLH
APEEGPFTFPNGEAVEHGEESKDRTIMLMGVSSQKISLRLKRAVAHKATQTESQPWIG
SEGPSGPFVLSSPRKTAQDTLYVLPSPTSPCPSPVLVRKRAFVKWENKDSLIKSKEEL
RHLRLPTYQELEQEINTLKADNDALKIQLKYAQKKIESLQLEKSNHVLAQMEQGDCS"
BASE COUNT 673 a 617 c 568 g 554 t
ORIGIN
1 ggatccgcgg ccatgggaac cctgggcaag gcgagagagg ctccgcggaa accttcccat
61 ggctgcagag ctgcctctaa agcaagacta gaggcaaagc cagccaacag ccccttcccc
121 tcccatccca gcttggccca catcacccag ttccgaatga tggtgtctct gggacattta
181 gccaaaggag ccagcctgga cgatctcatt gacagctgca ttcaatcttt tgatgcagat
241 ggaaacctgt gtcgaagtaa ccaactgttg caagtcatgc tgaccatgca ccgaattgtc
301 atctcctctg cagaactgct ccaaaaagtt atcaccctct ataaggatgc tttggcaaag
361 aattcaccag gactttgcct gaagatctgt tattttgtaa ggtattggat aacagaattc
421 tgggtcatgt ttaaaatgga cgccagcttg acagacacta tggaggagtt tcaggaactg
481 gtgaaagcta agggtgagga gttacattgc cgcctgattg acacaactca aatcaatgcc
541 cgtgactggt ccaggaaact tactcaaagg ataaaatcaa ataccagcaa gaaacggaaa
601 gtctccctgc tctttgacca tctggaacca gaagagctat ccgagcacct cacctacctt
661 gagttcaagt ctttccggag gatatcgttc tctgattatc agaattacct tgtaaatagc
721 tgtgtgaagg aaaaccccac catggagcga tctattgctc tgtgcaacgg catctcccag
781 tgggtacaac tgatggttct cagccgcccc acgccgcagc tccgagcaga agtcttcatc
841 aagttcatcc aggtggctca gaagctccac caactacaga acttcaatac actgatggct
901 gtgataggtg ggctgtgtca cagctcaatc tcgaggctca aggagacaag ttcgcatgtc
961 ccacatgaaa tcaataaggt tctcggtgag atgactgagc tgctgtcctc ctccagaaac
1021 tacgacaatt accggcgagc ctatggagag tgcaccgact tcaagatccc cattctgggt
1081 gtgcatctca aggacctcat ctccctgtat gaagccatgc ctgactatct ggaggacggg
1141 aaagtgaacg tccataagct actggcccta tacaatcata tcagtgaatt ggtccagctg
1201 caagaggtgg ccccaccctt ggaggctaac aaggacttgg tacacttgct gacgttatcc
1261 ctggatcttt actacactga ggatgaaatc tatgagcttt cctatgcccg ggaaccaagg
1321 aaccacagag ctccaccact aacaccttca aagccaccag tagtagtgga ctgggcttct
1381 ggagtgtctc ccaaacctga tccaaaaacc attagcaaac acgtccagag gatggtggat
1441 tctgtcttca agaactatga tcacgaccag gatggataca tttctcagga agaatttgaa
1501 aagattgctg cgagttttcc attttccttc tgtgtgatgg acaaagacag ggaaggcctc
1561 atcagcaggg atgagatcac agcctacttc atgagagcca gctcaatcta ttccaagctg
1621 ggcctgggct ttcctcacaa cttccaagag accacctacc tgaagcccac tttttgtgac
1681 aactgtgctg gatttctctg gggagtgatc aaacaaggat atcgatgtaa agactgcggg
1741 atgaactgtc acaaacaatg caaagatctg gttgtgtttg agtgtaagaa gcgagccaag
1801 aacccagtag ctcccacaga gaacaacact tctgtggggc cagtgtccaa cctttgctca
1861 ttgggagcca aagatctgct ccatgcacct gaggaaggac cttttacatt ccctaatggg
1921 gaggctgtgg aacatggtga ggagagtaag gatcggacca tcatgctgat gggagtgtcc
1981 tcacagaaga tttctcttcg gctgaagagg gctgttgccc acaaggccac ccagactgaa
2041 tcacagcctt ggattggcag tgagggccct tcaggtccct ttgtgctgtc ttccccaagg
2101 aagacagccc aggatactct atatgtgctt cccagtccca cctctccatg tcctagccca
2161 gtcttggtca gaaagcgggc ttttgtcaag tgggagaata aagactccct cataaaatca
2221 aaggaggagc tccgtcacct cagactgcct acctaccaag aactggaaca ggaaataaat
2281 actctgaaag cagataatga tgccctaaag atccaactga aatatgcaca gaagaaaata
2341 gaatccctcc agcttgaaaa aagcaatcat gtcttagctc aaatggagca gggtgactgt
2401 tcttagccca ga
//