LOCUS AF105365 5239 bp mRNA linear HUM 20-JUN-1999
DEFINITION Homo sapiens K-Cl cotransporter KCC4 mRNA, complete cds.
ACCESSION AF105365
VERSION AF105365.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5239)
AUTHORS Mount,D.B., Mercado,A., Song,L., Xu,J., George,A.L. Jr., Delpire,E.
and Gamba,G.
TITLE Cloning and characterization of KCC3 and KCC4, new members of the
cation-chloride cotransporter gene family
JOURNAL J. Biol. Chem. 274 (23), 16355-16362 (1999)
PUBMED 10347194
REFERENCE 2 (bases 1 to 5239)
AUTHORS Mount,D.B.
TITLE Direct Submission
JOURNAL Submitted (10-NOV-1998) Division of Nephrology, Department of
Medicine, Vanderbilt University Medical Center, S-3223 Medical
Center North, Nashville, TN 37232-2372, USA
FEATURES Location/Qualifiers
source 1..5239
/db_xref="H-InvDB:HIT000069478"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="5"
/map="5p15"
CDS 5..3256
/codon_start=1
/product="K-Cl cotransporter KCC4"
/protein_id="AAD39741.1"
/translation="MPTNFTVVPVEAHADGGGDETAERTEAPGTPEGPEPERPSPGDG
NPRENSPFLNNVEVEQESFFEGKNMALFEEEMDSNPMVSSLLNKLANYTNLSQGVVEH
EEDEESRRREAKAPRMGTFIGVYLPCLQNILGVILFLRLTWIVGVAGVLESFLIVAMC
CTCTMLTAISMSAIATNGVVPAGGSYYMISRSLGPEFGGAVGLCFYLGTTFAGAMYIL
GTIEIFLTYISPGAAIFQAEAAGGEAAAMLHNMRVYGTCTLVLMALVVFVGVKYVNKL
ALVFLACVVLSILAIYAGVIKSAFDPPDIPVCLLGNRTLSRRSFDACVKAYGIHNNSA
TSALWGLFCNGSQPSAACDEYFIQNNVTEIQGIPGAASGVFLENLWSTYAHAGAFVEK
KGVPSVPVAEESRASTLPYVLTDIAASFTLLVGIYFPSVTGIMAGSNRSGDLKDAQKS
IPTGTILAIVTTSFIYLSCIVLFGACIEGVVLRDKFGEALQGNLVIGMLAWPSPWVIV
IGSFFSTCGAGLQTLTGAPRLLQAIARDGIVPFLQVFGHGKANGEPTWALLLTVLICE
TGILIASLDSVAPILSMFFLMCYLFVNLACAVQTLLRTPNWRPRFKFYHWTLSFLGMS
LCLALMFICSWYYALSAMLIAGCIYKYIEYRGAEKEWGDGIRGLSLNAARYALLRVEH
GPPHTKNWRPQVLVMLNLDAEQAVKHPRLLSFTSQLKAGKGLTIVGSVLEGTYLDKHM
EAQRAEENIRSLMSTEKTKGFCQLVVSSSLRDGMSHLIQSAGLGGLKHNTVLMAWPAS
WKQEDNPFSWKNFVDTVRDTTAAHQALLVAKNVDSFPQNQERFGGGHIDVWWIVHDGG
MLMLLPFLLRQHKVWRKCRMRIFTVAQVDDNSIQMKKDLQMFLYHLRISAEVEVVEMV
ENDISAFTYERTLMMEQRSQMLKQMQLSKNEQEREAQLIHDRNTASHTAAAARTQAPP
TPDKVQMTWTREKLIAEKYRSRDTSLSGFKDLFSMKPDQSNVRRMHTAVKLNGVVLNK
SQDAQLVLLNMPGPPKNRQGDENYMEFLEVLTEGLNRVLLVRGGGREVITIYS"
BASE COUNT 1015 a 1615 c 1560 g 1049 t
ORIGIN
1 agccatgccc acgaacttta cggtggtgcc cgtggaggct cacgccgacg gcggcgggga
61 cgagactgcc gagcggacgg aggctccggg cacccccgag ggccccgagc ccgagcgccc
121 cagcccggga gatggaaatc caagagaaaa cagcccattc ctcaacaatg tcgaggtgga
181 acaagagagc ttctttgaag ggaagaacat ggcacttttc gaggaggaga tggacagtaa
241 ccccatggtg tcctcgctgc tcaacaagct ggccaactac accaacctga gccagggcgt
301 ggtggagcac gaggaggacg aggagagccg gcggcgggag gccaaggctc cgcgcatggg
361 caccttcatc ggcgtctacc tgccgtgcct gcagaacatc ctgggcgtca tcctcttcct
421 gcgcctgacg tggatcgtgg gggtggctgg tgtcctggag tccttcctca tcgtggccat
481 gtgctgcaca tgtacaatgc tgaccgccat ttccatgagt gcgatcgcta ccaacggtgt
