LOCUS AF106069 4611 bp mRNA linear HUM 01-SEP-1999
DEFINITION Homo sapiens deubiquitinating enzyme (UNPH4) mRNA, complete cds.
ACCESSION AF106069
VERSION AF106069.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4611)
AUTHORS Kim,K.I., Nagase,T. and Chung,C.H.
TITLE Identification and characterization of a new human deubiquitinating
enzyme Unph4
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 4611)
AUTHORS Kim,K.I., Nagase,T. and Chung,C.H.
TITLE Direct Submission
JOURNAL Submitted (12-NOV-1998) Molecular Biology, Seoul National
University, Shinlim-dong, Kwanak-ku, Seoul 151-742, South Korea
FEATURES Location/Qualifiers
source 1..4611
/db_xref="H-InvDB:HIT000069498"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/tissue_type="brain"
gene 1..4611
/gene="UNPH4"
CDS 10..2868
/gene="UNPH4"
/note="ubiquitin-specific cysteine protease"
/codon_start=1
/product="deubiquitinating enzyme"
/protein_id="AAD52099.1"
/translation="MAEGGAADLDTQRSDIATLLKTSLRKGDTWYLVDSRWFKQWKKY
VGFDSWDKYQMGDQNVYPGPIDNSGLLKDGDAQSLKEHLIDELDYILLPTEGWNKLVS
WYTLMEGQEPIARKVVEQGMFVKHCKVEVYLTELKLCENGNMNNVVTRRFSKADTIDT
IEKEIRKIFSIPDEKETRLWNKYMSNTFEPLNKPDSTIQDAGLYQGQVLVIEQKNEDG
TWPRGPSTPNVKNSNYCLPSYTAYKNYDYSEPGRNNEQPGLCGLSNLGNTCFMNSAIQ
CLSNTPPLTEYFLNDKYQEELNFDNPLGMRGEIAKSYAELIKQMWSGKFSYVTPRAFK
TQVGRFAPQFSGYQQQDCQELLAFLLDGLHEDLNRIRKKPYIQLKDADGRPDKVVAEE
AWENHLKRNDSIIVDIFHGLFKSTLVCPECAKISVTFDPFCYLTLPLPMKKERTLEVY
LVRMDPLTKPMQYKVVVPKIGNILDLCTALSALSGIPADKMIVTDIYNHRFHRIFAMD
ENLSSIMERDDIYVFEININRTEDTEHVIIPVCLREKFRHSSYTHHTGSSLFGQPFLM
AVPRNNTEDKLYNLLLLRMCRYVKISTETEETEGSLHCCKDQNINGNGPNGIHEEGSP
SEMETDEPDDESSQDQELPSENENSQSEDSVGGDNDSENGLCTEDTCKGQLTGHKKRL
FTFQFNNLGNTDINYIKDDTRHIRFDDRQLRLDERSFLALDWDPDLKKRYFDENAAED
FEKHESVEYKPPKKPFVKLKDCIELFTTKEKLGAEDPWYCPNCKEHQQATKKLDLWSL
PPVLVVHLKRFSYSRYMRDKLDTLVDFPINDLDMSEFLINPNAGPCRYNLIAVSNHYG
GMGGGHYTAFAKNKDDGKWYYFDDSSVSTASEDQIVSKAAYVLFYQRQDTFSGTGFFP
LDRETKGASAATGIPLESDEDSNDNDNDIENENCMHTN"
BASE COUNT 1529 a 784 c 886 g 1412 t
ORIGIN
1 tggaagaaga tggcggaagg cggagcggcg gatctggaca cccagcggtc tgacatcgcg
61 acgctgctca aaacctcgct ccggaaaggg gacacctggt acctagtcga tagtcgctgg
121 ttcaaacagt ggaaaaaata tgttggcttt gacagttggg acaaatacca gatgggagat
181 caaaatgtgt atcctggacc cattgataac tctggacttc tcaaagatgg tgatgcccag
241 tcacttaagg aacatcttat tgatgaattg gattacatac tgttgccaac tgaaggttgg
301 aataaacttg tcagctggta cacattgatg gaaggtcaag agccaatagc acgaaaggtg
361 gttgaacagg gtatgtttgt aaagcactgc aaagtagaag tatatctcac agaattgaag
421 ctatgtgaaa atggaaacat gaataatgtt gtaactcgaa gatttagcaa agctgacaca
481 atagatacaa ttgaaaagga aataagaaaa atcttcagta ttccagatga aaaggagacc
541 agattgtgga acaaatacat gagtaacaca tttgaaccac tgaataaacc agacagcacc
601 attcaggatg ctggtttata ccaaggacag gtattagtga tagaacagaa aaatgaagat
661 ggaacatggc caaggggtcc ttctactcct aatgtgaaaa actcaaatta ctgtcttcca
721 tcatataccg cttataagaa ctatgattat tcggaacctg gaagaaacaa tgaacagcca
781 ggcctctgtg gcctaagtaa cttgggaaat acgtgtttca tgaactcagc tattcagtgt
841 ttgagcaaca cacctccact tactgagtat ttcctcaatg ataagtatca agaagaactg
901 aattttgaca atcccttagg aatgagaggt gaaatagcta aatcttatgc cgaactgatc
961 aagcaaatgt ggtctggaaa gtttagctac gtcaccccaa gagcctttaa gacacaggta
1021 ggacgttttg cacctcagtt ctctggatat cagcagcaag actgtcaaga actgttagct
1081 ttcctattag atggattaca tgaggatttg aatagaatta ggaaaaaacc atatatacaa
1141 ttaaaagatg cagatggaag gccagataag gtggttgccg aagaagcctg ggaaaaccat
1201 ttaaaacgaa atgattctat catagtagat atatttcatg gccttttcaa atcaacttta
1261 gtttgtcctg agtgtgctaa gatttcagta acatttgatc ctttttgtta cttgacactt
1321 ccattgccca tgaaaaaaga acgcaccttg gaagtttact tagttagaat ggatccgctt
1381 accaaaccta tgcagtacaa agtggttgtc cccaaaattg gaaacatatt agatctttgt
1441 acagcattgt ctgctttgtc aggaatacct gcagataaga tgatagttac tgatatatac
1501 aatcatagat ttcacagaat attcgctatg gatgaaaacc ttagtagtat tatggaacgg
1561 gatgatattt atgtgtttga aattaacatc aataggacag aagatacaga gcacgtgatt
1621 attcctgttt gcctaagaga aaaattcaga cactcgagtt atacccacca tactggttct
1681 tcactttttg gtcagccctt tcttatggct gtaccacgaa acaatactga agacaaactt
1741 tataatctcc tgctcttgag aatgtgccga tatgtcaaaa tatctactga aactgaagaa
1801 actgaaggat ccctacactg ctgtaaggac caaaatatta atgggaatgg cccaaatggc
1861 atacatgaag aaggctcacc aagtgaaatg gaaacagatg agccagatga tgaatccagc
1921 caggatcaag aacttccctc agagaatgaa aacagtcagt ctgaagattc agttggagga
1981 gataatgatt ctgaaaatgg attatgtact gaggatactt gcaaaggtca actcacggga
2041 cacaaaaaac gattgtttac attccagttc aacaacttag gcaatactga tatcaactac
2101 atcaaagatg ataccaggca tataagattt gatgataggc agcttaggct agatgaaaga
2161 tcttttcttg ctttggattg ggatcctgat ttgaaaaaaa gatattttga tgaaaatgct
2221 gctgaggact ttgaaaaaca tgaaagtgtg gagtataaac ctcctaaaaa accctttgtg
2281 aaattaaaag attgcattga actttttaca acaaaagaaa agctaggtgc tgaagatccc
2341 tggtattgtc cgaattgtaa agaacatcag caagccacaa agaaattgga tttatggtcc
2401 ctgcctccag tacttgtagt acatctcaag cgattttctt acagtcgata catgagagac
2461 aagttggata ccttagttga ttttcctatc aatgacttgg atatgtcgga attcttaatt