541 ggtcccagct ggcgggtcct actacatgat atcgcgctcg ctgggacccg agtttggagg
601 cgctgtcggc ctctgcttct acctgggcac gacgtttgca ggggccatgt atattttggg
661 gaccatcgag atttttctga cgtacatctc cccgggtgcg gccatcttcc aggcggaggc
721 tgcaggtggc gaggcggccg ccatgctgca caacatgcgt gtgtacggca cgtgcacgct
781 cgtgctcatg gccctggtgg tcttcgtggg cgtcaagtat gtcaacaagc tggcgctggt
841 cttcctggcc tgcgtcgtgc tgtccatcct ggccatctat gccggcgtca tcaagtctgc
901 cttcgacccc ccggacatcc cggtctgcct cctggggaac cgcacgctgt cacggcgcag
961 cttcgatgcc tgcgtcaagg cctacggcat ccacaacaac tcagccacct ccgcgctctg
1021 gggcctcttc tgcaacggct cccagcccag cgccgcctgt gacgagtact tcatccagaa
1081 caacgtcacc gaaatccagg gcatcccggg cgcggccagt ggtgtcttcc tggagaacct
1141 gtggagtacg tacgcgcacg cgggggcgtt tgtggagaag aaaggtgtgc cctcggtgcc
1201 cgtggcagag gagagccgtg ccagcacact gccctacgtg ctcaccgaca tcgcggcctc
1261 cttcaccctg ctggttggca tctacttccc ttccgtgacc ggtatcatgg cgggttcaaa
1321 ccggtccggg gacctcaagg atgcacagaa gtccatcccc acggggacca tcctggccat
1381 agtgacgacg tctttcatct atctctcctg cattgtgctg tttggggcct gcattgaagg
1441 cgtggtctta cgagataagt tcggggaggc cctgcagggg aacctggtca tcggcatgct
1501 ggcctggccc tccccctggg tcatcgtcat cggctccttc ttctccacct gcggtgccgg
1561 cctgcagacc ctcacggggg caccgcgcct actgcaggcc attgcccgtg acggcatcgt
1621 ccccttcctg caggtgtttg gccacgggaa ggccaacggg gagcccacgt gggcgctgct
1681 gctgacagtc ctcatctgcg agactggcat cctcatcgcc tctctggaca gcgtggcccc
1741 gatcctctcc atgttcttcc tcatgtgcta cctgttcgtg aacctggcct gcgccgtgca
1801 gaccctgcta cgtaccccca actggcgtcc acgcttcaag ttctaccact ggaccctgtc
1861 ctttctgggt atgagcctgt gcctggcgct gatgttcatc tgctcctggt actacgcgct
1921 gtccgccatg ctcatcgctg gctgcatcta caagtacatc gagtaccgcg gggccgagaa
1981 ggagtggggc gatggcatcc gtggcctatc cctgaacgcc gcccgctacg ccctgctgcg
2041 cgtggagcac ggtccccccc acaccaagaa ctggaggccc caggtgctgg tgatgctgaa
2101 cctggacgcg gagcaggccg tgaagcaccc ccgcctgctg tccttcacgt cgcagctgaa
2161 ggccggcaag ggcctgacca tcgtgggctc ggtgctggag gggacgtacc tggacaagca
2221 catggaggct cagcgggccg aggagaacat acggtcccta atgagcacag agaagaccaa
2281 gggcttctgc cagctggtgg tctcgtccag cctgcgggat ggcatgtccc acctgatcca
2341 gtcggccggc ctgggcggcc tgaagcacaa cacggtgctc atggcctggc ccgcatcctg
2401 gaagcaggag gacaacccct tctcctggaa gaactttgta gacaccgtcc gcgacaccac
2461 cgccgcgcac caggctctgc tggtggccaa gaacgtcgac tcgtttccgc aaaaccagga
2521 gcgcttcggc gggggccaca tcgacgtgtg gtggatcgtg cacgacggcg gcatgctcat
2581 gctgctgccc ttcctgctgc gccagcacaa ggtgtggagg aagtgccgga tgcgtatctt
2641 caccgtggcc caggtggacg acaacagcat ccagatgaag aaggacctgc agatgttctt
2701 gtatcacttg cgcatcagcg ccgaggtgga ggtggtggag atggttgaaa acgacatatc
2761 tgctttcacc tacgagagga cactaatgat ggagcagagg tcgcagatgc tgaagcagat
2821 gcagctgtcc aagaacgagc aggagcgaga ggcccagctg atccacgaca ggaacaccgc
2881 gtcccacacc gcggcggcag ccaggaccca agcgccgcct acgccagaca aggtgcagat
2941 gacctggacc agggagaagc tgatcgctga gaagtacagg agcagagaca ccagcctatc
3001 cggtttcaaa gacctcttca gcatgaagcc ggaccagtcc aacgtcaggc ggatgcacac
3061 ggctgtgaag ctcaatggcg tcgtcctcaa caagtcccag gatgcgcagc tggtcctgct
3121 caacatgcca ggtcctccca aaaaccggca gggagacgag aactacatgg agtttcttga
3181 agtcctgacc gaggggctga acagagtcct cctggtcagg ggtggcggcc gggaggtgat
3241 caccatctac tcctaatgcc caacagcatc acggcactct gggacaggca cggaggacgg
3301 cgtgggcagc ctgggcctgg gcttggccca gggaaccaga cggcagacac acctgtcccc
3361 cagtgatgcc acccaagctg cccatggggc ttcctacgga agtttctagg cccgtcacct
3421 agggctctcc tgttcagcct taacaggctc agcaaatcag ggcgtggctg gacgatttcc
3481 ttgcatctga gggcagacgc tgctaccgga gtgacctgga cgtggccaga tcttctcgca
3541 ggtcacaaga agccagtgag cccttgcctt ggtttctgga agttcttttc cttggctgga
3601 tttacccagt ggttaggttg catttctacc ccatccagaa cattcttgga agagcacccg
3661 gagctgaagc tgtccctgat gatgaaggtg aaacgtcagc cctggccatg gctccgctca
3721 gggccccggt cacctccgag tcactctgtt ccttgactgt ctttgtgttt ctgtacctca
3781 aggcactgaa gctggaggac tctgtccatg cccgtgtcac cctcgtgtgg gagcctctgg
3841 gctcggcagg tccacatttc atgagctgag gcgtgggcca gggccatctg gaaagggaac
3901 tcggcttttc cagaacgtgg tggatcatct gtcgggtgtg tggtgaacac gttcagttca
3961 tcagggccta cgctccggga aggggccccc agctgtggct ctgccatgcc gggctgtgtt
4021 tgcagctgtc cgagtctcca tccaccttta gaaaaccagt cacttctttt cataagcact
4081 gacagggccc agcccacagc cacaggtgcg atcagtgcct cacgcaggca aatgcactga
4141 aacccagggg cacacgcgcg cagagtgaac agtgagttcc cccgacagcc cacgacagcc
4201 aggactgccc tccccacccc accccacccc aggagcacgg cacacagttc agcctctgag
4261 ctggctcaca cgtgccatcc ccaccccggt gctccaggga aggaggacac ggacccgacg
4321 tgggaggtcc tcaggcagca gtggcgcctg gtgtcaggtc tgtctggctg agtcccgggc
4381 gtcccctgcc atggcctgtg ccttgcatgg aggcggcggt ggcactgaag agatagcttt
4441 caagggccca acactttgca cttcggctgg ctgtgagttt ctgctttgta ggttgtggtc
4501 acatttgcag gctgcgggca gtggcaccga cttgggcctc cctttctatg tggcatattt
4561 atttatttaa acaccccagg gagttacgtg gtaacaaggt tgtccataaa gaggttgctt
4621 ctatatacta gaggccccag atggcaggcc ttgggctacg tctggcttgc atggtctccc
4681 aagggaatca accccatcaa caaagttcaa atcggggcag aggctgcact tgtgccccca
4741 gatgtttctg aggagccaga ttagggctgg cattgctgta gagtgacggc tgctgcccag
4801 agcgtgtccc agacatcaca gcggggctca gcagttccca cagcctctgc ctgccttggc
4861 taagcatgag ttaagcagca aaacgctcct ccatgtctgg atggggccgg caggtcctgt
4921 gtcccctgca cctggaggag agcaggctag aggcacagcg gccacatggt gctggctctg
4981 aacgttggtt ggtggctgga aaacagccct gcttctgagg gccgctcagt tctgcacacg
5041 aaaccacctc ctgagggctc agctctgccc ccgccctggg ctgcagcctc tgcacgcaag
5101 caccaggcat cctttgtgtt gtcaactccg tgtaaccagt aactacagcc atttacaatt
5161 gactccgttt ccttttgtag gtttccctgt ctgtctgtgt tagtagaaaa ataaaatcct
5221 atgaaatctg aaaaaaaaa
//