2521 aatccaaatg caggtccttg ccgctataat ctgattgctg tttccaacca ctatggaggg
2581 atgggaggag gacactatac tgcttttgca aaaaataaag atgatggaaa atggtactat
2641 tttgatgaca gtagtgtctc cactgcatct gaagaccaaa ttgtgtccaa agcagcatat
2701 gtactcttct accagagaca agacactttc agtggaactg gcttttttcc tcttgaccga
2761 gaaactaaag gtgcttcagc tgccactggc atcccattag aaagtgatga agatagcaat
2821 gataatgaca atgatataga aaatgaaaac tgtatgcaca ctaactaatg aaagtcctag
2881 aagccataaa agagacactt tcctgctggt ggtatctatg gaaatgatga agttacccac
2941 cacattaaaa caaaagtctg agatggggag tttcagataa ccgaatgtaa atcctttatc
3001 agattttaac ttgtgcagta cttgaagtga aacacaatga aaactttaac agaaattgtc
3061 tcttaataca tttacagtct tgtatttaca agctaaatat atataggaaa tcacaaataa
3121 atccctttta agtttgctgc tgttttgatt aattatgttt cctttaattt tttggatgtg
3181 agttgatgac aaatgttaaa tttgtggatg ttggtcattt attttgctct aataatactg
3241 caagaaaact atggctgaac ttagtttttg gataatctag ttcatgtgca ttaggctgcc
3301 gtatatacta ctatgatatt tagctgcagt atcaatgtgg cataaatact gcggcagcat
3361 tcttcgaaaa ccgcattttc aaatttatcc ccgtaatcaa tgtgggccta ttaaaaaacc
3421 aaatcatgat acaagaaaca accttggaaa agttatttcc ctttgtaata cctttaaaaa
3481 tccagagtat tatattcatt ttactgccac tgtggaaaca ggttctagat ttcatactcc
3541 atctaaagtc atttttcagt tacatgtaag tattatttac tgctattggg atctattctt
3601 cagatattca aaaacatttt ttgctttaaa atgcatatct ttaattgggt gttggtccaa
3661 aattaaaatt tttgctgtct gtttttctct accccatttt gtggtaattt ggcaacttga
3721 gctctcccaa ttattgtaat ataaggacag acataatagt attctgtacc catagtaata
3781 attgcatcaa gcttagatga gaaatttttt tcatatactg gcctttaaat cattaatgga
3841 caattggcta taaaggtagg tctgttaact ttctttgtgt gttcctgatg gaattcacca
3901 tagccttaca gcttttctca gaaggtaact tgttataaga gaaatggcat ttgcatgttc
3961 cagagtcaga acctgtacag tatataaagc ataaacacct tgaatttgat tttagttcac
4021 cacattcaag gatccaggat gccaaaaata tgtgtgaaca tttgaaacat ttttatttgc
4081 tgctttttcc ctttgatata gttgaaagaa tgtattgtaa attggcatac aatactgcct
4141 ttaatagaaa acctaaatgc tggggcacat ttcacatatc gactacctga gaaattgctt
4201 tgtgtcccac tgttattaaa gcaaaaagta taatgttctt cacttgaact aatcaaatac
4261 aatagattat aaattgtgta ttgtaaataa aagttcactc tgtgagtgca cattttggta
4321 aattatttat ttatgttagc atttaaaagt ttaaaaaaaa tgcatttgac caggataaat
4381 gaggtatgtt gatcatggct ttgctttata tcttgatatt aaagctggtt tatcatcctg
4441 gtattttaaa agctgctttg gggttttttt tttctttttt ttttttttaa tgtaaactaa
4501 cctcctgcat gacagaggtt aaaattttgt ctgcacttga gttcacttga gtttacattt
4561 gaaatgtgca tgtttattta tatagatttc aataaagcta ttcaaggcct t
//